Peroxisomal_enoyl-coa_hydratase_putative/GeneDB:L mjF.18.0580

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

peroxisomal enoyl-coa hydratase, putative

Species:

Leishmania donovani

UniProt:

A0A3S7WUX8_LEIDO

TriTrypDb:

LdBPK_180580.1 , LdCL_180010700 , LDHU3_18.0730

Length:

323

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 8

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 1, no: 7
NetGPI	no	yes: 0, no: 8

Show entries

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	1
GO:0110165	cellular anatomical entity	1	1

Previous1Next

Expansion

Sequence features

A0A3S7WUX8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WUX8

Function

Show entries

Biological processes
Term	Name	Level	Count
GO:0006082	organic acid metabolic process	3	9
GO:0006629	lipid metabolic process	3	9
GO:0006631	fatty acid metabolic process	4	9
GO:0006635	fatty acid beta-oxidation	6	9
GO:0008152	metabolic process	1	9
GO:0009056	catabolic process	2	9
GO:0009062	fatty acid catabolic process	5	9
GO:0009987	cellular process	1	9
GO:0016042	lipid catabolic process	4	9
GO:0016054	organic acid catabolic process	4	9

Previous1 2 3Next

Show entries

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	9
GO:0004300	enoyl-CoA hydratase activity	5	6
GO:0016829	lyase activity	2	6
GO:0016835	carbon-oxygen lyase activity	3	6
GO:0016836	hydro-lyase activity	4	6
GO:0016853	isomerase activity	2	1
GO:0016860	intramolecular oxidoreductase activity	3	1
GO:0016863	intramolecular oxidoreductase activity, transposing C=C bonds	4	1
GO:0051750	delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity	5	1

Previous1Next

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_MEL_PAP_1	16	22	PF00089	0.410
CLV_NRD_NRD_1	18	20	PF00675	0.493
CLV_NRD_NRD_1	241	243	PF00675	0.387
CLV_PCSK_KEX2_1	18	20	PF00082	0.453
CLV_PCSK_KEX2_1	2	4	PF00082	0.694
CLV_PCSK_KEX2_1	243	245	PF00082	0.447
CLV_PCSK_KEX2_1	301	303	PF00082	0.453
CLV_PCSK_PC1ET2_1	2	4	PF00082	0.730
CLV_PCSK_PC1ET2_1	243	245	PF00082	0.402
CLV_PCSK_PC1ET2_1	301	303	PF00082	0.424

Previous1 2 3 4 5…8Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HVP1	Leptomonas seymouri	72%	100%
A0A0S4J4R9	Bodo saltans	42%	97%
A0A0S4JCT1	Bodo saltans	26%	100%
A0A0S4JWH0	Bodo saltans	27%	100%
A0A1X0NJ83	Trypanosomatidae	27%	100%
A0A3Q8IIZ5	Leishmania donovani	31%	100%
A0A3Q8IV04	Leishmania donovani	29%	100%
A0A3R7KI60	Trypanosoma rangeli	26%	100%
A0PJR5	Danio rerio	26%	100%
A4H9G6	Leishmania braziliensis	85%	100%

Previous1 2 3 4 5…8Next