Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3S7WUT3_LEIDO

TriTrypDb:

LdBPK_171280.1 , LdCL_170019000 , LDHU3_17.1790

Length:

765

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WUT3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WUT3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	335	339	PF00656	0.582
CLV_C14_Caspase3-7	605	609	PF00656	0.643
CLV_C14_Caspase3-7	717	721	PF00656	0.644
CLV_C14_Caspase3-7	80	84	PF00656	0.422
CLV_NRD_NRD_1	146	148	PF00675	0.511
CLV_NRD_NRD_1	380	382	PF00675	0.528
CLV_NRD_NRD_1	422	424	PF00675	0.638
CLV_NRD_NRD_1	448	450	PF00675	0.587
CLV_NRD_NRD_1	486	488	PF00675	0.431
CLV_NRD_NRD_1	529	531	PF00675	0.524
CLV_NRD_NRD_1	653	655	PF00675	0.613
CLV_NRD_NRD_1	721	723	PF00675	0.643
CLV_NRD_NRD_1	763	765	PF00675	0.640
CLV_PCSK_FUR_1	567	571	PF00082	0.604
CLV_PCSK_FUR_1	761	765	PF00082	0.613
CLV_PCSK_KEX2_1	146	148	PF00082	0.511
CLV_PCSK_KEX2_1	380	382	PF00082	0.528
CLV_PCSK_KEX2_1	422	424	PF00082	0.770
CLV_PCSK_KEX2_1	448	450	PF00082	0.587
CLV_PCSK_KEX2_1	486	488	PF00082	0.444
CLV_PCSK_KEX2_1	528	530	PF00082	0.493
CLV_PCSK_KEX2_1	569	571	PF00082	0.620
CLV_PCSK_KEX2_1	653	655	PF00082	0.613
CLV_PCSK_KEX2_1	763	765	PF00082	0.645
CLV_PCSK_PC1ET2_1	569	571	PF00082	0.620
CLV_PCSK_PC7_1	524	530	PF00082	0.492
CLV_PCSK_PC7_1	649	655	PF00082	0.576
CLV_PCSK_SKI1_1	2	6	PF00082	0.582
CLV_PCSK_SKI1_1	486	490	PF00082	0.510
CLV_PCSK_SKI1_1	524	528	PF00082	0.456
CLV_PCSK_SKI1_1	692	696	PF00082	0.636
CLV_PCSK_SKI1_1	704	708	PF00082	0.508
DEG_Nend_UBRbox_1	1	4	PF02207	0.583
DEG_SPOP_SBC_1	170	174	PF00917	0.556
DEG_SPOP_SBC_1	4	8	PF00917	0.593
DEG_SPOP_SBC_1	665	669	PF00917	0.586
DEG_SPOP_SBC_1	77	81	PF00917	0.546
DOC_CKS1_1	23	28	PF01111	0.560
DOC_CKS1_1	230	235	PF01111	0.604
DOC_CYCLIN_yCln2_LP_2	248	254	PF00134	0.626
DOC_MAPK_gen_1	528	536	PF00069	0.388
DOC_MAPK_HePTP_8	526	538	PF00069	0.350
DOC_MAPK_MEF2A_6	39	47	PF00069	0.441
DOC_MAPK_MEF2A_6	529	538	PF00069	0.367
DOC_MAPK_MEF2A_6	542	550	PF00069	0.386
DOC_MAPK_MEF2A_6	68	75	PF00069	0.471
DOC_PP1_RVXF_1	382	389	PF00149	0.557
DOC_PP2B_LxvP_1	192	195	PF13499	0.550
DOC_PP2B_LxvP_1	248	251	PF13499	0.620
DOC_PP2B_LxvP_1	255	258	PF13499	0.577
DOC_PP2B_LxvP_1	27	30	PF13499	0.595
DOC_PP2B_LxvP_1	304	307	PF13499	0.686
DOC_PP2B_LxvP_1	318	321	PF13499	0.577
DOC_PP2B_LxvP_1	623	626	PF13499	0.592
DOC_PP4_FxxP_1	458	461	PF00568	0.509
DOC_PP4_FxxP_1	694	697	PF00568	0.558
DOC_USP7_MATH_1	108	112	PF00917	0.579
DOC_USP7_MATH_1	155	159	PF00917	0.578
DOC_USP7_MATH_1	170	174	PF00917	0.508
DOC_USP7_MATH_1	208	212	PF00917	0.606
DOC_USP7_MATH_1	268	272	PF00917	0.638
DOC_USP7_MATH_1	366	370	PF00917	0.658
DOC_USP7_MATH_1	54	58	PF00917	0.695
DOC_USP7_MATH_1	640	644	PF00917	0.559
DOC_USP7_MATH_1	666	670	PF00917	0.659
DOC_USP7_MATH_1	681	685	PF00917	0.547
DOC_USP7_MATH_1	706	710	PF00917	0.634
DOC_USP7_MATH_1	714	718	PF00917	0.601
DOC_WW_Pin1_4	138	143	PF00397	0.485
DOC_WW_Pin1_4	19	24	PF00397	0.594
DOC_WW_Pin1_4	190	195	PF00397	0.574
DOC_WW_Pin1_4	224	229	PF00397	0.635
DOC_WW_Pin1_4	316	321	PF00397	0.589
DOC_WW_Pin1_4	326	331	PF00397	0.607
DOC_WW_Pin1_4	362	367	PF00397	0.683
DOC_WW_Pin1_4	456	461	PF00397	0.560
DOC_WW_Pin1_4	56	61	PF00397	0.556
DOC_WW_Pin1_4	611	616	PF00397	0.839
DOC_WW_Pin1_4	693	698	PF00397	0.569
LIG_14-3-3_CanoR_1	135	144	PF00244	0.590
LIG_14-3-3_CanoR_1	332	337	PF00244	0.645
LIG_14-3-3_CanoR_1	381	387	PF00244	0.719
LIG_14-3-3_CanoR_1	464	469	PF00244	0.433
LIG_14-3-3_CanoR_1	486	495	PF00244	0.469
LIG_14-3-3_CanoR_1	583	593	PF00244	0.600
LIG_14-3-3_CanoR_1	653	658	PF00244	0.622
LIG_BRCT_BRCA1_1	139	143	PF00533	0.457
LIG_BRCT_BRCA1_1	454	458	PF00533	0.555
LIG_deltaCOP1_diTrp_1	134	143	PF00928	0.470
LIG_DLG_GKlike_1	464	471	PF00625	0.397
LIG_FHA_1	139	145	PF00498	0.521
LIG_FHA_1	187	193	PF00498	0.563
LIG_FHA_1	19	25	PF00498	0.600
LIG_FHA_1	329	335	PF00498	0.625
LIG_FHA_1	552	558	PF00498	0.622
LIG_FHA_1	585	591	PF00498	0.683
LIG_FHA_1	59	65	PF00498	0.568
LIG_FHA_1	668	674	PF00498	0.559
LIG_FHA_1	97	103	PF00498	0.526
LIG_FHA_2	292	298	PF00498	0.499
LIG_FHA_2	656	662	PF00498	0.612
LIG_FHA_2	78	84	PF00498	0.476
LIG_LIR_Apic_2	455	461	PF02991	0.531
LIG_LIR_Apic_2	669	675	PF02991	0.628
LIG_LIR_Apic_2	691	697	PF02991	0.575
LIG_LIR_Gen_1	196	206	PF02991	0.546
LIG_LIR_Nem_3	196	202	PF02991	0.540
LIG_MYND_1	316	320	PF01753	0.583
LIG_MYND_1	621	625	PF01753	0.591
LIG_MYND_3	592	596	PF01753	0.585
LIG_SH2_STAP1	148	152	PF00017	0.523
LIG_SH2_STAP1	478	482	PF00017	0.394
LIG_SH2_STAT5	183	186	PF00017	0.586
LIG_SH2_STAT5	672	675	PF00017	0.575
LIG_SH3_3	111	117	PF00018	0.516
LIG_SH3_3	20	26	PF00018	0.556
LIG_SH3_3	314	320	PF00018	0.727
LIG_SH3_3	369	375	PF00018	0.678
LIG_SH3_3	44	50	PF00018	0.532
LIG_SH3_3	554	560	PF00018	0.619
LIG_SH3_3	612	618	PF00018	0.830
LIG_SH3_4	215	222	PF00018	0.531
LIG_SUMO_SIM_anti_2	545	551	PF11976	0.480
LIG_SUMO_SIM_anti_2	72	77	PF11976	0.517
LIG_SUMO_SIM_par_1	40	46	PF11976	0.466
LIG_TRAF2_1	375	378	PF00917	0.559
LIG_TRAF2_1	92	95	PF00917	0.465
LIG_WW_2	322	325	PF00397	0.680
LIG_WW_3	459	463	PF00397	0.529
MOD_CDC14_SPxK_1	329	332	PF00782	0.572
MOD_CDC14_SPxK_1	459	462	PF00782	0.536
MOD_CDK_SPxK_1	229	235	PF00069	0.549
MOD_CDK_SPxK_1	326	332	PF00069	0.577
MOD_CDK_SPxK_1	456	462	PF00069	0.556
MOD_CK1_1	128	134	PF00069	0.560
MOD_CK1_1	158	164	PF00069	0.607
MOD_CK1_1	193	199	PF00069	0.606
MOD_CK1_1	259	265	PF00069	0.606
MOD_CK1_1	282	288	PF00069	0.636
MOD_CK1_1	3	9	PF00069	0.595
MOD_CK1_1	305	311	PF00069	0.737
MOD_CK1_1	434	440	PF00069	0.595
MOD_CK1_1	578	584	PF00069	0.695
MOD_CK1_1	58	64	PF00069	0.620
MOD_CK1_1	599	605	PF00069	0.612
MOD_CK1_1	610	616	PF00069	0.699
MOD_CK1_1	693	699	PF00069	0.573
MOD_CK1_1	716	722	PF00069	0.615
MOD_CK2_1	296	302	PF00069	0.584
MOD_CK2_1	599	605	PF00069	0.763
MOD_Cter_Amidation	144	147	PF01082	0.523
MOD_Cter_Amidation	446	449	PF01082	0.602
MOD_Cter_Amidation	651	654	PF01082	0.607
MOD_Cter_Amidation	761	764	PF01082	0.572
MOD_DYRK1A_RPxSP_1	138	142	PF00069	0.462
MOD_GlcNHglycan	110	113	PF01048	0.588
MOD_GlcNHglycan	127	130	PF01048	0.466
MOD_GlcNHglycan	2	5	PF01048	0.595
MOD_GlcNHglycan	261	264	PF01048	0.712
MOD_GlcNHglycan	287	290	PF01048	0.644
MOD_GlcNHglycan	433	436	PF01048	0.640
MOD_GlcNHglycan	452	455	PF01048	0.555
MOD_GlcNHglycan	517	520	PF01048	0.469
MOD_GlcNHglycan	561	564	PF01048	0.593
MOD_GlcNHglycan	577	580	PF01048	0.625
MOD_GlcNHglycan	600	604	PF01048	0.591
MOD_GlcNHglycan	642	645	PF01048	0.648
MOD_GlcNHglycan	650	653	PF01048	0.590
MOD_GlcNHglycan	685	688	PF01048	0.618
MOD_GlcNHglycan	727	730	PF01048	0.605
MOD_GlcNHglycan	736	739	PF01048	0.636
MOD_GSK3_1	18	25	PF00069	0.533
MOD_GSK3_1	186	193	PF00069	0.534
MOD_GSK3_1	3	10	PF00069	0.596
MOD_GSK3_1	307	314	PF00069	0.768
MOD_GSK3_1	328	335	PF00069	0.561
MOD_GSK3_1	362	369	PF00069	0.685
MOD_GSK3_1	434	441	PF00069	0.771
MOD_GSK3_1	450	457	PF00069	0.529
MOD_GSK3_1	52	59	PF00069	0.626
MOD_GSK3_1	584	591	PF00069	0.510
MOD_GSK3_1	606	613	PF00069	0.706
MOD_GSK3_1	679	686	PF00069	0.656
MOD_GSK3_1	725	732	PF00069	0.581
MOD_LATS_1	14	20	PF00433	0.606
MOD_N-GLC_1	19	24	PF02516	0.556
MOD_N-GLC_1	366	371	PF02516	0.693
MOD_N-GLC_1	723	728	PF02516	0.639
MOD_NEK2_1	171	176	PF00069	0.652
MOD_NEK2_1	222	227	PF00069	0.551
MOD_NEK2_1	382	387	PF00069	0.585
MOD_NEK2_1	5	10	PF00069	0.599
MOD_NEK2_1	548	553	PF00069	0.451
MOD_NEK2_1	96	101	PF00069	0.522
MOD_PIKK_1	279	285	PF00454	0.668
MOD_PIKK_1	296	302	PF00454	0.510
MOD_PIKK_1	356	362	PF00454	0.550
MOD_PIKK_1	548	554	PF00454	0.669
MOD_PIKK_1	624	630	PF00454	0.581
MOD_PKA_1	486	492	PF00069	0.432
MOD_PKA_1	653	659	PF00069	0.602
MOD_PKA_2	137	143	PF00069	0.506
MOD_PKA_2	259	265	PF00069	0.588
MOD_PKA_2	486	492	PF00069	0.438
MOD_PKA_2	495	501	PF00069	0.412
MOD_PKA_2	648	654	PF00069	0.602
MOD_PKB_1	462	470	PF00069	0.465
MOD_Plk_1	690	696	PF00069	0.627
MOD_Plk_4	171	177	PF00069	0.562
MOD_Plk_4	262	268	PF00069	0.681
MOD_ProDKin_1	138	144	PF00069	0.480
MOD_ProDKin_1	19	25	PF00069	0.593
MOD_ProDKin_1	190	196	PF00069	0.577
MOD_ProDKin_1	224	230	PF00069	0.634
MOD_ProDKin_1	316	322	PF00069	0.588
MOD_ProDKin_1	326	332	PF00069	0.605
MOD_ProDKin_1	362	368	PF00069	0.684
MOD_ProDKin_1	456	462	PF00069	0.556
MOD_ProDKin_1	56	62	PF00069	0.553
MOD_ProDKin_1	611	617	PF00069	0.835
MOD_ProDKin_1	693	699	PF00069	0.566
TRG_DiLeu_BaEn_1	545	550	PF01217	0.401
TRG_DiLeu_BaEn_4	377	383	PF01217	0.556
TRG_DiLeu_BaEn_4	505	511	PF01217	0.462
TRG_ER_diArg_1	146	148	PF00400	0.514
TRG_ER_diArg_1	380	382	PF00400	0.542
TRG_ER_diArg_1	461	464	PF00400	0.485
TRG_ER_diArg_1	485	487	PF00400	0.432
TRG_ER_diArg_1	527	530	PF00400	0.494
TRG_ER_diArg_1	653	655	PF00400	0.613
TRG_ER_diArg_1	761	764	PF00400	0.632
TRG_NES_CRM1_1	525	537	PF08389	0.350
TRG_Pf-PMV_PEXEL_1	49	53	PF00026	0.557

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I049	Leptomonas seymouri	36%	80%
A4H973	Leishmania braziliensis	59%	100%
A4HXJ5	Leishmania infantum	98%	100%
E9AR90	Leishmania mexicana (strain MHOM/GT/2001/U1103)	81%	100%
Q4QE73	Leishmania major	86%	100%