LeishMANIAdb
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HTH La-type RNA-binding domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
HTH La-type RNA-binding domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7WUF4_LEIDO
TriTrypDb:
LdBPK_170760.1 * , LdCL_170013300 , LDHU3_17.1100
Length:
439

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 7
NetGPI no yes: 0, no: 7
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WUF4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WUF4

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 224 228 PF00656 0.652
CLV_C14_Caspase3-7 264 268 PF00656 0.436
CLV_C14_Caspase3-7 30 34 PF00656 0.660
CLV_NRD_NRD_1 140 142 PF00675 0.690
CLV_NRD_NRD_1 279 281 PF00675 0.564
CLV_NRD_NRD_1 60 62 PF00675 0.595
CLV_PCSK_KEX2_1 408 410 PF00082 0.465
CLV_PCSK_PC1ET2_1 408 410 PF00082 0.465
CLV_PCSK_SKI1_1 145 149 PF00082 0.658
CLV_PCSK_SKI1_1 296 300 PF00082 0.466
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P3C3 Leptomonas seymouri 67% 95%
A4H912 Leishmania braziliensis 73% 100%
A4HXE4 Leishmania infantum 99% 100%
E9AR39 Leishmania mexicana (strain MHOM/GT/2001/U1103) 86% 100%
Q4QEC4 Leishmania major 90% 100%
V5D5C0 Trypanosoma cruzi 34% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS