LSM domain containing protein, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7WUC9_LEIDO

TriTrypDb:

LdBPK_170350.1 , LdCL_170009000 , LDHU3_17.0620

Length:

203

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WUC9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WUC9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	9	13	PF00656	0.734
CLV_NRD_NRD_1	186	188	PF00675	0.493
CLV_NRD_NRD_1	70	72	PF00675	0.258
CLV_PCSK_FUR_1	186	190	PF00082	0.484
CLV_PCSK_KEX2_1	186	188	PF00082	0.544
CLV_PCSK_KEX2_1	70	72	PF00082	0.274
CLV_PCSK_PC1ET2_1	188	190	PF00082	0.509
CLV_PCSK_SKI1_1	79	83	PF00082	0.254
DEG_Nend_UBRbox_1	1	4	PF02207	0.590
DOC_USP7_MATH_1	150	154	PF00917	0.553
DOC_USP7_MATH_1	192	196	PF00917	0.486
DOC_USP7_MATH_1	33	37	PF00917	0.625
LIG_14-3-3_CanoR_1	70	76	PF00244	0.564
LIG_14-3-3_CanoR_1	91	101	PF00244	0.588
LIG_BIR_III_4	138	142	PF00653	0.468
LIG_Clathr_ClatBox_1	53	57	PF01394	0.450
LIG_FHA_1	109	115	PF00498	0.559
LIG_FHA_1	143	149	PF00498	0.596
LIG_FHA_1	24	30	PF00498	0.631
LIG_FHA_1	48	54	PF00498	0.524
LIG_LIR_Gen_1	162	171	PF02991	0.539
LIG_LIR_Gen_1	57	68	PF02991	0.532
LIG_Pex14_2	132	136	PF04695	0.532
LIG_SH2_STAT5	120	123	PF00017	0.437
LIG_SH2_STAT5	125	128	PF00017	0.437
LIG_SH2_STAT5	47	50	PF00017	0.437
LIG_TRAF2_1	86	89	PF00917	0.391
MOD_CK1_1	11	17	PF00069	0.628
MOD_CK1_1	149	155	PF00069	0.580
MOD_CK1_1	162	168	PF00069	0.436
MOD_CK1_1	27	33	PF00069	0.523
MOD_CK2_1	107	113	PF00069	0.563
MOD_CK2_1	83	89	PF00069	0.464
MOD_GlcNHglycan	148	151	PF01048	0.582
MOD_GlcNHglycan	154	157	PF01048	0.418
MOD_GlcNHglycan	194	197	PF01048	0.692
MOD_GlcNHglycan	21	24	PF01048	0.672
MOD_GSK3_1	121	128	PF00069	0.595
MOD_GSK3_1	142	149	PF00069	0.658
MOD_GSK3_1	19	26	PF00069	0.574
MOD_GSK3_1	27	34	PF00069	0.564
MOD_NEK2_1	167	172	PF00069	0.547
MOD_NEK2_1	24	29	PF00069	0.639
MOD_NEK2_1	92	97	PF00069	0.595
MOD_PIKK_1	83	89	PF00454	0.497
MOD_PK_1	127	133	PF00069	0.412
MOD_Plk_1	162	168	PF00069	0.367
MOD_Plk_4	121	127	PF00069	0.465
TRG_DiLeu_BaLyEn_6	88	93	PF01217	0.453
TRG_ENDOCYTIC_2	60	63	PF00928	0.541
TRG_ER_diArg_1	116	119	PF00400	0.474
TRG_ER_diArg_1	180	183	PF00400	0.459
TRG_ER_diArg_1	186	189	PF00400	0.469
TRG_ER_diArg_1	69	71	PF00400	0.524

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HUV2	Leptomonas seymouri	48%	78%
A0A1X0NSZ2	Trypanosomatidae	35%	91%
A0A422N3W3	Trypanosoma rangeli	37%	76%
A4H8X3	Leishmania braziliensis	74%	100%
A4HX97	Leishmania infantum	100%	100%
C9ZTX0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	32%	99%
E9AQZ9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
Q4QEG4	Leishmania major	92%	100%
V5BH99	Trypanosoma cruzi	36%	94%