Anaphase-promoting complex subunit 11 RING-H2 finger/Zinc finger, C3HC4 type (RING finger)/Ring finger domain/RING-H2 zinc finger containing protein, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Ring finger domain containing protein, putative

Species:

Leishmania donovani

UniProt:

A0A3S7WU93_LEIDO

TriTrypDb:

LdBPK_170040.1 , LdCL_170005400 , LDHU3_17.0060

Length:

211

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WU93

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WU93

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	141	143	PF00675	0.556
CLV_NRD_NRD_1	193	195	PF00675	0.609
CLV_PCSK_FUR_1	138	142	PF00082	0.602
CLV_PCSK_KEX2_1	138	140	PF00082	0.546
CLV_PCSK_KEX2_1	141	143	PF00082	0.553
CLV_PCSK_SKI1_1	157	161	PF00082	0.662
DEG_Nend_Nbox_1	1	3	PF02207	0.605
DOC_CKS1_1	160	165	PF01111	0.753
DOC_CKS1_1	167	172	PF01111	0.640
DOC_CYCLIN_yCln2_LP_2	89	95	PF00134	0.411
DOC_MAPK_gen_1	138	145	PF00069	0.592
DOC_PP2B_LxvP_1	145	148	PF13499	0.650
DOC_PP4_FxxP_1	3	6	PF00568	0.598
DOC_USP7_MATH_1	35	39	PF00917	0.706
DOC_USP7_MATH_1	43	47	PF00917	0.570
DOC_USP7_MATH_1	49	53	PF00917	0.619
DOC_WW_Pin1_4	159	164	PF00397	0.753
DOC_WW_Pin1_4	166	171	PF00397	0.635
DOC_WW_Pin1_4	2	7	PF00397	0.603
LIG_14-3-3_CanoR_1	111	117	PF00244	0.411
LIG_14-3-3_CanoR_1	130	137	PF00244	0.356
LIG_FHA_1	67	73	PF00498	0.589
LIG_FHA_1	77	83	PF00498	0.411
LIG_PTAP_UEV_1	147	152	PF05743	0.561
LIG_Rb_LxCxE_1	99	115	PF01857	0.411
LIG_SH2_GRB2like	57	60	PF00017	0.728
LIG_SH2_STAT5	2	5	PF00017	0.611
LIG_SH2_STAT5	57	60	PF00017	0.728
LIG_SH3_3	145	151	PF00018	0.657
LIG_SUMO_SIM_anti_2	183	190	PF11976	0.696
LIG_SUMO_SIM_par_1	187	193	PF11976	0.649
MOD_CK1_1	38	44	PF00069	0.723
MOD_CK1_1	52	58	PF00069	0.484
MOD_CK2_1	169	175	PF00069	0.670
MOD_GlcNHglycan	148	151	PF01048	0.599
MOD_GlcNHglycan	37	40	PF01048	0.637
MOD_GSK3_1	190	197	PF00069	0.632
MOD_GSK3_1	2	9	PF00069	0.602
MOD_GSK3_1	43	50	PF00069	0.593
MOD_N-GLC_1	52	57	PF02516	0.620
MOD_PK_1	194	200	PF00069	0.519
MOD_PKA_1	194	200	PF00069	0.519
MOD_PKA_2	112	118	PF00069	0.411
MOD_PKA_2	20	26	PF00069	0.681
MOD_Plk_1	59	65	PF00069	0.632
MOD_Plk_2-3	177	183	PF00069	0.772
MOD_Plk_2-3	66	72	PF00069	0.710
MOD_Plk_2-3	85	91	PF00069	0.213
MOD_Plk_4	20	26	PF00069	0.656
MOD_Plk_4	59	65	PF00069	0.656
MOD_ProDKin_1	159	165	PF00069	0.753
MOD_ProDKin_1	166	172	PF00069	0.640
MOD_ProDKin_1	2	8	PF00069	0.603
MOD_SUMO_for_1	96	99	PF00179	0.411
TRG_DiLeu_BaEn_1	156	161	PF01217	0.684
TRG_ER_diArg_1	110	113	PF00400	0.411
TRG_ER_diArg_1	137	140	PF00400	0.538
TRG_ER_diArg_1	141	143	PF00400	0.548

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2S1	Leptomonas seymouri	62%	100%
A4H8U9	Leishmania braziliensis	75%	100%
A4HX68	Leishmania infantum	100%	100%
E9ARC5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
Q4QEJ5	Leishmania major	91%	100%