LeishMANIAdb
  • Home
  • Browse
  • Manual
  • FAQ
  • Download

B30.2/SPRY domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
B30.2/SPRY domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7WU73_LEIDO
TriTrypDb:
LdBPK_161620.1 , LdCL_160021200 , LDHU3_16.1920
Length:
1150

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Cellular components
TermNameLevelCount
GO:0031298 replication fork protection complex 3 1
GO:0032991 protein-containing complex 1 1
GO:0140513 nuclear protein-containing complex 2 1
Previous1Next

Expansion

Sequence features

A0A3S7WU73
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WU73

Function

Biological processes
TermNameLevelCount
GO:0000075 cell cycle checkpoint signaling 4 1
GO:0000076 DNA replication checkpoint signaling 6 1
GO:0006139 nucleobase-containing compound metabolic process 3 1
GO:0006259 DNA metabolic process 4 1
GO:0006275 regulation of DNA replication 6 1
GO:0006281 DNA repair 5 1
GO:0006725 cellular aromatic compound metabolic process 3 1
GO:0006807 nitrogen compound metabolic process 2 1
GO:0006950 response to stress 2 1
GO:0006974 DNA damage response 4 1
Previous123456Next
Molecular functions
TermNameLevelCount
GO:0003676 nucleic acid binding 3 1
GO:0003677 DNA binding 4 1
GO:0005488 binding 1 1
GO:0097159 organic cyclic compound binding 2 1
GO:1901363 heterocyclic compound binding 2 1
Previous1Next

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 1038 1042 PF00656 0.715
CLV_C14_Caspase3-7 1105 1109 PF00656 0.579
CLV_C14_Caspase3-7 728 732 PF00656 0.630
CLV_NRD_NRD_1 1025 1027 PF00675 0.617
CLV_NRD_NRD_1 1028 1030 PF00675 0.615
CLV_NRD_NRD_1 1077 1079 PF00675 0.736
CLV_NRD_NRD_1 1089 1091 PF00675 0.824
CLV_NRD_NRD_1 256 258 PF00675 0.535
CLV_NRD_NRD_1 429 431 PF00675 0.628
CLV_NRD_NRD_1 442 444 PF00675 0.472
Previous12345…42Next

Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1PC20 Leptomonas seymouri 64% 100%
A0A422N424 Trypanosoma rangeli 41% 100%
A4H8T1 Leishmania braziliensis 75% 100%
A4HX50 Leishmania infantum 99% 100%
C9ZVU2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 40% 100%
E9AQW5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 91% 100%
Q4QEL3 Leishmania major 90% 100%
V5BS96 Trypanosoma cruzi 41% 100%
Previous1Next

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS