Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7WU02_LEIDO

TriTrypDb:

LdBPK_160900.1 , LdCL_160014300 , LDHU3_16.1070

Length:

297

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WU02

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WU02

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	192	194	PF00675	0.679
CLV_NRD_NRD_1	30	32	PF00675	0.639
CLV_NRD_NRD_1	87	89	PF00675	0.715
CLV_NRD_NRD_1	98	100	PF00675	0.609
CLV_PCSK_KEX2_1	191	193	PF00082	0.682
CLV_PCSK_KEX2_1	30	32	PF00082	0.643
CLV_PCSK_KEX2_1	87	89	PF00082	0.711
CLV_PCSK_KEX2_1	98	100	PF00082	0.677
CLV_PCSK_PC7_1	188	194	PF00082	0.710
CLV_PCSK_SKI1_1	139	143	PF00082	0.618
CLV_PCSK_SKI1_1	192	196	PF00082	0.760
CLV_PCSK_SKI1_1	77	81	PF00082	0.708
CLV_Separin_Metazoa	232	236	PF03568	0.515
DEG_APCC_KENBOX_2	260	264	PF00400	0.731
DEG_SPOP_SBC_1	267	271	PF00917	0.745
DOC_CYCLIN_RxL_1	74	83	PF00134	0.670
DOC_MAPK_gen_1	30	38	PF00069	0.653
DOC_PP1_RVXF_1	137	143	PF00149	0.608
DOC_USP7_MATH_1	134	138	PF00917	0.687
DOC_USP7_MATH_1	149	153	PF00917	0.611
DOC_USP7_MATH_1	267	271	PF00917	0.750
DOC_USP7_MATH_1	275	279	PF00917	0.669
DOC_USP7_MATH_1	289	293	PF00917	0.609
DOC_USP7_MATH_1	37	41	PF00917	0.654
DOC_WW_Pin1_4	285	290	PF00397	0.755
DOC_WW_Pin1_4	50	55	PF00397	0.682
LIG_14-3-3_CanoR_1	139	147	PF00244	0.628
LIG_14-3-3_CanoR_1	19	25	PF00244	0.688
LIG_14-3-3_CanoR_1	66	72	PF00244	0.616
LIG_BIR_II_1	1	5	PF00653	0.671
LIG_EH_1	31	35	PF12763	0.634
LIG_FHA_1	67	73	PF00498	0.648
LIG_FHA_2	178	184	PF00498	0.705
LIG_LIR_Apic_2	164	169	PF02991	0.559
LIG_LIR_Gen_1	104	110	PF02991	0.538
LIG_LIR_Nem_3	104	109	PF02991	0.543
LIG_PDZ_Class_3	292	297	PF00595	0.701
LIG_Pex14_1	102	106	PF04695	0.576
LIG_Rb_LxCxE_1	116	137	PF01857	0.563
LIG_SH2_CRK	166	170	PF00017	0.728
LIG_SH2_STAT5	227	230	PF00017	0.648
LIG_SH3_1	166	172	PF00018	0.725
LIG_SH3_3	166	172	PF00018	0.665
LIG_SH3_3	283	289	PF00018	0.663
LIG_SH3_3	83	89	PF00018	0.678
LIG_SUMO_SIM_par_1	34	41	PF11976	0.628
MOD_CK1_1	202	208	PF00069	0.723
MOD_CK1_1	253	259	PF00069	0.630
MOD_CK1_1	268	274	PF00069	0.762
MOD_CK1_1	288	294	PF00069	0.591
MOD_CK1_1	71	77	PF00069	0.764
MOD_CK2_1	177	183	PF00069	0.773
MOD_CK2_1	289	295	PF00069	0.560
MOD_Cter_Amidation	189	192	PF01082	0.684
MOD_GlcNHglycan	151	154	PF01048	0.705
MOD_GlcNHglycan	201	204	PF01048	0.811
MOD_GlcNHglycan	220	223	PF01048	0.476
MOD_GlcNHglycan	255	258	PF01048	0.700
MOD_GlcNHglycan	277	280	PF01048	0.714
MOD_GlcNHglycan	56	59	PF01048	0.715
MOD_GlcNHglycan	82	85	PF01048	0.700
MOD_GSK3_1	104	111	PF00069	0.609
MOD_GSK3_1	145	152	PF00069	0.637
MOD_GSK3_1	198	205	PF00069	0.697
MOD_GSK3_1	213	220	PF00069	0.560
MOD_GSK3_1	261	268	PF00069	0.769
MOD_GSK3_1	285	292	PF00069	0.562
MOD_GSK3_1	50	57	PF00069	0.717
MOD_GSK3_1	64	71	PF00069	0.523
MOD_N-GLC_1	217	222	PF02516	0.585
MOD_N-GLC_1	265	270	PF02516	0.643
MOD_NEK2_1	265	270	PF00069	0.729
MOD_NEK2_1	6	11	PF00069	0.678
MOD_NEK2_1	80	85	PF00069	0.676
MOD_OFUCOSY	64	70	PF10250	0.647
MOD_PIKK_1	104	110	PF00454	0.638
MOD_PIKK_1	213	219	PF00454	0.679
MOD_PIKK_1	250	256	PF00454	0.573
MOD_PKA_1	87	93	PF00069	0.699
MOD_PKA_2	18	24	PF00069	0.599
MOD_PKA_2	228	234	PF00069	0.577
MOD_PKA_2	65	71	PF00069	0.471
MOD_PKA_2	87	93	PF00069	0.657
MOD_PKB_1	191	199	PF00069	0.677
MOD_Plk_1	261	267	PF00069	0.770
MOD_ProDKin_1	285	291	PF00069	0.756
MOD_ProDKin_1	50	56	PF00069	0.683
TRG_ER_diArg_1	118	121	PF00400	0.317
TRG_ER_diArg_1	191	193	PF00400	0.791
TRG_ER_diArg_1	86	88	PF00400	0.711
TRG_ER_diArg_1	98	100	PF00400	0.617

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P756	Leptomonas seymouri	35%	95%
A4H8L3	Leishmania braziliensis	70%	100%
E9AGN6	Leishmania infantum	99%	100%
E9AQP8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	81%	100%
Q4QES9	Leishmania major	87%	100%