LeishMANIAdb
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Secreted protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Secreted protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7WTQ4_LEIDO
TriTrypDb:
LdBPK_151590.1 , LdCL_150021200
Length:
109

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 3
NetGPI no yes: 0, no: 3
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WTQ4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WTQ4

Putative motif mimicry

Leishmania From To Domain/Motif Score
DEG_SCF_FBW7_1 17 23 PF00400 0.517
DOC_CKS1_1 17 22 PF01111 0.517
DOC_MAPK_MEF2A_6 7 15 PF00069 0.477
DOC_USP7_UBL2_3 56 60 PF12436 0.489
DOC_WW_Pin1_4 16 21 PF00397 0.540
DOC_WW_Pin1_4 95 100 PF00397 0.585
LIG_14-3-3_CanoR_1 7 12 PF00244 0.527
LIG_BIR_II_1 1 5 PF00653 0.525
LIG_BRCT_BRCA1_1 1 5 PF00533 0.520
LIG_BRCT_BRCA1_1 30 34 PF00533 0.512
LIG_BRCT_BRCA1_1 45 49 PF00533 0.432
LIG_FHA_1 8 14 PF00498 0.514
LIG_LIR_Gen_1 10 20 PF02991 0.509
LIG_LIR_Nem_3 10 15 PF02991 0.476
LIG_LIR_Nem_3 2 8 PF02991 0.512
LIG_NRP_CendR_1 106 109 PF00754 0.566
LIG_Pex14_2 35 39 PF04695 0.503
LIG_SH2_PTP2 14 17 PF00017 0.516
LIG_SH2_SRC 12 15 PF00017 0.480
LIG_SH2_SRC 82 85 PF00017 0.495
LIG_SH2_STAP1 30 34 PF00017 0.494
LIG_SH2_STAP1 9 13 PF00017 0.475
LIG_SH2_STAT5 14 17 PF00017 0.498
LIG_SH2_STAT5 9 12 PF00017 0.502
LIG_SH3_2 55 60 PF14604 0.454
LIG_SH3_3 12 18 PF00018 0.701
LIG_SH3_3 52 58 PF00018 0.462
LIG_TYR_ITSM 8 15 PF00017 0.477
LIG_WRC_WIRS_1 36 41 PF05994 0.482
MOD_CDK_SPK_2 21 26 PF00069 0.519
MOD_CK2_1 82 88 PF00069 0.506
MOD_GSK3_1 16 23 PF00069 0.559
MOD_GSK3_1 30 37 PF00069 0.466
MOD_GSK3_1 39 46 PF00069 0.470
MOD_LATS_1 87 93 PF00433 0.576
MOD_N-GLC_1 43 48 PF02516 0.478
MOD_N-GLC_1 95 100 PF02516 0.577
MOD_NEK2_1 34 39 PF00069 0.520
MOD_NEK2_1 45 50 PF00069 0.453
MOD_NEK2_2 30 35 PF00069 0.461
MOD_Plk_4 30 36 PF00069 0.505
MOD_Plk_4 45 51 PF00069 0.519
MOD_Plk_4 7 13 PF00069 0.509
MOD_ProDKin_1 16 22 PF00069 0.540
MOD_ProDKin_1 95 101 PF00069 0.585
TRG_ENDOCYTIC_2 12 15 PF00928 0.517
TRG_ER_diLys_1 104 109 PF00400 0.564

Homologs

Protein Taxonomy Sequence identity Coverage
A4HWP1 Leishmania infantum 99% 100%
Q4QF27 Leishmania major 83% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS