Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7WTE3_LEIDO

TriTrypDb:

LdBPK_150630.1 , LdCL_150011400 , LDHU3_15.0780

Length:

1251

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Show entries

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	6
GO:0110165	cellular anatomical entity	1	6

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Expansion

Sequence features

A0A3S7WTE3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WTE3

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1244	1248	PF00656	0.467
CLV_C14_Caspase3-7	329	333	PF00656	0.692
CLV_C14_Caspase3-7	452	456	PF00656	0.749
CLV_C14_Caspase3-7	476	480	PF00656	0.697
CLV_C14_Caspase3-7	891	895	PF00656	0.803
CLV_C14_Caspase3-7	901	905	PF00656	0.691
CLV_NRD_NRD_1	1126	1128	PF00675	0.473
CLV_NRD_NRD_1	201	203	PF00675	0.437
CLV_NRD_NRD_1	300	302	PF00675	0.482
CLV_NRD_NRD_1	319	321	PF00675	0.457

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I0S2	Leptomonas seymouri	34%	100%
A4H833	Leishmania braziliensis	57%	95%
A4HWF9	Leishmania infantum	99%	100%
E9AQ58	Leishmania mexicana (strain MHOM/GT/2001/U1103)	80%	99%
Q4QFC5	Leishmania major	86%	98%

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