ER membrane protein complex subunit 6

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7WTD5_LEIDO

TriTrypDb:

LdBPK_150470.1 , LdCL_150009600 , LDHU3_15.0570

Length:

146


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	9
GO:0110165	cellular anatomical entity	1	9

A0A3S7WTD5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WTD5


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	130	132	PF00675	0.516
CLV_NRD_NRD_1	85	87	PF00675	0.670
CLV_PCSK_KEX2_1	130	132	PF00082	0.518
CLV_PCSK_KEX2_1	85	87	PF00082	0.650
CLV_PCSK_PC7_1	126	132	PF00082	0.544
CLV_PCSK_SKI1_1	131	135	PF00082	0.520
CLV_PCSK_SKI1_1	86	90	PF00082	0.639
DEG_Nend_UBRbox_3	1	3	PF02207	0.714
DOC_MAPK_DCC_7	60	70	PF00069	0.562
DOC_MAPK_RevD_3	72	86	PF00069	0.447
DOC_PP2B_PxIxI_1	65	71	PF00149	0.441
DOC_WW_Pin1_4	1	6	PF00397	0.562
DOC_WW_Pin1_4	36	41	PF00397	0.739
DOC_WW_Pin1_4	90	95	PF00397	0.362
LIG_14-3-3_CanoR_1	130	139	PF00244	0.740
LIG_14-3-3_CanoR_1	85	95	PF00244	0.501
LIG_FHA_1	132	138	PF00498	0.736
LIG_FHA_1	87	93	PF00498	0.495
LIG_LIR_Gen_1	75	83	PF02991	0.480
LIG_LIR_Nem_3	75	81	PF02991	0.398
LIG_PCNA_PIPBox_1	48	57	PF02747	0.685
LIG_SH2_CRK	78	82	PF00017	0.446
LIG_SH2_STAT5	54	57	PF00017	0.610
LIG_SH3_2	5	10	PF14604	0.714
LIG_SH3_3	14	20	PF00018	0.679
LIG_SH3_3	2	8	PF00018	0.737
LIG_SH3_3	31	37	PF00018	0.772
LIG_SxIP_EBH_1	60	71	PF03271	0.558
LIG_TRAF2_1	24	27	PF00917	0.741
LIG_UBA3_1	51	60	PF00899	0.620
MOD_CDK_SPK_2	1	6	PF00069	0.562
MOD_CK1_1	132	138	PF00069	0.717
MOD_CK2_1	21	27	PF00069	0.733
MOD_GSK3_1	86	93	PF00069	0.477
MOD_N-GLC_1	1	6	PF02516	0.362
MOD_NEK2_1	72	77	PF00069	0.419
MOD_NEK2_1	88	93	PF00069	0.386
MOD_PIKK_1	22	28	PF00454	0.736
MOD_PIKK_1	46	52	PF00454	0.726
MOD_PIKK_1	60	66	PF00454	0.507
MOD_PKA_2	129	135	PF00069	0.740
MOD_Plk_1	46	52	PF00069	0.725
MOD_Plk_4	54	60	PF00069	0.658
MOD_Plk_4	72	78	PF00069	0.225
MOD_ProDKin_1	1	7	PF00069	0.557
MOD_ProDKin_1	36	42	PF00069	0.740
MOD_ProDKin_1	90	96	PF00069	0.362
TRG_ENDOCYTIC_2	78	81	PF00928	0.392
TRG_Pf-PMV_PEXEL_1	107	111	PF00026	0.504


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PAK1	Leptomonas seymouri	73%	100%
A0A0S4JX73	Bodo saltans	40%	100%
A0A1X0NVE4	Trypanosomatidae	46%	100%
A0A3R7RL81	Trypanosoma rangeli	45%	90%
A4H814	Leishmania braziliensis	80%	100%
A4HWE4	Leishmania infantum	99%	100%
C9ZNY5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
E9AQ44	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%
Q4QFD8	Leishmania major	90%	100%