Zinc_finger_(CCCH_type)_protein_putative/GeneDB:L mjF.15.0140

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

zinc finger (CCCH type) protein, putative

Species:

Leishmania donovani

UniProt:

A0A3S7WT90_LEIDO

TriTrypDb:

LdBPK_150140.1 , LdCL_150006300 , LDHU3_15.0190

Length:

215

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0005829	cytosol	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A0A3S7WT90

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WT90

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	6
GO:0003723	RNA binding	4	6
GO:0003729	mRNA binding	5	5
GO:0005488	binding	1	10
GO:0043167	ion binding	2	10
GO:0043169	cation binding	3	10
GO:0046872	metal ion binding	4	10
GO:0097159	organic cyclic compound binding	2	6
GO:1901363	heterocyclic compound binding	2	6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	110	112	PF00675	0.610
CLV_PCSK_FUR_1	107	111	PF00082	0.705
CLV_PCSK_KEX2_1	109	111	PF00082	0.601
CLV_PCSK_SKI1_1	34	38	PF00082	0.369
DOC_CKS1_1	98	103	PF01111	0.763
DOC_MAPK_gen_1	107	117	PF00069	0.594
DOC_MAPK_MEF2A_6	109	117	PF00069	0.629
DOC_MAPK_MEF2A_6	163	172	PF00069	0.517
DOC_PP2B_LxvP_1	172	175	PF13499	0.657
DOC_USP7_MATH_1	168	172	PF00917	0.604
DOC_USP7_MATH_1	190	194	PF00917	0.564
DOC_WW_Pin1_4	126	131	PF00397	0.647
DOC_WW_Pin1_4	164	169	PF00397	0.597
DOC_WW_Pin1_4	75	80	PF00397	0.700
DOC_WW_Pin1_4	97	102	PF00397	0.729
LIG_14-3-3_CanoR_1	109	114	PF00244	0.712
LIG_14-3-3_CanoR_1	187	197	PF00244	0.608
LIG_FHA_1	110	116	PF00498	0.700
LIG_FHA_2	120	126	PF00498	0.679
LIG_FHA_2	132	138	PF00498	0.676
LIG_IBAR_NPY_1	203	205	PF08397	0.584
LIG_LIR_Apic_2	124	130	PF02991	0.683
LIG_LIR_Apic_2	147	151	PF02991	0.655
LIG_LIR_Nem_3	137	143	PF02991	0.717
LIG_REV1ctd_RIR_1	20	29	PF16727	0.444
LIG_SH2_CRK	127	131	PF00017	0.680
LIG_SH2_CRK	148	152	PF00017	0.652
LIG_SH2_STAT3	150	153	PF00017	0.678
LIG_SH2_STAT5	183	186	PF00017	0.690
LIG_SH3_3	112	118	PF00018	0.641
LIG_SH3_3	132	138	PF00018	0.387
LIG_SH3_3	92	98	PF00018	0.712
LIG_SUMO_SIM_par_1	111	116	PF11976	0.632
MOD_CDK_SPxxK_3	100	107	PF00069	0.676
MOD_CK1_1	129	135	PF00069	0.644
MOD_CK1_1	164	170	PF00069	0.597
MOD_CK1_1	80	86	PF00069	0.713
MOD_CK1_1	87	93	PF00069	0.694
MOD_CK2_1	119	125	PF00069	0.682
MOD_CK2_1	131	137	PF00069	0.681
MOD_GlcNHglycan	131	134	PF01048	0.647
MOD_GlcNHglycan	188	191	PF01048	0.603
MOD_GlcNHglycan	86	89	PF01048	0.764
MOD_GSK3_1	10	17	PF00069	0.534
MOD_GSK3_1	109	116	PF00069	0.720
MOD_GSK3_1	164	171	PF00069	0.567
MOD_GSK3_1	186	193	PF00069	0.606
MOD_GSK3_1	73	80	PF00069	0.618
MOD_GSK3_1	82	89	PF00069	0.526
MOD_GSK3_1	93	100	PF00069	0.655
MOD_N-GLC_1	164	169	PF02516	0.607
MOD_NEK2_1	188	193	PF00069	0.559
MOD_NEK2_1	54	59	PF00069	0.574
MOD_OFUCOSY	186	192	PF10250	0.622
MOD_PIKK_1	149	155	PF00454	0.663
MOD_PIKK_1	190	196	PF00454	0.664
MOD_PKA_1	109	115	PF00069	0.708
MOD_PKA_2	109	115	PF00069	0.708
MOD_PKA_2	186	192	PF00069	0.628
MOD_PKB_1	107	115	PF00069	0.709
MOD_ProDKin_1	126	132	PF00069	0.646
MOD_ProDKin_1	164	170	PF00069	0.597
MOD_ProDKin_1	75	81	PF00069	0.695
MOD_ProDKin_1	97	103	PF00069	0.726
MOD_SUMO_rev_2	41	51	PF00179	0.660
TRG_ER_diArg_1	106	109	PF00400	0.620

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I3Y1	Leptomonas seymouri	69%	100%
A0A1X0NV29	Trypanosomatidae	42%	100%
A0A422NSB0	Trypanosoma rangeli	37%	100%
A4H7Y4	Leishmania braziliensis	82%	100%
A4HWB1	Leishmania infantum	100%	100%
C9ZNU9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	100%
E9AQ11	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	100%
Q4QFH0	Leishmania major	94%	100%