LeishMANIAdb
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DUF202 domain-containing protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
DUF202 domain-containing protein
Gene product:
Domain of unknown function (DUF202), putative
Species:
Leishmania donovani
UniProt:
A0A3S7WT40_LEIDO
TriTrypDb:
LdBPK_141100.1 , LdCL_140016700 , LDHU3_14.1370
Length:
180

Annotations

Annotations by Jardim et al.

Acidocalcisome, vacuolar transporter chaperone

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. yes yes: 18
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 11
GO:0110165 cellular anatomical entity 1 11
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Expansion

Sequence features

A0A3S7WT40
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WT40

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_PCSK_KEX2_1 50 52 PF00082 0.452
CLV_PCSK_PC1ET2_1 50 52 PF00082 0.452
CLV_PCSK_SKI1_1 41 45 PF00082 0.465
CLV_PCSK_SKI1_1 61 65 PF00082 0.261
CLV_PCSK_SKI1_1 68 72 PF00082 0.267
CLV_Separin_Metazoa 131 135 PF03568 0.637
DEG_APCC_DBOX_1 67 75 PF00400 0.458
DEG_Nend_UBRbox_2 1 3 PF02207 0.707
DOC_MAPK_MEF2A_6 139 148 PF00069 0.458
DOC_MAPK_MEF2A_6 72 80 PF00069 0.302
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1PA80 Leptomonas seymouri 92% 100%
A0A0S4IYL4 Bodo saltans 69% 96%
A0A1X0NNJ4 Trypanosomatidae 79% 100%
A0A422MQN2 Trypanosoma rangeli 74% 100%
A4H7Q7 Leishmania braziliensis 94% 100%
A4HW46 Leishmania infantum 100% 100%
C9ZSX5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 73% 100%
E9APU9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 98% 100%
Q4QFN1 Leishmania major 99% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS