PI3-kinase family, ras-binding domain/Phosphoinositide 3-kinase C2/Phosphoinositide 3-kinase family, accessory domain (PIK domain)/Phosphatidylinositol 3- and 4-kinase, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

phosphatidylinositol 3-kinase 2, putative

Species:

Leishmania donovani

UniProt:

A0A3S7WSQ8_LEIDO

TriTrypDb:

LdBPK_140020.1 , LdCL_140005100 , LDHU3_14.0040

Length:

1047

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A0A3S7WSQ8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WSQ8

Function

Biological processes
Term	Name	Level	Count
GO:0006629	lipid metabolic process	3	6
GO:0006644	phospholipid metabolic process	4	6
GO:0006650	glycerophospholipid metabolic process	5	6
GO:0006661	phosphatidylinositol biosynthetic process	6	6
GO:0006793	phosphorus metabolic process	3	8
GO:0006796	phosphate-containing compound metabolic process	4	8
GO:0007165	signal transduction	2	8
GO:0008152	metabolic process	1	8
GO:0008610	lipid biosynthetic process	4	6
GO:0008654	phospholipid biosynthetic process	5	6
GO:0009058	biosynthetic process	2	6
GO:0009987	cellular process	1	8
GO:0016310	phosphorylation	5	8
GO:0019637	organophosphate metabolic process	3	6
GO:0035556	intracellular signal transduction	3	8
GO:0044237	cellular metabolic process	2	8
GO:0044238	primary metabolic process	2	6
GO:0044249	cellular biosynthetic process	3	6
GO:0044255	cellular lipid metabolic process	3	6
GO:0045017	glycerolipid biosynthetic process	4	6
GO:0046474	glycerophospholipid biosynthetic process	5	6
GO:0046486	glycerolipid metabolic process	4	6
GO:0046488	phosphatidylinositol metabolic process	6	6
GO:0046854	phosphatidylinositol phosphate biosynthetic process	7	6
GO:0048015	phosphatidylinositol-mediated signaling	5	8
GO:0048017	inositol lipid-mediated signaling	4	8
GO:0050789	regulation of biological process	2	8
GO:0050794	regulation of cellular process	3	8
GO:0065007	biological regulation	1	8
GO:0071704	organic substance metabolic process	2	6
GO:0090407	organophosphate biosynthetic process	4	6
GO:1901576	organic substance biosynthetic process	3	6

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	8
GO:0003824	catalytic activity	1	8
GO:0005488	binding	1	8
GO:0005524	ATP binding	5	8
GO:0016301	kinase activity	4	8
GO:0016740	transferase activity	2	8
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	8
GO:0017076	purine nucleotide binding	4	8
GO:0030554	adenyl nucleotide binding	5	8
GO:0032553	ribonucleotide binding	3	8
GO:0032555	purine ribonucleotide binding	4	8
GO:0032559	adenyl ribonucleotide binding	5	8
GO:0035639	purine ribonucleoside triphosphate binding	4	8
GO:0036094	small molecule binding	2	8
GO:0043167	ion binding	2	8
GO:0043168	anion binding	3	8
GO:0097159	organic cyclic compound binding	2	8
GO:0097367	carbohydrate derivative binding	2	8
GO:1901265	nucleoside phosphate binding	3	8
GO:1901363	heterocyclic compound binding	2	8
GO:0016303	1-phosphatidylinositol-3-kinase activity	6	2
GO:0016773	phosphotransferase activity, alcohol group as acceptor	4	2
GO:0035004	phosphatidylinositol 3-kinase activity	5	2
GO:0052742	phosphatidylinositol kinase activity	5	2
GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity	6	1
GO:0052812	phosphatidylinositol-3,4-bisphosphate 5-kinase activity	6	1
GO:0052813	phosphatidylinositol bisphosphate kinase activity	5	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	154	158	PF00656	0.347
CLV_C14_Caspase3-7	277	281	PF00656	0.374
CLV_C14_Caspase3-7	601	605	PF00656	0.226
CLV_C14_Caspase3-7	807	811	PF00656	0.186
CLV_NRD_NRD_1	178	180	PF00675	0.461
CLV_NRD_NRD_1	43	45	PF00675	0.505
CLV_NRD_NRD_1	500	502	PF00675	0.504
CLV_NRD_NRD_1	507	509	PF00675	0.484
CLV_NRD_NRD_1	589	591	PF00675	0.415
CLV_NRD_NRD_1	655	657	PF00675	0.401
CLV_NRD_NRD_1	85	87	PF00675	0.530
CLV_NRD_NRD_1	851	853	PF00675	0.404
CLV_NRD_NRD_1	976	978	PF00675	0.172
CLV_NRD_NRD_1	98	100	PF00675	0.388
CLV_PCSK_KEX2_1	177	179	PF00082	0.475
CLV_PCSK_KEX2_1	243	245	PF00082	0.390
CLV_PCSK_KEX2_1	43	45	PF00082	0.507
CLV_PCSK_KEX2_1	500	502	PF00082	0.492
CLV_PCSK_KEX2_1	507	509	PF00082	0.497
CLV_PCSK_KEX2_1	533	535	PF00082	0.386
CLV_PCSK_KEX2_1	589	591	PF00082	0.468
CLV_PCSK_KEX2_1	655	657	PF00082	0.386
CLV_PCSK_KEX2_1	694	696	PF00082	0.408
CLV_PCSK_KEX2_1	85	87	PF00082	0.557
CLV_PCSK_KEX2_1	851	853	PF00082	0.415
CLV_PCSK_KEX2_1	937	939	PF00082	0.186
CLV_PCSK_KEX2_1	976	978	PF00082	0.172
CLV_PCSK_KEX2_1	98	100	PF00082	0.400
CLV_PCSK_PC1ET2_1	243	245	PF00082	0.390
CLV_PCSK_PC1ET2_1	500	502	PF00082	0.481
CLV_PCSK_PC1ET2_1	533	535	PF00082	0.386
CLV_PCSK_PC1ET2_1	694	696	PF00082	0.475
CLV_PCSK_PC1ET2_1	937	939	PF00082	0.186
CLV_PCSK_PC7_1	173	179	PF00082	0.463
CLV_PCSK_PC7_1	651	657	PF00082	0.386
CLV_PCSK_SKI1_1	1007	1011	PF00082	0.225
CLV_PCSK_SKI1_1	1035	1039	PF00082	0.251
CLV_PCSK_SKI1_1	122	126	PF00082	0.561
CLV_PCSK_SKI1_1	254	258	PF00082	0.518
CLV_PCSK_SKI1_1	31	35	PF00082	0.657
CLV_PCSK_SKI1_1	385	389	PF00082	0.372
CLV_PCSK_SKI1_1	405	409	PF00082	0.340
CLV_PCSK_SKI1_1	489	493	PF00082	0.559
CLV_PCSK_SKI1_1	530	534	PF00082	0.386
CLV_PCSK_SKI1_1	549	553	PF00082	0.401
CLV_PCSK_SKI1_1	556	560	PF00082	0.391
CLV_PCSK_SKI1_1	651	655	PF00082	0.386
CLV_PCSK_SKI1_1	677	681	PF00082	0.415
CLV_PCSK_SKI1_1	714	718	PF00082	0.447
DEG_APCC_DBOX_1	42	50	PF00400	0.306
DEG_APCC_DBOX_1	731	739	PF00400	0.228
DEG_APCC_DBOX_1	796	804	PF00400	0.186
DEG_SPOP_SBC_1	394	398	PF00917	0.240
DOC_ANK_TNKS_1	461	468	PF00023	0.268
DOC_CKS1_1	944	949	PF01111	0.386
DOC_CYCLIN_RxL_1	382	392	PF00134	0.201
DOC_CYCLIN_RxL_1	54	65	PF00134	0.319
DOC_CYCLIN_RxL_1	645	657	PF00134	0.186
DOC_MAPK_gen_1	243	251	PF00069	0.190
DOC_MAPK_gen_1	460	468	PF00069	0.325
DOC_MAPK_gen_1	768	776	PF00069	0.214
DOC_MAPK_MEF2A_6	139	146	PF00069	0.358
DOC_MAPK_MEF2A_6	206	215	PF00069	0.221
DOC_MAPK_MEF2A_6	243	251	PF00069	0.268
DOC_MAPK_MEF2A_6	768	776	PF00069	0.230
DOC_MAPK_MEF2A_6	797	805	PF00069	0.199
DOC_MAPK_MEF2A_6	814	822	PF00069	0.203
DOC_MAPK_NFAT4_5	139	147	PF00069	0.363
DOC_MAPK_NFAT4_5	244	252	PF00069	0.190
DOC_PP1_RVXF_1	363	369	PF00149	0.240
DOC_PP1_RVXF_1	386	392	PF00149	0.275
DOC_PP1_RVXF_1	487	494	PF00149	0.328
DOC_PP1_RVXF_1	547	554	PF00149	0.201
DOC_PP1_RVXF_1	55	62	PF00149	0.305
DOC_PP1_RVXF_1	735	741	PF00149	0.229
DOC_PP2B_LxvP_1	7	10	PF13499	0.369
DOC_PP2B_PxIxI_1	210	216	PF00149	0.190
DOC_PP4_FxxP_1	132	135	PF00568	0.267
DOC_PP4_FxxP_1	259	262	PF00568	0.331
DOC_PP4_FxxP_1	487	490	PF00568	0.269
DOC_SPAK_OSR1_1	15	19	PF12202	0.358
DOC_USP7_MATH_1	111	115	PF00917	0.293
DOC_USP7_MATH_1	124	128	PF00917	0.246
DOC_USP7_MATH_1	274	278	PF00917	0.545
DOC_USP7_MATH_1	279	283	PF00917	0.491
DOC_USP7_MATH_1	356	360	PF00917	0.215
DOC_USP7_MATH_1	516	520	PF00917	0.387
DOC_USP7_UBL2_3	564	568	PF12436	0.226
DOC_USP7_UBL2_3	725	729	PF12436	0.252
DOC_USP7_UBL2_3	933	937	PF12436	0.386
DOC_WW_Pin1_4	207	212	PF00397	0.190
DOC_WW_Pin1_4	272	277	PF00397	0.490
DOC_WW_Pin1_4	589	594	PF00397	0.268
DOC_WW_Pin1_4	693	698	PF00397	0.268
DOC_WW_Pin1_4	943	948	PF00397	0.391
DOC_WW_Pin1_4	955	960	PF00397	0.405
LIG_14-3-3_CanoR_1	173	181	PF00244	0.410
LIG_14-3-3_CanoR_1	191	200	PF00244	0.214
LIG_14-3-3_CanoR_1	31	38	PF00244	0.449
LIG_14-3-3_CanoR_1	405	413	PF00244	0.229
LIG_14-3-3_CanoR_1	44	50	PF00244	0.246
LIG_14-3-3_CanoR_1	655	659	PF00244	0.228
LIG_14-3-3_CanoR_1	732	736	PF00244	0.288
LIG_14-3-3_CanoR_1	743	747	PF00244	0.174
LIG_14-3-3_CanoR_1	85	94	PF00244	0.399
LIG_14-3-3_CanoR_1	976	986	PF00244	0.468
LIG_Actin_WH2_2	519	535	PF00022	0.238
LIG_Actin_WH2_2	993	1009	PF00022	0.434
LIG_BIR_II_1	1	5	PF00653	0.386
LIG_BIR_III_4	1029	1033	PF00653	0.497
LIG_BRCT_BRCA1_1	325	329	PF00533	0.306
LIG_BRCT_BRCA1_1	428	432	PF00533	0.229
LIG_BRCT_BRCA1_1	766	770	PF00533	0.286
LIG_BRCT_BRCA1_1	957	961	PF00533	0.415
LIG_Clathr_ClatBox_1	576	580	PF01394	0.215
LIG_Clathr_ClatBox_1	918	922	PF01394	0.386
LIG_deltaCOP1_diTrp_1	108	112	PF00928	0.242
LIG_eIF4E_1	226	232	PF01652	0.186
LIG_eIF4E_1	582	588	PF01652	0.201
LIG_eIF4E_1	707	713	PF01652	0.201
LIG_FHA_1	1006	1012	PF00498	0.446
LIG_FHA_1	123	129	PF00498	0.258
LIG_FHA_1	208	214	PF00498	0.215
LIG_FHA_1	284	290	PF00498	0.377
LIG_FHA_1	293	299	PF00498	0.334
LIG_FHA_1	373	379	PF00498	0.213
LIG_FHA_1	396	402	PF00498	0.276
LIG_FHA_1	477	483	PF00498	0.317
LIG_FHA_1	743	749	PF00498	0.207
LIG_FHA_1	800	806	PF00498	0.186
LIG_FHA_1	895	901	PF00498	0.227
LIG_FHA_2	1013	1019	PF00498	0.486
LIG_FHA_2	182	188	PF00498	0.309
LIG_FHA_2	30	36	PF00498	0.342
LIG_FHA_2	406	412	PF00498	0.240
LIG_FHA_2	66	72	PF00498	0.272
LIG_FHA_2	678	684	PF00498	0.215
LIG_FHA_2	848	854	PF00498	0.226
LIG_FHA_2	997	1003	PF00498	0.520
LIG_IRF3_LxIS_1	306	312	PF10401	0.345
LIG_LIR_Apic_2	257	262	PF02991	0.335
LIG_LIR_Gen_1	1040	1046	PF02991	0.481
LIG_LIR_Gen_1	199	205	PF02991	0.221
LIG_LIR_Gen_1	326	337	PF02991	0.250
LIG_LIR_Gen_1	604	612	PF02991	0.201
LIG_LIR_Gen_1	784	794	PF02991	0.232
LIG_LIR_LC3C_4	246	251	PF02991	0.190
LIG_LIR_Nem_3	1020	1026	PF02991	0.492
LIG_LIR_Nem_3	1040	1044	PF02991	0.465
LIG_LIR_Nem_3	108	112	PF02991	0.262
LIG_LIR_Nem_3	325	331	PF02991	0.286
LIG_LIR_Nem_3	481	487	PF02991	0.231
LIG_LIR_Nem_3	604	610	PF02991	0.226
LIG_LIR_Nem_3	783	789	PF02991	0.274
LIG_LIR_Nem_3	922	926	PF02991	0.386
LIG_LIR_Nem_3	958	964	PF02991	0.386
LIG_MLH1_MIPbox_1	325	329	PF16413	0.233
LIG_MLH1_MIPbox_1	428	432	PF16413	0.215
LIG_PCNA_APIM_2	649	655	PF02747	0.186
LIG_PCNA_yPIPBox_3	655	668	PF02747	0.268
LIG_Pex14_1	575	579	PF04695	0.186
LIG_Pex14_1	868	872	PF04695	0.186
LIG_Pex14_2	480	484	PF04695	0.261
LIG_Pex14_2	740	744	PF04695	0.301
LIG_Pex14_2	786	790	PF04695	0.196
LIG_Pex14_2	919	923	PF04695	0.386
LIG_Pex14_2	926	930	PF04695	0.386
LIG_PTB_Apo_2	230	237	PF02174	0.172
LIG_PTB_Phospho_1	230	236	PF10480	0.172
LIG_SH2_CRK	1023	1027	PF00017	0.512
LIG_SH2_CRK	234	238	PF00017	0.190
LIG_SH2_CRK	538	542	PF00017	0.268
LIG_SH2_CRK	646	650	PF00017	0.226
LIG_SH2_CRK	825	829	PF00017	0.186
LIG_SH2_CRK	972	976	PF00017	0.426
LIG_SH2_GRB2like	105	108	PF00017	0.242
LIG_SH2_NCK_1	893	897	PF00017	0.224
LIG_SH2_PTP2	1041	1044	PF00017	0.430
LIG_SH2_SRC	1041	1044	PF00017	0.430
LIG_SH2_SRC	166	169	PF00017	0.266
LIG_SH2_SRC	224	227	PF00017	0.186
LIG_SH2_SRC	949	952	PF00017	0.468
LIG_SH2_STAP1	443	447	PF00017	0.268
LIG_SH2_STAP1	607	611	PF00017	0.240
LIG_SH2_STAP1	646	650	PF00017	0.268
LIG_SH2_STAT3	226	229	PF00017	0.268
LIG_SH2_STAT3	702	705	PF00017	0.199
LIG_SH2_STAT5	1041	1044	PF00017	0.430
LIG_SH2_STAT5	105	108	PF00017	0.242
LIG_SH2_STAT5	166	169	PF00017	0.270
LIG_SH2_STAT5	224	227	PF00017	0.201
LIG_SH2_STAT5	236	239	PF00017	0.186
LIG_SH2_STAT5	328	331	PF00017	0.227
LIG_SH2_STAT5	336	339	PF00017	0.265
LIG_SH2_STAT5	455	458	PF00017	0.281
LIG_SH2_STAT5	520	523	PF00017	0.303
LIG_SH2_STAT5	619	622	PF00017	0.232
LIG_SH2_STAT5	667	670	PF00017	0.186
LIG_SH2_STAT5	671	674	PF00017	0.186
LIG_SH2_STAT5	702	705	PF00017	0.199
LIG_SH2_STAT5	707	710	PF00017	0.201
LIG_SH2_STAT5	79	82	PF00017	0.206
LIG_SH2_STAT5	893	896	PF00017	0.214
LIG_SH2_STAT5	898	901	PF00017	0.214
LIG_SH2_STAT5	949	952	PF00017	0.451
LIG_SH2_STAT5	963	966	PF00017	0.390
LIG_SH3_2	117	122	PF14604	0.304
LIG_SH3_2	266	271	PF14604	0.275
LIG_SH3_3	114	120	PF00018	0.296
LIG_SH3_3	247	253	PF00018	0.309
LIG_SH3_3	263	269	PF00018	0.268
LIG_SH3_3	479	485	PF00018	0.254
LIG_SH3_3	488	494	PF00018	0.269
LIG_SH3_3	735	741	PF00018	0.322
LIG_SH3_3	953	959	PF00018	0.331
LIG_SUMO_SIM_anti_2	1008	1013	PF11976	0.436
LIG_SUMO_SIM_anti_2	246	252	PF11976	0.301
LIG_SUMO_SIM_anti_2	598	604	PF11976	0.186
LIG_SUMO_SIM_par_1	986	992	PF11976	0.386
LIG_TRAF2_1	1015	1018	PF00917	0.444
LIG_TRAF2_1	408	411	PF00917	0.201
LIG_TRAF2_1	415	418	PF00917	0.201
LIG_TYR_ITIM	232	237	PF00017	0.220
LIG_TYR_ITIM	536	541	PF00017	0.330
LIG_TYR_ITIM	823	828	PF00017	0.236
LIG_UBA3_1	632	640	PF00899	0.318
LIG_UBA3_1	688	694	PF00899	0.279
LIG_UBA3_1	805	814	PF00899	0.214
MOD_CDC14_SPxK_1	696	699	PF00782	0.381
MOD_CDK_SPxK_1	693	699	PF00069	0.330
MOD_CDK_SPxxK_3	955	962	PF00069	0.330
MOD_CK1_1	169	175	PF00069	0.542
MOD_CK1_1	267	273	PF00069	0.401
MOD_CK1_1	282	288	PF00069	0.565
MOD_CK1_1	296	302	PF00069	0.483
MOD_CK1_1	50	56	PF00069	0.473
MOD_CK1_1	657	663	PF00069	0.224
MOD_CK2_1	1012	1018	PF00069	0.307
MOD_CK2_1	115	121	PF00069	0.445
MOD_CK2_1	193	199	PF00069	0.348
MOD_CK2_1	282	288	PF00069	0.615
MOD_CK2_1	29	35	PF00069	0.438
MOD_CK2_1	405	411	PF00069	0.262
MOD_CK2_1	45	51	PF00069	0.282
MOD_CK2_1	621	627	PF00069	0.214
MOD_CK2_1	65	71	PF00069	0.244
MOD_CK2_1	677	683	PF00069	0.220
MOD_CK2_1	826	832	PF00069	0.270
MOD_CK2_1	847	853	PF00069	0.330
MOD_CK2_1	87	93	PF00069	0.306
MOD_GlcNHglycan	168	171	PF01048	0.535
MOD_GlcNHglycan	195	198	PF01048	0.220
MOD_GlcNHglycan	311	314	PF01048	0.505
MOD_GlcNHglycan	494	497	PF01048	0.424
MOD_GlcNHglycan	570	573	PF01048	0.361
MOD_GlcNHglycan	646	649	PF01048	0.255
MOD_GlcNHglycan	791	794	PF01048	0.330
MOD_GlcNHglycan	815	818	PF01048	0.404
MOD_GlcNHglycan	979	982	PF01048	0.272
MOD_GSK3_1	111	118	PF00069	0.395
MOD_GSK3_1	152	159	PF00069	0.539
MOD_GSK3_1	169	176	PF00069	0.421
MOD_GSK3_1	27	34	PF00069	0.617
MOD_GSK3_1	279	286	PF00069	0.535
MOD_GSK3_1	292	299	PF00069	0.245
MOD_GSK3_1	370	377	PF00069	0.347
MOD_GSK3_1	389	396	PF00069	0.172
MOD_GSK3_1	472	479	PF00069	0.457
MOD_GSK3_1	543	550	PF00069	0.303
MOD_N-GLC_1	1012	1017	PF02516	0.457
MOD_N-GLC_1	677	682	PF02516	0.214
MOD_N-GLC_1	847	852	PF02516	0.214
MOD_N-GLC_1	87	92	PF02516	0.289
MOD_N-GLC_2	476	478	PF02516	0.352
MOD_NEK2_1	192	197	PF00069	0.357
MOD_NEK2_1	29	34	PF00069	0.549
MOD_NEK2_1	309	314	PF00069	0.535
MOD_NEK2_1	389	394	PF00069	0.225
MOD_NEK2_1	432	437	PF00069	0.270
MOD_NEK2_1	654	659	PF00069	0.219
MOD_NEK2_1	731	736	PF00069	0.304
MOD_NEK2_1	808	813	PF00069	0.214
MOD_NEK2_1	886	891	PF00069	0.273
MOD_NEK2_1	988	993	PF00069	0.280
MOD_NEK2_2	111	116	PF00069	0.316
MOD_NEK2_2	158	163	PF00069	0.324
MOD_PIKK_1	225	231	PF00454	0.290
MOD_PIKK_1	435	441	PF00454	0.316
MOD_PKA_1	937	943	PF00069	0.214
MOD_PKA_1	976	982	PF00069	0.246
MOD_PKA_2	172	178	PF00069	0.354
MOD_PKA_2	190	196	PF00069	0.219
MOD_PKA_2	264	270	PF00069	0.424
MOD_PKA_2	321	327	PF00069	0.440
MOD_PKA_2	654	660	PF00069	0.236
MOD_PKA_2	731	737	PF00069	0.337
MOD_PKA_2	742	748	PF00069	0.203
MOD_PKA_2	937	943	PF00069	0.214
MOD_PKA_2	976	982	PF00069	0.322
MOD_Plk_1	254	260	PF00069	0.357
MOD_Plk_1	322	328	PF00069	0.476
MOD_Plk_1	547	553	PF00069	0.282
MOD_Plk_1	677	683	PF00069	0.215
MOD_Plk_2-3	199	205	PF00069	0.220
MOD_Plk_2-3	621	627	PF00069	0.330
MOD_Plk_2-3	996	1002	PF00069	0.407
MOD_Plk_4	254	260	PF00069	0.323
MOD_Plk_4	323	329	PF00069	0.418
MOD_Plk_4	426	432	PF00069	0.425
MOD_Plk_4	516	522	PF00069	0.386
MOD_Plk_4	547	553	PF00069	0.255
MOD_Plk_4	808	814	PF00069	0.239
MOD_Plk_4	894	900	PF00069	0.214
MOD_Plk_4	914	920	PF00069	0.115
MOD_ProDKin_1	207	213	PF00069	0.220
MOD_ProDKin_1	272	278	PF00069	0.640
MOD_ProDKin_1	589	595	PF00069	0.330
MOD_ProDKin_1	693	699	PF00069	0.330
MOD_ProDKin_1	943	949	PF00069	0.221
MOD_ProDKin_1	955	961	PF00069	0.241
MOD_SUMO_for_1	316	319	PF00179	0.332
MOD_SUMO_for_1	639	642	PF00179	0.214
MOD_SUMO_for_1	936	939	PF00179	0.227
MOD_SUMO_rev_2	102	112	PF00179	0.353
MOD_SUMO_rev_2	246	256	PF00179	0.255
MOD_SUMO_rev_2	381	389	PF00179	0.210
MOD_SUMO_rev_2	545	551	PF00179	0.253
MOD_SUMO_rev_2	758	765	PF00179	0.400
TRG_DiLeu_BaEn_1	583	588	PF01217	0.236
TRG_DiLeu_BaEn_1	683	688	PF01217	0.214
TRG_DiLeu_BaEn_2	938	944	PF01217	0.214
TRG_DiLeu_BaLyEn_6	208	213	PF01217	0.405
TRG_DiLeu_BaLyEn_6	227	232	PF01217	0.155
TRG_DiLeu_BaLyEn_6	54	59	PF01217	0.315
TRG_ENDOCYTIC_2	1023	1026	PF00928	0.376
TRG_ENDOCYTIC_2	1041	1044	PF00928	0.319
TRG_ENDOCYTIC_2	234	237	PF00928	0.220
TRG_ENDOCYTIC_2	328	331	PF00928	0.313
TRG_ENDOCYTIC_2	538	541	PF00928	0.330
TRG_ENDOCYTIC_2	555	558	PF00928	0.305
TRG_ENDOCYTIC_2	607	610	PF00928	0.270
TRG_ENDOCYTIC_2	646	649	PF00928	0.270
TRG_ENDOCYTIC_2	825	828	PF00928	0.227
TRG_ENDOCYTIC_2	972	975	PF00928	0.279
TRG_ER_diArg_1	177	179	PF00400	0.514
TRG_ER_diArg_1	3	6	PF00400	0.476
TRG_ER_diArg_1	588	590	PF00400	0.255
TRG_ER_diArg_1	654	656	PF00400	0.236
TRG_ER_diArg_1	85	87	PF00400	0.443
TRG_ER_diArg_1	97	99	PF00400	0.242
TRG_ER_diArg_1	975	977	PF00400	0.195
TRG_NES_CRM1_1	1001	1016	PF08389	0.318
TRG_NES_CRM1_1	527	539	PF08389	0.255
TRG_NES_CRM1_1	627	642	PF08389	0.236
TRG_NES_CRM1_1	794	807	PF08389	0.214
TRG_Pf-PMV_PEXEL_1	1035	1040	PF00026	0.278
TRG_Pf-PMV_PEXEL_1	126	130	PF00026	0.362
TRG_Pf-PMV_PEXEL_1	31	35	PF00026	0.429
TRG_Pf-PMV_PEXEL_1	36	40	PF00026	0.369
TRG_Pf-PMV_PEXEL_1	534	539	PF00026	0.214

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0G2K344	Rattus norvegicus	33%	98%
A0A0N1I4K0	Leptomonas seymouri	74%	100%
A0A1X0NPD0	Trypanosomatidae	55%	99%
A0A3R7MRK8	Trypanosoma rangeli	51%	99%
A4HVU4	Leishmania infantum	100%	100%
E9APJ6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%
O00329	Homo sapiens	33%	100%
O02697	Sus scrofa	33%	95%
O35904	Mus musculus	34%	100%
P0C5E7	Caenorhabditis briggsae	28%	90%
P32871	Bos taurus	33%	98%
P42336	Homo sapiens	33%	98%
P42337	Mus musculus	33%	98%
P42338	Homo sapiens	33%	98%
P48736	Homo sapiens	34%	95%
Q8BTI9	Mus musculus	33%	98%
Q94125	Caenorhabditis elegans	29%	89%
Q9JHG7	Mus musculus	34%	95%
Q9Z1L0	Rattus norvegicus	33%	98%
V5AXQ0	Trypanosoma cruzi	52%	99%