Bifunctional helicase and thymine dioxygenase JBP2

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

J Biosynthesis Protein 2

Species:

Leishmania donovani

UniProt:

A0A3S7WSQ7_LEIDO

TriTrypDb:

LdBPK_140040.1 , LdCL_140005300 , LDHU3_14.0060

Length:

1022

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	12
GO:0043226	organelle	2	12
GO:0043227	membrane-bounded organelle	3	12
GO:0043229	intracellular organelle	3	12
GO:0043231	intracellular membrane-bounded organelle	4	12
GO:0110165	cellular anatomical entity	1	12

Expansion

Sequence features

A0A3S7WSQ7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WSQ7

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	12
GO:0006259	DNA metabolic process	4	12
GO:0006304	DNA modification	5	12
GO:0006725	cellular aromatic compound metabolic process	3	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0008152	metabolic process	1	12
GO:0009987	cellular process	1	12
GO:0034641	cellular nitrogen compound metabolic process	3	12
GO:0043170	macromolecule metabolic process	3	12
GO:0043412	macromolecule modification	4	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0044260	obsolete cellular macromolecule metabolic process	3	12
GO:0046483	heterocycle metabolic process	3	12
GO:0070580	base J metabolic process	6	12
GO:0071704	organic substance metabolic process	2	12
GO:0090304	nucleic acid metabolic process	4	12
GO:1901360	organic cyclic compound metabolic process	3	12
GO:0006281	DNA repair	5	1
GO:0006283	transcription-coupled nucleotide-excision repair	7	1
GO:0006289	nucleotide-excision repair	6	1
GO:0006950	response to stress	2	1
GO:0006974	DNA damage response	4	1
GO:0033554	cellular response to stress	3	1
GO:0050896	response to stimulus	1	1
GO:0051716	cellular response to stimulus	2	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003676	nucleic acid binding	3	12
GO:0003677	DNA binding	4	12
GO:0003824	catalytic activity	1	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0008094	ATP-dependent activity, acting on DNA	2	12
GO:0016491	oxidoreductase activity	2	12
GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	3	12
GO:0016706	2-oxoglutarate-dependent dioxygenase activity	4	12
GO:0017076	purine nucleotide binding	4	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0043169	cation binding	3	12
GO:0046872	metal ion binding	4	12
GO:0050341	thymine dioxygenase activity	5	12
GO:0051213	dioxygenase activity	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140097	catalytic activity, acting on DNA	3	12
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:0140658	ATP-dependent chromatin remodeler activity	3	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12
GO:0003678	DNA helicase activity	3	3
GO:0004386	helicase activity	2	4
GO:0005506	iron ion binding	6	1
GO:0008198	ferrous iron binding	7	1
GO:0016462	pyrophosphatase activity	5	3
GO:0016787	hydrolase activity	2	4
GO:0016817	hydrolase activity, acting on acid anhydrides	3	3
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	3
GO:0016887	ATP hydrolysis activity	7	3
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	3
GO:0046914	transition metal ion binding	5	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	176	180	PF00656	0.612
CLV_C14_Caspase3-7	807	811	PF00656	0.578
CLV_NRD_NRD_1	279	281	PF00675	0.309
CLV_NRD_NRD_1	423	425	PF00675	0.504
CLV_NRD_NRD_1	592	594	PF00675	0.338
CLV_NRD_NRD_1	831	833	PF00675	0.338
CLV_NRD_NRD_1	873	875	PF00675	0.278
CLV_NRD_NRD_1	928	930	PF00675	0.276
CLV_NRD_NRD_1	931	933	PF00675	0.439
CLV_NRD_NRD_1	954	956	PF00675	0.391
CLV_NRD_NRD_1	989	991	PF00675	0.448
CLV_PCSK_FUR_1	593	597	PF00082	0.381
CLV_PCSK_FUR_1	871	875	PF00082	0.337
CLV_PCSK_KEX2_1	279	281	PF00082	0.326
CLV_PCSK_KEX2_1	367	369	PF00082	0.325
CLV_PCSK_KEX2_1	423	425	PF00082	0.501
CLV_PCSK_KEX2_1	592	594	PF00082	0.362
CLV_PCSK_KEX2_1	595	597	PF00082	0.362
CLV_PCSK_KEX2_1	662	664	PF00082	0.362
CLV_PCSK_KEX2_1	871	873	PF00082	0.280
CLV_PCSK_KEX2_1	928	930	PF00082	0.287
CLV_PCSK_KEX2_1	989	991	PF00082	0.438
CLV_PCSK_PC1ET2_1	367	369	PF00082	0.325
CLV_PCSK_PC1ET2_1	595	597	PF00082	0.325
CLV_PCSK_PC1ET2_1	662	664	PF00082	0.362
CLV_PCSK_SKI1_1	1006	1010	PF00082	0.546
CLV_PCSK_SKI1_1	36	40	PF00082	0.648
CLV_PCSK_SKI1_1	367	371	PF00082	0.344
CLV_PCSK_SKI1_1	429	433	PF00082	0.523
CLV_PCSK_SKI1_1	592	596	PF00082	0.295
CLV_PCSK_SKI1_1	629	633	PF00082	0.297
CLV_PCSK_SKI1_1	851	855	PF00082	0.287
CLV_PCSK_SKI1_1	933	937	PF00082	0.470
CLV_PCSK_SKI1_1	947	951	PF00082	0.396
CLV_PCSK_SKI1_1	956	960	PF00082	0.357
CLV_PCSK_SKI1_1	961	965	PF00082	0.340
CLV_PCSK_SKI1_1	970	974	PF00082	0.446
DEG_APCC_DBOX_1	345	353	PF00400	0.487
DEG_APCC_DBOX_1	423	431	PF00400	0.575
DEG_APCC_DBOX_1	624	632	PF00400	0.572
DEG_Nend_UBRbox_4	1	3	PF02207	0.479
DEG_ODPH_VHL_1	302	314	PF01847	0.581
DEG_ODPH_VHL_1	467	479	PF01847	0.505
DEG_SIAH_1	58	66	PF03145	0.401
DOC_CKS1_1	520	525	PF01111	0.537
DOC_CYCLIN_RxL_1	33	43	PF00134	0.670
DOC_CYCLIN_RxL_1	44	53	PF00134	0.369
DOC_CYCLIN_yClb5_NLxxxL_5	625	632	PF00134	0.581
DOC_CYCLIN_yCln2_LP_2	38	44	PF00134	0.516
DOC_MAPK_DCC_7	462	472	PF00069	0.523
DOC_MAPK_gen_1	367	377	PF00069	0.564
DOC_MAPK_gen_1	423	432	PF00069	0.579
DOC_MAPK_gen_1	573	581	PF00069	0.538
DOC_MAPK_gen_1	592	603	PF00069	0.399
DOC_MAPK_gen_1	623	632	PF00069	0.563
DOC_MAPK_gen_1	818	827	PF00069	0.533
DOC_MAPK_gen_1	832	839	PF00069	0.443
DOC_MAPK_gen_1	928	937	PF00069	0.607
DOC_MAPK_HePTP_8	815	827	PF00069	0.449
DOC_MAPK_MEF2A_6	498	507	PF00069	0.476
DOC_MAPK_MEF2A_6	595	603	PF00069	0.518
DOC_MAPK_MEF2A_6	623	632	PF00069	0.581
DOC_MAPK_MEF2A_6	818	827	PF00069	0.501
DOC_MAPK_MEF2A_6	883	890	PF00069	0.508
DOC_MAPK_NFAT4_5	883	891	PF00069	0.553
DOC_MAPK_RevD_3	819	833	PF00069	0.517
DOC_PP1_RVXF_1	45	52	PF00149	0.560
DOC_PP1_RVXF_1	644	651	PF00149	0.487
DOC_PP1_RVXF_1	833	840	PF00149	0.476
DOC_PP2B_LxvP_1	243	246	PF13499	0.597
DOC_PP2B_LxvP_1	457	460	PF13499	0.418
DOC_USP7_MATH_1	1002	1006	PF00917	0.435
DOC_USP7_MATH_1	129	133	PF00917	0.778
DOC_USP7_MATH_1	180	184	PF00917	0.708
DOC_USP7_MATH_1	313	317	PF00917	0.581
DOC_USP7_MATH_1	450	454	PF00917	0.647
DOC_USP7_MATH_1	784	788	PF00917	0.529
DOC_USP7_MATH_1	96	100	PF00917	0.777
DOC_USP7_UBL2_3	293	297	PF12436	0.581
DOC_USP7_UBL2_3	367	371	PF12436	0.487
DOC_USP7_UBL2_3	79	83	PF12436	0.398
DOC_WW_Pin1_4	519	524	PF00397	0.537
DOC_WW_Pin1_4	595	600	PF00397	0.581
DOC_WW_Pin1_4	632	637	PF00397	0.476
DOC_WW_Pin1_4	67	72	PF00397	0.651
DOC_WW_Pin1_4	73	78	PF00397	0.483
DOC_WW_Pin1_4	89	94	PF00397	0.629
DOC_WW_Pin1_4	98	103	PF00397	0.635
LIG_14-3-3_CanoR_1	122	128	PF00244	0.715
LIG_14-3-3_CanoR_1	17	21	PF00244	0.585
LIG_14-3-3_CanoR_1	4	11	PF00244	0.641
LIG_14-3-3_CanoR_1	403	407	PF00244	0.368
LIG_14-3-3_CanoR_1	441	446	PF00244	0.568
LIG_14-3-3_CanoR_1	462	470	PF00244	0.530
LIG_14-3-3_CanoR_1	783	792	PF00244	0.674
LIG_14-3-3_CanoR_1	851	858	PF00244	0.487
LIG_14-3-3_CanoR_1	932	938	PF00244	0.458
LIG_14-3-3_CanoR_1	939	948	PF00244	0.390
LIG_14-3-3_CanoR_1	989	993	PF00244	0.252
LIG_Actin_WH2_2	362	378	PF00022	0.614
LIG_Actin_WH2_2	614	631	PF00022	0.581
LIG_Actin_WH2_2	728	744	PF00022	0.539
LIG_APCC_ABBA_1	107	112	PF00400	0.671
LIG_APCC_ABBAyCdc20_2	199	205	PF00400	0.529
LIG_APCC_ABBAyCdc20_2	335	341	PF00400	0.487
LIG_APCC_ABBAyCdc20_2	697	703	PF00400	0.562
LIG_BRCT_BRCA1_1	149	153	PF00533	0.708
LIG_BRCT_BRCA1_1	554	558	PF00533	0.487
LIG_BRCT_BRCA1_2	149	155	PF00533	0.717
LIG_Clathr_ClatBox_1	601	605	PF01394	0.454
LIG_deltaCOP1_diTrp_1	694	701	PF00928	0.476
LIG_eIF4E_1	409	415	PF01652	0.395
LIG_EVH1_2	660	664	PF00568	0.517
LIG_FHA_1	253	259	PF00498	0.476
LIG_FHA_1	27	33	PF00498	0.449
LIG_FHA_1	325	331	PF00498	0.476
LIG_FHA_1	390	396	PF00498	0.545
LIG_FHA_1	402	408	PF00498	0.396
LIG_FHA_1	442	448	PF00498	0.512
LIG_FHA_1	491	497	PF00498	0.487
LIG_FHA_1	596	602	PF00498	0.581
LIG_FHA_1	616	622	PF00498	0.345
LIG_FHA_1	792	798	PF00498	0.547
LIG_FHA_1	858	864	PF00498	0.582
LIG_FHA_1	952	958	PF00498	0.445
LIG_FHA_1	996	1002	PF00498	0.461
LIG_FHA_2	166	172	PF00498	0.672
LIG_FHA_2	383	389	PF00498	0.426
LIG_GBD_Chelix_1	406	414	PF00786	0.391
LIG_IRF3_LxIS_1	71	76	PF10401	0.624
LIG_LIR_Apic_2	911	916	PF02991	0.476
LIG_LIR_Gen_1	187	196	PF02991	0.465
LIG_LIR_Gen_1	296	305	PF02991	0.562
LIG_LIR_Gen_1	323	330	PF02991	0.483
LIG_LIR_Gen_1	504	514	PF02991	0.562
LIG_LIR_Gen_1	70	78	PF02991	0.640
LIG_LIR_Gen_1	763	770	PF02991	0.648
LIG_LIR_Gen_1	798	804	PF02991	0.553
LIG_LIR_Gen_1	810	819	PF02991	0.319
LIG_LIR_Gen_1	991	1001	PF02991	0.407
LIG_LIR_Nem_3	142	147	PF02991	0.717
LIG_LIR_Nem_3	187	191	PF02991	0.451
LIG_LIR_Nem_3	192	197	PF02991	0.403
LIG_LIR_Nem_3	24	28	PF02991	0.623
LIG_LIR_Nem_3	296	302	PF02991	0.545
LIG_LIR_Nem_3	323	328	PF02991	0.511
LIG_LIR_Nem_3	504	510	PF02991	0.562
LIG_LIR_Nem_3	642	648	PF02991	0.476
LIG_LIR_Nem_3	70	75	PF02991	0.656
LIG_LIR_Nem_3	713	717	PF02991	0.490
LIG_LIR_Nem_3	798	803	PF02991	0.566
LIG_LIR_Nem_3	810	815	PF02991	0.320
LIG_LIR_Nem_3	936	941	PF02991	0.485
LIG_LIR_Nem_3	991	996	PF02991	0.413
LIG_NRBOX	431	437	PF00104	0.632
LIG_PCNA_yPIPBox_3	367	381	PF02747	0.615
LIG_PCNA_yPIPBox_3	646	659	PF02747	0.517
LIG_PCNA_yPIPBox_3	806	820	PF02747	0.507
LIG_Pex14_1	695	699	PF04695	0.476
LIG_Pex14_2	590	594	PF04695	0.581
LIG_Pex14_2	910	914	PF04695	0.537
LIG_PTB_Apo_2	15	22	PF02174	0.569
LIG_PTB_Apo_2	353	360	PF02174	0.562
LIG_PTB_Apo_2	580	587	PF02174	0.487
LIG_PTB_Phospho_1	15	21	PF10480	0.644
LIG_PTB_Phospho_1	580	586	PF10480	0.487
LIG_SH2_CRK	261	265	PF00017	0.476
LIG_SH2_CRK	299	303	PF00017	0.566
LIG_SH2_CRK	645	649	PF00017	0.487
LIG_SH2_CRK	683	687	PF00017	0.581
LIG_SH2_CRK	938	942	PF00017	0.485
LIG_SH2_NCK_1	11	15	PF00017	0.557
LIG_SH2_NCK_1	5	9	PF00017	0.636
LIG_SH2_PTP2	800	803	PF00017	0.503
LIG_SH2_SRC	1014	1017	PF00017	0.551
LIG_SH2_SRC	217	220	PF00017	0.516
LIG_SH2_STAP1	299	303	PF00017	0.517
LIG_SH2_STAP1	727	731	PF00017	0.556
LIG_SH2_STAT3	1012	1015	PF00017	0.545
LIG_SH2_STAT3	54	57	PF00017	0.549
LIG_SH2_STAT3	565	568	PF00017	0.476
LIG_SH2_STAT5	188	191	PF00017	0.439
LIG_SH2_STAT5	217	220	PF00017	0.444
LIG_SH2_STAT5	263	266	PF00017	0.476
LIG_SH2_STAT5	409	412	PF00017	0.409
LIG_SH2_STAT5	44	47	PF00017	0.486
LIG_SH2_STAT5	5	8	PF00017	0.488
LIG_SH2_STAT5	55	58	PF00017	0.441
LIG_SH2_STAT5	586	589	PF00017	0.484
LIG_SH2_STAT5	691	694	PF00017	0.487
LIG_SH2_STAT5	714	717	PF00017	0.552
LIG_SH2_STAT5	758	761	PF00017	0.515
LIG_SH2_STAT5	800	803	PF00017	0.557
LIG_SH2_STAT5	842	845	PF00017	0.496
LIG_SH3_1	90	96	PF00018	0.619
LIG_SH3_3	213	219	PF00018	0.528
LIG_SH3_3	230	236	PF00018	0.522
LIG_SH3_3	309	315	PF00018	0.538
LIG_SH3_3	391	397	PF00018	0.520
LIG_SH3_3	53	59	PF00018	0.554
LIG_SH3_3	655	661	PF00018	0.517
LIG_SH3_3	90	96	PF00018	0.619
LIG_SH3_5	710	714	PF00018	0.487
LIG_Sin3_3	230	237	PF02671	0.545
LIG_SUMO_SIM_anti_2	517	522	PF11976	0.476
LIG_SUMO_SIM_anti_2	884	892	PF11976	0.550
LIG_SUMO_SIM_par_1	499	504	PF11976	0.520
LIG_SUMO_SIM_par_1	517	522	PF11976	0.538
LIG_SUMO_SIM_par_1	598	606	PF11976	0.505
LIG_SUMO_SIM_par_1	884	892	PF11976	0.545
LIG_TRAF2_1	157	160	PF00917	0.753
LIG_TRAF2_1	173	176	PF00917	0.586
LIG_TRAF2_1	875	878	PF00917	0.553
LIG_TYR_ITSM	934	941	PF00017	0.501
LIG_UBA3_1	291	297	PF00899	0.415
LIG_UBA3_1	518	524	PF00899	0.413
LIG_UBA3_1	885	893	PF00899	0.398
LIG_WRC_WIRS_1	181	186	PF05994	0.690
LIG_WRC_WIRS_1	858	863	PF05994	0.396
MOD_CDC14_SPxK_1	76	79	PF00782	0.607
MOD_CDK_SPK_2	519	524	PF00069	0.413
MOD_CDK_SPxK_1	73	79	PF00069	0.611
MOD_CK1_1	127	133	PF00069	0.766
MOD_CK1_1	142	148	PF00069	0.624
MOD_CK1_1	326	332	PF00069	0.328
MOD_CK1_1	765	771	PF00069	0.645
MOD_CK1_1	779	785	PF00069	0.731
MOD_CK2_1	1014	1020	PF00069	0.583
MOD_CK2_1	110	116	PF00069	0.750
MOD_CK2_1	133	139	PF00069	0.799
MOD_CK2_1	170	176	PF00069	0.606
MOD_CK2_1	382	388	PF00069	0.387
MOD_CK2_1	4	10	PF00069	0.505
MOD_CK2_1	414	420	PF00069	0.594
MOD_CK2_1	784	790	PF00069	0.642
MOD_CK2_1	939	945	PF00069	0.407
MOD_GlcNHglycan	131	134	PF01048	0.793
MOD_GlcNHglycan	144	147	PF01048	0.664
MOD_GlcNHglycan	149	152	PF01048	0.489
MOD_GlcNHglycan	346	349	PF01048	0.344
MOD_GlcNHglycan	485	488	PF01048	0.478
MOD_GlcNHglycan	6	9	PF01048	0.629
MOD_GlcNHglycan	632	635	PF01048	0.337
MOD_GlcNHglycan	770	773	PF01048	0.631
MOD_GlcNHglycan	814	818	PF01048	0.377
MOD_GlcNHglycan	941	944	PF01048	0.455
MOD_GSK3_1	1014	1021	PF00069	0.567
MOD_GSK3_1	124	131	PF00069	0.755
MOD_GSK3_1	135	142	PF00069	0.709
MOD_GSK3_1	170	177	PF00069	0.672
MOD_GSK3_1	320	327	PF00069	0.328
MOD_GSK3_1	333	340	PF00069	0.328
MOD_GSK3_1	409	416	PF00069	0.548
MOD_GSK3_1	458	465	PF00069	0.495
MOD_GSK3_1	479	486	PF00069	0.483
MOD_GSK3_1	501	508	PF00069	0.387
MOD_N-GLC_1	441	446	PF02516	0.598
MOD_N-GLC_1	779	784	PF02516	0.751
MOD_NEK2_1	16	21	PF00069	0.585
MOD_NEK2_1	28	33	PF00069	0.641
MOD_NEK2_1	320	325	PF00069	0.328
MOD_NEK2_1	382	387	PF00069	0.371
MOD_NEK2_1	414	419	PF00069	0.592
MOD_NEK2_1	496	501	PF00069	0.327
MOD_NEK2_1	505	510	PF00069	0.338
MOD_NEK2_1	731	736	PF00069	0.606
MOD_NEK2_1	888	893	PF00069	0.328
MOD_NEK2_1	899	904	PF00069	0.328
MOD_NEK2_1	909	914	PF00069	0.315
MOD_NEK2_1	996	1001	PF00069	0.411
MOD_NEK2_2	1014	1019	PF00069	0.552
MOD_NEK2_2	223	228	PF00069	0.585
MOD_NEK2_2	859	864	PF00069	0.449
MOD_PIKK_1	265	271	PF00454	0.350
MOD_PIKK_1	297	303	PF00454	0.440
MOD_PIKK_1	313	319	PF00454	0.449
MOD_PIKK_1	505	511	PF00454	0.398
MOD_PIKK_1	784	790	PF00454	0.667
MOD_PIKK_1	842	848	PF00454	0.348
MOD_PIKK_1	865	871	PF00454	0.449
MOD_PIKK_1	949	955	PF00454	0.426
MOD_PKA_2	121	127	PF00069	0.654
MOD_PKA_2	16	22	PF00069	0.537
MOD_PKA_2	272	278	PF00069	0.328
MOD_PKA_2	3	9	PF00069	0.647
MOD_PKA_2	402	408	PF00069	0.362
MOD_PKA_2	440	446	PF00069	0.554
MOD_PKA_2	784	790	PF00069	0.656
MOD_PKA_2	865	871	PF00069	0.364
MOD_PKA_2	966	972	PF00069	0.547
MOD_PKA_2	988	994	PF00069	0.264
MOD_Plk_1	165	171	PF00069	0.733
MOD_Plk_1	174	180	PF00069	0.640
MOD_Plk_1	383	389	PF00069	0.407
MOD_Plk_1	441	447	PF00069	0.566
MOD_Plk_1	450	456	PF00069	0.529
MOD_Plk_2-3	187	193	PF00069	0.435
MOD_Plk_4	139	145	PF00069	0.733
MOD_Plk_4	16	22	PF00069	0.600
MOD_Plk_4	198	204	PF00069	0.526
MOD_Plk_4	320	326	PF00069	0.344
MOD_Plk_4	350	356	PF00069	0.445
MOD_Plk_4	402	408	PF00069	0.396
MOD_Plk_4	496	502	PF00069	0.326
MOD_Plk_4	50	56	PF00069	0.552
MOD_Plk_4	765	771	PF00069	0.673
MOD_Plk_4	909	915	PF00069	0.328
MOD_Plk_4	933	939	PF00069	0.433
MOD_ProDKin_1	519	525	PF00069	0.413
MOD_ProDKin_1	595	601	PF00069	0.475
MOD_ProDKin_1	632	638	PF00069	0.328
MOD_ProDKin_1	67	73	PF00069	0.643
MOD_ProDKin_1	89	95	PF00069	0.699
MOD_ProDKin_1	98	104	PF00069	0.635
MOD_SUMO_rev_2	722	731	PF00179	0.460
MOD_SUMO_rev_2	878	885	PF00179	0.417
MOD_SUMO_rev_2	942	949	PF00179	0.548
TRG_DiLeu_BaEn_1	643	648	PF01217	0.328
TRG_DiLeu_BaEn_1	881	886	PF01217	0.398
TRG_DiLeu_BaEn_4	728	734	PF01217	0.568
TRG_DiLeu_BaLyEn_6	287	292	PF01217	0.428
TRG_DiLeu_BaLyEn_6	426	431	PF01217	0.571
TRG_DiLeu_BaLyEn_6	596	601	PF01217	0.300
TRG_DiLeu_BaLyEn_6	83	88	PF01217	0.620
TRG_DiLeu_BaLyEn_6	936	941	PF01217	0.493
TRG_ENDOCYTIC_2	188	191	PF00928	0.543
TRG_ENDOCYTIC_2	25	28	PF00928	0.647
TRG_ENDOCYTIC_2	261	264	PF00928	0.328
TRG_ENDOCYTIC_2	299	302	PF00928	0.413
TRG_ENDOCYTIC_2	645	648	PF00928	0.344
TRG_ENDOCYTIC_2	683	686	PF00928	0.490
TRG_ENDOCYTIC_2	714	717	PF00928	0.358
TRG_ENDOCYTIC_2	758	761	PF00928	0.446
TRG_ENDOCYTIC_2	766	769	PF00928	0.491
TRG_ENDOCYTIC_2	800	803	PF00928	0.580
TRG_ENDOCYTIC_2	938	941	PF00928	0.484
TRG_ER_diArg_1	591	593	PF00400	0.449
TRG_ER_diArg_1	783	786	PF00400	0.676
TRG_ER_diArg_1	863	866	PF00400	0.334
TRG_ER_diArg_1	871	874	PF00400	0.319
TRG_ER_diArg_1	927	929	PF00400	0.344
TRG_NES_CRM1_1	788	798	PF08389	0.620
TRG_NLS_MonoExtC_3	366	371	PF00514	0.437
TRG_Pf-PMV_PEXEL_1	820	824	PF00026	0.449

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5A7	Leptomonas seymouri	68%	93%
A0A0S4IUR7	Bodo saltans	41%	97%
A0A1X0NNS9	Trypanosomatidae	48%	94%
A0A3R7NZA3	Trypanosoma rangeli	48%	94%
A4H7G5	Leishmania braziliensis	90%	100%
A4HVU6	Leishmania infantum	100%	100%
B6EU02	Leishmania tarentolae	94%	93%
C9ZT80	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	45%	95%
E9APJ8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%
Q4DCH3	Trypanosoma cruzi (strain CL Brener)	48%	94%
Q4QFY1	Leishmania major	97%	100%
Q57X81	Trypanosoma brucei brucei (strain 927/4 GUTat10.1)	45%	95%
V5BHQ6	Trypanosoma cruzi	49%	94%