LeishMANIAdb
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39S ribosomal protein L16, mitochondrial

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
39S ribosomal protein L16, mitochondrial
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7WSK9_LEIDO
TriTrypDb:
LdBPK_131100.1 , LdCL_130016300 , LDHU3_13.1360
Length:
185

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. yes yes: 9
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Cellular components
Term Name Level Count
GO:0005737 cytoplasm 2 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

A0A3S7WSK9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WSK9

PDB structure(s): 7aih_P , 7ane_P

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 51 53 PF00675 0.528
CLV_PCSK_KEX2_1 50 52 PF00082 0.511
CLV_PCSK_SKI1_1 117 121 PF00082 0.448
DEG_APCC_DBOX_1 136 144 PF00400 0.543
DEG_Nend_Nbox_1 1 3 PF02207 0.586
DOC_CKS1_1 36 41 PF01111 0.427
DOC_MAPK_gen_1 123 130 PF00069 0.578
DOC_PP4_FxxP_1 162 165 PF00568 0.440
DOC_PP4_FxxP_1 175 178 PF00568 0.352
DOC_WW_Pin1_4 2 7 PF00397 0.657
DOC_WW_Pin1_4 21 26 PF00397 0.582
DOC_WW_Pin1_4 35 40 PF00397 0.368
LIG_14-3-3_CanoR_1 123 129 PF00244 0.504
LIG_14-3-3_CanoR_1 181 185 PF00244 0.507
LIG_DCNL_PONY_1 1 4 PF03556 0.662
LIG_FHA_1 167 173 PF00498 0.578
LIG_FHA_1 74 80 PF00498 0.431
LIG_FHA_1 81 87 PF00498 0.384
LIG_FHA_1 89 95 PF00498 0.429
LIG_FHA_2 39 45 PF00498 0.470
LIG_LIR_Apic_2 159 165 PF02991 0.446
LIG_LIR_Gen_1 97 107 PF02991 0.507
LIG_LIR_Nem_3 76 80 PF02991 0.404
LIG_LIR_Nem_3 97 103 PF02991 0.502
LIG_MYND_1 174 178 PF01753 0.530
LIG_PTB_Apo_2 92 99 PF02174 0.429
LIG_PTB_Phospho_1 92 98 PF10480 0.432
LIG_SH2_STAP1 9 13 PF00017 0.633
LIG_SH2_STAT3 58 61 PF00017 0.594
LIG_SH3_3 140 146 PF00018 0.569
LIG_SH3_3 33 39 PF00018 0.440
MOD_CDK_SPK_2 21 26 PF00069 0.604
MOD_CDK_SPxK_1 2 8 PF00069 0.636
MOD_CDK_SPxxK_3 21 28 PF00069 0.582
MOD_CDK_SPxxK_3 38 45 PF00069 0.345
MOD_CK1_1 11 17 PF00069 0.584
MOD_CK2_1 38 44 PF00069 0.441
MOD_GSK3_1 4 11 PF00069 0.655
MOD_GSK3_1 75 82 PF00069 0.419
MOD_GSK3_1 85 92 PF00069 0.405
MOD_NEK2_1 79 84 PF00069 0.405
MOD_NEK2_2 85 90 PF00069 0.396
MOD_PKA_2 56 62 PF00069 0.522
MOD_PKA_2 89 95 PF00069 0.415
MOD_Plk_4 124 130 PF00069 0.501
MOD_ProDKin_1 2 8 PF00069 0.658
MOD_ProDKin_1 21 27 PF00069 0.575
MOD_ProDKin_1 35 41 PF00069 0.370
TRG_ENDOCYTIC_2 98 101 PF00928 0.373
TRG_ER_diArg_1 111 114 PF00400 0.470
TRG_ER_diArg_1 50 52 PF00400 0.482

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IMF0 Leptomonas seymouri 85% 100%
A0A0S4JV89 Bodo saltans 62% 100%
A0A1X0NMX1 Trypanosomatidae 77% 100%
A0A422NLH3 Trypanosoma rangeli 77% 100%
A4H7A4 Leishmania braziliensis 92% 100%
A4HVP8 Leishmania infantum 99% 100%
E9APE4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 94% 100%
Q4QG34 Leishmania major 98% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS