N(1)-alpha-phosphoribosyltransferase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania donovani

UniProt:

A0A3S7WSK5_LEIDO

TriTrypDb:

LdCL_130012800 , LDHU3_13.0940

Length:

1085

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WSK5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WSK5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	400	404	PF00656	0.538
CLV_C14_Caspase3-7	688	692	PF00656	0.624
CLV_NRD_NRD_1	1050	1052	PF00675	0.677
CLV_NRD_NRD_1	400	402	PF00675	0.535
CLV_NRD_NRD_1	511	513	PF00675	0.679
CLV_NRD_NRD_1	582	584	PF00675	0.680
CLV_NRD_NRD_1	656	658	PF00675	0.628
CLV_NRD_NRD_1	704	706	PF00675	0.611
CLV_NRD_NRD_1	726	728	PF00675	0.725
CLV_NRD_NRD_1	802	804	PF00675	0.618
CLV_NRD_NRD_1	838	840	PF00675	0.625
CLV_NRD_NRD_1	953	955	PF00675	0.675
CLV_NRD_NRD_1	974	976	PF00675	0.630
CLV_PCSK_KEX2_1	1050	1052	PF00082	0.677
CLV_PCSK_KEX2_1	1077	1079	PF00082	0.638
CLV_PCSK_KEX2_1	511	513	PF00082	0.679
CLV_PCSK_KEX2_1	582	584	PF00082	0.680
CLV_PCSK_KEX2_1	633	635	PF00082	0.555
CLV_PCSK_KEX2_1	704	706	PF00082	0.611
CLV_PCSK_KEX2_1	725	727	PF00082	0.763
CLV_PCSK_KEX2_1	802	804	PF00082	0.618
CLV_PCSK_KEX2_1	838	840	PF00082	0.625
CLV_PCSK_KEX2_1	974	976	PF00082	0.630
CLV_PCSK_PC1ET2_1	1077	1079	PF00082	0.638
CLV_PCSK_PC1ET2_1	633	635	PF00082	0.555
CLV_PCSK_PC7_1	629	635	PF00082	0.492
CLV_PCSK_PC7_1	722	728	PF00082	0.635
CLV_PCSK_SKI1_1	600	604	PF00082	0.620
CLV_PCSK_SKI1_1	652	656	PF00082	0.532
CLV_PCSK_SKI1_1	679	683	PF00082	0.679
CLV_PCSK_SKI1_1	872	876	PF00082	0.676
CLV_PCSK_SKI1_1	912	916	PF00082	0.530
DEG_APCC_DBOX_1	628	636	PF00400	0.487
DEG_SCF_FBW7_1	1069	1076	PF00400	0.667
DEG_SPOP_SBC_1	493	497	PF00917	0.548
DEG_SPOP_SBC_1	697	701	PF00917	0.626
DEG_SPOP_SBC_1	848	852	PF00917	0.649
DEG_SPOP_SBC_1	964	968	PF00917	0.600
DOC_CYCLIN_RxL_1	597	606	PF00134	0.614
DOC_MAPK_MEF2A_6	954	963	PF00069	0.601
DOC_MAPK_RevD_3	570	583	PF00069	0.495
DOC_PP1_RVXF_1	925	931	PF00149	0.571
DOC_PP4_FxxP_1	751	754	PF00568	0.609
DOC_USP7_MATH_1	1053	1057	PF00917	0.661
DOC_USP7_MATH_1	1059	1063	PF00917	0.564
DOC_USP7_MATH_1	568	572	PF00917	0.562
DOC_USP7_MATH_1	666	670	PF00917	0.630
DOC_USP7_MATH_1	671	675	PF00917	0.576
DOC_USP7_MATH_1	697	701	PF00917	0.626
DOC_USP7_MATH_1	848	852	PF00917	0.649
DOC_USP7_MATH_1	940	944	PF00917	0.564
DOC_USP7_MATH_1	964	968	PF00917	0.773
DOC_USP7_MATH_1	988	992	PF00917	0.611
DOC_USP7_UBL2_3	398	402	PF12436	0.539
DOC_USP7_UBL2_3	927	931	PF12436	0.418
DOC_WW_Pin1_4	1024	1029	PF00397	0.714
DOC_WW_Pin1_4	1034	1039	PF00397	0.715
DOC_WW_Pin1_4	1044	1049	PF00397	0.621
DOC_WW_Pin1_4	1069	1074	PF00397	0.670
DOC_WW_Pin1_4	387	392	PF00397	0.583
DOC_WW_Pin1_4	406	411	PF00397	0.622
DOC_WW_Pin1_4	454	459	PF00397	0.545
DOC_WW_Pin1_4	489	494	PF00397	0.758
DOC_WW_Pin1_4	500	505	PF00397	0.714
DOC_WW_Pin1_4	542	547	PF00397	0.633
DOC_WW_Pin1_4	570	575	PF00397	0.585
DOC_WW_Pin1_4	606	611	PF00397	0.598
DOC_WW_Pin1_4	657	662	PF00397	0.638
LIG_14-3-3_CanoR_1	1034	1038	PF00244	0.725
LIG_14-3-3_CanoR_1	489	493	PF00244	0.656
LIG_14-3-3_CanoR_1	600	610	PF00244	0.607
LIG_14-3-3_CanoR_1	629	633	PF00244	0.602
LIG_14-3-3_CanoR_1	637	643	PF00244	0.590
LIG_14-3-3_CanoR_1	672	676	PF00244	0.607
LIG_14-3-3_CanoR_1	679	689	PF00244	0.716
LIG_14-3-3_CanoR_1	839	849	PF00244	0.578
LIG_14-3-3_CanoR_1	954	959	PF00244	0.535
LIG_BIR_II_1	1	5	PF00653	0.627
LIG_BIR_III_2	26	30	PF00653	0.570
LIG_BRCT_BRCA1_1	689	693	PF00533	0.770
LIG_BRCT_BRCA1_1	747	751	PF00533	0.617
LIG_BRCT_BRCA1_1	956	960	PF00533	0.500
LIG_EVH1_2	809	813	PF00568	0.676
LIG_FHA_1	1047	1053	PF00498	0.524
LIG_FHA_1	494	500	PF00498	0.681
LIG_FHA_1	548	554	PF00498	0.675
LIG_FHA_1	574	580	PF00498	0.485
LIG_FHA_1	759	765	PF00498	0.643
LIG_FHA_1	8	14	PF00498	0.660
LIG_FHA_1	844	850	PF00498	0.654
LIG_FHA_2	388	394	PF00498	0.599
LIG_FHA_2	651	657	PF00498	0.602
LIG_FHA_2	686	692	PF00498	0.681
LIG_FHA_2	810	816	PF00498	0.660
LIG_FHA_2	890	896	PF00498	0.615
LIG_LIR_Apic_2	108	113	PF02991	0.517
LIG_LIR_Apic_2	129	134	PF02991	0.532
LIG_LIR_Apic_2	150	155	PF02991	0.497
LIG_LIR_Apic_2	171	176	PF02991	0.511
LIG_LIR_Apic_2	192	197	PF02991	0.474
LIG_LIR_Apic_2	213	218	PF02991	0.481
LIG_LIR_Apic_2	234	239	PF02991	0.487
LIG_LIR_Apic_2	255	260	PF02991	0.487
LIG_LIR_Apic_2	276	281	PF02991	0.487
LIG_LIR_Apic_2	297	302	PF02991	0.486
LIG_LIR_Apic_2	318	323	PF02991	0.487
LIG_LIR_Apic_2	360	365	PF02991	0.538
LIG_LIR_Apic_2	368	374	PF02991	0.535
LIG_LIR_Apic_2	45	50	PF02991	0.596
LIG_LIR_Apic_2	554	560	PF02991	0.601
LIG_LIR_Apic_2	66	71	PF02991	0.558
LIG_LIR_Apic_2	674	678	PF02991	0.665
LIG_LIR_Apic_2	748	754	PF02991	0.613
LIG_LIR_Apic_2	87	92	PF02991	0.522
LIG_LIR_Gen_1	339	348	PF02991	0.490
LIG_LIR_Gen_1	957	965	PF02991	0.514
LIG_LIR_LC3C_4	575	580	PF02991	0.480
LIG_LIR_Nem_3	339	344	PF02991	0.484
LIG_LIR_Nem_3	597	601	PF02991	0.682
LIG_LIR_Nem_3	740	744	PF02991	0.615
LIG_LIR_Nem_3	776	781	PF02991	0.674
LIG_LIR_Nem_3	957	963	PF02991	0.512
LIG_PCNA_yPIPBox_3	887	897	PF02747	0.577
LIG_SH2_CRK	110	114	PF00017	0.529
LIG_SH2_CRK	131	135	PF00017	0.546
LIG_SH2_CRK	152	156	PF00017	0.511
LIG_SH2_CRK	173	177	PF00017	0.681
LIG_SH2_CRK	194	198	PF00017	0.488
LIG_SH2_CRK	215	219	PF00017	0.492
LIG_SH2_CRK	236	240	PF00017	0.493
LIG_SH2_CRK	257	261	PF00017	0.500
LIG_SH2_CRK	278	282	PF00017	0.626
LIG_SH2_CRK	299	303	PF00017	0.483
LIG_SH2_CRK	320	324	PF00017	0.470
LIG_SH2_CRK	341	345	PF00017	0.501
LIG_SH2_CRK	362	366	PF00017	0.542
LIG_SH2_CRK	47	51	PF00017	0.599
LIG_SH2_CRK	675	679	PF00017	0.669
LIG_SH2_CRK	68	72	PF00017	0.558
LIG_SH2_CRK	89	93	PF00017	0.536
LIG_SH2_GRB2like	743	746	PF00017	0.597
LIG_SH2_NCK_1	110	114	PF00017	0.529
LIG_SH2_NCK_1	131	135	PF00017	0.546
LIG_SH2_NCK_1	152	156	PF00017	0.483
LIG_SH2_NCK_1	173	177	PF00017	0.541
LIG_SH2_NCK_1	194	198	PF00017	0.488
LIG_SH2_NCK_1	215	219	PF00017	0.492
LIG_SH2_NCK_1	236	240	PF00017	0.493
LIG_SH2_NCK_1	257	261	PF00017	0.500
LIG_SH2_NCK_1	278	282	PF00017	0.626
LIG_SH2_NCK_1	299	303	PF00017	0.483
LIG_SH2_NCK_1	320	324	PF00017	0.470
LIG_SH2_NCK_1	362	366	PF00017	0.542
LIG_SH2_NCK_1	47	51	PF00017	0.599
LIG_SH2_NCK_1	557	561	PF00017	0.621
LIG_SH2_NCK_1	68	72	PF00017	0.558
LIG_SH2_NCK_1	89	93	PF00017	0.536
LIG_SH2_SRC	752	755	PF00017	0.509
LIG_SH2_STAP1	341	345	PF00017	0.487
LIG_SH2_STAP1	547	551	PF00017	0.522
LIG_SH2_STAP1	598	602	PF00017	0.627
LIG_SH2_STAT3	1071	1074	PF00017	0.645
LIG_SH2_STAT5	1071	1074	PF00017	0.701
LIG_SH2_STAT5	601	604	PF00017	0.614
LIG_SH2_STAT5	644	647	PF00017	0.590
LIG_SH2_STAT5	741	744	PF00017	0.578
LIG_SH2_STAT5	752	755	PF00017	0.465
LIG_SH2_STAT5	904	907	PF00017	0.556
LIG_SH3_1	777	783	PF00018	0.620
LIG_SH3_3	10	16	PF00018	0.629
LIG_SH3_3	1022	1028	PF00018	0.666
LIG_SH3_3	380	386	PF00018	0.608
LIG_SH3_3	458	464	PF00018	0.633
LIG_SH3_3	499	505	PF00018	0.818
LIG_SH3_3	515	521	PF00018	0.573
LIG_SH3_3	637	643	PF00018	0.642
LIG_SH3_3	751	757	PF00018	0.577
LIG_SH3_3	777	783	PF00018	0.684
LIG_SH3_3	958	964	PF00018	0.714
LIG_SUMO_SIM_anti_2	575	581	PF11976	0.397
LIG_SUMO_SIM_par_1	609	616	PF11976	0.529
LIG_TRAF2_1	119	122	PF00917	0.520
LIG_TRAF2_1	140	143	PF00917	0.516
LIG_TRAF2_1	161	164	PF00917	0.529
LIG_TRAF2_1	176	179	PF00917	0.520
LIG_TRAF2_1	182	185	PF00917	0.533
LIG_TRAF2_1	203	206	PF00917	0.476
LIG_TRAF2_1	224	227	PF00917	0.503
LIG_TRAF2_1	239	242	PF00917	0.520
LIG_TRAF2_1	266	269	PF00917	0.503
LIG_TRAF2_1	281	284	PF00917	0.503
LIG_TRAF2_1	29	32	PF00917	0.640
LIG_TRAF2_1	302	305	PF00917	0.476
LIG_TRAF2_1	323	326	PF00917	0.477
LIG_TRAF2_1	35	38	PF00917	0.569
LIG_TRAF2_1	391	394	PF00917	0.618
LIG_TRAF2_1	50	53	PF00917	0.529
LIG_TRAF2_1	56	59	PF00917	0.513
LIG_TRAF2_1	734	737	PF00917	0.497
LIG_TRAF2_1	77	80	PF00917	0.528
LIG_TRAF2_1	892	895	PF00917	0.617
LIG_TRAF2_1	98	101	PF00917	0.511
LIG_TYR_ITIM	764	769	PF00017	0.660
LIG_WW_3	808	812	PF00397	0.680
MOD_CDC14_SPxK_1	1047	1050	PF00782	0.530
MOD_CDK_SPxK_1	1044	1050	PF00069	0.540
MOD_CDK_SPxxK_3	1044	1051	PF00069	0.537
MOD_CK1_1	1044	1050	PF00069	0.694
MOD_CK1_1	1079	1085	PF00069	0.692
MOD_CK1_1	466	472	PF00069	0.530
MOD_CK1_1	492	498	PF00069	0.634
MOD_CK1_1	648	654	PF00069	0.547
MOD_CK1_1	680	686	PF00069	0.567
MOD_CK1_1	786	792	PF00069	0.781
MOD_CK1_1	840	846	PF00069	0.679
MOD_CK1_1	850	856	PF00069	0.619
MOD_CK1_1	870	876	PF00069	0.521
MOD_CK1_1	943	949	PF00069	0.596
MOD_CK1_1	967	973	PF00069	0.737
MOD_CK2_1	1003	1009	PF00069	0.635
MOD_CK2_1	387	393	PF00069	0.707
MOD_CK2_1	488	494	PF00069	0.647
MOD_CK2_1	650	656	PF00069	0.599
MOD_CK2_1	731	737	PF00069	0.621
MOD_CK2_1	809	815	PF00069	0.666
MOD_CK2_1	850	856	PF00069	0.626
MOD_CK2_1	889	895	PF00069	0.630
MOD_CK2_1	984	990	PF00069	0.605
MOD_Cter_Amidation	972	975	PF01082	0.671
MOD_DYRK1A_RPxSP_1	1034	1038	PF00069	0.649
MOD_DYRK1A_RPxSP_1	489	493	PF00069	0.656
MOD_GlcNHglycan	1005	1008	PF01048	0.771
MOD_GlcNHglycan	1043	1046	PF01048	0.742
MOD_GlcNHglycan	1081	1084	PF01048	0.704
MOD_GlcNHglycan	371	374	PF01048	0.552
MOD_GlcNHglycan	451	455	PF01048	0.741
MOD_GlcNHglycan	467	471	PF01048	0.635
MOD_GlcNHglycan	568	571	PF01048	0.521
MOD_GlcNHglycan	669	672	PF01048	0.654
MOD_GlcNHglycan	682	685	PF01048	0.574
MOD_GlcNHglycan	788	791	PF01048	0.663
MOD_GlcNHglycan	852	855	PF01048	0.626
MOD_GlcNHglycan	942	945	PF01048	0.715
MOD_GlcNHglycan	956	959	PF01048	0.569
MOD_GlcNHglycan	971	974	PF01048	0.722
MOD_GlcNHglycan	986	989	PF01048	0.609
MOD_GSK3_1	1020	1027	PF00069	0.759
MOD_GSK3_1	1069	1076	PF00069	0.712
MOD_GSK3_1	439	446	PF00069	0.577
MOD_GSK3_1	450	457	PF00069	0.608
MOD_GSK3_1	488	495	PF00069	0.634
MOD_GSK3_1	516	523	PF00069	0.720
MOD_GSK3_1	536	543	PF00069	0.669
MOD_GSK3_1	566	573	PF00069	0.561
MOD_GSK3_1	602	609	PF00069	0.718
MOD_GSK3_1	613	620	PF00069	0.543
MOD_GSK3_1	667	674	PF00069	0.636
MOD_GSK3_1	685	692	PF00069	0.716
MOD_GSK3_1	693	700	PF00069	0.715
MOD_GSK3_1	713	720	PF00069	0.402
MOD_GSK3_1	809	816	PF00069	0.663
MOD_GSK3_1	843	850	PF00069	0.688
MOD_GSK3_1	861	868	PF00069	0.587
MOD_GSK3_1	885	892	PF00069	0.719
MOD_GSK3_1	963	970	PF00069	0.807
MOD_GSK3_1	984	991	PF00069	0.567
MOD_N-GLC_1	1069	1074	PF02516	0.726
MOD_N-GLC_1	424	429	PF02516	0.672
MOD_N-GLC_1	443	448	PF02516	0.553
MOD_N-GLC_1	638	643	PF02516	0.641
MOD_NEK2_1	540	545	PF00069	0.610
MOD_NEK2_1	613	618	PF00069	0.637
MOD_NEK2_1	682	687	PF00069	0.646
MOD_NEK2_1	689	694	PF00069	0.649
MOD_NEK2_1	795	800	PF00069	0.584
MOD_NEK2_1	813	818	PF00069	0.641
MOD_NEK2_1	823	828	PF00069	0.621
MOD_NEK2_1	882	887	PF00069	0.657
MOD_NEK2_1	969	974	PF00069	0.636
MOD_NEK2_2	628	633	PF00069	0.553
MOD_NEK2_2	796	801	PF00069	0.646
MOD_NEK2_2	867	872	PF00069	0.688
MOD_PIKK_1	30	36	PF00454	0.539
MOD_PIKK_1	516	522	PF00454	0.606
MOD_PIKK_1	823	829	PF00454	0.701
MOD_PIKK_1	861	867	PF00454	0.687
MOD_PIKK_1	882	888	PF00454	0.657
MOD_PKA_1	633	639	PF00069	0.553
MOD_PKA_1	954	960	PF00069	0.522
MOD_PKA_2	1033	1039	PF00069	0.705
MOD_PKA_2	488	494	PF00069	0.660
MOD_PKA_2	628	634	PF00069	0.624
MOD_PKA_2	671	677	PF00069	0.622
MOD_PKA_2	685	691	PF00069	0.573
MOD_PKA_2	7	13	PF00069	0.657
MOD_PKA_2	786	792	PF00069	0.649
MOD_PKA_2	837	843	PF00069	0.754
MOD_PKB_1	887	895	PF00069	0.573
MOD_Plk_1	439	445	PF00069	0.547
MOD_Plk_1	466	472	PF00069	0.613
MOD_Plk_1	585	591	PF00069	0.670
MOD_Plk_1	613	619	PF00069	0.617
MOD_Plk_1	645	651	PF00069	0.672
MOD_Plk_4	573	579	PF00069	0.463
MOD_Plk_4	758	764	PF00069	0.721
MOD_Plk_4	988	994	PF00069	0.561
MOD_ProDKin_1	1024	1030	PF00069	0.718
MOD_ProDKin_1	1034	1040	PF00069	0.709
MOD_ProDKin_1	1044	1050	PF00069	0.619
MOD_ProDKin_1	1069	1075	PF00069	0.666
MOD_ProDKin_1	387	393	PF00069	0.585
MOD_ProDKin_1	406	412	PF00069	0.622
MOD_ProDKin_1	454	460	PF00069	0.546
MOD_ProDKin_1	489	495	PF00069	0.760
MOD_ProDKin_1	500	506	PF00069	0.711
MOD_ProDKin_1	542	548	PF00069	0.634
MOD_ProDKin_1	570	576	PF00069	0.578
MOD_ProDKin_1	606	612	PF00069	0.590
MOD_ProDKin_1	657	663	PF00069	0.638
MOD_SUMO_for_1	421	424	PF00179	0.633
MOD_SUMO_rev_2	394	404	PF00179	0.635
MOD_SUMO_rev_2	414	423	PF00179	0.641
MOD_SUMO_rev_2	651	660	PF00179	0.617
MOD_SUMO_rev_2	920	928	PF00179	0.548
TRG_ENDOCYTIC_2	341	344	PF00928	0.489
TRG_ENDOCYTIC_2	766	769	PF00928	0.660
TRG_ER_diArg_1	1050	1052	PF00400	0.699
TRG_ER_diArg_1	510	512	PF00400	0.685
TRG_ER_diArg_1	581	583	PF00400	0.668
TRG_ER_diArg_1	703	705	PF00400	0.616
TRG_ER_diArg_1	725	727	PF00400	0.648
TRG_ER_diArg_1	837	839	PF00400	0.685
TRG_ER_diArg_1	974	976	PF00400	0.657
TRG_Pf-PMV_PEXEL_1	891	895	PF00026	0.668
TRG_Pf-PMV_PEXEL_1	921	925	PF00026	0.546

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4H773	Leishmania braziliensis	60%	100%
A4HVL3	Leishmania infantum	94%	96%
E9APA9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	79%	100%
Q4QG69	Leishmania major	82%	100%