Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7WSC0_LEIDO

TriTrypDb:

LdBPK_130120.1 , LdCL_130006200 , LDHU3_13.0150

Length:

119


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0051286	cell tip	3	1
GO:0060187	cell pole	2	1
GO:0110165	cellular anatomical entity	1	1

A0A3S7WSC0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WSC0


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	54	58	PF00656	0.606
CLV_NRD_NRD_1	22	24	PF00675	0.518
CLV_NRD_NRD_1	32	34	PF00675	0.558
CLV_NRD_NRD_1	72	74	PF00675	0.536
CLV_PCSK_KEX2_1	32	34	PF00082	0.607
CLV_PCSK_KEX2_1	94	96	PF00082	0.431
CLV_PCSK_PC1ET2_1	94	96	PF00082	0.431
DEG_Nend_UBRbox_1	1	4	PF02207	0.495
DOC_MAPK_gen_1	94	100	PF00069	0.592
DOC_WW_Pin1_4	98	103	PF00397	0.541
LIG_14-3-3_CterR_2	115	119	PF00244	0.637
LIG_APCC_ABBA_1	63	68	PF00400	0.436
LIG_APCC_ABBAyCdc20_2	75	81	PF00400	0.532
LIG_BRCT_BRCA1_1	87	91	PF00533	0.527
LIG_LIR_Nem_3	3	7	PF02991	0.537
LIG_MLH1_MIPbox_1	87	91	PF16413	0.527
LIG_PCNA_yPIPBox_3	55	66	PF02747	0.454
LIG_Rb_pABgroove_1	60	68	PF01858	0.486
LIG_REV1ctd_RIR_1	88	99	PF16727	0.537
LIG_SH2_SRC	79	82	PF00017	0.417
LIG_SH2_STAP1	79	83	PF00017	0.445
LIG_SH2_STAT5	103	106	PF00017	0.594
LIG_SH2_STAT5	89	92	PF00017	0.536
LIG_SUMO_SIM_par_1	61	68	PF11976	0.502
LIG_TRAF2_1	82	85	PF00917	0.456
MOD_CDK_SPxxK_3	98	105	PF00069	0.588
MOD_CK1_1	108	114	PF00069	0.680
MOD_GlcNHglycan	107	110	PF01048	0.631
MOD_PIKK_1	108	114	PF00454	0.501
MOD_PIKK_1	32	38	PF00454	0.639
MOD_PKA_1	32	38	PF00069	0.636
MOD_PKA_2	32	38	PF00069	0.603
MOD_ProDKin_1	98	104	PF00069	0.547
MOD_SUMO_for_1	14	17	PF00179	0.533
MOD_SUMO_rev_2	86	96	PF00179	0.535
TRG_ENDOCYTIC_2	66	69	PF00928	0.517
TRG_ENDOCYTIC_2	97	100	PF00928	0.441
TRG_Pf-PMV_PEXEL_1	105	110	PF00026	0.522
TRG_Pf-PMV_PEXEL_1	23	27	PF00026	0.476


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IKU6	Leptomonas seymouri	70%	81%
A0A1X0NNB7	Trypanosomatidae	43%	100%
A0A422NBN3	Trypanosoma rangeli	42%	100%
A4H719	Leishmania braziliensis	80%	100%
A4HVE8	Leishmania infantum	100%	100%
D0A6W2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
E9AP46	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
Q4QGE2	Leishmania major	96%	100%