LeishMANIAdb
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Non-specific serine/threonine protein kinase

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Non-specific serine/threonine protein kinase
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7WS93_LEIDO
TriTrypDb:
LdBPK_120070r.1 * , LdCL_120020000 , LDHU3_12.1580
Length:
1009

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WS93
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WS93

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 385 389 PF00656 0.634
CLV_C14_Caspase3-7 45 49 PF00656 0.630
CLV_C14_Caspase3-7 582 586 PF00656 0.692
CLV_C14_Caspase3-7 678 682 PF00656 0.574
CLV_C14_Caspase3-7 714 718 PF00656 0.618
CLV_C14_Caspase3-7 862 866 PF00656 0.663
CLV_NRD_NRD_1 165 167 PF00675 0.773
CLV_NRD_NRD_1 189 191 PF00675 0.734
CLV_NRD_NRD_1 197 199 PF00675 0.722
CLV_NRD_NRD_1 215 217 PF00675 0.531
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Homologs

ProteinTaxonomySequence identityCoverage
A4H701 Leishmania braziliensis 59% 97%
E9AGH4 Leishmania infantum 99% 100%
E9AP21 Leishmania mexicana (strain MHOM/GT/2001/U1103) 77% 98%
Q4QGG8 Leishmania major 83% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS