Glyco_transf_20 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7WS03_LEIDO

TriTrypDb:

LdBPK_120265.1 , LdCL_120008200 , LDHU3_12.0430

Length:

644

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	7
GO:0110165	cellular anatomical entity	1	7

Expansion

Sequence features

A0A3S7WS03

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WS03

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	611	615	PF00656	0.582
CLV_NRD_NRD_1	219	221	PF00675	0.451
CLV_NRD_NRD_1	306	308	PF00675	0.499
CLV_NRD_NRD_1	403	405	PF00675	0.398
CLV_NRD_NRD_1	48	50	PF00675	0.400
CLV_PCSK_KEX2_1	182	184	PF00082	0.429
CLV_PCSK_KEX2_1	219	221	PF00082	0.451
CLV_PCSK_KEX2_1	241	243	PF00082	0.403
CLV_PCSK_KEX2_1	273	275	PF00082	0.402
CLV_PCSK_KEX2_1	297	299	PF00082	0.476
CLV_PCSK_KEX2_1	305	307	PF00082	0.499
CLV_PCSK_KEX2_1	48	50	PF00082	0.400
CLV_PCSK_PC1ET2_1	182	184	PF00082	0.429
CLV_PCSK_PC1ET2_1	241	243	PF00082	0.403
CLV_PCSK_PC1ET2_1	273	275	PF00082	0.402
CLV_PCSK_PC1ET2_1	297	299	PF00082	0.476
CLV_PCSK_SKI1_1	25	29	PF00082	0.389
CLV_PCSK_SKI1_1	270	274	PF00082	0.412
CLV_Separin_Metazoa	199	203	PF03568	0.607
DEG_APCC_DBOX_1	455	463	PF00400	0.603
DEG_MDM2_SWIB_1	259	266	PF02201	0.574
DEG_Nend_UBRbox_4	1	3	PF02207	0.393
DEG_SPOP_SBC_1	106	110	PF00917	0.646
DOC_CDC14_PxL_1	240	248	PF14671	0.624
DOC_CKS1_1	158	163	PF01111	0.692
DOC_CKS1_1	26	31	PF01111	0.611
DOC_CYCLIN_yCln2_LP_2	26	32	PF00134	0.610
DOC_CYCLIN_yCln2_LP_2	335	341	PF00134	0.595
DOC_MAPK_DCC_7	344	353	PF00069	0.612
DOC_MAPK_gen_1	171	181	PF00069	0.649
DOC_MAPK_HePTP_8	341	353	PF00069	0.615
DOC_MAPK_MEF2A_6	344	353	PF00069	0.622
DOC_PP2B_LxvP_1	104	107	PF13499	0.725
DOC_PP2B_LxvP_1	121	124	PF13499	0.614
DOC_PP2B_LxvP_1	13	16	PF13499	0.261
DOC_PP2B_LxvP_1	141	144	PF13499	0.561
DOC_PP2B_LxvP_1	210	213	PF13499	0.637
DOC_PP2B_LxvP_1	335	338	PF13499	0.594
DOC_PP2B_LxvP_1	346	349	PF13499	0.618
DOC_USP7_MATH_1	107	111	PF00917	0.588
DOC_USP7_MATH_1	211	215	PF00917	0.686
DOC_USP7_MATH_1	349	353	PF00917	0.626
DOC_USP7_MATH_1	370	374	PF00917	0.669
DOC_USP7_MATH_1	454	458	PF00917	0.634
DOC_USP7_MATH_1	484	488	PF00917	0.624
DOC_USP7_MATH_1	5	9	PF00917	0.404
DOC_USP7_MATH_1	500	504	PF00917	0.598
DOC_USP7_MATH_1	507	511	PF00917	0.578
DOC_USP7_MATH_1	606	610	PF00917	0.670
DOC_USP7_MATH_1	87	91	PF00917	0.648
DOC_USP7_UBL2_3	414	418	PF12436	0.582
DOC_USP7_UBL2_3	595	599	PF12436	0.575
DOC_WW_Pin1_4	157	162	PF00397	0.693
DOC_WW_Pin1_4	25	30	PF00397	0.589
DOC_WW_Pin1_4	312	317	PF00397	0.704
DOC_WW_Pin1_4	344	349	PF00397	0.622
DOC_WW_Pin1_4	379	384	PF00397	0.605
DOC_WW_Pin1_4	391	396	PF00397	0.580
DOC_WW_Pin1_4	61	66	PF00397	0.609
LIG_14-3-3_CanoR_1	377	383	PF00244	0.653
LIG_14-3-3_CanoR_1	456	464	PF00244	0.603
LIG_14-3-3_CanoR_1	542	552	PF00244	0.321
LIG_Actin_WH2_2	227	243	PF00022	0.596
LIG_BIR_III_2	322	326	PF00653	0.611
LIG_BRCT_BRCA1_1	381	385	PF00533	0.613
LIG_BRCT_BRCA1_1	488	492	PF00533	0.588
LIG_BRCT_BRCA1_1	518	522	PF00533	0.447
LIG_CtBP_PxDLS_1	124	128	PF00389	0.618
LIG_EH1_1	551	559	PF00400	0.273
LIG_eIF4E_1	552	558	PF01652	0.273
LIG_FHA_1	227	233	PF00498	0.596
LIG_FHA_1	249	255	PF00498	0.658
LIG_FHA_1	26	32	PF00498	0.587
LIG_FHA_1	286	292	PF00498	0.628
LIG_FHA_1	459	465	PF00498	0.596
LIG_FHA_1	557	563	PF00498	0.304
LIG_FHA_2	38	44	PF00498	0.581
LIG_FHA_2	392	398	PF00498	0.657
LIG_FHA_2	458	464	PF00498	0.607
LIG_FHA_2	84	90	PF00498	0.609
LIG_LIR_Gen_1	10	20	PF02991	0.261
LIG_LIR_Gen_1	258	267	PF02991	0.589
LIG_LIR_Gen_1	332	341	PF02991	0.617
LIG_LIR_Gen_1	382	393	PF02991	0.624
LIG_LIR_Gen_1	510	518	PF02991	0.578
LIG_LIR_Gen_1	545	555	PF02991	0.247
LIG_LIR_Nem_3	10	15	PF02991	0.261
LIG_LIR_Nem_3	258	262	PF02991	0.584
LIG_LIR_Nem_3	332	336	PF02991	0.638
LIG_LIR_Nem_3	382	388	PF02991	0.648
LIG_LIR_Nem_3	417	423	PF02991	0.607
LIG_LIR_Nem_3	466	470	PF02991	0.620
LIG_LIR_Nem_3	510	514	PF02991	0.585
LIG_LIR_Nem_3	545	551	PF02991	0.326
LIG_NRBOX	30	36	PF00104	0.619
LIG_Pex14_1	263	267	PF04695	0.581
LIG_Pex14_1	548	552	PF04695	0.247
LIG_Pex14_2	259	263	PF04695	0.575
LIG_SH2_CRK	333	337	PF00017	0.606
LIG_SH2_CRK	421	425	PF00017	0.586
LIG_SH2_CRK	552	556	PF00017	0.273
LIG_SH2_NCK_1	552	556	PF00017	0.273
LIG_SH2_PTP2	23	26	PF00017	0.515
LIG_SH2_STAP1	333	337	PF00017	0.606
LIG_SH2_STAP1	511	515	PF00017	0.585
LIG_SH2_STAT5	137	140	PF00017	0.610
LIG_SH2_STAT5	23	26	PF00017	0.484
LIG_SH2_STAT5	267	270	PF00017	0.583
LIG_SH2_STAT5	480	483	PF00017	0.661
LIG_SH2_STAT5	537	540	PF00017	0.374
LIG_SH2_STAT5	75	78	PF00017	0.607
LIG_SH3_3	113	119	PF00018	0.667
LIG_SH3_3	158	164	PF00018	0.667
LIG_SH3_3	210	216	PF00018	0.708
LIG_SH3_3	342	348	PF00018	0.621
LIG_SH3_3	466	472	PF00018	0.613
LIG_SUMO_SIM_anti_2	251	256	PF11976	0.582
LIG_SUMO_SIM_par_1	460	466	PF11976	0.601
LIG_TRAF2_1	167	170	PF00917	0.698
LIG_TRAF2_1	362	365	PF00917	0.640
LIG_TYR_ITSM	548	555	PF00017	0.247
MOD_CK1_1	109	115	PF00069	0.645
MOD_CK1_1	157	163	PF00069	0.674
MOD_CK1_1	261	267	PF00069	0.600
MOD_CK1_1	372	378	PF00069	0.683
MOD_CK1_1	441	447	PF00069	0.653
MOD_CK1_1	457	463	PF00069	0.557
MOD_CK1_1	501	507	PF00069	0.673
MOD_CK1_1	7	13	PF00069	0.249
MOD_CK2_1	37	43	PF00069	0.628
MOD_CK2_1	63	69	PF00069	0.610
MOD_DYRK1A_RPxSP_1	344	348	PF00069	0.628
MOD_GlcNHglycan	372	375	PF01048	0.462
MOD_GlcNHglycan	424	427	PF01048	0.451
MOD_GlcNHglycan	440	443	PF01048	0.377
MOD_GlcNHglycan	444	447	PF01048	0.409
MOD_GlcNHglycan	488	491	PF01048	0.452
MOD_GlcNHglycan	500	503	PF01048	0.455
MOD_GlcNHglycan	610	613	PF01048	0.467
MOD_GlcNHglycan	621	624	PF01048	0.396
MOD_GSK3_1	105	112	PF00069	0.760
MOD_GSK3_1	349	356	PF00069	0.596
MOD_GSK3_1	375	382	PF00069	0.619
MOD_GSK3_1	438	445	PF00069	0.714
MOD_GSK3_1	454	461	PF00069	0.548
MOD_GSK3_1	494	501	PF00069	0.690
MOD_GSK3_1	503	510	PF00069	0.581
MOD_GSK3_1	543	550	PF00069	0.321
MOD_GSK3_1	59	66	PF00069	0.627
MOD_GSK3_1	83	90	PF00069	0.609
MOD_N-GLC_1	484	489	PF02516	0.406
MOD_NEK2_1	283	288	PF00069	0.641
MOD_NEK2_1	353	358	PF00069	0.596
MOD_NEK2_1	455	460	PF00069	0.583
MOD_NEK2_1	527	532	PF00069	0.273
MOD_NEK2_1	59	64	PF00069	0.617
MOD_NEK2_1	600	605	PF00069	0.573
MOD_NEK2_1	83	88	PF00069	0.599
MOD_PIKK_1	154	160	PF00454	0.684
MOD_PIKK_1	211	217	PF00454	0.687
MOD_PIKK_1	59	65	PF00454	0.617
MOD_PIKK_1	75	81	PF00454	0.589
MOD_PK_1	516	522	PF00069	0.447
MOD_PKA_2	455	461	PF00069	0.601
MOD_PKB_1	305	313	PF00069	0.636
MOD_PKB_1	474	482	PF00069	0.623
MOD_Plk_1	307	313	PF00069	0.639
MOD_Plk_1	349	355	PF00069	0.610
MOD_Plk_1	484	490	PF00069	0.631
MOD_Plk_1	516	522	PF00069	0.447
MOD_Plk_1	616	622	PF00069	0.574
MOD_Plk_4	117	123	PF00069	0.646
MOD_Plk_4	174	180	PF00069	0.635
MOD_Plk_4	258	264	PF00069	0.587
MOD_Plk_4	476	482	PF00069	0.627
MOD_Plk_4	547	553	PF00069	0.247
MOD_Plk_4	556	562	PF00069	0.273
MOD_Plk_4	7	13	PF00069	0.239
MOD_ProDKin_1	157	163	PF00069	0.690
MOD_ProDKin_1	25	31	PF00069	0.589
MOD_ProDKin_1	312	318	PF00069	0.700
MOD_ProDKin_1	344	350	PF00069	0.624
MOD_ProDKin_1	379	385	PF00069	0.604
MOD_ProDKin_1	391	397	PF00069	0.581
MOD_ProDKin_1	61	67	PF00069	0.607
MOD_SUMO_for_1	181	184	PF00179	0.663
MOD_SUMO_for_1	632	635	PF00179	0.625
MOD_SUMO_rev_2	84	93	PF00179	0.609
TRG_DiLeu_BaEn_1	596	601	PF01217	0.540
TRG_DiLeu_BaLyEn_6	22	27	PF01217	0.510
TRG_DiLeu_BaLyEn_6	278	283	PF01217	0.640
TRG_DiLeu_BaLyEn_6	30	35	PF01217	0.583
TRG_ENDOCYTIC_2	23	26	PF00928	0.515
TRG_ENDOCYTIC_2	333	336	PF00928	0.611
TRG_ENDOCYTIC_2	420	423	PF00928	0.588
TRG_ENDOCYTIC_2	467	470	PF00928	0.617
TRG_ENDOCYTIC_2	511	514	PF00928	0.587
TRG_ENDOCYTIC_2	552	555	PF00928	0.273
TRG_ER_diArg_1	201	204	PF00400	0.645
TRG_ER_diArg_1	304	307	PF00400	0.663
TRG_ER_diArg_1	309	312	PF00400	0.649
TRG_ER_diArg_1	47	49	PF00400	0.568
TRG_ER_diArg_1	583	586	PF00400	0.581
TRG_ER_diLys_1	641	644	PF00400	0.679
TRG_NES_CRM1_1	453	466	PF08389	0.589
TRG_Pf-PMV_PEXEL_1	298	303	PF00026	0.461
TRG_Pf-PMV_PEXEL_1	542	547	PF00026	0.531

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HZL0	Leptomonas seymouri	48%	100%
A4H6U7	Leishmania braziliensis	71%	100%
E9AGB8	Leishmania infantum	98%	100%
E9ANV8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%
Q4QGR2	Leishmania major	90%	100%