LeishMANIAdb
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Transcriptional regulator

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Transcriptional regulator
Gene product:
hypothetical protein
Species:
Leishmania donovani
UniProt:
A0A3S7WRZ5_LEIDO
TriTrypDb:
LdCL_120012700 , LDHU3_12.1370
Length:
155

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 4
NetGPI no yes: 0, no: 4
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WRZ5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WRZ5

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 148 150 PF00675 0.578
CLV_PCSK_KEX2_1 148 150 PF00082 0.578
CLV_PCSK_PC7_1 144 150 PF00082 0.581
CLV_PCSK_SKI1_1 15 19 PF00082 0.370
DEG_APCC_DBOX_1 14 22 PF00400 0.372
DOC_CKS1_1 33 38 PF01111 0.600
DOC_CYCLIN_yCln2_LP_2 38 44 PF00134 0.527
DOC_MAPK_gen_1 12 20 PF00069 0.384
DOC_USP7_MATH_1 42 46 PF00917 0.506
DOC_USP7_MATH_1 71 75 PF00917 0.416
DOC_WW_Pin1_4 32 37 PF00397 0.601
DOC_WW_Pin1_4 43 48 PF00397 0.468
DOC_WW_Pin1_4 82 87 PF00397 0.403
LIG_14-3-3_CanoR_1 106 112 PF00244 0.490
LIG_CtBP_PxDLS_1 86 90 PF00389 0.412
LIG_eIF4E_1 43 49 PF01652 0.469
LIG_EVH1_2 57 61 PF00568 0.479
LIG_FHA_1 33 39 PF00498 0.602
LIG_FHA_2 83 89 PF00498 0.476
LIG_LIR_Gen_1 88 98 PF02991 0.430
LIG_LIR_Nem_3 88 94 PF02991 0.426
LIG_NRBOX 93 99 PF00104 0.430
LIG_OCRL_FandH_1 90 102 PF00620 0.430
LIG_Pex14_2 61 65 PF04695 0.461
LIG_SH3_3 19 25 PF00018 0.403
LIG_SH3_3 27 33 PF00018 0.494
LIG_SH3_3 3 9 PF00018 0.430
LIG_SUMO_SIM_par_1 85 90 PF11976 0.410
MOD_Cter_Amidation 146 149 PF01082 0.581
MOD_DYRK1A_RPxSP_1 32 36 PF00069 0.527
MOD_GlcNHglycan 125 128 PF01048 0.551
MOD_GlcNHglycan 58 61 PF01048 0.560
MOD_GlcNHglycan 91 94 PF01048 0.423
MOD_GSK3_1 123 130 PF00069 0.546
MOD_NEK2_1 123 128 PF00069 0.544
MOD_NEK2_1 61 66 PF00069 0.460
MOD_NEK2_1 87 92 PF00069 0.419
MOD_PKA_2 127 133 PF00069 0.551
MOD_PKB_1 32 40 PF00069 0.526
MOD_Plk_1 87 93 PF00069 0.420
MOD_ProDKin_1 32 38 PF00069 0.602
MOD_ProDKin_1 43 49 PF00069 0.453
MOD_ProDKin_1 82 88 PF00069 0.406
TRG_DiLeu_BaLyEn_6 44 49 PF01217 0.422
TRG_ER_diArg_1 151 154 PF00400 0.601

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8I9B7 Leishmania donovani 98% 100%
A0A3S5H6L4 Leishmania donovani 99% 100%
A0A3S5H6M1 Leishmania donovani 99% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS