LeishMANIAdb
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Transcriptional regulator

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Transcriptional regulator
Gene product:
Iron-containing alcohol dehydrogenase, putative
Species:
Leishmania donovani
UniProt:
A0A3S7WRX0_LEIDO
TriTrypDb:
LdBPK_120380.1 , LdCL_120009400
Length:
69

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 2
NetGPI no yes: 0, no: 2
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WRX0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WRX0

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 38 42 PF00656 0.459
CLV_NRD_NRD_1 20 22 PF00675 0.476
CLV_NRD_NRD_1 64 66 PF00675 0.792
CLV_PCSK_KEX2_1 20 22 PF00082 0.451
CLV_PCSK_KEX2_1 64 66 PF00082 0.661
CLV_PCSK_PC7_1 60 66 PF00082 0.653
CLV_PCSK_SKI1_1 20 24 PF00082 0.446
LIG_Integrin_isoDGR_2 18 20 PF01839 0.444
LIG_PCNA_yPIPBox_3 10 21 PF02747 0.471
LIG_SH3_3 63 69 PF00018 0.680
MOD_CK1_1 35 41 PF00069 0.551
MOD_Cter_Amidation 18 21 PF01082 0.479
MOD_GlcNHglycan 25 28 PF01048 0.444
MOD_GlcNHglycan 34 37 PF01048 0.658
MOD_GlcNHglycan 41 44 PF01048 0.656
MOD_GSK3_1 23 30 PF00069 0.400
MOD_GSK3_1 32 39 PF00069 0.465
MOD_GSK3_1 48 55 PF00069 0.548
MOD_GSK3_1 8 15 PF00069 0.495
MOD_N-GLC_1 23 28 PF02516 0.391
MOD_N-GLC_1 9 14 PF02516 0.501
MOD_NEK2_1 23 28 PF00069 0.442
MOD_PKA_2 39 45 PF00069 0.463
MOD_Plk_1 9 15 PF00069 0.493
MOD_Plk_4 12 18 PF00069 0.514
MOD_Plk_4 27 33 PF00069 0.419
TRG_ER_diArg_1 20 22 PF00400 0.451
TRG_ER_diArg_1 63 65 PF00400 0.565
TRG_Pf-PMV_PEXEL_1 21 25 PF00026 0.448

Homologs

Protein Taxonomy Sequence identity Coverage
E9AGD0 Leishmania infantum 100% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS