LeishMANIAdb
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Organic solute transporter Ostalpha, putative

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Organic solute transporter Ostalpha, putative
Gene product:
Organic solute transporter Ostalpha, putative
Species:
Leishmania donovani
UniProt:
A0A3S7WRT4_LEIDO
TriTrypDb:
LdBPK_111190.1 * , LdCL_110017800 , LDHU3_11.1440
Length:
692

Annotations

LeishMANIAdb annotations

Member of the poorly studied TMEM184 family ubiquitious in Eukaryota.

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 11
GO:0110165 cellular anatomical entity 1 11
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Expansion

Sequence features

A0A3S7WRT4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WRT4

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 562 566 PF00656 0.762
CLV_C14_Caspase3-7 601 605 PF00656 0.644
CLV_NRD_NRD_1 138 140 PF00675 0.344
CLV_NRD_NRD_1 306 308 PF00675 0.372
CLV_NRD_NRD_1 351 353 PF00675 0.444
CLV_NRD_NRD_1 463 465 PF00675 0.442
CLV_NRD_NRD_1 510 512 PF00675 0.434
CLV_NRD_NRD_1 530 532 PF00675 0.561
CLV_PCSK_FUR_1 165 169 PF00082 0.283
CLV_PCSK_KEX2_1 138 140 PF00082 0.285
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P2Y7 Leptomonas seymouri 66% 98%
A0A0S4KNU2 Bodo saltans 48% 100%
A0A1X0NUV4 Trypanosomatidae 60% 100%
A0A3R7KK37 Trypanosoma rangeli 62% 100%
A4H6P0 Leishmania braziliensis 82% 100%
A4HV27 Leishmania infantum 100% 100%
E9ANQ9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 92% 100%
Q4QGW2 Leishmania major 95% 100%
V5BRV8 Trypanosoma cruzi 63% 100%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS