ATP-dependent DNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

PIF1 helicase-like protein, putative

Species:

Leishmania donovani

UniProt:

A0A3S7WRJ2_LEIDO

TriTrypDb:

LdBPK_110320.1 , LdCL_110008100 , LDHU3_11.0410

Length:

1222

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	8
GO:0110165	cellular anatomical entity	1	8
GO:0005657	replication fork	2	1

Expansion

Sequence features

A0A3S7WRJ2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WRJ2

Function

Biological processes
Term	Name	Level	Count
GO:0000723	telomere maintenance	5	8
GO:0006139	nucleobase-containing compound metabolic process	3	8
GO:0006259	DNA metabolic process	4	8
GO:0006281	DNA repair	5	8
GO:0006310	DNA recombination	5	8
GO:0006725	cellular aromatic compound metabolic process	3	8
GO:0006807	nitrogen compound metabolic process	2	8
GO:0006950	response to stress	2	8
GO:0006974	DNA damage response	4	8
GO:0006996	organelle organization	4	8
GO:0008152	metabolic process	1	8
GO:0009987	cellular process	1	8
GO:0016043	cellular component organization	3	8
GO:0032200	telomere organization	6	8
GO:0033554	cellular response to stress	3	8
GO:0034641	cellular nitrogen compound metabolic process	3	8
GO:0043170	macromolecule metabolic process	3	8
GO:0044237	cellular metabolic process	2	8
GO:0044238	primary metabolic process	2	8
GO:0044260	obsolete cellular macromolecule metabolic process	3	8
GO:0046483	heterocycle metabolic process	3	8
GO:0050896	response to stimulus	1	8
GO:0051276	chromosome organization	5	8
GO:0051716	cellular response to stimulus	2	8
GO:0071704	organic substance metabolic process	2	8
GO:0071840	cellular component organization or biogenesis	2	8
GO:0090304	nucleic acid metabolic process	4	8
GO:1901360	organic cyclic compound metabolic process	3	8
GO:0006260	DNA replication	5	1
GO:0032392	DNA geometric change	7	1
GO:0032508	DNA duplex unwinding	8	1
GO:0071103	DNA conformation change	6	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	8
GO:0003678	DNA helicase activity	3	8
GO:0003824	catalytic activity	1	8
GO:0004386	helicase activity	2	8
GO:0005488	binding	1	8
GO:0005524	ATP binding	5	8
GO:0008094	ATP-dependent activity, acting on DNA	2	8
GO:0016462	pyrophosphatase activity	5	8
GO:0016787	hydrolase activity	2	8
GO:0016817	hydrolase activity, acting on acid anhydrides	3	8
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	8
GO:0016887	ATP hydrolysis activity	7	8
GO:0017076	purine nucleotide binding	4	8
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	8
GO:0030554	adenyl nucleotide binding	5	8
GO:0032553	ribonucleotide binding	3	8
GO:0032555	purine ribonucleotide binding	4	8
GO:0032559	adenyl ribonucleotide binding	5	8
GO:0035639	purine ribonucleoside triphosphate binding	4	8
GO:0036094	small molecule binding	2	8
GO:0043167	ion binding	2	8
GO:0043168	anion binding	3	8
GO:0097159	organic cyclic compound binding	2	8
GO:0097367	carbohydrate derivative binding	2	8
GO:0140097	catalytic activity, acting on DNA	3	8
GO:0140640	catalytic activity, acting on a nucleic acid	2	8
GO:0140657	ATP-dependent activity	1	8
GO:1901265	nucleoside phosphate binding	3	8
GO:1901363	heterocyclic compound binding	2	8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	290	294	PF00656	0.816
CLV_C14_Caspase3-7	80	84	PF00656	0.652
CLV_C14_Caspase3-7	912	916	PF00656	0.638
CLV_NRD_NRD_1	1146	1148	PF00675	0.584
CLV_NRD_NRD_1	1151	1153	PF00675	0.582
CLV_NRD_NRD_1	1157	1159	PF00675	0.573
CLV_NRD_NRD_1	1203	1205	PF00675	0.688
CLV_NRD_NRD_1	1206	1208	PF00675	0.672
CLV_NRD_NRD_1	217	219	PF00675	0.699
CLV_NRD_NRD_1	337	339	PF00675	0.572
CLV_NRD_NRD_1	551	553	PF00675	0.375
CLV_NRD_NRD_1	582	584	PF00675	0.375
CLV_NRD_NRD_1	620	622	PF00675	0.484
CLV_NRD_NRD_1	648	650	PF00675	0.458
CLV_NRD_NRD_1	735	737	PF00675	0.706
CLV_NRD_NRD_1	811	813	PF00675	0.526
CLV_NRD_NRD_1	838	840	PF00675	0.721
CLV_NRD_NRD_1	981	983	PF00675	0.509
CLV_PCSK_FUR_1	1204	1208	PF00082	0.701
CLV_PCSK_KEX2_1	1146	1148	PF00082	0.573
CLV_PCSK_KEX2_1	1151	1153	PF00082	0.595
CLV_PCSK_KEX2_1	1159	1161	PF00082	0.592
CLV_PCSK_KEX2_1	1167	1169	PF00082	0.534
CLV_PCSK_KEX2_1	1205	1207	PF00082	0.689
CLV_PCSK_KEX2_1	231	233	PF00082	0.788
CLV_PCSK_KEX2_1	316	318	PF00082	0.751
CLV_PCSK_KEX2_1	337	339	PF00082	0.531
CLV_PCSK_KEX2_1	551	553	PF00082	0.375
CLV_PCSK_KEX2_1	582	584	PF00082	0.375
CLV_PCSK_KEX2_1	620	622	PF00082	0.484
CLV_PCSK_KEX2_1	648	650	PF00082	0.458
CLV_PCSK_KEX2_1	734	736	PF00082	0.717
CLV_PCSK_KEX2_1	811	813	PF00082	0.526
CLV_PCSK_KEX2_1	838	840	PF00082	0.677
CLV_PCSK_KEX2_1	90	92	PF00082	0.759
CLV_PCSK_PC1ET2_1	1159	1161	PF00082	0.695
CLV_PCSK_PC1ET2_1	1167	1169	PF00082	0.552
CLV_PCSK_PC1ET2_1	1205	1207	PF00082	0.689
CLV_PCSK_PC1ET2_1	231	233	PF00082	0.786
CLV_PCSK_PC1ET2_1	316	318	PF00082	0.746
CLV_PCSK_PC1ET2_1	90	92	PF00082	0.686
CLV_PCSK_PC7_1	1147	1153	PF00082	0.592
CLV_PCSK_PC7_1	86	92	PF00082	0.733
CLV_PCSK_SKI1_1	1154	1158	PF00082	0.600
CLV_PCSK_SKI1_1	1191	1195	PF00082	0.643
CLV_PCSK_SKI1_1	228	232	PF00082	0.755
CLV_PCSK_SKI1_1	338	342	PF00082	0.511
CLV_PCSK_SKI1_1	467	471	PF00082	0.567
CLV_PCSK_SKI1_1	501	505	PF00082	0.375
CLV_PCSK_SKI1_1	506	510	PF00082	0.375
CLV_PCSK_SKI1_1	571	575	PF00082	0.429
CLV_PCSK_SKI1_1	921	925	PF00082	0.570
CLV_PCSK_SKI1_1	959	963	PF00082	0.446
DEG_Nend_UBRbox_2	1	3	PF02207	0.569
DEG_SPOP_SBC_1	844	848	PF00917	0.717
DOC_CDC14_PxL_1	772	780	PF14671	0.477
DOC_CKS1_1	944	949	PF01111	0.631
DOC_CYCLIN_RxL_1	90	101	PF00134	0.712
DOC_CYCLIN_yClb5_NLxxxL_5	373	379	PF00134	0.618
DOC_CYCLIN_yClb5_NLxxxL_5	961	970	PF00134	0.530
DOC_CYCLIN_yCln2_LP_2	778	781	PF00134	0.597
DOC_CYCLIN_yCln2_LP_2	948	954	PF00134	0.518
DOC_MAPK_DCC_7	794	803	PF00069	0.574
DOC_MAPK_DCC_7	870	879	PF00069	0.597
DOC_MAPK_gen_1	1098	1107	PF00069	0.461
DOC_MAPK_gen_1	337	347	PF00069	0.580
DOC_MAPK_gen_1	582	589	PF00069	0.406
DOC_MAPK_gen_1	620	628	PF00069	0.444
DOC_MAPK_gen_1	648	656	PF00069	0.524
DOC_MAPK_gen_1	90	97	PF00069	0.715
DOC_MAPK_HePTP_8	579	591	PF00069	0.411
DOC_MAPK_JIP1_4	950	956	PF00069	0.578
DOC_MAPK_MEF2A_6	348	357	PF00069	0.496
DOC_MAPK_MEF2A_6	514	521	PF00069	0.356
DOC_MAPK_MEF2A_6	582	591	PF00069	0.406
DOC_MAPK_MEF2A_6	620	628	PF00069	0.497
DOC_MAPK_MEF2A_6	648	656	PF00069	0.524
DOC_MAPK_MEF2A_6	794	803	PF00069	0.603
DOC_MAPK_RevD_3	799	812	PF00069	0.551
DOC_PP1_RVXF_1	381	387	PF00149	0.500
DOC_PP1_RVXF_1	634	641	PF00149	0.534
DOC_PP1_RVXF_1	656	663	PF00149	0.622
DOC_PP2B_LxvP_1	300	303	PF13499	0.598
DOC_PP2B_LxvP_1	312	315	PF13499	0.507
DOC_PP2B_LxvP_1	654	657	PF13499	0.528
DOC_PP2B_LxvP_1	778	781	PF13499	0.597
DOC_PP4_FxxP_1	1016	1019	PF00568	0.514
DOC_USP7_MATH_1	104	108	PF00917	0.698
DOC_USP7_MATH_1	186	190	PF00917	0.738
DOC_USP7_MATH_1	211	215	PF00917	0.741
DOC_USP7_MATH_1	237	241	PF00917	0.746
DOC_USP7_MATH_1	279	283	PF00917	0.835
DOC_USP7_MATH_1	324	328	PF00917	0.625
DOC_USP7_MATH_1	456	460	PF00917	0.702
DOC_USP7_MATH_1	712	716	PF00917	0.810
DOC_USP7_MATH_1	77	81	PF00917	0.645
DOC_USP7_MATH_1	843	847	PF00917	0.750
DOC_USP7_MATH_1	850	854	PF00917	0.687
DOC_USP7_MATH_2	411	417	PF00917	0.547
DOC_USP7_UBL2_3	800	804	PF12436	0.559
DOC_WW_Pin1_4	1206	1211	PF00397	0.723
DOC_WW_Pin1_4	1216	1221	PF00397	0.672
DOC_WW_Pin1_4	34	39	PF00397	0.746
DOC_WW_Pin1_4	443	448	PF00397	0.733
DOC_WW_Pin1_4	541	546	PF00397	0.499
DOC_WW_Pin1_4	722	727	PF00397	0.796
DOC_WW_Pin1_4	785	790	PF00397	0.461
DOC_WW_Pin1_4	943	948	PF00397	0.559
LIG_14-3-3_CanoR_1	1146	1150	PF00244	0.616
LIG_14-3-3_CanoR_1	1151	1157	PF00244	0.611
LIG_14-3-3_CanoR_1	1204	1210	PF00244	0.704
LIG_14-3-3_CanoR_1	144	152	PF00244	0.643
LIG_14-3-3_CanoR_1	250	257	PF00244	0.846
LIG_14-3-3_CanoR_1	383	387	PF00244	0.514
LIG_14-3-3_CanoR_1	401	408	PF00244	0.502
LIG_14-3-3_CanoR_1	717	726	PF00244	0.731
LIG_14-3-3_CanoR_1	823	828	PF00244	0.725
LIG_14-3-3_CanoR_1	831	837	PF00244	0.657
LIG_Actin_WH2_2	566	584	PF00022	0.375
LIG_APCC_ABBA_1	699	704	PF00400	0.753
LIG_APCC_ABBA_1	923	928	PF00400	0.650
LIG_BIR_III_2	71	75	PF00653	0.601
LIG_BRCT_BRCA1_1	598	602	PF00533	0.419
LIG_BRCT_BRCA1_1	615	619	PF00533	0.326
LIG_BRCT_BRCA1_1	658	662	PF00533	0.627
LIG_BRCT_BRCA1_1	852	856	PF00533	0.767
LIG_CSL_BTD_1	786	789	PF09270	0.528
LIG_CtBP_PxDLS_1	1057	1061	PF00389	0.464
LIG_CtBP_PxDLS_1	780	784	PF00389	0.601
LIG_FHA_1	1035	1041	PF00498	0.467
LIG_FHA_1	126	132	PF00498	0.678
LIG_FHA_1	138	144	PF00498	0.653
LIG_FHA_1	204	210	PF00498	0.695
LIG_FHA_1	307	313	PF00498	0.618
LIG_FHA_1	334	340	PF00498	0.491
LIG_FHA_1	347	353	PF00498	0.512
LIG_FHA_1	359	365	PF00498	0.609
LIG_FHA_1	522	528	PF00498	0.375
LIG_FHA_1	613	619	PF00498	0.552
LIG_FHA_1	722	728	PF00498	0.803
LIG_FHA_1	759	765	PF00498	0.625
LIG_FHA_1	788	794	PF00498	0.429
LIG_FHA_1	803	809	PF00498	0.482
LIG_FHA_1	90	96	PF00498	0.685
LIG_FHA_2	244	250	PF00498	0.805
LIG_FHA_2	365	371	PF00498	0.553
LIG_FHA_2	405	411	PF00498	0.549
LIG_FHA_2	439	445	PF00498	0.755
LIG_FHA_2	468	474	PF00498	0.532
LIG_FHA_2	750	756	PF00498	0.522
LIG_FHA_2	757	763	PF00498	0.505
LIG_FHA_2	930	936	PF00498	0.500
LIG_Integrin_isoDGR_2	1027	1029	PF01839	0.572
LIG_IRF3_LxIS_1	537	544	PF10401	0.499
LIG_LIR_Apic_2	1013	1019	PF02991	0.520
LIG_LIR_Gen_1	208	217	PF02991	0.751
LIG_LIR_Gen_1	556	566	PF02991	0.416
LIG_LIR_Gen_1	572	581	PF02991	0.283
LIG_LIR_Gen_1	599	610	PF02991	0.380
LIG_LIR_Nem_3	1008	1012	PF02991	0.450
LIG_LIR_Nem_3	208	213	PF02991	0.753
LIG_LIR_Nem_3	385	389	PF02991	0.503
LIG_LIR_Nem_3	51	57	PF02991	0.725
LIG_LIR_Nem_3	556	561	PF02991	0.416
LIG_LIR_Nem_3	572	577	PF02991	0.283
LIG_LIR_Nem_3	599	605	PF02991	0.407
LIG_LIR_Nem_3	728	733	PF02991	0.600
LIG_LIR_Nem_3	899	903	PF02991	0.527
LIG_LYPXL_S_1	874	878	PF13949	0.585
LIG_MYND_1	776	780	PF01753	0.591
LIG_PCNA_yPIPBox_3	679	690	PF02747	0.627
LIG_PCNA_yPIPBox_3	972	983	PF02747	0.488
LIG_Pex14_1	787	791	PF04695	0.448
LIG_Pex14_2	619	623	PF04695	0.455
LIG_PTB_Apo_2	1042	1049	PF02174	0.516
LIG_SH2_CRK	558	562	PF00017	0.429
LIG_SH2_NCK_1	210	214	PF00017	0.679
LIG_SH2_SRC	210	213	PF00017	0.682
LIG_SH2_STAP1	1006	1010	PF00017	0.427
LIG_SH2_STAP1	1062	1066	PF00017	0.413
LIG_SH2_STAP1	139	143	PF00017	0.634
LIG_SH2_STAP1	558	562	PF00017	0.429
LIG_SH2_STAT5	1009	1012	PF00017	0.441
LIG_SH2_STAT5	1093	1096	PF00017	0.415
LIG_SH2_STAT5	1164	1167	PF00017	0.608
LIG_SH2_STAT5	139	142	PF00017	0.621
LIG_SH2_STAT5	492	495	PF00017	0.375
LIG_SH2_STAT5	535	538	PF00017	0.193
LIG_SH2_STAT5	791	794	PF00017	0.495
LIG_SH2_STAT5	813	816	PF00017	0.446
LIG_SH2_STAT5	818	821	PF00017	0.535
LIG_SH2_STAT5	903	906	PF00017	0.588
LIG_SH2_STAT5	992	995	PF00017	0.501
LIG_SH3_3	1016	1022	PF00018	0.477
LIG_SH3_3	1029	1035	PF00018	0.385
LIG_SH3_3	1096	1102	PF00018	0.444
LIG_SH3_3	282	288	PF00018	0.762
LIG_SH3_3	381	387	PF00018	0.517
LIG_SH3_3	405	411	PF00018	0.641
LIG_SH3_3	71	77	PF00018	0.682
LIG_SH3_3	723	729	PF00018	0.777
LIG_SH3_3	870	876	PF00018	0.539
LIG_SH3_3	883	889	PF00018	0.362
LIG_SUMO_SIM_anti_2	349	354	PF11976	0.538
LIG_SUMO_SIM_anti_2	559	565	PF11976	0.375
LIG_SUMO_SIM_par_1	465	473	PF11976	0.609
LIG_SUMO_SIM_par_1	559	565	PF11976	0.375
LIG_TRAF2_1	200	203	PF00917	0.678
LIG_TRAF2_1	39	42	PF00917	0.702
LIG_UBA3_1	460	467	PF00899	0.709
LIG_UBA3_1	504	509	PF00899	0.429
LIG_WRC_WIRS_1	1107	1112	PF05994	0.534
LIG_WRC_WIRS_1	771	776	PF05994	0.520
LIG_WRC_WIRS_1	803	808	PF05994	0.588
MOD_CDK_SPxK_1	1206	1212	PF00069	0.672
MOD_CDK_SPxxK_3	943	950	PF00069	0.625
MOD_CK1_1	1106	1112	PF00069	0.599
MOD_CK1_1	1174	1180	PF00069	0.651
MOD_CK1_1	189	195	PF00069	0.751
MOD_CK1_1	346	352	PF00069	0.543
MOD_CK1_1	404	410	PF00069	0.556
MOD_CK1_1	443	449	PF00069	0.719
MOD_CK1_1	567	573	PF00069	0.410
MOD_CK1_1	691	697	PF00069	0.662
MOD_CK1_1	715	721	PF00069	0.808
MOD_CK1_1	826	832	PF00069	0.751
MOD_CK1_1	846	852	PF00069	0.459
MOD_CK1_1	868	874	PF00069	0.570
MOD_CK1_1	974	980	PF00069	0.499
MOD_CK2_1	150	156	PF00069	0.751
MOD_CK2_1	197	203	PF00069	0.709
MOD_CK2_1	249	255	PF00069	0.739
MOD_CK2_1	364	370	PF00069	0.498
MOD_CK2_1	438	444	PF00069	0.720
MOD_CK2_1	456	462	PF00069	0.780
MOD_CK2_1	749	755	PF00069	0.494
MOD_CK2_1	756	762	PF00069	0.477
MOD_CK2_1	863	869	PF00069	0.651
MOD_GlcNHglycan	1199	1202	PF01048	0.718
MOD_GlcNHglycan	133	136	PF01048	0.663
MOD_GlcNHglycan	164	167	PF01048	0.716
MOD_GlcNHglycan	186	189	PF01048	0.744
MOD_GlcNHglycan	281	284	PF01048	0.837
MOD_GlcNHglycan	30	34	PF01048	0.759
MOD_GlcNHglycan	326	329	PF01048	0.698
MOD_GlcNHglycan	4	7	PF01048	0.689
MOD_GlcNHglycan	415	418	PF01048	0.587
MOD_GlcNHglycan	447	450	PF01048	0.802
MOD_GlcNHglycan	598	601	PF01048	0.429
MOD_GlcNHglycan	719	722	PF01048	0.792
MOD_GlcNHglycan	832	835	PF01048	0.790
MOD_GlcNHglycan	852	855	PF01048	0.439
MOD_GSK3_1	1043	1050	PF00069	0.576
MOD_GSK3_1	1106	1113	PF00069	0.532
MOD_GSK3_1	1141	1148	PF00069	0.598
MOD_GSK3_1	452	459	PF00069	0.785
MOD_GSK3_1	688	695	PF00069	0.692
MOD_GSK3_1	702	709	PF00069	0.808
MOD_GSK3_1	717	724	PF00069	0.587
MOD_GSK3_1	779	786	PF00069	0.537
MOD_GSK3_1	822	829	PF00069	0.598
MOD_GSK3_1	846	853	PF00069	0.695
MOD_LATS_1	1203	1209	PF00433	0.658
MOD_N-GLC_1	854	859	PF02516	0.718
MOD_N-GLC_1	971	976	PF02516	0.481
MOD_NEK2_1	1080	1085	PF00069	0.448
MOD_NEK2_1	1105	1110	PF00069	0.461
MOD_NEK2_1	1124	1129	PF00069	0.443
MOD_NEK2_1	116	121	PF00069	0.669
MOD_NEK2_1	184	189	PF00069	0.671
MOD_NEK2_1	421	426	PF00069	0.523
MOD_NEK2_1	613	618	PF00069	0.470
MOD_NEK2_1	706	711	PF00069	0.601
MOD_NEK2_1	783	788	PF00069	0.565
MOD_NEK2_1	937	942	PF00069	0.586
MOD_NEK2_1	961	966	PF00069	0.489
MOD_NEK2_2	1062	1067	PF00069	0.422
MOD_NEK2_2	238	243	PF00069	0.619
MOD_NEK2_2	343	348	PF00069	0.587
MOD_NEK2_2	533	538	PF00069	0.429
MOD_NEK2_2	712	717	PF00069	0.812
MOD_PIKK_1	1129	1135	PF00454	0.602
MOD_PIKK_1	186	192	PF00454	0.741
MOD_PIKK_1	527	533	PF00454	0.429
MOD_PIKK_1	715	721	PF00454	0.765
MOD_PIKK_1	823	829	PF00454	0.692
MOD_PIKK_1	937	943	PF00454	0.464
MOD_PK_1	735	741	PF00069	0.658
MOD_PK_1	999	1005	PF00069	0.585
MOD_PKA_1	1152	1158	PF00069	0.630
MOD_PKA_1	1205	1211	PF00069	0.708
MOD_PKA_1	316	322	PF00069	0.713
MOD_PKA_1	735	741	PF00069	0.658
MOD_PKA_2	1145	1151	PF00069	0.697
MOD_PKA_2	1197	1203	PF00069	0.708
MOD_PKA_2	1205	1211	PF00069	0.645
MOD_PKA_2	249	255	PF00069	0.808
MOD_PKA_2	316	322	PF00069	0.713
MOD_PKA_2	358	364	PF00069	0.597
MOD_PKA_2	382	388	PF00069	0.528
MOD_PKA_2	413	419	PF00069	0.547
MOD_PKA_2	735	741	PF00069	0.739
MOD_PKA_2	822	828	PF00069	0.756
MOD_PKA_2	830	836	PF00069	0.657
MOD_Plk_1	1080	1086	PF00069	0.419
MOD_Plk_1	1124	1130	PF00069	0.440
MOD_Plk_1	196	202	PF00069	0.796
MOD_Plk_1	404	410	PF00069	0.556
MOD_Plk_1	553	559	PF00069	0.402
MOD_Plk_1	564	570	PF00069	0.334
MOD_Plk_1	712	718	PF00069	0.811
MOD_Plk_1	868	874	PF00069	0.546
MOD_Plk_1	935	941	PF00069	0.557
MOD_Plk_1	999	1005	PF00069	0.569
MOD_Plk_2-3	197	203	PF00069	0.785
MOD_Plk_2-3	249	255	PF00069	0.729
MOD_Plk_2-3	267	273	PF00069	0.637
MOD_Plk_2-3	554	560	PF00069	0.429
MOD_Plk_2-3	66	72	PF00069	0.713
MOD_Plk_4	1070	1076	PF00069	0.468
MOD_Plk_4	1110	1116	PF00069	0.521
MOD_Plk_4	1152	1158	PF00069	0.656
MOD_Plk_4	456	462	PF00069	0.720
MOD_Plk_4	488	494	PF00069	0.375
MOD_Plk_4	499	505	PF00069	0.375
MOD_Plk_4	564	570	PF00069	0.375
MOD_Plk_4	614	620	PF00069	0.542
MOD_Plk_4	779	785	PF00069	0.522
MOD_Plk_4	787	793	PF00069	0.402
MOD_Plk_4	974	980	PF00069	0.499
MOD_Plk_4	999	1005	PF00069	0.585
MOD_ProDKin_1	1206	1212	PF00069	0.726
MOD_ProDKin_1	1216	1222	PF00069	0.673
MOD_ProDKin_1	34	40	PF00069	0.746
MOD_ProDKin_1	443	449	PF00069	0.734
MOD_ProDKin_1	541	547	PF00069	0.499
MOD_ProDKin_1	722	728	PF00069	0.796
MOD_ProDKin_1	785	791	PF00069	0.456
MOD_ProDKin_1	943	949	PF00069	0.555
MOD_SUMO_for_1	1010	1013	PF00179	0.515
MOD_SUMO_rev_2	1184	1193	PF00179	0.642
MOD_SUMO_rev_2	459	469	PF00179	0.702
TRG_DiLeu_BaEn_1	326	331	PF01217	0.610
TRG_DiLeu_BaEn_3	895	901	PF01217	0.542
TRG_DiLeu_BaEn_4	196	202	PF01217	0.726
TRG_DiLeu_BaLyEn_6	1183	1188	PF01217	0.544
TRG_DiLeu_BaLyEn_6	398	403	PF01217	0.536
TRG_DiLeu_BaLyEn_6	609	614	PF01217	0.516
TRG_ENDOCYTIC_2	1093	1096	PF00928	0.415
TRG_ENDOCYTIC_2	210	213	PF00928	0.682
TRG_ENDOCYTIC_2	332	335	PF00928	0.486
TRG_ENDOCYTIC_2	396	399	PF00928	0.487
TRG_ENDOCYTIC_2	54	57	PF00928	0.725
TRG_ENDOCYTIC_2	558	561	PF00928	0.429
TRG_ENDOCYTIC_2	875	878	PF00928	0.467
TRG_ER_diArg_1	1145	1147	PF00400	0.611
TRG_ER_diArg_1	1157	1160	PF00400	0.649
TRG_ER_diArg_1	1204	1207	PF00400	0.661
TRG_ER_diArg_1	143	146	PF00400	0.613
TRG_ER_diArg_1	337	339	PF00400	0.572
TRG_ER_diArg_1	581	583	PF00400	0.375
TRG_ER_diArg_1	619	621	PF00400	0.468
TRG_ER_diArg_1	647	649	PF00400	0.444
TRG_ER_diArg_1	733	736	PF00400	0.718
TRG_ER_diArg_1	810	812	PF00400	0.525
TRG_ER_diArg_1	837	839	PF00400	0.481
TRG_ER_diArg_1	884	887	PF00400	0.441
TRG_ER_diArg_1	918	921	PF00400	0.535
TRG_NES_CRM1_1	1070	1081	PF08389	0.452
TRG_NLS_Bipartite_1	1151	1170	PF00514	0.616
TRG_NLS_Bipartite_1	218	235	PF00514	0.821
TRG_NLS_MonoCore_2	1203	1208	PF00514	0.656
TRG_NLS_MonoExtC_3	227	232	PF00514	0.828
TRG_NLS_MonoExtN_4	1151	1156	PF00514	0.655
TRG_NLS_MonoExtN_4	1204	1209	PF00514	0.703
TRG_NLS_MonoExtN_4	225	232	PF00514	0.829
TRG_Pf-PMV_PEXEL_1	1186	1190	PF00026	0.545
TRG_Pf-PMV_PEXEL_1	17	21	PF00026	0.767
TRG_Pf-PMV_PEXEL_1	373	378	PF00026	0.559
TRG_Pf-PMV_PEXEL_1	401	405	PF00026	0.552
TRG_Pf-PMV_PEXEL_1	506	510	PF00026	0.429
TRG_Pf-PMV_PEXEL_1	571	575	PF00026	0.429
TRG_Pf-PMV_PEXEL_1	93	98	PF00026	0.719
TRG_Pf-PMV_PEXEL_1	982	987	PF00026	0.509

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IIS5	Leptomonas seymouri	63%	89%
A0A3R7MZY3	Trypanosoma rangeli	44%	100%
A4H6E9	Leishmania braziliensis	79%	97%
A4HUU3	Leishmania infantum	99%	100%
E9ANH8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
Q4QH48	Leishmania major	93%	100%