LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7WRA2_LEIDO
TriTrypDb:
LdBPK_101140.1 * , LdCL_100018300 , LDHU3_10.1490
Length:
322

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 5
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WRA2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WRA2

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 122 126 PF00656 0.654
CLV_NRD_NRD_1 146 148 PF00675 0.605
CLV_PCSK_KEX2_1 146 148 PF00082 0.605
CLV_PCSK_KEX2_1 228 230 PF00082 0.543
CLV_PCSK_PC1ET2_1 228 230 PF00082 0.543
CLV_PCSK_SKI1_1 214 218 PF00082 0.568
DEG_Nend_UBRbox_1 1 4 PF02207 0.542
DOC_MAPK_gen_1 195 204 PF00069 0.519
DOC_MAPK_RevD_3 215 229 PF00069 0.555
DOC_PP4_FxxP_1 21 24 PF00568 0.699
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P5X0 Leptomonas seymouri 48% 95%
A0A1X0NS26 Trypanosomatidae 31% 100%
A0A422NGN0 Trypanosoma rangeli 33% 100%
A4H694 Leishmania braziliensis 81% 99%
A4HUL7 Leishmania infantum 99% 100%
C9ZVP4 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 27% 100%
E9ANB6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 93% 100%
Q4QHA8 Leishmania major 91% 100%
V5DKP6 Trypanosoma cruzi 34% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS