Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania donovani

UniProt:

A0A3S7WR93_LEIDO

TriTrypDb:

LdCL_100016900 , LDHU3_10.1340

Length:

395

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 1, no: 1
NetGPI	no	yes: 0, no: 2

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	3
GO:0110165	cellular anatomical entity	1	3

Expansion

Sequence features

A0A3S7WR93

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WR93

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	170	172	PF00675	0.434
CLV_NRD_NRD_1	216	218	PF00675	0.404
CLV_NRD_NRD_1	291	293	PF00675	0.425
CLV_PCSK_KEX2_1	170	172	PF00082	0.434
CLV_PCSK_KEX2_1	216	218	PF00082	0.440
CLV_PCSK_KEX2_1	291	293	PF00082	0.425
CLV_PCSK_KEX2_1	393	395	PF00082	0.738
CLV_PCSK_PC1ET2_1	393	395	PF00082	0.738
CLV_PCSK_SKI1_1	136	140	PF00082	0.644
CLV_PCSK_SKI1_1	378	382	PF00082	0.678
DEG_Nend_Nbox_1	1	3	PF02207	0.446
DEG_ODPH_VHL_1	32	43	PF01847	0.489
DOC_CKS1_1	250	255	PF01111	0.451
DOC_MAPK_FxFP_2	126	129	PF00069	0.495
DOC_MAPK_gen_1	167	176	PF00069	0.632
DOC_MAPK_MEF2A_6	54	63	PF00069	0.443
DOC_MAPK_MEF2A_6	72	80	PF00069	0.303
DOC_PP2B_LxvP_1	347	350	PF13499	0.504
DOC_PP4_FxxP_1	126	129	PF00568	0.495
DOC_USP7_MATH_1	129	133	PF00917	0.486
DOC_USP7_MATH_1	134	138	PF00917	0.399
DOC_USP7_MATH_1	266	270	PF00917	0.429
DOC_USP7_MATH_1	350	354	PF00917	0.518
DOC_WW_Pin1_4	20	25	PF00397	0.485
DOC_WW_Pin1_4	249	254	PF00397	0.570
DOC_WW_Pin1_4	360	365	PF00397	0.494
LIG_14-3-3_CanoR_1	191	197	PF00244	0.696
LIG_14-3-3_CanoR_1	211	219	PF00244	0.432
LIG_14-3-3_CanoR_1	292	301	PF00244	0.631
LIG_Actin_WH2_2	272	290	PF00022	0.429
LIG_BRCT_BRCA1_1	107	111	PF00533	0.429
LIG_BRCT_BRCA1_1	260	264	PF00533	0.437
LIG_BRCT_BRCA1_1	268	272	PF00533	0.317
LIG_BRCT_BRCA1_1	297	301	PF00533	0.550
LIG_FHA_1	15	21	PF00498	0.498
LIG_FHA_1	191	197	PF00498	0.682
LIG_FHA_1	250	256	PF00498	0.452
LIG_FHA_1	282	288	PF00498	0.522
LIG_FHA_1	323	329	PF00498	0.455
LIG_FHA_1	86	92	PF00498	0.429
LIG_LIR_Apic_2	127	131	PF02991	0.501
LIG_LIR_Apic_2	29	34	PF02991	0.482
LIG_LIR_Gen_1	108	119	PF02991	0.429
LIG_LIR_Gen_1	243	251	PF02991	0.429
LIG_LIR_Gen_1	269	280	PF02991	0.429
LIG_LIR_Gen_1	314	324	PF02991	0.583
LIG_LIR_Nem_3	108	114	PF02991	0.429
LIG_LIR_Nem_3	243	247	PF02991	0.429
LIG_LIR_Nem_3	261	267	PF02991	0.169
LIG_LIR_Nem_3	269	275	PF02991	0.317
LIG_LIR_Nem_3	314	320	PF02991	0.429
LIG_LIR_Nem_3	346	351	PF02991	0.504
LIG_LIR_Nem_3	371	375	PF02991	0.432
LIG_LIR_Nem_3	9	15	PF02991	0.493
LIG_PALB2_WD40_1	98	106	PF16756	0.503
LIG_Pex14_2	111	115	PF04695	0.429
LIG_SH2_CRK	95	99	PF00017	0.640
LIG_SH2_GRB2like	317	320	PF00017	0.586
LIG_SH2_GRB2like	55	58	PF00017	0.512
LIG_SH2_PTP2	15	18	PF00017	0.477
LIG_SH2_PTP2	31	34	PF00017	0.367
LIG_SH2_PTP2	317	320	PF00017	0.586
LIG_SH2_SRC	317	320	PF00017	0.586
LIG_SH2_SRC	55	58	PF00017	0.496
LIG_SH2_STAP1	100	104	PF00017	0.429
LIG_SH2_STAT3	256	259	PF00017	0.436
LIG_SH2_STAT5	15	18	PF00017	0.440
LIG_SH2_STAT5	219	222	PF00017	0.634
LIG_SH2_STAT5	293	296	PF00017	0.622
LIG_SH2_STAT5	31	34	PF00017	0.491
LIG_SH2_STAT5	317	320	PF00017	0.522
LIG_SH2_STAT5	375	378	PF00017	0.492
LIG_SH3_2	131	136	PF14604	0.461
LIG_SH3_3	128	134	PF00018	0.478
LIG_SH3_3	142	148	PF00018	0.233
LIG_SH3_3	247	253	PF00018	0.557
LIG_SH3_3	58	64	PF00018	0.525
LIG_SH3_3	77	83	PF00018	0.175
LIG_SUMO_SIM_anti_2	307	314	PF11976	0.365
LIG_SUMO_SIM_par_1	237	243	PF11976	0.429
LIG_SUMO_SIM_par_1	82	88	PF11976	0.429
LIG_TRFH_1	117	121	PF08558	0.429
LIG_TYR_ITIM	315	320	PF00017	0.429
LIG_WRC_WIRS_1	241	246	PF05994	0.429
LIG_WRC_WIRS_1	27	32	PF05994	0.477
LIG_WW_1	253	256	PF00397	0.462
MOD_CDC14_SPxK_1	363	366	PF00782	0.482
MOD_CDK_SPxK_1	360	366	PF00069	0.493
MOD_CK1_1	132	138	PF00069	0.476
MOD_CK1_1	23	29	PF00069	0.485
MOD_CK2_1	350	356	PF00069	0.482
MOD_Cter_Amidation	289	292	PF01082	0.419
MOD_GlcNHglycan	213	216	PF01048	0.411
MOD_GlcNHglycan	297	300	PF01048	0.310
MOD_GSK3_1	186	193	PF00069	0.667
MOD_GSK3_1	379	386	PF00069	0.502
MOD_N-GLC_1	322	327	PF02516	0.674
MOD_N-GLC_1	373	378	PF02516	0.655
MOD_NEK2_1	106	111	PF00069	0.436
MOD_NEK2_1	240	245	PF00069	0.429
MOD_NEK2_1	258	263	PF00069	0.255
MOD_NEK2_1	275	280	PF00069	0.396
MOD_NEK2_1	355	360	PF00069	0.485
MOD_NEK2_1	383	388	PF00069	0.412
MOD_NEK2_1	6	11	PF00069	0.491
MOD_NEK2_1	84	89	PF00069	0.333
MOD_OFUCOSY	330	335	PF10250	0.619
MOD_PIKK_1	186	192	PF00454	0.678
MOD_PIKK_1	373	379	PF00454	0.490
MOD_PKA_2	190	196	PF00069	0.695
MOD_PKB_1	184	192	PF00069	0.675
MOD_Plk_1	322	328	PF00069	0.475
MOD_Plk_1	355	361	PF00069	0.525
MOD_Plk_4	106	112	PF00069	0.429
MOD_Plk_4	134	140	PF00069	0.412
MOD_Plk_4	23	29	PF00069	0.480
MOD_Plk_4	240	246	PF00069	0.429
MOD_Plk_4	258	264	PF00069	0.251
MOD_Plk_4	268	274	PF00069	0.290
MOD_Plk_4	275	281	PF00069	0.192
MOD_Plk_4	282	288	PF00069	0.326
MOD_Plk_4	304	310	PF00069	0.365
MOD_Plk_4	311	317	PF00069	0.365
MOD_Plk_4	323	329	PF00069	0.431
MOD_Plk_4	343	349	PF00069	0.295
MOD_Plk_4	350	356	PF00069	0.470
MOD_ProDKin_1	20	26	PF00069	0.483
MOD_ProDKin_1	249	255	PF00069	0.569
MOD_ProDKin_1	360	366	PF00069	0.493
TRG_DiLeu_BaEn_2	174	180	PF01217	0.629
TRG_DiLeu_BaEn_2	35	41	PF01217	0.491
TRG_ENDOCYTIC_2	100	103	PF00928	0.479
TRG_ENDOCYTIC_2	15	18	PF00928	0.477
TRG_ENDOCYTIC_2	317	320	PF00928	0.586
TRG_ENDOCYTIC_2	46	49	PF00928	0.488
TRG_ER_diArg_1	169	171	PF00400	0.641
TRG_ER_diArg_1	291	293	PF00400	0.625
TRG_NLS_MonoExtC_3	287	292	PF00514	0.623
TRG_Pf-PMV_PEXEL_1	167	172	PF00026	0.400
TRG_Pf-PMV_PEXEL_1	178	182	PF00026	0.425
TRG_Pf-PMV_PEXEL_1	366	371	PF00026	0.656

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0S4JP85	Bodo saltans	24%	95%