LeishMANIAdb
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Pteridine transporter, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Pteridine transporter, putative
Gene product:
folate/biopterin transporter, putative
Species:
Leishmania donovani
UniProt:
A0A3S7WR14_LEIDO
TriTrypDb:
LdBPK_100370.1 , LdCL_100009100 , LDHU3_10.0540
Length:
686

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 9
Silverman et al. no yes: 0
Pissara et al. no yes: 52
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 6
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 6
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 70
NetGPI no yes: 0, no: 70
Cellular components
TermNameLevelCount
GO:0005737 cytoplasm 2 6
GO:0005886 plasma membrane 3 1
GO:0016020 membrane 2 71
GO:0110165 cellular anatomical entity 1 71
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Expansion

Sequence features

A0A3S7WR14
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WR14

Function

Biological processes
TermNameLevelCount
GO:0006810 transport 3 1
GO:0015877 biopterin transport 5 1
GO:0051179 localization 1 1
GO:0051234 establishment of localization 2 1
GO:0071702 organic substance transport 4 1
GO:0071705 nitrogen compound transport 4 1
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Molecular functions
TermNameLevelCount
GO:0005215 transporter activity 1 1
GO:0015224 biopterin transmembrane transporter activity 3 1
GO:0022857 transmembrane transporter activity 2 1
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 273 275 PF00675 0.342
CLV_NRD_NRD_1 50 52 PF00675 0.423
CLV_PCSK_KEX2_1 135 137 PF00082 0.302
CLV_PCSK_KEX2_1 301 303 PF00082 0.424
CLV_PCSK_KEX2_1 50 52 PF00082 0.456
CLV_PCSK_KEX2_1 521 523 PF00082 0.526
CLV_PCSK_KEX2_1 525 527 PF00082 0.526
CLV_PCSK_PC1ET2_1 135 137 PF00082 0.302
CLV_PCSK_PC1ET2_1 301 303 PF00082 0.424
CLV_PCSK_PC1ET2_1 521 523 PF00082 0.526
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P2U2 Leptomonas seymouri 48% 97%
A0A0N1HY49 Leptomonas seymouri 46% 100%
A0A0N1HZ06 Leptomonas seymouri 35% 100%
A0A0N1IHL1 Leptomonas seymouri 40% 96%
A0A0N1PAY4 Leptomonas seymouri 46% 78%
A0A0N1PB77 Leptomonas seymouri 35% 100%
A0A0N1PBZ2 Leptomonas seymouri 67% 100%
A0A0N1PCC1 Leptomonas seymouri 43% 100%
A0A381MBI0 Leishmania infantum 45% 100%
A0A3Q8I8X7 Leishmania donovani 45% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS