LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7WQX5_LEIDO
TriTrypDb:
LdBPK_091590.1 * , LdCL_090022300 , LDHU3_09.1860
Length:
121

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WQX5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WQX5

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 14 16 PF00675 0.466
CLV_NRD_NRD_1 35 37 PF00675 0.526
CLV_NRD_NRD_1 5 7 PF00675 0.547
CLV_PCSK_FUR_1 12 16 PF00082 0.483
CLV_PCSK_KEX2_1 14 16 PF00082 0.466
CLV_PCSK_KEX2_1 45 47 PF00082 0.511
CLV_PCSK_KEX2_1 5 7 PF00082 0.547
CLV_PCSK_PC1ET2_1 45 47 PF00082 0.564
CLV_PCSK_SKI1_1 110 114 PF00082 0.521
CLV_PCSK_SKI1_1 14 18 PF00082 0.461
CLV_PCSK_SKI1_1 42 46 PF00082 0.554
CLV_PCSK_SKI1_1 57 61 PF00082 0.565
DEG_APCC_DBOX_1 109 117 PF00400 0.568
DEG_Nend_UBRbox_1 1 4 PF02207 0.576
DOC_CYCLIN_yCln2_LP_2 81 87 PF00134 0.573
DOC_MAPK_gen_1 42 51 PF00069 0.578
DOC_USP7_MATH_1 7 11 PF00917 0.471
LIG_14-3-3_CanoR_1 96 106 PF00244 0.609
LIG_FHA_1 99 105 PF00498 0.548
LIG_Integrin_isoDGR_2 61 63 PF01839 0.547
LIG_NRP_CendR_1 119 121 PF00754 0.588
MOD_CK1_1 25 31 PF00069 0.571
MOD_CK1_1 97 103 PF00069 0.573
MOD_CK2_1 25 31 PF00069 0.483
MOD_CK2_1 7 13 PF00069 0.453
MOD_GSK3_1 94 101 PF00069 0.568
MOD_N-GLC_1 25 30 PF02516 0.523
MOD_NEK2_1 94 99 PF00069 0.592
MOD_NEK2_2 7 12 PF00069 0.485
MOD_PKA_2 7 13 PF00069 0.464
MOD_PKA_2 97 103 PF00069 0.607
MOD_PKB_1 96 104 PF00069 0.607
TRG_ER_diArg_1 116 119 PF00400 0.581
TRG_ER_diArg_1 14 16 PF00400 0.466
TRG_ER_diArg_1 4 6 PF00400 0.554
TRG_ER_diArg_1 95 98 PF00400 0.511
TRG_NLS_MonoExtC_3 35 40 PF00514 0.621
TRG_NLS_MonoExtN_4 33 40 PF00514 0.614
TRG_Pf-PMV_PEXEL_1 110 114 PF00026 0.555

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I1L1 Leptomonas seymouri 84% 100%
A0A0S4JCT2 Bodo saltans 52% 95%
A0A1X0NHV8 Trypanosomatidae 52% 94%
A0A3S5ISF1 Trypanosoma rangeli 58% 99%
A4H5X7 Leishmania braziliensis 94% 100%
A4HU73 Leishmania infantum 100% 100%
D0A9Q5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 56% 90%
E9AN03 Leishmania mexicana (strain MHOM/GT/2001/U1103) 97% 100%
Q4QHM5 Leishmania major 98% 100%
V5BI65 Trypanosoma cruzi 61% 99%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS