LeishMANIAdb
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Sulfurtransferase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Sulfurtransferase
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7WQX1_LEIDO
TriTrypDb:
LdBPK_091550.1 , LdCL_090021900 , LDHU3_09.1820
Length:
119

Annotations

Annotations by Jardim et al.

Carbohydrate metabolism, Sulfurtransferase

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. yes yes: 18
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WQX1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WQX1

Function

Could not find GO biological_process term for this entry.
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 8
GO:0004792 thiosulfate sulfurtransferase activity 5 8
GO:0016740 transferase activity 2 8
GO:0016782 transferase activity, transferring sulphur-containing groups 3 8
GO:0016783 sulfurtransferase activity 4 8

Putative motif mimicry

Leishmania From To Domain/Motif Score
DEG_Nend_UBRbox_3 1 3 PF02207 0.454
DOC_USP7_MATH_1 70 74 PF00917 0.484
DOC_USP7_MATH_1 92 96 PF00917 0.427
LIG_14-3-3_CanoR_1 3 7 PF00244 0.340
LIG_FHA_1 76 82 PF00498 0.488
LIG_FHA_2 55 61 PF00498 0.502
LIG_FHA_2 97 103 PF00498 0.471
LIG_GBD_Chelix_1 13 21 PF00786 0.335
LIG_LIR_Gen_1 5 14 PF02991 0.398
LIG_LIR_Gen_1 95 105 PF02991 0.436
LIG_LIR_Nem_3 95 101 PF02991 0.458
LIG_SH2_CRK 65 69 PF00017 0.502
LIG_SH2_GRB2like 98 101 PF00017 0.424
LIG_SH2_NCK_1 98 102 PF00017 0.424
LIG_SH2_STAT5 79 82 PF00017 0.436
LIG_SH2_STAT5 98 101 PF00017 0.436
LIG_SH3_3 40 46 PF00018 0.441
LIG_TRAF2_1 112 115 PF00917 0.580
MOD_CK1_1 96 102 PF00069 0.551
MOD_CK2_1 104 110 PF00069 0.439
MOD_CK2_1 54 60 PF00069 0.519
MOD_CMANNOS 108 111 PF00535 0.208
MOD_GlcNHglycan 17 20 PF01048 0.376
MOD_GlcNHglycan 65 68 PF01048 0.296
MOD_GlcNHglycan 95 98 PF01048 0.305
MOD_GSK3_1 92 99 PF00069 0.520
MOD_NEK2_1 93 98 PF00069 0.460
MOD_PKA_1 15 21 PF00069 0.321
MOD_PKA_1 63 69 PF00069 0.483
MOD_PKA_2 2 8 PF00069 0.542
MOD_SUMO_for_1 68 71 PF00179 0.502
TRG_ENDOCYTIC_2 6 9 PF00928 0.353
TRG_ENDOCYTIC_2 98 101 PF00928 0.452

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P899 Leptomonas seymouri 32% 91%
A0A0N0P8M5 Leptomonas seymouri 66% 100%
A0A0N1PG29 Leptomonas seymouri 34% 88%
A0A1X0NHS7 Trypanosomatidae 50% 100%
A0A1X0NIC3 Trypanosomatidae 49% 100%
A0A1X0NJI4 Trypanosomatidae 31% 87%
A0A1X0NJQ7 Trypanosomatidae 32% 82%
A0A3Q8I7K7 Leishmania donovani 31% 100%
A0A3R7LB88 Trypanosoma rangeli 51% 96%
A0A3R7MT99 Trypanosoma rangeli 37% 87%
A0A3R7P0U7 Trypanosoma rangeli 32% 82%
A0A3S7WQW6 Leishmania donovani 35% 79%
A4H5X2 Leishmania braziliensis 34% 100%
A4H5X3 Leishmania braziliensis 35% 79%
A4H5X4 Leishmania braziliensis 85% 100%
A4HU67 Leishmania infantum 31% 100%
A4HU68 Leishmania infantum 35% 79%
A4HU69 Leishmania infantum 100% 100%
D0A9P9 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 87%
D0A9Q0 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 36% 83%
E9AMZ7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 32% 100%
E9AMZ8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 33% 79%
E9AMZ9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 97% 100%
P22978 Drosophila melanogaster 42% 100%
Q08742 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 34% 80%
Q10215 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 40% 84%
Q12305 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 34% 86%
Q4QHM8 Leishmania major 93% 100%
Q4QHM9 Leishmania major 34% 79%
Q4QHN0 Leishmania major 31% 100%
Q8NFU3 Homo sapiens 40% 100%
Q9D0B5 Mus musculus 39% 76%
V5BI16 Trypanosoma cruzi 35% 73%
V5BMN5 Trypanosoma cruzi 35% 84%
V5BMN9 Trypanosoma cruzi 45% 96%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS