Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7WQV1_LEIDO

TriTrypDb:

LdBPK_091170.1 , LdCL_090018100 , LDHU3_09.1400

Length:

458

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WQV1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WQV1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	43	47	PF00656	0.590
CLV_NRD_NRD_1	185	187	PF00675	0.606
CLV_NRD_NRD_1	200	202	PF00675	0.521
CLV_NRD_NRD_1	221	223	PF00675	0.520
CLV_NRD_NRD_1	243	245	PF00675	0.513
CLV_NRD_NRD_1	276	278	PF00675	0.452
CLV_NRD_NRD_1	305	307	PF00675	0.581
CLV_NRD_NRD_1	341	343	PF00675	0.530
CLV_NRD_NRD_1	357	359	PF00675	0.706
CLV_NRD_NRD_1	38	40	PF00675	0.622
CLV_NRD_NRD_1	397	399	PF00675	0.686
CLV_NRD_NRD_1	424	426	PF00675	0.640
CLV_PCSK_FUR_1	183	187	PF00082	0.479
CLV_PCSK_KEX2_1	185	187	PF00082	0.598
CLV_PCSK_KEX2_1	200	202	PF00082	0.521
CLV_PCSK_KEX2_1	221	223	PF00082	0.523
CLV_PCSK_KEX2_1	243	245	PF00082	0.513
CLV_PCSK_KEX2_1	276	278	PF00082	0.532
CLV_PCSK_KEX2_1	305	307	PF00082	0.581
CLV_PCSK_KEX2_1	341	343	PF00082	0.530
CLV_PCSK_KEX2_1	357	359	PF00082	0.706
CLV_PCSK_KEX2_1	38	40	PF00082	0.679
CLV_PCSK_KEX2_1	396	398	PF00082	0.652
CLV_PCSK_SKI1_1	287	291	PF00082	0.536
CLV_Separin_Metazoa	422	426	PF03568	0.508
DEG_Nend_Nbox_1	1	3	PF02207	0.584
DEG_SPOP_SBC_1	154	158	PF00917	0.649
DOC_CKS1_1	67	72	PF01111	0.653
DOC_MAPK_gen_1	406	415	PF00069	0.578
DOC_PP2B_LxvP_1	118	121	PF13499	0.615
DOC_PP4_FxxP_1	149	152	PF00568	0.634
DOC_PP4_FxxP_1	330	333	PF00568	0.590
DOC_USP7_MATH_1	104	108	PF00917	0.621
DOC_USP7_MATH_1	109	113	PF00917	0.648
DOC_USP7_MATH_1	20	24	PF00917	0.604
DOC_USP7_MATH_1	248	252	PF00917	0.482
DOC_USP7_MATH_1	257	261	PF00917	0.427
DOC_USP7_MATH_1	289	293	PF00917	0.468
DOC_USP7_MATH_1	374	378	PF00917	0.727
DOC_WW_Pin1_4	150	155	PF00397	0.688
DOC_WW_Pin1_4	358	363	PF00397	0.738
DOC_WW_Pin1_4	370	375	PF00397	0.716
DOC_WW_Pin1_4	389	394	PF00397	0.813
DOC_WW_Pin1_4	398	403	PF00397	0.616
DOC_WW_Pin1_4	438	443	PF00397	0.600
DOC_WW_Pin1_4	66	71	PF00397	0.712
LIG_14-3-3_CanoR_1	139	144	PF00244	0.641
LIG_14-3-3_CanoR_1	162	167	PF00244	0.608
LIG_14-3-3_CanoR_1	185	191	PF00244	0.495
LIG_14-3-3_CanoR_1	200	206	PF00244	0.505
LIG_14-3-3_CanoR_1	221	226	PF00244	0.464
LIG_14-3-3_CanoR_1	357	362	PF00244	0.600
LIG_14-3-3_CanoR_1	38	44	PF00244	0.650
LIG_14-3-3_CanoR_1	388	393	PF00244	0.616
LIG_14-3-3_CanoR_1	396	402	PF00244	0.611
LIG_14-3-3_CanoR_1	446	454	PF00244	0.586
LIG_14-3-3_CanoR_1	5	11	PF00244	0.738
LIG_DLG_GKlike_1	164	171	PF00625	0.622
LIG_FHA_1	155	161	PF00498	0.745
LIG_FHA_1	186	192	PF00498	0.543
LIG_FHA_1	399	405	PF00498	0.622
LIG_FHA_1	446	452	PF00498	0.590
LIG_FHA_2	121	127	PF00498	0.740
LIG_FHA_2	225	231	PF00498	0.465
LIG_FHA_2	38	44	PF00498	0.651
LIG_FHA_2	382	388	PF00498	0.622
LIG_FHA_2	67	73	PF00498	0.669
LIG_IBAR_NPY_1	332	334	PF08397	0.585
LIG_LIR_Apic_2	146	152	PF02991	0.638
LIG_LIR_Apic_2	416	421	PF02991	0.547
LIG_NRP_CendR_1	455	458	PF00754	0.552
LIG_Pex14_2	56	60	PF04695	0.597
LIG_Rb_pABgroove_1	312	320	PF01858	0.455
LIG_RPA_C_Fungi	190	202	PF08784	0.518
LIG_SH2_NCK_1	216	220	PF00017	0.532
LIG_SH2_STAP1	318	322	PF00017	0.546
LIG_SH2_STAP1	334	338	PF00017	0.453
LIG_SH2_STAP1	343	347	PF00017	0.534
LIG_SH2_STAT3	242	245	PF00017	0.514
LIG_SH2_STAT5	216	219	PF00017	0.532
LIG_SH2_STAT5	274	277	PF00017	0.453
LIG_SH3_2	421	426	PF14604	0.607
LIG_SH3_3	113	119	PF00018	0.644
LIG_SH3_3	418	424	PF00018	0.602
LIG_SH3_3	64	70	PF00018	0.682
LIG_SH3_3	72	78	PF00018	0.621
LIG_TRAF2_1	10	13	PF00917	0.638
LIG_TRAF2_1	34	37	PF00917	0.613
LIG_TRAF2_1	59	62	PF00917	0.609
LIG_WW_3	422	426	PF00397	0.563
MOD_CDK_SPK_2	150	155	PF00069	0.683
MOD_CDK_SPK_2	66	71	PF00069	0.653
MOD_CDK_SPxxK_3	358	365	PF00069	0.606
MOD_CDK_SPxxK_3	389	396	PF00069	0.679
MOD_CK1_1	144	150	PF00069	0.681
MOD_CK1_1	153	159	PF00069	0.573
MOD_CK1_1	169	175	PF00069	0.533
MOD_CK1_1	220	226	PF00069	0.582
MOD_CK1_1	360	366	PF00069	0.662
MOD_CK1_1	373	379	PF00069	0.572
MOD_CK1_1	392	398	PF00069	0.680
MOD_CK1_1	400	406	PF00069	0.553
MOD_CK1_1	428	434	PF00069	0.612
MOD_CK2_1	120	126	PF00069	0.724
MOD_CK2_1	169	175	PF00069	0.524
MOD_CK2_1	20	26	PF00069	0.658
MOD_CK2_1	224	230	PF00069	0.487
MOD_CK2_1	317	323	PF00069	0.549
MOD_CK2_1	56	62	PF00069	0.693
MOD_CK2_1	66	72	PF00069	0.666
MOD_DYRK1A_RPxSP_1	398	402	PF00069	0.629
MOD_GlcNHglycan	106	109	PF01048	0.635
MOD_GlcNHglycan	157	160	PF01048	0.679
MOD_GlcNHglycan	168	171	PF01048	0.559
MOD_GlcNHglycan	192	195	PF01048	0.548
MOD_GlcNHglycan	197	200	PF01048	0.577
MOD_GlcNHglycan	249	253	PF01048	0.460
MOD_GlcNHglycan	40	43	PF01048	0.674
MOD_GlcNHglycan	432	436	PF01048	0.755
MOD_GlcNHglycan	52	56	PF01048	0.615
MOD_GlcNHglycan	6	9	PF01048	0.747
MOD_GSK3_1	139	146	PF00069	0.654
MOD_GSK3_1	150	157	PF00069	0.695
MOD_GSK3_1	158	165	PF00069	0.600
MOD_GSK3_1	186	193	PF00069	0.551
MOD_GSK3_1	217	224	PF00069	0.539
MOD_GSK3_1	356	363	PF00069	0.667
MOD_GSK3_1	370	377	PF00069	0.656
MOD_GSK3_1	388	395	PF00069	0.691
MOD_GSK3_1	396	403	PF00069	0.601
MOD_GSK3_1	47	54	PF00069	0.740
MOD_GSK3_1	56	63	PF00069	0.660
MOD_N-GLC_1	381	386	PF02516	0.613
MOD_NEK2_1	288	293	PF00069	0.625
MOD_NEK2_1	317	322	PF00069	0.498
MOD_NEK2_1	60	65	PF00069	0.656
MOD_PIKK_1	125	131	PF00454	0.593
MOD_PK_1	186	192	PF00069	0.586
MOD_PK_1	201	207	PF00069	0.520
MOD_PK_1	221	227	PF00069	0.390
MOD_PK_1	341	347	PF00069	0.597
MOD_PKA_1	185	191	PF00069	0.586
MOD_PKA_1	200	206	PF00069	0.520
MOD_PKA_1	221	227	PF00069	0.482
MOD_PKA_1	341	347	PF00069	0.665
MOD_PKA_1	357	363	PF00069	0.523
MOD_PKA_1	38	44	PF00069	0.605
MOD_PKA_1	396	402	PF00069	0.646
MOD_PKA_1	425	431	PF00069	0.783
MOD_PKA_2	154	160	PF00069	0.716
MOD_PKA_2	185	191	PF00069	0.711
MOD_PKA_2	200	206	PF00069	0.520
MOD_PKA_2	220	226	PF00069	0.401
MOD_PKA_2	257	263	PF00069	0.418
MOD_PKA_2	297	303	PF00069	0.474
MOD_PKA_2	341	347	PF00069	0.649
MOD_PKA_2	356	362	PF00069	0.529
MOD_PKA_2	37	43	PF00069	0.677
MOD_PKA_2	387	393	PF00069	0.789
MOD_PKA_2	396	402	PF00069	0.563
MOD_PKA_2	4	10	PF00069	0.776
MOD_PKA_2	445	451	PF00069	0.587
MOD_PKB_1	139	147	PF00069	0.649
MOD_PKB_1	162	170	PF00069	0.634
MOD_PKB_1	183	191	PF00069	0.469
MOD_Plk_1	21	27	PF00069	0.651
MOD_Plk_1	258	264	PF00069	0.478
MOD_Plk_4	186	192	PF00069	0.521
MOD_Plk_4	221	227	PF00069	0.455
MOD_Plk_4	258	264	PF00069	0.428
MOD_Plk_4	317	323	PF00069	0.456
MOD_ProDKin_1	150	156	PF00069	0.687
MOD_ProDKin_1	358	364	PF00069	0.740
MOD_ProDKin_1	370	376	PF00069	0.716
MOD_ProDKin_1	389	395	PF00069	0.812
MOD_ProDKin_1	398	404	PF00069	0.615
MOD_ProDKin_1	438	444	PF00069	0.597
MOD_ProDKin_1	66	72	PF00069	0.713
TRG_ENDOCYTIC_2	318	321	PF00928	0.492
TRG_ENDOCYTIC_2	334	337	PF00928	0.480
TRG_ER_diArg_1	184	186	PF00400	0.562
TRG_ER_diArg_1	242	244	PF00400	0.631
TRG_ER_diArg_1	275	277	PF00400	0.535
TRG_ER_diArg_1	313	316	PF00400	0.518
TRG_ER_diArg_1	341	343	PF00400	0.530
TRG_ER_diArg_1	396	398	PF00400	0.697
TRG_Pf-PMV_PEXEL_1	315	319	PF00026	0.456

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HZG0	Leptomonas seymouri	39%	100%
A4H5T9	Leishmania braziliensis	64%	100%
A4HU33	Leishmania infantum	100%	100%
E9AMW2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%
Q4QHR4	Leishmania major	89%	100%