Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7WQR9_LEIDO

TriTrypDb:

LdBPK_091040.1 , LdCL_090015900 , LDHU3_09.1210

Length:

997

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WQR9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WQR9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	283	287	PF00656	0.514
CLV_C14_Caspase3-7	623	627	PF00656	0.594
CLV_NRD_NRD_1	194	196	PF00675	0.617
CLV_NRD_NRD_1	240	242	PF00675	0.587
CLV_NRD_NRD_1	424	426	PF00675	0.455
CLV_NRD_NRD_1	581	583	PF00675	0.652
CLV_NRD_NRD_1	6	8	PF00675	0.496
CLV_NRD_NRD_1	739	741	PF00675	0.675
CLV_NRD_NRD_1	888	890	PF00675	0.560
CLV_PCSK_FUR_1	238	242	PF00082	0.579
CLV_PCSK_KEX2_1	105	107	PF00082	0.650
CLV_PCSK_KEX2_1	196	198	PF00082	0.622
CLV_PCSK_KEX2_1	207	209	PF00082	0.625
CLV_PCSK_KEX2_1	240	242	PF00082	0.587
CLV_PCSK_KEX2_1	423	425	PF00082	0.451
CLV_PCSK_KEX2_1	581	583	PF00082	0.653
CLV_PCSK_KEX2_1	6	8	PF00082	0.496
CLV_PCSK_KEX2_1	739	741	PF00082	0.675
CLV_PCSK_PC1ET2_1	105	107	PF00082	0.650
CLV_PCSK_PC1ET2_1	196	198	PF00082	0.622
CLV_PCSK_PC1ET2_1	207	209	PF00082	0.625
CLV_PCSK_PC7_1	419	425	PF00082	0.516
CLV_PCSK_SKI1_1	294	298	PF00082	0.504
CLV_PCSK_SKI1_1	371	375	PF00082	0.525
CLV_PCSK_SKI1_1	440	444	PF00082	0.468
CLV_PCSK_SKI1_1	6	10	PF00082	0.489
CLV_PCSK_SKI1_1	680	684	PF00082	0.507
CLV_PCSK_SKI1_1	872	876	PF00082	0.623
CLV_PCSK_SKI1_1	890	894	PF00082	0.619
CLV_Separin_Metazoa	368	372	PF03568	0.512
CLV_Separin_Metazoa	80	84	PF03568	0.595
DEG_APCC_DBOX_1	679	687	PF00400	0.511
DEG_Nend_UBRbox_3	1	3	PF02207	0.506
DEG_SCF_FBW7_1	113	118	PF00400	0.654
DEG_SCF_FBW7_1	741	748	PF00400	0.629
DEG_SCF_FBW7_2	115	122	PF00400	0.695
DEG_SPOP_SBC_1	265	269	PF00917	0.645
DEG_SPOP_SBC_1	321	325	PF00917	0.630
DEG_SPOP_SBC_1	383	387	PF00917	0.567
DEG_SPOP_SBC_1	459	463	PF00917	0.593
DEG_SPOP_SBC_1	800	804	PF00917	0.708
DEG_SPOP_SBC_1	978	982	PF00917	0.574
DOC_CKS1_1	116	121	PF01111	0.697
DOC_CKS1_1	125	130	PF01111	0.554
DOC_CKS1_1	170	175	PF01111	0.656
DOC_CYCLIN_yCln2_LP_2	883	886	PF00134	0.551
DOC_CYCLIN_yCln2_LP_2	89	92	PF00134	0.626
DOC_MAPK_gen_1	822	830	PF00069	0.684
DOC_MAPK_gen_1	889	896	PF00069	0.582
DOC_PP2B_LxvP_1	488	491	PF13499	0.622
DOC_PP2B_LxvP_1	727	730	PF13499	0.629
DOC_PP2B_LxvP_1	883	886	PF13499	0.590
DOC_PP2B_LxvP_1	89	92	PF13499	0.626
DOC_PP2B_PxIxI_1	478	484	PF00149	0.594
DOC_PP4_FxxP_1	573	576	PF00568	0.613
DOC_PP4_FxxP_1	929	932	PF00568	0.614
DOC_PP4_MxPP_1	493	496	PF00568	0.564
DOC_PP4_MxPP_1	884	887	PF00568	0.541
DOC_PP4_MxPP_1	939	942	PF00568	0.553
DOC_USP7_MATH_1	135	139	PF00917	0.685
DOC_USP7_MATH_1	181	185	PF00917	0.610
DOC_USP7_MATH_1	200	204	PF00917	0.719
DOC_USP7_MATH_1	214	218	PF00917	0.725
DOC_USP7_MATH_1	246	250	PF00917	0.697
DOC_USP7_MATH_1	266	270	PF00917	0.510
DOC_USP7_MATH_1	322	326	PF00917	0.717
DOC_USP7_MATH_1	358	362	PF00917	0.414
DOC_USP7_MATH_1	383	387	PF00917	0.620
DOC_USP7_MATH_1	459	463	PF00917	0.580
DOC_USP7_MATH_1	518	522	PF00917	0.641
DOC_USP7_MATH_1	537	541	PF00917	0.523
DOC_USP7_MATH_1	60	64	PF00917	0.663
DOC_USP7_MATH_1	656	660	PF00917	0.628
DOC_USP7_MATH_1	706	710	PF00917	0.613
DOC_USP7_MATH_1	74	78	PF00917	0.514
DOC_USP7_MATH_1	749	753	PF00917	0.679
DOC_USP7_MATH_1	820	824	PF00917	0.591
DOC_USP7_MATH_1	876	880	PF00917	0.546
DOC_USP7_MATH_1	888	892	PF00917	0.594
DOC_USP7_MATH_1	900	904	PF00917	0.598
DOC_USP7_MATH_1	914	918	PF00917	0.544
DOC_USP7_MATH_1	950	954	PF00917	0.502
DOC_USP7_UBL2_3	133	137	PF12436	0.594
DOC_WW_Pin1_4	109	114	PF00397	0.809
DOC_WW_Pin1_4	115	120	PF00397	0.686
DOC_WW_Pin1_4	124	129	PF00397	0.513
DOC_WW_Pin1_4	151	156	PF00397	0.683
DOC_WW_Pin1_4	169	174	PF00397	0.538
DOC_WW_Pin1_4	218	223	PF00397	0.630
DOC_WW_Pin1_4	252	257	PF00397	0.648
DOC_WW_Pin1_4	333	338	PF00397	0.811
DOC_WW_Pin1_4	360	365	PF00397	0.550
DOC_WW_Pin1_4	43	48	PF00397	0.615
DOC_WW_Pin1_4	491	496	PF00397	0.578
DOC_WW_Pin1_4	568	573	PF00397	0.627
DOC_WW_Pin1_4	589	594	PF00397	0.761
DOC_WW_Pin1_4	603	608	PF00397	0.554
DOC_WW_Pin1_4	63	68	PF00397	0.524
DOC_WW_Pin1_4	718	723	PF00397	0.675
DOC_WW_Pin1_4	741	746	PF00397	0.598
DOC_WW_Pin1_4	794	799	PF00397	0.641
DOC_WW_Pin1_4	816	821	PF00397	0.604
DOC_WW_Pin1_4	858	863	PF00397	0.677
DOC_WW_Pin1_4	912	917	PF00397	0.628
DOC_WW_Pin1_4	918	923	PF00397	0.645
DOC_WW_Pin1_4	983	988	PF00397	0.566
LIG_14-3-3_CanoR_1	304	310	PF00244	0.600
LIG_14-3-3_CanoR_1	342	350	PF00244	0.454
LIG_14-3-3_CanoR_1	512	520	PF00244	0.635
LIG_14-3-3_CanoR_1	640	646	PF00244	0.580
LIG_14-3-3_CanoR_1	801	806	PF00244	0.700
LIG_14-3-3_CanoR_1	824	829	PF00244	0.684
LIG_14-3-3_CanoR_1	841	851	PF00244	0.528
LIG_14-3-3_CanoR_1	889	896	PF00244	0.561
LIG_AP2alpha_2	949	951	PF02296	0.547
LIG_deltaCOP1_diTrp_1	949	957	PF00928	0.528
LIG_FHA_1	172	178	PF00498	0.581
LIG_FHA_1	199	205	PF00498	0.636
LIG_FHA_1	324	330	PF00498	0.598
LIG_FHA_1	342	348	PF00498	0.468
LIG_FHA_1	642	648	PF00498	0.600
LIG_FHA_1	668	674	PF00498	0.589
LIG_FHA_1	722	728	PF00498	0.624
LIG_FHA_1	756	762	PF00498	0.645
LIG_FHA_1	825	831	PF00498	0.684
LIG_FHA_1	846	852	PF00498	0.605
LIG_FHA_1	931	937	PF00498	0.568
LIG_FHA_1	99	105	PF00498	0.628
LIG_FHA_2	142	148	PF00498	0.647
LIG_FHA_2	160	166	PF00498	0.597
LIG_FHA_2	230	236	PF00498	0.520
LIG_FHA_2	341	347	PF00498	0.688
LIG_FHA_2	455	461	PF00498	0.525
LIG_FHA_2	49	55	PF00498	0.568
LIG_FHA_2	575	581	PF00498	0.546
LIG_FHA_2	621	627	PF00498	0.623
LIG_IBAR_NPY_1	549	551	PF08397	0.519
LIG_LIR_Apic_2	474	479	PF02991	0.579
LIG_LIR_Apic_2	571	576	PF02991	0.609
LIG_LIR_Gen_1	348	358	PF02991	0.556
LIG_LIR_Gen_1	372	381	PF02991	0.562
LIG_LIR_Gen_1	76	82	PF02991	0.559
LIG_LIR_Gen_1	953	958	PF02991	0.505
LIG_LIR_Gen_1	965	974	PF02991	0.479
LIG_LIR_Nem_3	348	353	PF02991	0.555
LIG_LIR_Nem_3	372	377	PF02991	0.684
LIG_LIR_Nem_3	634	639	PF02991	0.487
LIG_LIR_Nem_3	76	81	PF02991	0.563
LIG_LIR_Nem_3	949	954	PF02991	0.540
LIG_LIR_Nem_3	965	971	PF02991	0.488
LIG_PAM2_1	826	838	PF00658	0.683
LIG_Pex14_1	569	573	PF04695	0.610
LIG_Pex14_2	608	612	PF04695	0.583
LIG_SH2_CRK	476	480	PF00017	0.599
LIG_SH2_CRK	545	549	PF00017	0.587
LIG_SH2_CRK	968	972	PF00017	0.478
LIG_SH2_GRB2like	968	971	PF00017	0.534
LIG_SH2_SRC	968	971	PF00017	0.534
LIG_SH2_STAP1	954	958	PF00017	0.502
LIG_SH2_STAT3	427	430	PF00017	0.437
LIG_SH2_STAT5	299	302	PF00017	0.469
LIG_SH2_STAT5	427	430	PF00017	0.437
LIG_SH3_2	337	342	PF14604	0.552
LIG_SH3_2	885	890	PF14604	0.659
LIG_SH3_3	101	107	PF00018	0.617
LIG_SH3_3	113	119	PF00018	0.635
LIG_SH3_3	326	332	PF00018	0.628
LIG_SH3_3	334	340	PF00018	0.584
LIG_SH3_3	466	472	PF00018	0.727
LIG_SH3_3	489	495	PF00018	0.600
LIG_SH3_3	559	565	PF00018	0.593
LIG_SH3_3	601	607	PF00018	0.658
LIG_SH3_3	610	616	PF00018	0.558
LIG_SH3_3	64	70	PF00018	0.642
LIG_SH3_3	708	714	PF00018	0.635
LIG_SH3_3	831	837	PF00018	0.592
LIG_SH3_3	870	876	PF00018	0.587
LIG_SH3_3	882	888	PF00018	0.602
LIG_SH3_3	893	899	PF00018	0.557
LIG_SH3_3	934	940	PF00018	0.675
LIG_SH3_3	990	996	PF00018	0.593
LIG_SUMO_SIM_anti_2	366	372	PF11976	0.443
LIG_SUMO_SIM_par_1	409	414	PF11976	0.524
LIG_SUMO_SIM_par_1	670	676	PF11976	0.573
LIG_TRAF2_1	120	123	PF00917	0.699
LIG_TRAF2_1	162	165	PF00917	0.786
LIG_TRAF2_1	233	236	PF00917	0.571
LIG_TRAF2_1	676	679	PF00917	0.549
LIG_TRAF2_1	806	809	PF00917	0.633
LIG_UBA3_1	432	440	PF00899	0.494
LIG_WW_2	941	944	PF00397	0.548
LIG_WW_3	736	740	PF00397	0.622
LIG_WW_3	886	890	PF00397	0.552
MOD_CDK_SPxK_1	816	822	PF00069	0.637
MOD_CDK_SPxK_1	858	864	PF00069	0.656
MOD_CDK_SPxxK_3	794	801	PF00069	0.644
MOD_CK1_1	179	185	PF00069	0.643
MOD_CK1_1	198	204	PF00069	0.536
MOD_CK1_1	213	219	PF00069	0.565
MOD_CK1_1	267	273	PF00069	0.593
MOD_CK1_1	323	329	PF00069	0.630
MOD_CK1_1	592	598	PF00069	0.599
MOD_CK1_1	63	69	PF00069	0.619
MOD_CK1_1	652	658	PF00069	0.765
MOD_CK1_1	770	776	PF00069	0.681
MOD_CK1_1	799	805	PF00069	0.654
MOD_CK1_1	823	829	PF00069	0.637
MOD_CK1_1	845	851	PF00069	0.639
MOD_CK1_1	860	866	PF00069	0.653
MOD_CK1_1	879	885	PF00069	0.502
MOD_CK1_1	917	923	PF00069	0.625
MOD_CK1_1	985	991	PF00069	0.716
MOD_CK2_1	141	147	PF00069	0.666
MOD_CK2_1	151	157	PF00069	0.616
MOD_CK2_1	159	165	PF00069	0.669
MOD_CK2_1	229	235	PF00069	0.591
MOD_CK2_1	321	327	PF00069	0.724
MOD_CK2_1	340	346	PF00069	0.568
MOD_CK2_1	454	460	PF00069	0.573
MOD_CK2_1	48	54	PF00069	0.609
MOD_CK2_1	518	524	PF00069	0.693
MOD_CK2_1	656	662	PF00069	0.760
MOD_CK2_1	673	679	PF00069	0.451
MOD_CK2_1	74	80	PF00069	0.593
MOD_GlcNHglycan	137	140	PF01048	0.679
MOD_GlcNHglycan	14	17	PF01048	0.518
MOD_GlcNHglycan	179	182	PF01048	0.681
MOD_GlcNHglycan	183	186	PF01048	0.760
MOD_GlcNHglycan	204	207	PF01048	0.650
MOD_GlcNHglycan	211	215	PF01048	0.703
MOD_GlcNHglycan	216	219	PF01048	0.810
MOD_GlcNHglycan	248	251	PF01048	0.652
MOD_GlcNHglycan	269	272	PF01048	0.756
MOD_GlcNHglycan	286	289	PF01048	0.431
MOD_GlcNHglycan	463	466	PF01048	0.647
MOD_GlcNHglycan	502	505	PF01048	0.698
MOD_GlcNHglycan	514	517	PF01048	0.656
MOD_GlcNHglycan	62	65	PF01048	0.662
MOD_GlcNHglycan	622	626	PF01048	0.606
MOD_GlcNHglycan	667	670	PF01048	0.642
MOD_GlcNHglycan	753	756	PF01048	0.657
MOD_GlcNHglycan	798	801	PF01048	0.643
MOD_GlcNHglycan	876	879	PF01048	0.584
MOD_GlcNHglycan	890	893	PF01048	0.581
MOD_GlcNHglycan	92	95	PF01048	0.679
MOD_GlcNHglycan	924	927	PF01048	0.634
MOD_GlcNHglycan	945	948	PF01048	0.548
MOD_GlcNHglycan	987	990	PF01048	0.683
MOD_GSK3_1	107	114	PF00069	0.687
MOD_GSK3_1	137	144	PF00069	0.615
MOD_GSK3_1	149	156	PF00069	0.622
MOD_GSK3_1	168	175	PF00069	0.545
MOD_GSK3_1	177	184	PF00069	0.588
MOD_GSK3_1	198	205	PF00069	0.717
MOD_GSK3_1	209	216	PF00069	0.587
MOD_GSK3_1	220	227	PF00069	0.626
MOD_GSK3_1	242	249	PF00069	0.632
MOD_GSK3_1	338	345	PF00069	0.611
MOD_GSK3_1	454	461	PF00069	0.607
MOD_GSK3_1	568	575	PF00069	0.631
MOD_GSK3_1	59	66	PF00069	0.662
MOD_GSK3_1	617	624	PF00069	0.615
MOD_GSK3_1	646	653	PF00069	0.609
MOD_GSK3_1	656	663	PF00069	0.571
MOD_GSK3_1	717	724	PF00069	0.619
MOD_GSK3_1	741	748	PF00069	0.625
MOD_GSK3_1	751	758	PF00069	0.589
MOD_GSK3_1	796	803	PF00069	0.703
MOD_GSK3_1	812	819	PF00069	0.526
MOD_GSK3_1	820	827	PF00069	0.563
MOD_GSK3_1	854	861	PF00069	0.591
MOD_GSK3_1	874	881	PF00069	0.585
MOD_GSK3_1	910	917	PF00069	0.615
MOD_GSK3_1	918	925	PF00069	0.634
MOD_GSK3_1	977	984	PF00069	0.665
MOD_N-GLC_1	177	182	PF02516	0.576
MOD_N-GLC_1	241	246	PF02516	0.606
MOD_N-GLC_1	284	289	PF02516	0.503
MOD_N-GLC_1	358	363	PF02516	0.503
MOD_N-GLC_1	665	670	PF02516	0.619
MOD_N-GLC_1	843	848	PF02516	0.622
MOD_NEK2_1	667	672	PF00069	0.630
MOD_NEK2_1	723	728	PF00069	0.611
MOD_NEK2_2	552	557	PF00069	0.557
MOD_PIKK_1	137	143	PF00454	0.576
MOD_PIKK_1	166	172	PF00454	0.699
MOD_PIKK_1	220	226	PF00454	0.588
MOD_PIKK_1	441	447	PF00454	0.496
MOD_PIKK_1	555	561	PF00454	0.580
MOD_PIKK_1	641	647	PF00454	0.585
MOD_PIKK_1	656	662	PF00454	0.524
MOD_PIKK_1	673	679	PF00454	0.488
MOD_PIKK_1	770	776	PF00454	0.666
MOD_PK_1	707	713	PF00069	0.573
MOD_PKA_1	195	201	PF00069	0.650
MOD_PKA_2	242	248	PF00069	0.618
MOD_PKA_2	303	309	PF00069	0.591
MOD_PKA_2	341	347	PF00069	0.485
MOD_PKA_2	800	806	PF00069	0.700
MOD_PKA_2	823	829	PF00069	0.683
MOD_PKA_2	888	894	PF00069	0.560
MOD_Plk_1	284	290	PF00069	0.500
MOD_Plk_1	358	364	PF00069	0.499
MOD_Plk_1	661	667	PF00069	0.759
MOD_Plk_1	678	684	PF00069	0.424
MOD_Plk_1	775	781	PF00069	0.620
MOD_Plk_4	552	558	PF00069	0.559
MOD_Plk_4	879	885	PF00069	0.606
MOD_Plk_4	99	105	PF00069	0.645
MOD_ProDKin_1	109	115	PF00069	0.807
MOD_ProDKin_1	124	130	PF00069	0.508
MOD_ProDKin_1	151	157	PF00069	0.684
MOD_ProDKin_1	169	175	PF00069	0.539
MOD_ProDKin_1	218	224	PF00069	0.629
MOD_ProDKin_1	252	258	PF00069	0.644
MOD_ProDKin_1	333	339	PF00069	0.809
MOD_ProDKin_1	360	366	PF00069	0.544
MOD_ProDKin_1	43	49	PF00069	0.619
MOD_ProDKin_1	491	497	PF00069	0.581
MOD_ProDKin_1	568	574	PF00069	0.628
MOD_ProDKin_1	589	595	PF00069	0.770
MOD_ProDKin_1	603	609	PF00069	0.555
MOD_ProDKin_1	63	69	PF00069	0.523
MOD_ProDKin_1	718	724	PF00069	0.676
MOD_ProDKin_1	741	747	PF00069	0.598
MOD_ProDKin_1	794	800	PF00069	0.641
MOD_ProDKin_1	816	822	PF00069	0.605
MOD_ProDKin_1	858	864	PF00069	0.677
MOD_ProDKin_1	912	918	PF00069	0.628
MOD_ProDKin_1	983	989	PF00069	0.566
MOD_SUMO_rev_2	19	27	PF00179	0.537
TRG_DiLeu_BaEn_4	678	684	PF01217	0.534
TRG_DiLeu_BaLyEn_6	291	296	PF01217	0.491
TRG_ENDOCYTIC_2	551	554	PF00928	0.583
TRG_ENDOCYTIC_2	954	957	PF00928	0.513
TRG_ENDOCYTIC_2	968	971	PF00928	0.475
TRG_ER_diArg_1	194	197	PF00400	0.619
TRG_ER_diArg_1	237	240	PF00400	0.584
TRG_ER_diArg_1	423	425	PF00400	0.454
TRG_ER_diArg_1	5	7	PF00400	0.504
TRG_ER_diArg_1	581	584	PF00400	0.656
TRG_ER_diArg_1	738	740	PF00400	0.668
TRG_NES_CRM1_1	346	360	PF08389	0.442
TRG_NLS_MonoCore_2	104	109	PF00514	0.633
TRG_NLS_MonoExtC_3	194	199	PF00514	0.621
TRG_NLS_MonoExtN_4	195	200	PF00514	0.621
TRG_Pf-PMV_PEXEL_1	371	375	PF00026	0.525
TRG_Pf-PMV_PEXEL_1	7	12	PF00026	0.492

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PAC9	Leptomonas seymouri	40%	96%
A4H5S6	Leishmania braziliensis	64%	100%
A4HU20	Leishmania infantum	99%	100%
E9AMV0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%
Q4QHS6	Leishmania major	89%	100%