LeishMANIAdb
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Kinesin, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Kinesin, putative
Gene product:
kinesin, putative
Species:
Leishmania donovani
UniProt:
A0A3S7WQI4_LEIDO
TriTrypDb:
LdBPK_090150.1 * , LdCL_090006400 , LDHU3_09.0200
Length:
1084

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
TermNameLevelCount
GO:0005871 kinesin complex 3 1
GO:0005874 microtubule 6 5
GO:0005875 microtubule associated complex 2 1
GO:0032991 protein-containing complex 1 1
GO:0099080 supramolecular complex 2 5
GO:0099081 supramolecular polymer 3 5
GO:0099512 supramolecular fiber 4 5
GO:0099513 polymeric cytoskeletal fiber 5 5
GO:0110165 cellular anatomical entity 1 5
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Expansion

Sequence features

A0A3S7WQI4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WQI4

Function

Biological processes
TermNameLevelCount
GO:0007017 microtubule-based process 2 11
GO:0007018 microtubule-based movement 3 11
GO:0009987 cellular process 1 11
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Molecular functions
TermNameLevelCount
GO:0000166 nucleotide binding 3 11
GO:0003774 cytoskeletal motor activity 1 11
GO:0003777 microtubule motor activity 2 11
GO:0003824 catalytic activity 1 5
GO:0005488 binding 1 11
GO:0005515 protein binding 2 11
GO:0005524 ATP binding 5 11
GO:0008017 microtubule binding 5 11
GO:0008092 cytoskeletal protein binding 3 11
GO:0015631 tubulin binding 4 11
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 413 417 PF00656 0.606
CLV_C14_Caspase3-7 623 627 PF00656 0.713
CLV_C14_Caspase3-7 863 867 PF00656 0.733
CLV_NRD_NRD_1 179 181 PF00675 0.445
CLV_NRD_NRD_1 192 194 PF00675 0.280
CLV_NRD_NRD_1 197 199 PF00675 0.217
CLV_NRD_NRD_1 247 249 PF00675 0.338
CLV_NRD_NRD_1 272 274 PF00675 0.447
CLV_NRD_NRD_1 345 347 PF00675 0.343
CLV_NRD_NRD_1 433 435 PF00675 0.576
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1HST2 Leptomonas seymouri 44% 98%
A0A1X0NPH9 Trypanosomatidae 35% 100%
A0A1X0NXX5 Trypanosomatidae 25% 100%
A0A422NE49 Trypanosoma rangeli 36% 100%
A4H5J0 Leishmania braziliensis 63% 100%
A4HTT1 Leishmania infantum 99% 100%
D0A992 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 36% 100%
E9AML4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 78% 100%
Q4QI22 Leishmania major 86% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS