LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7WQF4_LEIDO
TriTrypDb:
LdBPK_090010.1 , LdCL_090005000 , LDHU3_09.0020
Length:
144

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 1, no: 4
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WQF4
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WQF4

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 80 84 PF00656 0.632
CLV_C14_Caspase3-7 85 89 PF00656 0.577
CLV_NRD_NRD_1 116 118 PF00675 0.599
CLV_NRD_NRD_1 43 45 PF00675 0.487
CLV_PCSK_KEX2_1 106 108 PF00082 0.582
CLV_PCSK_KEX2_1 116 118 PF00082 0.530
CLV_PCSK_KEX2_1 30 32 PF00082 0.621
CLV_PCSK_KEX2_1 42 44 PF00082 0.486
CLV_PCSK_PC1ET2_1 106 108 PF00082 0.531
CLV_PCSK_PC1ET2_1 30 32 PF00082 0.621
CLV_PCSK_PC7_1 102 108 PF00082 0.533
CLV_PCSK_SKI1_1 119 123 PF00082 0.573
DEG_Nend_UBRbox_2 1 3 PF02207 0.633
DOC_CYCLIN_RxL_1 116 125 PF00134 0.572
DOC_MAPK_gen_1 106 114 PF00069 0.528
DOC_MAPK_gen_1 116 122 PF00069 0.450
DOC_USP7_MATH_1 87 91 PF00917 0.536
LIG_Actin_WH2_2 41 58 PF00022 0.590
LIG_FHA_2 78 84 PF00498 0.663
LIG_PCNA_yPIPBox_3 106 115 PF02747 0.414
LIG_PCNA_yPIPBox_3 95 105 PF02747 0.534
LIG_UBA3_1 111 119 PF00899 0.635
MOD_CK1_1 5 11 PF00069 0.737
MOD_CK1_1 89 95 PF00069 0.600
MOD_GlcNHglycan 10 13 PF01048 0.594
MOD_GlcNHglycan 123 127 PF01048 0.597
MOD_GlcNHglycan 4 8 PF01048 0.639
MOD_GlcNHglycan 91 94 PF01048 0.545
MOD_GSK3_1 2 9 PF00069 0.715
MOD_GSK3_1 62 69 PF00069 0.705
MOD_GSK3_1 73 80 PF00069 0.509
MOD_N-GLC_1 128 133 PF02516 0.643
MOD_NEK2_1 122 127 PF00069 0.604
MOD_PK_1 62 68 PF00069 0.514
MOD_PKA_1 62 68 PF00069 0.566
MOD_Plk_1 128 134 PF00069 0.621
MOD_Plk_4 62 68 PF00069 0.589
MOD_SUMO_for_1 94 97 PF00179 0.491
TRG_ER_diArg_1 115 117 PF00400 0.566
TRG_ER_diArg_1 41 44 PF00400 0.461
TRG_Pf-PMV_PEXEL_1 119 123 PF00026 0.659
TRG_Pf-PMV_PEXEL_1 22 26 PF00026 0.636

Homologs

Protein Taxonomy Sequence identity Coverage
A4H5H6 Leishmania braziliensis 58% 100%
A4HTR7 Leishmania infantum 98% 100%
E9AMK0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 73% 100%
Q4QI36 Leishmania major 79% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS