Protein kinase, putative

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

protein kinase, putative

Species:

Leishmania donovani

UniProt:

A0A3S7WQE5_LEIDO

TriTrypDb:

LdBPK_081250.1 , LdCL_080017500 , LDHU3_08.1650

Length:

854

Annotations

LeishMANIAdb annotations

A protein kinase likely belonging to the STE20 kinase family. The TM segments are a kinetoplastid innovation, but the kinase is otherwise conservative.

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	9
GO:0110165	cellular anatomical entity	1	9

Expansion

Sequence features

A0A3S7WQE5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WQE5

Function

Biological processes
Term	Name	Level	Count
GO:0006468	protein phosphorylation	5	10
GO:0006793	phosphorus metabolic process	3	10
GO:0006796	phosphate-containing compound metabolic process	4	10
GO:0006807	nitrogen compound metabolic process	2	10
GO:0008152	metabolic process	1	10
GO:0009987	cellular process	1	10
GO:0016310	phosphorylation	5	10
GO:0019538	protein metabolic process	3	10
GO:0036211	protein modification process	4	10
GO:0043170	macromolecule metabolic process	3	10
GO:0043412	macromolecule modification	4	10
GO:0044237	cellular metabolic process	2	10
GO:0044238	primary metabolic process	2	10
GO:0071704	organic substance metabolic process	2	10
GO:1901564	organonitrogen compound metabolic process	3	10
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006163	purine nucleotide metabolic process	5	1
GO:0006164	purine nucleotide biosynthetic process	6	1
GO:0006171	cAMP biosynthetic process	8	1
GO:0006182	cGMP biosynthetic process	8	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0006753	nucleoside phosphate metabolic process	4	1
GO:0009058	biosynthetic process	2	1
GO:0009117	nucleotide metabolic process	5	1
GO:0009150	purine ribonucleotide metabolic process	6	1
GO:0009152	purine ribonucleotide biosynthetic process	7	1
GO:0009165	nucleotide biosynthetic process	6	1
GO:0009187	cyclic nucleotide metabolic process	6	1
GO:0009190	cyclic nucleotide biosynthetic process	7	1
GO:0009259	ribonucleotide metabolic process	5	1
GO:0009260	ribonucleotide biosynthetic process	6	1
GO:0018130	heterocycle biosynthetic process	4	1
GO:0019438	aromatic compound biosynthetic process	4	1
GO:0019637	organophosphate metabolic process	3	1
GO:0019693	ribose phosphate metabolic process	4	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0034654	nucleobase-containing compound biosynthetic process	4	1
GO:0044249	cellular biosynthetic process	3	1
GO:0044271	cellular nitrogen compound biosynthetic process	4	1
GO:0044281	small molecule metabolic process	2	1
GO:0046058	cAMP metabolic process	7	1
GO:0046068	cGMP metabolic process	7	1
GO:0046390	ribose phosphate biosynthetic process	5	1
GO:0046483	heterocycle metabolic process	3	1
GO:0052652	cyclic purine nucleotide metabolic process	6	1
GO:0055086	nucleobase-containing small molecule metabolic process	3	1
GO:0072521	purine-containing compound metabolic process	4	1
GO:0072522	purine-containing compound biosynthetic process	5	1
GO:0090407	organophosphate biosynthetic process	4	1
GO:1901135	carbohydrate derivative metabolic process	3	1
GO:1901137	carbohydrate derivative biosynthetic process	4	1
GO:1901293	nucleoside phosphate biosynthetic process	5	1
GO:1901360	organic cyclic compound metabolic process	3	1
GO:1901362	organic cyclic compound biosynthetic process	4	1
GO:1901566	organonitrogen compound biosynthetic process	4	1
GO:1901576	organic substance biosynthetic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	10
GO:0003824	catalytic activity	1	10
GO:0004672	protein kinase activity	3	10
GO:0005488	binding	1	10
GO:0005524	ATP binding	5	10
GO:0016301	kinase activity	4	10
GO:0016740	transferase activity	2	10
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	10
GO:0016773	phosphotransferase activity, alcohol group as acceptor	4	10
GO:0017076	purine nucleotide binding	4	10
GO:0030554	adenyl nucleotide binding	5	10
GO:0032553	ribonucleotide binding	3	10
GO:0032555	purine ribonucleotide binding	4	10
GO:0032559	adenyl ribonucleotide binding	5	10
GO:0035639	purine ribonucleoside triphosphate binding	4	10
GO:0036094	small molecule binding	2	10
GO:0043167	ion binding	2	10
GO:0043168	anion binding	3	10
GO:0097159	organic cyclic compound binding	2	10
GO:0097367	carbohydrate derivative binding	2	10
GO:0140096	catalytic activity, acting on a protein	2	10
GO:1901265	nucleoside phosphate binding	3	10
GO:1901363	heterocyclic compound binding	2	10
GO:0004674	protein serine/threonine kinase activity	4	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	118	120	PF00675	0.520
CLV_NRD_NRD_1	277	279	PF00675	0.580
CLV_NRD_NRD_1	299	301	PF00675	0.517
CLV_NRD_NRD_1	384	386	PF00675	0.560
CLV_NRD_NRD_1	474	476	PF00675	0.616
CLV_NRD_NRD_1	615	617	PF00675	0.322
CLV_NRD_NRD_1	736	738	PF00675	0.356
CLV_NRD_NRD_1	830	832	PF00675	0.342
CLV_PCSK_FUR_1	613	617	PF00082	0.327
CLV_PCSK_KEX2_1	118	120	PF00082	0.520
CLV_PCSK_KEX2_1	277	279	PF00082	0.483
CLV_PCSK_KEX2_1	298	300	PF00082	0.485
CLV_PCSK_KEX2_1	384	386	PF00082	0.560
CLV_PCSK_KEX2_1	474	476	PF00082	0.628
CLV_PCSK_KEX2_1	613	615	PF00082	0.324
CLV_PCSK_KEX2_1	736	738	PF00082	0.356
CLV_PCSK_KEX2_1	805	807	PF00082	0.344
CLV_PCSK_KEX2_1	830	832	PF00082	0.342
CLV_PCSK_PC1ET2_1	298	300	PF00082	0.525
CLV_PCSK_PC1ET2_1	805	807	PF00082	0.334
CLV_PCSK_PC1ET2_1	830	832	PF00082	0.358
CLV_PCSK_SKI1_1	191	195	PF00082	0.568
CLV_PCSK_SKI1_1	352	356	PF00082	0.501
CLV_PCSK_SKI1_1	411	415	PF00082	0.493
CLV_PCSK_SKI1_1	600	604	PF00082	0.394
CLV_PCSK_SKI1_1	736	740	PF00082	0.358
CLV_PCSK_SKI1_1	802	806	PF00082	0.377
CLV_PCSK_SKI1_1	814	818	PF00082	0.269
CLV_PCSK_SKI1_1	832	836	PF00082	0.229
CLV_Separin_Metazoa	314	318	PF03568	0.753
DEG_Nend_UBRbox_1	1	4	PF02207	0.811
DEG_SCF_FBW7_1	522	528	PF00400	0.758
DEG_SCF_FBW7_1	556	562	PF00400	0.701
DEG_SPOP_SBC_1	39	43	PF00917	0.688
DEG_SPOP_SBC_1	446	450	PF00917	0.798
DEG_SPOP_SBC_1	847	851	PF00917	0.703
DOC_ANK_TNKS_1	694	701	PF00023	0.606
DOC_CDC14_PxL_1	423	431	PF14671	0.730
DOC_CDC14_PxL_1	45	53	PF14671	0.498
DOC_CKS1_1	12	17	PF01111	0.669
DOC_CKS1_1	440	445	PF01111	0.758
DOC_CKS1_1	522	527	PF01111	0.758
DOC_CKS1_1	556	561	PF01111	0.710
DOC_CKS1_1	808	813	PF01111	0.558
DOC_CYCLIN_yCln2_LP_2	547	553	PF00134	0.680
DOC_MAPK_gen_1	298	307	PF00069	0.673
DOC_MAPK_gen_1	340	348	PF00069	0.683
DOC_MAPK_gen_1	614	625	PF00069	0.522
DOC_MAPK_gen_1	813	821	PF00069	0.554
DOC_MAPK_HePTP_8	297	309	PF00069	0.711
DOC_MAPK_MEF2A_6	298	306	PF00069	0.676
DOC_MAPK_MEF2A_6	582	590	PF00069	0.534
DOC_MAPK_MEF2A_6	813	821	PF00069	0.594
DOC_MAPK_MEF2A_6	95	103	PF00069	0.361
DOC_PP1_RVXF_1	276	283	PF00149	0.677
DOC_PP2B_LxvP_1	46	49	PF13499	0.498
DOC_PP2B_LxvP_1	838	841	PF13499	0.558
DOC_PP4_FxxP_1	239	242	PF00568	0.817
DOC_USP7_MATH_1	196	200	PF00917	0.819
DOC_USP7_MATH_1	446	450	PF00917	0.798
DOC_USP7_MATH_1	540	544	PF00917	0.766
DOC_USP7_MATH_1	677	681	PF00917	0.565
DOC_USP7_MATH_1	741	745	PF00917	0.464
DOC_USP7_MATH_1	84	88	PF00917	0.540
DOC_USP7_MATH_1	847	851	PF00917	0.712
DOC_USP7_UBL2_3	835	839	PF12436	0.596
DOC_WW_Pin1_4	11	16	PF00397	0.764
DOC_WW_Pin1_4	202	207	PF00397	0.827
DOC_WW_Pin1_4	217	222	PF00397	0.659
DOC_WW_Pin1_4	245	250	PF00397	0.763
DOC_WW_Pin1_4	384	389	PF00397	0.722
DOC_WW_Pin1_4	439	444	PF00397	0.725
DOC_WW_Pin1_4	447	452	PF00397	0.747
DOC_WW_Pin1_4	521	526	PF00397	0.762
DOC_WW_Pin1_4	541	546	PF00397	0.631
DOC_WW_Pin1_4	555	560	PF00397	0.582
DOC_WW_Pin1_4	746	751	PF00397	0.521
DOC_WW_Pin1_4	807	812	PF00397	0.558
LIG_14-3-3_CanoR_1	277	283	PF00244	0.828
LIG_14-3-3_CanoR_1	352	358	PF00244	0.660
LIG_14-3-3_CanoR_1	36	46	PF00244	0.710
LIG_14-3-3_CanoR_1	474	482	PF00244	0.790
LIG_14-3-3_CanoR_1	587	597	PF00244	0.549
LIG_14-3-3_CanoR_1	642	652	PF00244	0.606
LIG_14-3-3_CanoR_1	736	746	PF00244	0.558
LIG_14-3-3_CanoR_1	74	79	PF00244	0.531
LIG_14-3-3_CanoR_1	831	838	PF00244	0.558
LIG_14-3-3_CanoR_1	95	99	PF00244	0.406
LIG_Actin_WH2_2	648	664	PF00022	0.618
LIG_AP2alpha_1	378	382	PF02296	0.746
LIG_APCC_ABBA_1	346	351	PF00400	0.674
LIG_APCC_ABBAyCdc20_2	707	713	PF00400	0.596
LIG_BRCT_BRCA1_1	146	150	PF00533	0.753
LIG_BRCT_BRCA1_1	278	282	PF00533	0.770
LIG_BRCT_BRCA1_1	326	330	PF00533	0.689
LIG_BRCT_BRCA1_1	542	546	PF00533	0.757
LIG_CSL_BTD_1	246	249	PF09270	0.808
LIG_deltaCOP1_diTrp_1	767	771	PF00928	0.519
LIG_EH1_1	55	63	PF00400	0.499
LIG_FHA_1	187	193	PF00498	0.780
LIG_FHA_1	281	287	PF00498	0.722
LIG_FHA_1	39	45	PF00498	0.658
LIG_FHA_1	398	404	PF00498	0.704
LIG_FHA_1	518	524	PF00498	0.799
LIG_FHA_1	52	58	PF00498	0.301
LIG_FHA_1	644	650	PF00498	0.543
LIG_FHA_1	66	72	PF00498	0.402
LIG_FHA_1	737	743	PF00498	0.567
LIG_FHA_1	778	784	PF00498	0.596
LIG_FHA_2	12	18	PF00498	0.682
LIG_FHA_2	26	32	PF00498	0.729
LIG_FHA_2	309	315	PF00498	0.750
LIG_FHA_2	405	411	PF00498	0.707
LIG_FHA_2	426	432	PF00498	0.764
LIG_FHA_2	474	480	PF00498	0.812
LIG_FHA_2	492	498	PF00498	0.735
LIG_FHA_2	5	11	PF00498	0.744
LIG_FHA_2	505	511	PF00498	0.766
LIG_FHA_2	556	562	PF00498	0.706
LIG_FHA_2	624	630	PF00498	0.559
LIG_FHA_2	756	762	PF00498	0.623
LIG_FHA_2	822	828	PF00498	0.562
LIG_FHA_2	831	837	PF00498	0.494
LIG_GBD_Chelix_1	302	310	PF00786	0.552
LIG_Integrin_RGD_1	606	608	PF01839	0.406
LIG_IRF3_LxIS_1	106	113	PF10401	0.440
LIG_IRF3_LxIS_1	585	591	PF10401	0.606
LIG_LIR_Apic_2	749	755	PF02991	0.519
LIG_LIR_Gen_1	113	121	PF02991	0.524
LIG_LIR_Gen_1	356	364	PF02991	0.699
LIG_LIR_Gen_1	42	51	PF02991	0.571
LIG_LIR_Gen_1	453	462	PF02991	0.771
LIG_LIR_Gen_1	558	564	PF02991	0.669
LIG_LIR_Gen_1	593	604	PF02991	0.579
LIG_LIR_Gen_1	70	79	PF02991	0.489
LIG_LIR_Gen_1	97	108	PF02991	0.398
LIG_LIR_Nem_3	113	117	PF02991	0.352
LIG_LIR_Nem_3	147	152	PF02991	0.727
LIG_LIR_Nem_3	171	175	PF02991	0.680
LIG_LIR_Nem_3	308	312	PF02991	0.699
LIG_LIR_Nem_3	356	360	PF02991	0.644
LIG_LIR_Nem_3	42	48	PF02991	0.571
LIG_LIR_Nem_3	431	437	PF02991	0.717
LIG_LIR_Nem_3	453	457	PF02991	0.777
LIG_LIR_Nem_3	558	563	PF02991	0.693
LIG_LIR_Nem_3	593	599	PF02991	0.582
LIG_LIR_Nem_3	70	75	PF02991	0.494
LIG_LIR_Nem_3	791	795	PF02991	0.566
LIG_LIR_Nem_3	97	103	PF02991	0.398
LIG_MLH1_MIPbox_1	146	150	PF16413	0.724
LIG_PCNA_TLS_4	814	821	PF02747	0.596
LIG_PDZ_Class_3	849	854	PF00595	0.780
LIG_Pex14_1	168	172	PF04695	0.700
LIG_Pex14_1	357	361	PF04695	0.736
LIG_Pex14_2	378	382	PF04695	0.722
LIG_Rb_LxCxE_1	818	836	PF01857	0.461
LIG_SH2_CRK	96	100	PF00017	0.498
LIG_SH2_GRB2like	63	66	PF00017	0.570
LIG_SH2_PTP2	437	440	PF00017	0.722
LIG_SH2_PTP2	63	66	PF00017	0.570
LIG_SH2_SRC	24	27	PF00017	0.759
LIG_SH2_SRC	63	66	PF00017	0.570
LIG_SH2_SRC	826	829	PF00017	0.547
LIG_SH2_STAP1	349	353	PF00017	0.703
LIG_SH2_STAP1	560	564	PF00017	0.693
LIG_SH2_STAP1	785	789	PF00017	0.608
LIG_SH2_STAP1	96	100	PF00017	0.480
LIG_SH2_STAT5	393	396	PF00017	0.745
LIG_SH2_STAT5	399	402	PF00017	0.728
LIG_SH2_STAT5	434	437	PF00017	0.718
LIG_SH2_STAT5	63	66	PF00017	0.551
LIG_SH2_STAT5	651	654	PF00017	0.522
LIG_SH2_STAT5	667	670	PF00017	0.522
LIG_SH2_STAT5	793	796	PF00017	0.538
LIG_SH2_STAT5	842	845	PF00017	0.586
LIG_SH2_STAT5	96	99	PF00017	0.412
LIG_SH3_3	519	525	PF00018	0.792
LIG_SH3_3	539	545	PF00018	0.792
LIG_SH3_3	553	559	PF00018	0.677
LIG_SH3_3	716	722	PF00018	0.558
LIG_SH3_3	73	79	PF00018	0.489
LIG_SUMO_SIM_anti_2	102	107	PF11976	0.492
LIG_SUMO_SIM_anti_2	636	641	PF11976	0.561
LIG_SUMO_SIM_par_1	130	135	PF11976	0.728
LIG_SUMO_SIM_par_1	303	308	PF11976	0.710
LIG_SUMO_SIM_par_1	344	351	PF11976	0.718
LIG_TYR_ITIM	310	315	PF00017	0.634
LIG_TYR_ITIM	61	66	PF00017	0.569
LIG_WRC_WIRS_1	306	311	PF05994	0.703
LIG_WRC_WIRS_1	560	565	PF05994	0.548
LIG_WRC_WIRS_1	651	656	PF05994	0.434
LIG_WRC_WIRS_1	66	71	PF05994	0.541
LIG_WRC_WIRS_1	768	773	PF05994	0.376
MOD_CDK_SPxK_1	807	813	PF00069	0.425
MOD_CDK_SPxxK_3	807	814	PF00069	0.484
MOD_CK1_1	216	222	PF00069	0.768
MOD_CK1_1	253	259	PF00069	0.752
MOD_CK1_1	276	282	PF00069	0.652
MOD_CK1_1	308	314	PF00069	0.633
MOD_CK1_1	37	43	PF00069	0.607
MOD_CK1_1	387	393	PF00069	0.714
MOD_CK1_1	450	456	PF00069	0.783
MOD_CK1_1	70	76	PF00069	0.494
MOD_CK2_1	127	133	PF00069	0.665
MOD_CK2_1	19	25	PF00069	0.754
MOD_CK2_1	308	314	PF00069	0.668
MOD_CK2_1	4	10	PF00069	0.694
MOD_CK2_1	404	410	PF00069	0.558
MOD_CK2_1	425	431	PF00069	0.619
MOD_CK2_1	473	479	PF00069	0.789
MOD_CK2_1	555	561	PF00069	0.650
MOD_CK2_1	623	629	PF00069	0.440
MOD_CK2_1	650	656	PF00069	0.386
MOD_CK2_1	741	747	PF00069	0.466
MOD_CK2_1	755	761	PF00069	0.346
MOD_CK2_1	846	852	PF00069	0.638
MOD_Cter_Amidation	828	831	PF01082	0.294
MOD_GlcNHglycan	171	175	PF01048	0.677
MOD_GlcNHglycan	198	201	PF01048	0.757
MOD_GlcNHglycan	215	218	PF01048	0.485
MOD_GlcNHglycan	257	260	PF01048	0.813
MOD_GlcNHglycan	273	276	PF01048	0.758
MOD_GlcNHglycan	362	365	PF01048	0.600
MOD_GlcNHglycan	389	392	PF01048	0.606
MOD_GlcNHglycan	476	479	PF01048	0.807
MOD_GlcNHglycan	530	533	PF01048	0.748
MOD_GlcNHglycan	723	726	PF01048	0.431
MOD_GlcNHglycan	743	746	PF01048	0.385
MOD_GSK3_1	140	147	PF00069	0.637
MOD_GSK3_1	202	209	PF00069	0.821
MOD_GSK3_1	211	218	PF00069	0.701
MOD_GSK3_1	25	32	PF00069	0.655
MOD_GSK3_1	276	283	PF00069	0.725
MOD_GSK3_1	34	41	PF00069	0.565
MOD_GSK3_1	393	400	PF00069	0.649
MOD_GSK3_1	405	412	PF00069	0.525
MOD_GSK3_1	446	453	PF00069	0.712
MOD_GSK3_1	517	524	PF00069	0.727
MOD_GSK3_1	528	535	PF00069	0.749
MOD_GSK3_1	536	543	PF00069	0.721
MOD_GSK3_1	555	562	PF00069	0.590
MOD_GSK3_1	70	77	PF00069	0.509
MOD_GSK3_1	732	739	PF00069	0.387
MOD_GSK3_1	751	758	PF00069	0.427
MOD_N-GLC_2	335	337	PF02516	0.657
MOD_NEK2_1	110	115	PF00069	0.325
MOD_NEK2_1	293	298	PF00069	0.674
MOD_NEK2_1	305	310	PF00069	0.638
MOD_NEK2_1	360	365	PF00069	0.681
MOD_NEK2_1	452	457	PF00069	0.783
MOD_NEK2_1	473	478	PF00069	0.759
MOD_NEK2_1	51	56	PF00069	0.434
MOD_NEK2_1	573	578	PF00069	0.537
MOD_NEK2_1	676	681	PF00069	0.503
MOD_NEK2_1	732	737	PF00069	0.403
MOD_NEK2_1	99	104	PF00069	0.391
MOD_NEK2_2	559	564	PF00069	0.569
MOD_NEK2_2	785	790	PF00069	0.454
MOD_PIKK_1	206	212	PF00454	0.752
MOD_PIKK_1	793	799	PF00454	0.431
MOD_PKA_1	474	480	PF00069	0.757
MOD_PKA_1	736	742	PF00069	0.431
MOD_PKA_1	830	836	PF00069	0.431
MOD_PKA_2	161	167	PF00069	0.649
MOD_PKA_2	196	202	PF00069	0.713
MOD_PKA_2	276	282	PF00069	0.730
MOD_PKA_2	35	41	PF00069	0.724
MOD_PKA_2	473	479	PF00069	0.760
MOD_PKA_2	643	649	PF00069	0.498
MOD_PKA_2	736	742	PF00069	0.431
MOD_PKA_2	830	836	PF00069	0.376
MOD_PKA_2	94	100	PF00069	0.486
MOD_Plk_1	132	138	PF00069	0.625
MOD_Plk_1	293	299	PF00069	0.710
MOD_Plk_1	409	415	PF00069	0.605
MOD_Plk_1	464	470	PF00069	0.751
MOD_Plk_1	785	791	PF00069	0.454
MOD_Plk_1	84	90	PF00069	0.574
MOD_Plk_2-3	19	25	PF00069	0.777
MOD_Plk_4	127	133	PF00069	0.676
MOD_Plk_4	145	151	PF00069	0.717
MOD_Plk_4	19	25	PF00069	0.716
MOD_Plk_4	305	311	PF00069	0.597
MOD_Plk_4	40	46	PF00069	0.384
MOD_Plk_4	409	415	PF00069	0.605
MOD_Plk_4	418	424	PF00069	0.596
MOD_Plk_4	425	431	PF00069	0.550
MOD_Plk_4	51	57	PF00069	0.332
MOD_Plk_4	559	565	PF00069	0.548
MOD_Plk_4	573	579	PF00069	0.434
MOD_Plk_4	94	100	PF00069	0.427
MOD_ProDKin_1	11	17	PF00069	0.718
MOD_ProDKin_1	202	208	PF00069	0.806
MOD_ProDKin_1	217	223	PF00069	0.574
MOD_ProDKin_1	245	251	PF00069	0.718
MOD_ProDKin_1	384	390	PF00069	0.657
MOD_ProDKin_1	439	445	PF00069	0.667
MOD_ProDKin_1	447	453	PF00069	0.696
MOD_ProDKin_1	521	527	PF00069	0.715
MOD_ProDKin_1	541	547	PF00069	0.533
MOD_ProDKin_1	555	561	PF00069	0.449
MOD_ProDKin_1	746	752	PF00069	0.379
MOD_ProDKin_1	807	813	PF00069	0.431
MOD_SUMO_for_1	602	605	PF00179	0.440
MOD_SUMO_for_1	804	807	PF00179	0.396
MOD_SUMO_rev_2	574	583	PF00179	0.434
MOD_SUMO_rev_2	605	612	PF00179	0.498
MOD_SUMO_rev_2	653	661	PF00179	0.440
TRG_DiLeu_BaEn_1	410	415	PF01217	0.671
TRG_DiLeu_BaEn_2	591	597	PF01217	0.498
TRG_DiLeu_BaEn_2	698	704	PF01217	0.431
TRG_ENDOCYTIC_2	121	124	PF00928	0.578
TRG_ENDOCYTIC_2	312	315	PF00928	0.631
TRG_ENDOCYTIC_2	437	440	PF00928	0.659
TRG_ENDOCYTIC_2	560	563	PF00928	0.617
TRG_ENDOCYTIC_2	63	66	PF00928	0.564
TRG_ENDOCYTIC_2	651	654	PF00928	0.434
TRG_ENDOCYTIC_2	792	795	PF00928	0.484
TRG_ENDOCYTIC_2	96	99	PF00928	0.412
TRG_ER_diArg_1	117	119	PF00400	0.654
TRG_ER_diArg_1	383	385	PF00400	0.713
TRG_ER_diArg_1	473	475	PF00400	0.792
TRG_ER_diArg_1	612	615	PF00400	0.384
TRG_NES_CRM1_1	128	139	PF08389	0.665
TRG_NLS_Bipartite_1	813	834	PF00514	0.425
TRG_NLS_MonoExtN_4	828	834	PF00514	0.425

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P5H9	Leptomonas seymouri	48%	98%
A0A3S5H699	Leishmania donovani	100%	100%
A4HC47	Leishmania braziliensis	85%	99%
E9AG93	Leishmania infantum	100%	100%
E9AMJ7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	99%
Q4QI37	Leishmania major	95%	100%
Q4QI43	Leishmania major	96%	100%
V5BPV2	Trypanosoma cruzi	26%	88%