Transmembrane amino acid transporter family protein

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

amino acid transporter 19, putative

Species:

Leishmania donovani

UniProt:

A0A3S7WQ39_LEIDO

TriTrypDb:

LdBPK_071340.1 , LdCL_070018400 , LDHU3_07.1590

Length:

491

Annotations

LeishMANIAdb annotations

An enormously expanded group of various amino acid transporters.. Localization: Cell surface (by feature)

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 8
Forrest at al. (procyclic)	no	yes: 8
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 69

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 5

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 1, no: 173
NetGPI	no	yes: 0, no: 174

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	158
GO:0110165	cellular anatomical entity	1	158
GO:0005634	nucleus	5	1
GO:0005737	cytoplasm	2	1
GO:0005886	plasma membrane	3	1
GO:0020016	ciliary pocket	2	1
GO:0020023	kinetoplast	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1

Expansion

Sequence features

A0A3S7WQ39

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WQ39

Function

Biological processes
Term	Name	Level	Count
GO:0003333	amino acid transmembrane transport	5	17
GO:0006810	transport	3	17
GO:0006811	monoatomic ion transport	4	1
GO:0006812	monoatomic cation transport	5	1
GO:0006820	monoatomic anion transport	5	1
GO:0006865	amino acid transport	5	17
GO:0009987	cellular process	1	17
GO:0015711	organic anion transport	5	1
GO:0015802	basic amino acid transport	6	1
GO:0015819	lysine transport	6	1
GO:0015849	organic acid transport	5	17
GO:0046942	carboxylic acid transport	6	1
GO:0051179	localization	1	17
GO:0051234	establishment of localization	2	17
GO:0055085	transmembrane transport	2	17
GO:0071702	organic substance transport	4	17
GO:0071705	nitrogen compound transport	4	17
GO:1903825	organic acid transmembrane transport	3	17
GO:1905039	carboxylic acid transmembrane transport	4	17

Molecular functions
Term	Name	Level	Count
GO:0005215	transporter activity	1	17
GO:0005342	organic acid transmembrane transporter activity	3	17
GO:0008324	monoatomic cation transmembrane transporter activity	4	1
GO:0008509	monoatomic anion transmembrane transporter activity	4	1
GO:0008514	organic anion transmembrane transporter activity	5	1
GO:0015075	monoatomic ion transmembrane transporter activity	3	1
GO:0015171	amino acid transmembrane transporter activity	5	17
GO:0015174	basic amino acid transmembrane transporter activity	6	1
GO:0015179	L-amino acid transmembrane transporter activity	6	17
GO:0015189	L-lysine transmembrane transporter activity	5	1
GO:0022857	transmembrane transporter activity	2	17
GO:0046943	carboxylic acid transmembrane transporter activity	4	17

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	271	273	PF00675	0.516
CLV_PCSK_SKI1_1	15	19	PF00082	0.526
CLV_PCSK_SKI1_1	163	167	PF00082	0.271
CLV_PCSK_SKI1_1	273	277	PF00082	0.559
CLV_PCSK_SKI1_1	403	407	PF00082	0.205
CLV_Separin_Metazoa	208	212	PF03568	0.136
DEG_COP1_1	202	209	PF00400	0.278
DOC_CKS1_1	196	201	PF01111	0.269
DOC_CYCLIN_yCln2_LP_2	114	120	PF00134	0.333
DOC_MAPK_FxFP_2	442	445	PF00069	0.341
DOC_MAPK_MEF2A_6	241	250	PF00069	0.461
DOC_PP1_RVXF_1	271	278	PF00149	0.325
DOC_PP1_RVXF_1	83	89	PF00149	0.613
DOC_PP2B_LxvP_1	114	117	PF13499	0.330
DOC_PP2B_LxvP_1	17	20	PF13499	0.738
DOC_PP2B_LxvP_1	231	234	PF13499	0.279
DOC_PP2B_LxvP_1	420	423	PF13499	0.294
DOC_PP4_FxxP_1	201	204	PF00568	0.300
DOC_PP4_FxxP_1	442	445	PF00568	0.306
DOC_USP7_MATH_1	119	123	PF00917	0.293
DOC_USP7_MATH_1	147	151	PF00917	0.504
DOC_USP7_UBL2_3	454	458	PF12436	0.342
DOC_USP7_UBL2_3	79	83	PF12436	0.625
DOC_WW_Pin1_4	195	200	PF00397	0.287
DOC_WW_Pin1_4	309	314	PF00397	0.470
LIG_14-3-3_CanoR_1	148	155	PF00244	0.542
LIG_14-3-3_CanoR_1	241	248	PF00244	0.451
LIG_14-3-3_CanoR_1	318	324	PF00244	0.464
LIG_14-3-3_CanoR_1	341	347	PF00244	0.262
LIG_Actin_WH2_2	226	243	PF00022	0.274
LIG_Actin_WH2_2	372	387	PF00022	0.318
LIG_Actin_WH2_2	443	460	PF00022	0.327
LIG_BIR_II_1	1	5	PF00653	0.770
LIG_BRCT_BRCA1_1	121	125	PF00533	0.298
LIG_BRCT_BRCA1_1	261	265	PF00533	0.334
LIG_EH1_1	252	260	PF00400	0.256
LIG_FHA_1	125	131	PF00498	0.299
LIG_FHA_1	218	224	PF00498	0.321
LIG_FHA_1	241	247	PF00498	0.442
LIG_FHA_1	466	472	PF00498	0.298
LIG_FHA_2	155	161	PF00498	0.464
LIG_FHA_2	16	22	PF00498	0.704
LIG_GBD_Chelix_1	130	138	PF00786	0.301
LIG_GBD_Chelix_1	427	435	PF00786	0.425
LIG_LIR_Apic_2	198	204	PF02991	0.290
LIG_LIR_Apic_2	395	400	PF02991	0.495
LIG_LIR_Gen_1	157	166	PF02991	0.425
LIG_LIR_Gen_1	221	231	PF02991	0.283
LIG_LIR_Gen_1	290	301	PF02991	0.401
LIG_LIR_Gen_1	386	397	PF02991	0.449
LIG_LIR_Gen_1	466	477	PF02991	0.297
LIG_LIR_Gen_1	486	491	PF02991	0.353
LIG_LIR_Nem_3	157	161	PF02991	0.464
LIG_LIR_Nem_3	221	227	PF02991	0.276
LIG_LIR_Nem_3	290	296	PF02991	0.389
LIG_LIR_Nem_3	386	392	PF02991	0.462
LIG_LIR_Nem_3	393	397	PF02991	0.462
LIG_LIR_Nem_3	466	472	PF02991	0.300
LIG_LIR_Nem_3	486	491	PF02991	0.363
LIG_PDZ_Class_1	486	491	PF00595	0.491
LIG_Pex14_1	363	367	PF04695	0.402
LIG_Pex14_1	465	469	PF04695	0.496
LIG_Pex14_2	177	181	PF04695	0.355
LIG_Pex14_2	84	88	PF04695	0.625
LIG_SH2_NCK_1	158	162	PF00017	0.417
LIG_SH2_NCK_1	306	310	PF00017	0.523
LIG_SH2_PTP2	469	472	PF00017	0.209
LIG_SH2_SRC	158	161	PF00017	0.444
LIG_SH2_SRC	189	192	PF00017	0.287
LIG_SH2_STAP1	158	162	PF00017	0.457
LIG_SH2_STAP1	172	176	PF00017	0.330
LIG_SH2_STAT5	189	192	PF00017	0.283
LIG_SH2_STAT5	331	334	PF00017	0.306
LIG_SH2_STAT5	366	369	PF00017	0.338
LIG_SH2_STAT5	469	472	PF00017	0.293
LIG_SH3_3	2	8	PF00018	0.773
LIG_SH3_3	201	207	PF00018	0.256
LIG_SH3_3	224	230	PF00018	0.403
LIG_SH3_3	88	94	PF00018	0.590
LIG_SUMO_SIM_anti_2	127	133	PF11976	0.294
LIG_SUMO_SIM_anti_2	446	451	PF11976	0.318
LIG_SUMO_SIM_anti_2	468	474	PF11976	0.296
LIG_SUMO_SIM_par_1	130	136	PF11976	0.306
LIG_SUMO_SIM_par_1	188	195	PF11976	0.270
LIG_SUMO_SIM_par_1	243	249	PF11976	0.277
LIG_TYR_ITIM	467	472	PF00017	0.218
LIG_UBA3_1	228	235	PF00899	0.306
LIG_UBA3_1	447	454	PF00899	0.352
MOD_CDK_SPK_2	309	314	PF00069	0.452
MOD_CK1_1	100	106	PF00069	0.341
MOD_CK1_1	150	156	PF00069	0.481
MOD_CK1_1	217	223	PF00069	0.372
MOD_CK1_1	244	250	PF00069	0.380
MOD_CK1_1	35	41	PF00069	0.736
MOD_CK2_1	202	208	PF00069	0.237
MOD_GlcNHglycan	220	223	PF01048	0.266
MOD_GlcNHglycan	324	327	PF01048	0.327
MOD_GlcNHglycan	37	40	PF01048	0.486
MOD_GSK3_1	100	107	PF00069	0.324
MOD_GSK3_1	150	157	PF00069	0.448
MOD_GSK3_1	185	192	PF00069	0.345
MOD_GSK3_1	214	221	PF00069	0.152
MOD_GSK3_1	236	243	PF00069	0.445
MOD_GSK3_1	28	35	PF00069	0.761
MOD_GSK3_1	318	325	PF00069	0.473
MOD_GSK3_1	341	348	PF00069	0.249
MOD_N-GLC_1	318	323	PF02516	0.257
MOD_NEK2_1	104	109	PF00069	0.308
MOD_NEK2_1	209	214	PF00069	0.248
MOD_NEK2_1	240	245	PF00069	0.442
MOD_NEK2_1	277	282	PF00069	0.249
MOD_NEK2_1	342	347	PF00069	0.313
MOD_NEK2_1	384	389	PF00069	0.416
MOD_NEK2_1	431	436	PF00069	0.289
MOD_NEK2_1	463	468	PF00069	0.420
MOD_NEK2_2	453	458	PF00069	0.445
MOD_OFUCOSY	257	263	PF10250	0.352
MOD_PIKK_1	32	38	PF00454	0.711
MOD_PK_1	241	247	PF00069	0.491
MOD_PKA_2	147	153	PF00069	0.489
MOD_PKA_2	240	246	PF00069	0.502
MOD_PKA_2	317	323	PF00069	0.443
MOD_PKA_2	384	390	PF00069	0.478
MOD_Plk_1	318	324	PF00069	0.444
MOD_Plk_1	463	469	PF00069	0.467
MOD_Plk_2-3	202	208	PF00069	0.302
MOD_Plk_4	133	139	PF00069	0.289
MOD_Plk_4	185	191	PF00069	0.344
MOD_Plk_4	214	220	PF00069	0.309
MOD_Plk_4	241	247	PF00069	0.439
MOD_Plk_4	287	293	PF00069	0.342
MOD_Plk_4	346	352	PF00069	0.226
MOD_Plk_4	384	390	PF00069	0.457
MOD_Plk_4	443	449	PF00069	0.377
MOD_Plk_4	465	471	PF00069	0.456
MOD_Plk_4	483	489	PF00069	0.235
MOD_ProDKin_1	195	201	PF00069	0.287
MOD_ProDKin_1	309	315	PF00069	0.470
TRG_ENDOCYTIC_2	158	161	PF00928	0.387
TRG_ENDOCYTIC_2	305	308	PF00928	0.416
TRG_ENDOCYTIC_2	366	369	PF00928	0.316
TRG_ENDOCYTIC_2	389	392	PF00928	0.450
TRG_ENDOCYTIC_2	469	472	PF00928	0.287
TRG_ENDOCYTIC_2	488	491	PF00928	0.347
TRG_ENDOCYTIC_2	81	84	PF00928	0.609

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P285	Leptomonas seymouri	34%	100%
A0A0N0P5D2	Leptomonas seymouri	42%	100%
A0A0N0P613	Leptomonas seymouri	26%	100%
A0A0N0P6F5	Leptomonas seymouri	26%	100%
A0A0N0P6F6	Leptomonas seymouri	41%	100%
A0A0N0P8T9	Leptomonas seymouri	39%	98%
A0A0N0P955	Leptomonas seymouri	38%	100%
A0A0N1I2L5	Leptomonas seymouri	38%	100%
A0A0N1I3F8	Leptomonas seymouri	38%	92%
A0A0N1I3H4	Leptomonas seymouri	38%	89%
A0A0N1I8K7	Leptomonas seymouri	39%	100%
A0A0N1I8W4	Leptomonas seymouri	32%	100%
A0A0N1I9T3	Leptomonas seymouri	39%	100%
A0A0N1IAJ0	Leptomonas seymouri	24%	100%
A0A0N1IMP2	Leptomonas seymouri	45%	97%
A0A0N1PA98	Leptomonas seymouri	33%	80%
A0A0N1PBP2	Leptomonas seymouri	70%	99%
A0A0N1PCP5	Leptomonas seymouri	25%	100%
A0A0N1PFD1	Leptomonas seymouri	37%	98%
A0A0S4IV32	Bodo saltans	24%	100%
A0A0S4JBX6	Bodo saltans	24%	92%
A0A0S4JHM8	Bodo saltans	24%	100%
A0A0S4JPU4	Bodo saltans	23%	100%
A0A0S4JQ87	Bodo saltans	32%	100%
A0A0S4JU02	Bodo saltans	36%	100%
A0A1X0NJR7	Trypanosomatidae	47%	99%
A0A1X0NKS5	Trypanosomatidae	41%	100%
A0A1X0NKV2	Trypanosomatidae	42%	98%
A0A1X0NKW7	Trypanosomatidae	43%	100%
A0A1X0NNX9	Trypanosomatidae	40%	100%
A0A1X0NPV3	Trypanosomatidae	42%	100%
A0A1X0NQH3	Trypanosomatidae	43%	100%
A0A1X0NR26	Trypanosomatidae	40%	100%
A0A1X0NRL3	Trypanosomatidae	43%	100%
A0A1X0NRL7	Trypanosomatidae	39%	100%
A0A1X0NYI3	Trypanosomatidae	56%	99%
A0A1X0P4S1	Trypanosomatidae	25%	100%
A0A1X0P814	Trypanosomatidae	37%	100%
A0A1X0P9N8	Trypanosomatidae	27%	100%
A0A381MBS1	Leishmania infantum	21%	100%
A0A3Q8IB21	Leishmania donovani	21%	100%
A0A3Q8ICL1	Leishmania donovani	37%	81%
A0A3Q8ID74	Leishmania donovani	39%	100%
A0A3Q8IDG8	Leishmania donovani	46%	100%
A0A3Q8IEP8	Leishmania donovani	46%	100%
A0A3Q8IFZ0	Leishmania donovani	43%	100%
A0A3Q8IG00	Leishmania donovani	40%	100%
A0A3Q8IGE6	Leishmania donovani	36%	84%
A0A3Q8IHG8	Leishmania donovani	41%	100%
A0A3Q8IJH2	Leishmania donovani	43%	100%
A0A3Q8IJX8	Leishmania donovani	37%	96%
A0A3Q8ILE0	Leishmania donovani	43%	100%
A0A3Q8IQG8	Leishmania donovani	31%	100%
A0A3R7JSA0	Trypanosoma rangeli	37%	100%
A0A3R7KDS3	Trypanosoma rangeli	38%	100%
A0A3R7MQD8	Trypanosoma rangeli	22%	100%
A0A3R7MWF1	Trypanosoma rangeli	27%	100%
A0A3R7N1H9	Trypanosoma rangeli	37%	100%
A0A3R7N2A2	Trypanosoma rangeli	45%	100%
A0A3R7R2W8	Trypanosoma rangeli	43%	100%
A0A3R7RFB5	Trypanosoma rangeli	40%	97%
A0A3R7RQX3	Trypanosoma rangeli	41%	100%
A0A3S5H6G5	Leishmania donovani	21%	100%
A0A3S5H6T4	Leishmania donovani	45%	100%
A0A3S5H7P4	Leishmania donovani	40%	100%
A0A3S5ISG3	Trypanosoma rangeli	46%	99%
A0A3S7X443	Leishmania donovani	44%	100%
A0A3S7X458	Leishmania donovani	44%	98%
A0A3S7X4A1	Leishmania donovani	39%	100%
A0A3S7X4L2	Leishmania donovani	37%	81%
A0A3S7X4N4	Leishmania donovani	37%	81%
A0A3S7X4P0	Leishmania donovani	37%	81%
A0A3S7XA86	Leishmania donovani	26%	100%
A0A3S7XCE3	Leishmania donovani	21%	100%
A0A422MW74	Trypanosoma rangeli	37%	96%
A0A422N5W8	Trypanosoma rangeli	23%	100%
A0A422N608	Trypanosoma rangeli	40%	100%
A0A422NBM3	Trypanosoma rangeli	45%	100%
A0A422NBQ2	Trypanosoma rangeli	39%	100%
A0A422NZS1	Trypanosoma rangeli	39%	100%
A1YG32	Pan paniscus	23%	97%
A2VCW5	Rattus norvegicus	23%	100%
A2VE31	Bos taurus	21%	97%
A4H565	Leishmania braziliensis	80%	100%
A4HC75	Leishmania braziliensis	42%	100%
A4HFJ2	Leishmania braziliensis	43%	100%
A4HFT5	Leishmania braziliensis	46%	100%
A4HJ06	Leishmania braziliensis	40%	100%
A4HJ07	Leishmania braziliensis	41%	99%
A4HJ09	Leishmania braziliensis	45%	100%
A4HJ10	Leishmania braziliensis	40%	100%
A4HJ35	Leishmania braziliensis	41%	100%
A4HJ36	Leishmania braziliensis	39%	100%
A4HJ37	Leishmania braziliensis	44%	100%
A4HJ63	Leishmania braziliensis	39%	98%
A4HJF8	Leishmania braziliensis	35%	80%
A4HJF9	Leishmania braziliensis	35%	84%
A4HJG1	Leishmania braziliensis	34%	84%
A4HJG3	Leishmania braziliensis	35%	80%
A4HJG5	Leishmania braziliensis	35%	80%
A4HKQ7	Leishmania braziliensis	41%	100%
A4HNJ6	Leishmania braziliensis	27%	100%
A4HNJ7	Leishmania braziliensis	27%	100%
A4HNQ0	Leishmania braziliensis	29%	100%
A4HTE2	Leishmania infantum	99%	100%
A4HUI4	Leishmania infantum	22%	100%
A4HZQ0	Leishmania infantum	43%	100%
A4I2V2	Leishmania infantum	39%	83%
A4I6F1	Leishmania infantum	40%	100%
A4I6F2	Leishmania infantum	46%	100%
A4I6I1	Leishmania infantum	36%	96%
A4I6J8	Leishmania infantum	38%	100%
A4I6J9	Leishmania infantum	45%	100%
A4I6K0	Leishmania infantum	42%	100%
A4I6L3	Leishmania infantum	40%	100%
A4I6L4	Leishmania infantum	36%	96%
A4I6W4	Leishmania infantum	37%	81%
A4I887	Leishmania infantum	43%	100%
A4IC53	Leishmania infantum	26%	100%
A4IC66	Leishmania infantum	28%	100%
A4ICC3	Leishmania infantum	22%	100%
A4ICU5	Leishmania infantum	31%	100%
A6NNN8	Homo sapiens	25%	100%
A7E3U5	Bos taurus	24%	100%
C9ZMB9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
C9ZMD1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	100%
C9ZMD2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
C9ZMD3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	100%
C9ZMD4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	100%
C9ZN51	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	100%
C9ZN59	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	100%
C9ZN60	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	100%
C9ZVS1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	94%
C9ZVS2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	91%
C9ZVS3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	93%
C9ZWQ7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	100%
C9ZWQ8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	100%
C9ZWQ9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	100%
C9ZWR0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	100%
C9ZWR1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	35%	90%
C9ZWR7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	100%
C9ZWX2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
C9ZWX3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
C9ZWX4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	100%
C9ZWX5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	100%
C9ZWX6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
C9ZWX7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
C9ZWY0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	100%
C9ZWY1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	100%
D0A362	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
D0AAF6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	100%
D0AAF8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	100%
D0AAG7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	99%
D0AAG8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	99%
D3Z813	Rattus norvegicus	24%	100%
E8NHF9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	45%	100%
E8NHS7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	36%	85%
E9AD44	Leishmania major	45%	100%
E9AD45	Leishmania major	39%	100%
E9ADD7	Leishmania major	45%	100%
E9AG08	Leishmania major	26%	100%
E9AG09	Leishmania major	28%	100%
E9AHD7	Leishmania infantum	45%	100%
E9AHD9	Leishmania infantum	39%	100%
E9AHL1	Leishmania infantum	37%	81%
E9AHL2	Leishmania infantum	36%	100%
E9AHL3	Leishmania infantum	37%	81%
E9ALD5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
E9AN82	Leishmania mexicana (strain MHOM/GT/2001/U1103)	20%	100%
E9ASF9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	100%
E9AUB8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	100%
E9AVK6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	39%	100%
E9AYW8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	45%	100%
E9AYW9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	100%
E9AZ62	Leishmania mexicana (strain MHOM/GT/2001/U1103)	46%	100%
E9B1I4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	45%	100%
E9B1I6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	42%	100%
E9B1K7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	100%
E9B1K8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	42%	100%
E9B1K9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	47%	100%
E9B1N8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	38%	98%
E9B1N9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	38%	98%
E9B1Y0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	81%
E9B345	Leishmania mexicana (strain MHOM/GT/2001/U1103)	43%	100%
E9B761	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
E9B762	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
F4ILY9	Arabidopsis thaliana	24%	100%
F4IZW8	Arabidopsis thaliana	21%	93%
F4JE35	Arabidopsis thaliana	23%	91%
F4KBM7	Arabidopsis thaliana	25%	100%
G3UVW3	Mus musculus	25%	100%
O74327	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	29%	100%
O80668	Arabidopsis thaliana	23%	92%
P36062	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	21%	71%
P39981	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	21%	100%
Q08AI6	Homo sapiens	25%	100%
Q0WQJ3	Arabidopsis thaliana	22%	100%
Q1PER9	Arabidopsis thaliana	22%	94%
Q28HE5	Xenopus tropicalis	25%	100%
Q3U1J0	Mus musculus	24%	100%
Q3USY0	Mus musculus	25%	100%
Q4KL91	Xenopus laevis	22%	94%
Q4Q072	Leishmania major	22%	100%
Q4Q236	Leishmania major	30%	100%
Q4Q509	Leishmania major	43%	100%
Q4Q680	Leishmania major	37%	81%
Q4Q682	Leishmania major	36%	84%
Q4Q683	Leishmania major	37%	81%
Q4Q6H5	Leishmania major	39%	100%
Q4Q6K5	Leishmania major	45%	100%
Q4Q6K6	Leishmania major	36%	96%
Q4Q6M8	Leishmania major	42%	100%
Q4Q6M9	Leishmania major	45%	100%
Q4Q6N0	Leishmania major	45%	100%
Q4Q6N1	Leishmania major	39%	100%
Q4QBX3	Leishmania major	43%	100%
Q4QHE2	Leishmania major	21%	100%
Q4QHE4	Leishmania major	21%	100%
Q4QIH0	Leishmania major	90%	100%
Q4V8B1	Rattus norvegicus	23%	100%
Q503G8	Danio rerio	24%	100%
Q5E9S9	Bos taurus	23%	100%
Q5EA97	Bos taurus	26%	100%
Q5F468	Gallus gallus	23%	98%
Q5HZH7	Mus musculus	24%	100%
Q5R443	Pongo abelii	23%	100%
Q5R9F5	Pongo abelii	25%	100%
Q5RE87	Pongo abelii	22%	90%
Q5SPB1	Danio rerio	23%	97%
Q5XH90	Xenopus tropicalis	25%	100%
Q6DEL1	Danio rerio	27%	100%
Q6DFE7	Xenopus laevis	27%	100%
Q6JWR2	Rattus norvegicus	25%	100%
Q6WWW3	Rattus norvegicus	25%	100%
Q6YBV0	Homo sapiens	23%	97%
Q8BWH0	Mus musculus	26%	100%
Q8CFE6	Mus musculus	22%	97%
Q8GYS4	Arabidopsis thaliana	23%	89%
Q8HXI3	Macaca fascicularis	24%	100%
Q8IZM9	Homo sapiens	24%	100%
Q8K2P7	Mus musculus	22%	100%
Q8LPF4	Arabidopsis thaliana	24%	93%
Q8WUX1	Homo sapiens	23%	100%
Q969I6	Homo sapiens	22%	90%
Q96QD8	Homo sapiens	23%	97%
Q99624	Homo sapiens	22%	97%
Q9DCP2	Mus musculus	23%	97%
Q9H2H9	Homo sapiens	23%	100%
Q9JHE5	Rattus norvegicus	21%	97%
Q9JHZ9	Rattus norvegicus	23%	97%
Q9JM15	Rattus norvegicus	22%	100%
Q9LI61	Arabidopsis thaliana	24%	100%
Q9LXF8	Arabidopsis thaliana	24%	100%
Q9LYM2	Arabidopsis thaliana	24%	100%
Q9M8L9	Arabidopsis thaliana	25%	100%
Q9NVC3	Homo sapiens	25%	100%
Q9SF09	Arabidopsis thaliana	24%	100%
Q9SS86	Arabidopsis thaliana	22%	100%
Q9SVG0	Arabidopsis thaliana	26%	100%
Q9VT04	Drosophila melanogaster	24%	100%
Q9W056	Drosophila melanogaster	24%	100%
V5AXD0	Trypanosoma cruzi	26%	100%
V5AZP2	Trypanosoma cruzi	45%	81%
V5B9A6	Trypanosoma cruzi	46%	100%
V5BA72	Trypanosoma cruzi	43%	100%
V5BH70	Trypanosoma cruzi	37%	100%
V5BIJ1	Trypanosoma cruzi	41%	88%
V5BMG4	Trypanosoma cruzi	40%	100%
V5BTX5	Trypanosoma cruzi	25%	97%
V5D7K9	Trypanosoma cruzi	56%	100%
V5DCG4	Trypanosoma cruzi	40%	100%
V5DKR4	Trypanosoma cruzi	42%	100%