LeishMANIAdb
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Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hypothetical_protein_conserved
Gene product:
hypothetical protein, unknown function
Species:
Leishmania donovani
UniProt:
A0A3S7WQ31_LEIDO
TriTrypDb:
LdBPK_080050.1 , LdCL_080005400 , LDHU3_08.0060
Length:
75

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WQ31
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WQ31

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_SKI1_1 46 50 PF00082 0.623
DOC_MAPK_gen_1 55 63 PF00069 0.578
DOC_USP7_MATH_1 15 19 PF00917 0.548
DOC_USP7_MATH_1 62 66 PF00917 0.647
DOC_WW_Pin1_4 18 23 PF00397 0.532
LIG_14-3-3_CanoR_1 46 51 PF00244 0.543
LIG_BIR_II_1 1 5 PF00653 0.579
LIG_Pex14_2 30 34 PF04695 0.517
LIG_PTB_Apo_2 28 35 PF02174 0.401
LIG_SH2_STAT5 16 19 PF00017 0.518
LIG_SH2_STAT5 20 23 PF00017 0.536
MOD_CK1_1 18 24 PF00069 0.531
MOD_CK1_1 53 59 PF00069 0.617
MOD_CK1_1 65 71 PF00069 0.637
MOD_GlcNHglycan 17 20 PF01048 0.525
MOD_GlcNHglycan 22 25 PF01048 0.527
MOD_GSK3_1 46 53 PF00069 0.551
MOD_GSK3_1 62 69 PF00069 0.649
MOD_PKA_2 9 15 PF00069 0.494
MOD_Plk_2-3 66 72 PF00069 0.685
MOD_Plk_4 46 52 PF00069 0.549
MOD_ProDKin_1 18 24 PF00069 0.534
MOD_SUMO_rev_2 23 30 PF00179 0.505

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1ICC7 Leptomonas seymouri 78% 100%
A4H572 Leishmania braziliensis 83% 100%
A4HTF5 Leishmania infantum 100% 100%
E9AM83 Leishmania mexicana (strain MHOM/GT/2001/U1103) 91% 100%
Q4QIG4 Leishmania major 89% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS