ATP-dependent DNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

PIF1 helicase-like protein, putative

Species:

Leishmania donovani

UniProt:

A0A3S7WQ25_LEIDO

TriTrypDb:

LdBPK_071170.1 , LdCL_070016500 , LDHU3_07.1380

Length:

1219

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	6
GO:0110165	cellular anatomical entity	1	7
GO:0005657	replication fork	2	1
GO:0005739	mitochondrion	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1

Expansion

Sequence features

A0A3S7WQ25

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WQ25

Function

Biological processes
Term	Name	Level	Count
GO:0000723	telomere maintenance	5	7
GO:0006139	nucleobase-containing compound metabolic process	3	7
GO:0006259	DNA metabolic process	4	7
GO:0006281	DNA repair	5	7
GO:0006310	DNA recombination	5	7
GO:0006725	cellular aromatic compound metabolic process	3	7
GO:0006807	nitrogen compound metabolic process	2	7
GO:0006950	response to stress	2	7
GO:0006974	DNA damage response	4	7
GO:0006996	organelle organization	4	7
GO:0008152	metabolic process	1	7
GO:0009987	cellular process	1	7
GO:0016043	cellular component organization	3	7
GO:0032200	telomere organization	6	7
GO:0033554	cellular response to stress	3	7
GO:0034641	cellular nitrogen compound metabolic process	3	7
GO:0043170	macromolecule metabolic process	3	7
GO:0044237	cellular metabolic process	2	7
GO:0044238	primary metabolic process	2	7
GO:0044260	obsolete cellular macromolecule metabolic process	3	7
GO:0046483	heterocycle metabolic process	3	7
GO:0050896	response to stimulus	1	7
GO:0051276	chromosome organization	5	7
GO:0051716	cellular response to stimulus	2	7
GO:0071704	organic substance metabolic process	2	7
GO:0071840	cellular component organization or biogenesis	2	7
GO:0090304	nucleic acid metabolic process	4	7
GO:1901360	organic cyclic compound metabolic process	3	7
GO:0006260	DNA replication	5	1
GO:0032392	DNA geometric change	7	1
GO:0032508	DNA duplex unwinding	8	1
GO:0071103	DNA conformation change	6	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	7
GO:0003678	DNA helicase activity	3	7
GO:0003824	catalytic activity	1	7
GO:0004386	helicase activity	2	7
GO:0005488	binding	1	7
GO:0005524	ATP binding	5	7
GO:0008094	ATP-dependent activity, acting on DNA	2	7
GO:0016462	pyrophosphatase activity	5	7
GO:0016787	hydrolase activity	2	7
GO:0016817	hydrolase activity, acting on acid anhydrides	3	7
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	7
GO:0016887	ATP hydrolysis activity	7	7
GO:0017076	purine nucleotide binding	4	7
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	7
GO:0030554	adenyl nucleotide binding	5	7
GO:0032553	ribonucleotide binding	3	7
GO:0032555	purine ribonucleotide binding	4	7
GO:0032559	adenyl ribonucleotide binding	5	7
GO:0035639	purine ribonucleoside triphosphate binding	4	7
GO:0036094	small molecule binding	2	7
GO:0043167	ion binding	2	7
GO:0043168	anion binding	3	7
GO:0097159	organic cyclic compound binding	2	7
GO:0097367	carbohydrate derivative binding	2	7
GO:0140097	catalytic activity, acting on DNA	3	7
GO:0140640	catalytic activity, acting on a nucleic acid	2	7
GO:0140657	ATP-dependent activity	1	7
GO:1901265	nucleoside phosphate binding	3	7
GO:1901363	heterocyclic compound binding	2	7
GO:0000287	magnesium ion binding	5	1
GO:0043169	cation binding	3	1
GO:0046872	metal ion binding	4	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1043	1047	PF00656	0.718
CLV_C14_Caspase3-7	1212	1216	PF00656	0.662
CLV_C14_Caspase3-7	130	134	PF00656	0.546
CLV_C14_Caspase3-7	2	6	PF00656	0.738
CLV_C14_Caspase3-7	330	334	PF00656	0.513
CLV_C14_Caspase3-7	585	589	PF00656	0.563
CLV_C14_Caspase3-7	873	877	PF00656	0.733
CLV_C14_Caspase3-7	914	918	PF00656	0.760
CLV_NRD_NRD_1	19	21	PF00675	0.735
CLV_NRD_NRD_1	407	409	PF00675	0.411
CLV_NRD_NRD_1	475	477	PF00675	0.649
CLV_NRD_NRD_1	527	529	PF00675	0.708
CLV_NRD_NRD_1	597	599	PF00675	0.467
CLV_NRD_NRD_1	784	786	PF00675	0.656
CLV_NRD_NRD_1	79	81	PF00675	0.688
CLV_NRD_NRD_1	874	876	PF00675	0.769
CLV_NRD_NRD_1	886	888	PF00675	0.623
CLV_NRD_NRD_1	942	944	PF00675	0.612
CLV_PCSK_FUR_1	405	409	PF00082	0.513
CLV_PCSK_FUR_1	782	786	PF00082	0.721
CLV_PCSK_KEX2_1	19	21	PF00082	0.735
CLV_PCSK_KEX2_1	407	409	PF00082	0.411
CLV_PCSK_KEX2_1	475	477	PF00082	0.649
CLV_PCSK_KEX2_1	500	502	PF00082	0.700
CLV_PCSK_KEX2_1	527	529	PF00082	0.708
CLV_PCSK_KEX2_1	784	786	PF00082	0.656
CLV_PCSK_KEX2_1	79	81	PF00082	0.688
CLV_PCSK_KEX2_1	874	876	PF00082	0.779
CLV_PCSK_KEX2_1	885	887	PF00082	0.656
CLV_PCSK_KEX2_1	941	943	PF00082	0.630
CLV_PCSK_KEX2_1	955	957	PF00082	0.593
CLV_PCSK_PC1ET2_1	500	502	PF00082	0.700
CLV_PCSK_PC1ET2_1	955	957	PF00082	0.571
CLV_PCSK_PC7_1	496	502	PF00082	0.806
CLV_PCSK_PC7_1	780	786	PF00082	0.710
CLV_PCSK_SKI1_1	1124	1128	PF00082	0.678
CLV_PCSK_SKI1_1	1158	1162	PF00082	0.648
CLV_PCSK_SKI1_1	1164	1168	PF00082	0.480
CLV_PCSK_SKI1_1	260	264	PF00082	0.465
CLV_PCSK_SKI1_1	271	275	PF00082	0.343
CLV_PCSK_SKI1_1	602	606	PF00082	0.489
CLV_PCSK_SKI1_1	690	694	PF00082	0.692
CLV_PCSK_SKI1_1	730	734	PF00082	0.541
CLV_PCSK_SKI1_1	79	83	PF00082	0.814
CLV_PCSK_SKI1_1	956	960	PF00082	0.626
CLV_Separin_Metazoa	493	497	PF03568	0.636
DEG_APCC_DBOX_1	527	535	PF00400	0.527
DEG_SPOP_SBC_1	837	841	PF00917	0.760
DOC_CKS1_1	1	6	PF01111	0.744
DOC_CKS1_1	120	125	PF01111	0.620
DOC_CKS1_1	245	250	PF01111	0.546
DOC_CKS1_1	431	436	PF01111	0.416
DOC_CYCLIN_RxL_1	769	779	PF00134	0.589
DOC_CYCLIN_RxL_1	77	87	PF00134	0.717
DOC_MAPK_DCC_7	659	668	PF00069	0.443
DOC_MAPK_gen_1	1086	1095	PF00069	0.532
DOC_MAPK_gen_1	178	185	PF00069	0.799
DOC_MAPK_gen_1	328	338	PF00069	0.389
DOC_MAPK_gen_1	347	357	PF00069	0.411
DOC_MAPK_gen_1	527	533	PF00069	0.683
DOC_MAPK_gen_1	598	606	PF00069	0.476
DOC_MAPK_gen_1	939	947	PF00069	0.501
DOC_MAPK_gen_1	967	975	PF00069	0.446
DOC_MAPK_MEF2A_6	1113	1120	PF00069	0.562
DOC_MAPK_MEF2A_6	331	340	PF00069	0.436
DOC_MAPK_MEF2A_6	423	430	PF00069	0.411
DOC_MAPK_MEF2A_6	607	615	PF00069	0.570
DOC_MAPK_MEF2A_6	659	668	PF00069	0.439
DOC_MAPK_MEF2A_6	700	708	PF00069	0.450
DOC_PP1_RVXF_1	1145	1152	PF00149	0.602
DOC_PP1_RVXF_1	436	443	PF00149	0.492
DOC_PP1_RVXF_1	468	474	PF00149	0.727
DOC_PP1_RVXF_1	778	784	PF00149	0.587
DOC_PP2B_LxvP_1	38	41	PF13499	0.649
DOC_PP2B_LxvP_1	398	401	PF13499	0.411
DOC_PP4_FxxP_1	1066	1069	PF00568	0.574
DOC_PP4_FxxP_1	121	124	PF00568	0.713
DOC_SPAK_OSR1_1	1113	1117	PF12202	0.605
DOC_USP7_MATH_1	1019	1023	PF00917	0.552
DOC_USP7_MATH_1	140	144	PF00917	0.733
DOC_USP7_MATH_1	147	151	PF00917	0.675
DOC_USP7_MATH_1	18	22	PF00917	0.728
DOC_USP7_MATH_1	201	205	PF00917	0.729
DOC_USP7_MATH_1	240	244	PF00917	0.756
DOC_USP7_MATH_1	254	258	PF00917	0.336
DOC_USP7_MATH_1	293	297	PF00917	0.457
DOC_USP7_MATH_1	503	507	PF00917	0.705
DOC_USP7_MATH_1	510	514	PF00917	0.641
DOC_USP7_MATH_1	587	591	PF00917	0.469
DOC_USP7_MATH_1	837	841	PF00917	0.760
DOC_USP7_UBL2_3	1127	1131	PF12436	0.667
DOC_USP7_UBL2_3	868	872	PF12436	0.728
DOC_WW_Pin1_4	1029	1034	PF00397	0.689
DOC_WW_Pin1_4	111	116	PF00397	0.652
DOC_WW_Pin1_4	119	124	PF00397	0.682
DOC_WW_Pin1_4	136	141	PF00397	0.620
DOC_WW_Pin1_4	14	19	PF00397	0.729
DOC_WW_Pin1_4	197	202	PF00397	0.838
DOC_WW_Pin1_4	244	249	PF00397	0.562
DOC_WW_Pin1_4	408	413	PF00397	0.513
DOC_WW_Pin1_4	430	435	PF00397	0.416
DOC_WW_Pin1_4	59	64	PF00397	0.704
DOC_WW_Pin1_4	801	806	PF00397	0.758
DOC_WW_Pin1_4	843	848	PF00397	0.762
DOC_WW_Pin1_4	91	96	PF00397	0.664
LIG_14-3-3_CanoR_1	1113	1117	PF00244	0.580
LIG_14-3-3_CanoR_1	19	24	PF00244	0.735
LIG_14-3-3_CanoR_1	253	263	PF00244	0.436
LIG_14-3-3_CanoR_1	344	350	PF00244	0.433
LIG_14-3-3_CanoR_1	436	441	PF00244	0.397
LIG_14-3-3_CanoR_1	567	576	PF00244	0.520
LIG_14-3-3_CanoR_1	659	663	PF00244	0.454
LIG_14-3-3_CanoR_1	744	751	PF00244	0.496
LIG_14-3-3_CanoR_1	760	768	PF00244	0.492
LIG_14-3-3_CanoR_1	782	792	PF00244	0.692
LIG_14-3-3_CanoR_1	845	854	PF00244	0.748
LIG_14-3-3_CanoR_1	90	95	PF00244	0.781
LIG_BIR_III_4	1141	1145	PF00653	0.657
LIG_BIR_III_4	5	9	PF00653	0.757
LIG_BRCT_BRCA1_1	296	300	PF00533	0.411
LIG_BRCT_BRCA1_1	393	397	PF00533	0.411
LIG_BRCT_BRCA1_1	410	414	PF00533	0.411
LIG_BRCT_BRCA1_1	431	435	PF00533	0.411
LIG_BRCT_BRCA1_1	438	442	PF00533	0.506
LIG_BRCT_BRCA1_1	829	833	PF00533	0.635
LIG_deltaCOP1_diTrp_1	1108	1114	PF00928	0.550
LIG_EVH1_1	72	76	PF00568	0.675
LIG_FHA_1	1099	1105	PF00498	0.539
LIG_FHA_1	1113	1119	PF00498	0.579
LIG_FHA_1	1183	1189	PF00498	0.446
LIG_FHA_1	30	36	PF00498	0.765
LIG_FHA_1	302	308	PF00498	0.438
LIG_FHA_1	349	355	PF00498	0.436
LIG_FHA_1	466	472	PF00498	0.589
LIG_FHA_1	590	596	PF00498	0.550
LIG_FHA_1	618	624	PF00498	0.515
LIG_FHA_1	63	69	PF00498	0.695
LIG_FHA_1	635	641	PF00498	0.521
LIG_FHA_1	677	683	PF00498	0.558
LIG_FHA_1	932	938	PF00498	0.652
LIG_FHA_2	128	134	PF00498	0.700
LIG_FHA_2	203	209	PF00498	0.740
LIG_FHA_2	37	43	PF00498	0.807
LIG_FHA_2	527	533	PF00498	0.723
LIG_FHA_2	552	558	PF00498	0.511
LIG_FHA_2	620	626	PF00498	0.587
LIG_FHA_2	652	658	PF00498	0.606
LIG_FHA_2	721	727	PF00498	0.602
LIG_FHA_2	744	750	PF00498	0.425
LIG_FHA_2	933	939	PF00498	0.535
LIG_GBD_Chelix_1	533	541	PF00786	0.476
LIG_Integrin_RGD_1	1044	1046	PF01839	0.606
LIG_LIR_Apic_2	1064	1069	PF02991	0.587
LIG_LIR_Apic_2	119	124	PF02991	0.717
LIG_LIR_Apic_2	89	95	PF02991	0.755
LIG_LIR_Gen_1	1108	1119	PF02991	0.557
LIG_LIR_Gen_1	366	375	PF02991	0.389
LIG_LIR_Gen_1	394	403	PF02991	0.411
LIG_LIR_Gen_1	546	556	PF02991	0.509
LIG_LIR_Gen_1	624	634	PF02991	0.507
LIG_LIR_Gen_1	830	837	PF02991	0.594
LIG_LIR_Gen_1	861	870	PF02991	0.587
LIG_LIR_LC3C_4	679	684	PF02991	0.616
LIG_LIR_Nem_3	1108	1114	PF02991	0.570
LIG_LIR_Nem_3	1168	1172	PF02991	0.452
LIG_LIR_Nem_3	364	370	PF02991	0.411
LIG_LIR_Nem_3	384	389	PF02991	0.411
LIG_LIR_Nem_3	394	400	PF02991	0.411
LIG_LIR_Nem_3	418	424	PF02991	0.410
LIG_LIR_Nem_3	439	445	PF02991	0.433
LIG_LIR_Nem_3	542	548	PF02991	0.546
LIG_LIR_Nem_3	563	569	PF02991	0.489
LIG_LIR_Nem_3	624	629	PF02991	0.477
LIG_LIR_Nem_3	726	732	PF02991	0.489
LIG_LIR_Nem_3	738	742	PF02991	0.454
LIG_LIR_Nem_3	804	809	PF02991	0.656
LIG_LIR_Nem_3	830	836	PF02991	0.751
LIG_LIR_Nem_3	861	867	PF02991	0.585
LIG_Pex14_2	729	733	PF04695	0.509
LIG_Pex14_2	829	833	PF04695	0.635
LIG_Pex14_2	993	997	PF04695	0.524
LIG_SH2_CRK	548	552	PF00017	0.480
LIG_SH2_CRK	566	570	PF00017	0.514
LIG_SH2_CRK	771	775	PF00017	0.511
LIG_SH2_CRK	806	810	PF00017	0.681
LIG_SH2_CRK	92	96	PF00017	0.762
LIG_SH2_NCK_1	92	96	PF00017	0.762
LIG_SH2_PTP2	739	742	PF00017	0.454
LIG_SH2_PTP2	808	811	PF00017	0.659
LIG_SH2_STAP1	1169	1173	PF00017	0.446
LIG_SH2_STAP1	1193	1197	PF00017	0.466
LIG_SH2_STAP1	261	265	PF00017	0.411
LIG_SH2_STAP1	710	714	PF00017	0.447
LIG_SH2_STAT3	565	568	PF00017	0.603
LIG_SH2_STAT5	1172	1175	PF00017	0.566
LIG_SH2_STAT5	1206	1209	PF00017	0.670
LIG_SH2_STAT5	373	376	PF00017	0.411
LIG_SH2_STAT5	548	551	PF00017	0.480
LIG_SH2_STAT5	633	636	PF00017	0.621
LIG_SH2_STAT5	739	742	PF00017	0.454
LIG_SH2_STAT5	808	811	PF00017	0.659
LIG_SH2_STAT5	92	95	PF00017	0.761
LIG_SH3_1	379	385	PF00018	0.411
LIG_SH3_3	1030	1036	PF00018	0.697
LIG_SH3_3	1092	1098	PF00018	0.518
LIG_SH3_3	1113	1119	PF00018	0.617
LIG_SH3_3	117	123	PF00018	0.683
LIG_SH3_3	12	18	PF00018	0.757
LIG_SH3_3	139	145	PF00018	0.823
LIG_SH3_3	20	26	PF00018	0.621
LIG_SH3_3	236	242	PF00018	0.825
LIG_SH3_3	379	385	PF00018	0.411
LIG_SH3_3	68	74	PF00018	0.737
LIG_SH3_3	680	686	PF00018	0.494
LIG_SH3_3	699	705	PF00018	0.450
LIG_SH3_3	981	987	PF00018	0.647
LIG_SUMO_SIM_anti_2	1079	1085	PF11976	0.506
LIG_SUMO_SIM_anti_2	30	39	PF11976	0.594
LIG_SUMO_SIM_anti_2	333	341	PF11976	0.436
LIG_SUMO_SIM_anti_2	457	464	PF11976	0.522
LIG_SUMO_SIM_anti_2	529	535	PF11976	0.726
LIG_SUMO_SIM_par_1	116	122	PF11976	0.629
LIG_SUMO_SIM_par_1	25	33	PF11976	0.708
LIG_SUMO_SIM_par_1	353	359	PF11976	0.513
LIG_TRAF2_2	1033	1038	PF00917	0.696
LIG_TYR_ITSM	802	809	PF00017	0.651
LIG_UBA3_1	335	342	PF00899	0.389
LIG_WRC_WIRS_1	317	322	PF05994	0.411
LIG_WRC_WIRS_1	626	631	PF05994	0.497
LIG_WRC_WIRS_1	833	838	PF05994	0.733
LIG_WW_2	73	76	PF00397	0.663
MOD_CDC14_SPxK_1	17	20	PF00782	0.731
MOD_CDK_SPK_2	14	19	PF00069	0.792
MOD_CDK_SPxK_1	14	20	PF00069	0.735
MOD_CDK_SPxK_1	430	436	PF00069	0.416
MOD_CK1_1	109	115	PF00069	0.654
MOD_CK1_1	116	122	PF00069	0.728
MOD_CK1_1	150	156	PF00069	0.671
MOD_CK1_1	204	210	PF00069	0.810
MOD_CK1_1	296	302	PF00069	0.299
MOD_CK1_1	313	319	PF00069	0.375
MOD_CK1_1	327	333	PF00069	0.411
MOD_CK1_1	334	340	PF00069	0.459
MOD_CK1_1	348	354	PF00069	0.232
MOD_CK1_1	464	470	PF00069	0.561
MOD_CK1_1	52	58	PF00069	0.728
MOD_CK1_1	522	528	PF00069	0.693
MOD_CK1_1	589	595	PF00069	0.528
MOD_CK1_1	619	625	PF00069	0.482
MOD_CK1_1	62	68	PF00069	0.705
MOD_CK1_1	735	741	PF00069	0.494
MOD_CK1_1	743	749	PF00069	0.452
MOD_CK1_1	832	838	PF00069	0.781
MOD_CK1_1	84	90	PF00069	0.705
MOD_CK1_1	840	846	PF00069	0.698
MOD_CK1_1	921	927	PF00069	0.783
MOD_CK1_1	94	100	PF00069	0.765
MOD_CK2_1	1019	1025	PF00069	0.580
MOD_CK2_1	1173	1179	PF00069	0.523
MOD_CK2_1	163	169	PF00069	0.828
MOD_CK2_1	202	208	PF00069	0.831
MOD_CK2_1	210	216	PF00069	0.770
MOD_CK2_1	27	33	PF00069	0.700
MOD_CK2_1	358	364	PF00069	0.411
MOD_CK2_1	36	42	PF00069	0.681
MOD_CK2_1	526	532	PF00069	0.766
MOD_CK2_1	551	557	PF00069	0.450
MOD_CK2_1	743	749	PF00069	0.422
MOD_CK2_1	83	89	PF00069	0.781
MOD_GlcNHglycan	1210	1214	PF01048	0.746
MOD_GlcNHglycan	149	152	PF01048	0.723
MOD_GlcNHglycan	192	195	PF01048	0.699
MOD_GlcNHglycan	242	245	PF01048	0.685
MOD_GlcNHglycan	312	315	PF01048	0.411
MOD_GlcNHglycan	393	396	PF01048	0.411
MOD_GlcNHglycan	504	508	PF01048	0.707
MOD_GlcNHglycan	512	515	PF01048	0.648
MOD_GlcNHglycan	520	524	PF01048	0.678
MOD_GlcNHglycan	640	643	PF01048	0.529
MOD_GlcNHglycan	734	737	PF01048	0.575
MOD_GlcNHglycan	761	764	PF01048	0.446
MOD_GlcNHglycan	901	906	PF01048	0.685
MOD_GlcNHglycan	988	991	PF01048	0.564
MOD_GSK3_1	1019	1026	PF00069	0.580
MOD_GSK3_1	1050	1057	PF00069	0.696
MOD_GSK3_1	106	113	PF00069	0.616
MOD_GSK3_1	136	143	PF00069	0.639
MOD_GSK3_1	14	21	PF00069	0.760
MOD_GSK3_1	152	159	PF00069	0.641
MOD_GSK3_1	197	204	PF00069	0.772
MOD_GSK3_1	210	217	PF00069	0.703
MOD_GSK3_1	240	247	PF00069	0.588
MOD_GSK3_1	25	32	PF00069	0.685
MOD_GSK3_1	269	276	PF00069	0.513
MOD_GSK3_1	312	319	PF00069	0.338
MOD_GSK3_1	327	334	PF00069	0.411
MOD_GSK3_1	461	468	PF00069	0.522
MOD_GSK3_1	474	481	PF00069	0.668
MOD_GSK3_1	52	59	PF00069	0.728
MOD_GSK3_1	522	529	PF00069	0.713
MOD_GSK3_1	546	553	PF00069	0.472
MOD_GSK3_1	617	624	PF00069	0.491
MOD_GSK3_1	634	641	PF00069	0.525
MOD_GSK3_1	692	699	PF00069	0.609
MOD_GSK3_1	710	717	PF00069	0.336
MOD_GSK3_1	743	750	PF00069	0.574
MOD_GSK3_1	759	766	PF00069	0.428
MOD_GSK3_1	824	831	PF00069	0.745
MOD_GSK3_1	832	839	PF00069	0.677
MOD_GSK3_1	90	97	PF00069	0.801
MOD_GSK3_1	901	908	PF00069	0.677
MOD_LATS_1	161	167	PF00433	0.651
MOD_N-GLC_1	310	315	PF02516	0.411
MOD_N-GLC_1	616	621	PF02516	0.506
MOD_N-GLC_1	931	936	PF02516	0.705
MOD_NEK2_1	1027	1032	PF00069	0.602
MOD_NEK2_1	1040	1045	PF00069	0.524
MOD_NEK2_1	1071	1076	PF00069	0.634
MOD_NEK2_1	108	113	PF00069	0.765
MOD_NEK2_1	1112	1117	PF00069	0.602
MOD_NEK2_1	1173	1178	PF00069	0.490
MOD_NEK2_1	27	32	PF00069	0.706
MOD_NEK2_1	286	291	PF00069	0.513
MOD_NEK2_1	310	315	PF00069	0.408
MOD_NEK2_1	521	526	PF00069	0.775
MOD_NEK2_1	551	556	PF00069	0.460
MOD_NEK2_1	56	61	PF00069	0.716
MOD_NEK2_1	634	639	PF00069	0.533
MOD_NEK2_1	720	725	PF00069	0.512
MOD_NEK2_1	82	87	PF00069	0.741
MOD_NEK2_1	829	834	PF00069	0.762
MOD_NEK2_1	836	841	PF00069	0.748
MOD_NEK2_1	931	936	PF00069	0.760
MOD_NEK2_1	947	952	PF00069	0.429
MOD_NEK2_2	1050	1055	PF00069	0.697
MOD_NEK2_2	156	161	PF00069	0.643
MOD_NEK2_2	710	715	PF00069	0.453
MOD_OFUCOSY	345	352	PF10250	0.436
MOD_PIKK_1	1025	1031	PF00454	0.683
MOD_PIKK_1	634	640	PF00454	0.552
MOD_PIKK_1	714	720	PF00454	0.507
MOD_PIKK_1	880	886	PF00454	0.768
MOD_PK_1	1200	1206	PF00069	0.444
MOD_PK_1	19	25	PF00069	0.736
MOD_PKA_1	19	25	PF00069	0.736
MOD_PKA_1	407	413	PF00069	0.513
MOD_PKA_2	1040	1046	PF00069	0.684
MOD_PKA_2	1054	1060	PF00069	0.514
MOD_PKA_2	1112	1118	PF00069	0.574
MOD_PKA_2	127	133	PF00069	0.788
MOD_PKA_2	18	24	PF00069	0.731
MOD_PKA_2	327	333	PF00069	0.411
MOD_PKA_2	407	413	PF00069	0.513
MOD_PKA_2	474	480	PF00069	0.690
MOD_PKA_2	526	532	PF00069	0.734
MOD_PKA_2	551	557	PF00069	0.509
MOD_PKA_2	651	657	PF00069	0.587
MOD_PKA_2	658	664	PF00069	0.470
MOD_PKA_2	743	749	PF00069	0.495
MOD_PKA_2	759	765	PF00069	0.509
MOD_PKA_2	783	789	PF00069	0.686
MOD_PKA_2	824	830	PF00069	0.804
MOD_PKA_2	968	974	PF00069	0.482
MOD_PKB_1	1198	1206	PF00069	0.504
MOD_PKB_1	405	413	PF00069	0.513
MOD_Plk_1	358	364	PF00069	0.411
MOD_Plk_1	587	593	PF00069	0.594
MOD_Plk_1	932	938	PF00069	0.743
MOD_Plk_2-3	358	364	PF00069	0.411
MOD_Plk_4	1009	1015	PF00069	0.600
MOD_Plk_4	113	119	PF00069	0.776
MOD_Plk_4	1184	1190	PF00069	0.446
MOD_Plk_4	296	302	PF00069	0.353
MOD_Plk_4	316	322	PF00069	0.396
MOD_Plk_4	331	337	PF00069	0.450
MOD_Plk_4	358	364	PF00069	0.411
MOD_Plk_4	546	552	PF00069	0.496
MOD_Plk_4	651	657	PF00069	0.587
MOD_Plk_4	658	664	PF00069	0.470
MOD_Plk_4	735	741	PF00069	0.559
MOD_ProDKin_1	1029	1035	PF00069	0.692
MOD_ProDKin_1	111	117	PF00069	0.653
MOD_ProDKin_1	119	125	PF00069	0.683
MOD_ProDKin_1	136	142	PF00069	0.614
MOD_ProDKin_1	14	20	PF00069	0.730
MOD_ProDKin_1	197	203	PF00069	0.839
MOD_ProDKin_1	244	250	PF00069	0.553
MOD_ProDKin_1	408	414	PF00069	0.513
MOD_ProDKin_1	430	436	PF00069	0.416
MOD_ProDKin_1	59	65	PF00069	0.708
MOD_ProDKin_1	801	807	PF00069	0.759
MOD_ProDKin_1	843	849	PF00069	0.760
MOD_ProDKin_1	91	97	PF00069	0.666
MOD_SUMO_for_1	483	486	PF00179	0.772
MOD_SUMO_for_1	854	857	PF00179	0.761
MOD_SUMO_rev_2	685	692	PF00179	0.584
MOD_SUMO_rev_2	726	732	PF00179	0.513
TRG_DiLeu_BaEn_1	103	108	PF01217	0.725
TRG_DiLeu_BaEn_2	468	474	PF01217	0.727
TRG_DiLeu_BaLyEn_6	1066	1071	PF01217	0.584
TRG_DiLeu_BaLyEn_6	1116	1121	PF01217	0.575
TRG_DiLeu_BaLyEn_6	702	707	PF01217	0.544
TRG_DiLeu_BaLyEn_6	943	948	PF01217	0.600
TRG_ENDOCYTIC_2	182	185	PF00928	0.705
TRG_ENDOCYTIC_2	548	551	PF00928	0.480
TRG_ENDOCYTIC_2	566	569	PF00928	0.501
TRG_ENDOCYTIC_2	576	579	PF00928	0.429
TRG_ENDOCYTIC_2	739	742	PF00928	0.454
TRG_ENDOCYTIC_2	771	774	PF00928	0.506
TRG_ENDOCYTIC_2	806	809	PF00928	0.662
TRG_ER_diArg_1	1121	1124	PF00400	0.633
TRG_ER_diArg_1	1197	1200	PF00400	0.507
TRG_ER_diArg_1	178	181	PF00400	0.703
TRG_ER_diArg_1	18	20	PF00400	0.729
TRG_ER_diArg_1	378	381	PF00400	0.411
TRG_ER_diArg_1	435	438	PF00400	0.411
TRG_ER_diArg_1	474	476	PF00400	0.592
TRG_ER_diArg_1	526	528	PF00400	0.578
TRG_ER_diArg_1	780	783	PF00400	0.592
TRG_ER_diArg_1	79	81	PF00400	0.688
TRG_ER_diArg_1	885	887	PF00400	0.826
TRG_ER_diArg_1	940	943	PF00400	0.628
TRG_ER_FFAT_2	86	97	PF00635	0.657
TRG_Pf-PMV_PEXEL_1	1164	1168	PF00026	0.478
TRG_Pf-PMV_PEXEL_1	163	167	PF00026	0.809
TRG_Pf-PMV_PEXEL_1	212	216	PF00026	0.643
TRG_Pf-PMV_PEXEL_1	253	258	PF00026	0.436
TRG_Pf-PMV_PEXEL_1	353	358	PF00026	0.411
TRG_Pf-PMV_PEXEL_1	567	572	PF00026	0.496
TRG_Pf-PMV_PEXEL_1	680	685	PF00026	0.600

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3C2	Leptomonas seymouri	55%	98%
A4H550	Leishmania braziliensis	71%	100%
A4HTC6	Leishmania infantum	99%	100%
E9ALB9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4QII5	Leishmania major	91%	100%