Sel1 repeat, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7WQ08_LEIDO

TriTrypDb:

LdBPK_071200.1 , LdCL_070016900 , LDHU3_07.1420

Length:

324

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WQ08

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WQ08

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	166	170	PF00656	0.446
CLV_C14_Caspase3-7	93	97	PF00656	0.442
CLV_NRD_NRD_1	85	87	PF00675	0.610
CLV_PCSK_KEX2_1	316	318	PF00082	0.414
CLV_PCSK_KEX2_1	85	87	PF00082	0.622
CLV_PCSK_PC1ET2_1	316	318	PF00082	0.358
CLV_PCSK_SKI1_1	196	200	PF00082	0.408
CLV_PCSK_SKI1_1	269	273	PF00082	0.449
CLV_PCSK_SKI1_1	313	317	PF00082	0.500
DOC_CYCLIN_RxL_1	266	276	PF00134	0.455
DOC_CYCLIN_yCln2_LP_2	134	140	PF00134	0.415
DOC_CYCLIN_yCln2_LP_2	46	52	PF00134	0.408
DOC_PP2B_LxvP_1	10	13	PF13499	0.545
DOC_PP2B_LxvP_1	56	59	PF13499	0.371
DOC_USP7_MATH_1	11	15	PF00917	0.693
DOC_USP7_MATH_1	179	183	PF00917	0.518
DOC_USP7_MATH_1	198	202	PF00917	0.491
DOC_USP7_MATH_1	208	212	PF00917	0.441
DOC_USP7_MATH_1	229	233	PF00917	0.626
DOC_USP7_MATH_1	34	38	PF00917	0.539
DOC_WW_Pin1_4	133	138	PF00397	0.584
DOC_WW_Pin1_4	14	19	PF00397	0.710
LIG_14-3-3_CanoR_1	206	215	PF00244	0.498
LIG_14-3-3_CanoR_1	86	92	PF00244	0.582
LIG_APCC_ABBA_1	290	295	PF00400	0.338
LIG_BRCT_BRCA1_1	34	38	PF00533	0.514
LIG_deltaCOP1_diTrp_1	244	251	PF00928	0.400
LIG_FHA_1	189	195	PF00498	0.497
LIG_FHA_1	295	301	PF00498	0.464
LIG_FHA_1	98	104	PF00498	0.373
LIG_FHA_2	197	203	PF00498	0.436
LIG_FHA_2	304	310	PF00498	0.599
LIG_FHA_2	91	97	PF00498	0.457
LIG_LIR_Gen_1	117	127	PF02991	0.400
LIG_LIR_Nem_3	117	122	PF02991	0.387
LIG_NRBOX	266	272	PF00104	0.328
LIG_PCNA_PIPBox_1	161	170	PF02747	0.385
LIG_PCNA_yPIPBox_3	61	75	PF02747	0.419
LIG_SH2_SRC	213	216	PF00017	0.330
LIG_SH2_STAT5	213	216	PF00017	0.446
LIG_SH3_3	171	177	PF00018	0.431
LIG_SUMO_SIM_anti_2	129	136	PF11976	0.573
LIG_WRC_WIRS_1	164	169	PF05994	0.433
MOD_CDK_SPK_2	14	19	PF00069	0.585
MOD_CK1_1	14	20	PF00069	0.711
MOD_CK1_1	200	206	PF00069	0.475
MOD_CK1_1	280	286	PF00069	0.545
MOD_CK1_1	32	38	PF00069	0.529
MOD_CK1_1	5	11	PF00069	0.534
MOD_CK1_1	90	96	PF00069	0.539
MOD_CK2_1	196	202	PF00069	0.444
MOD_CK2_1	303	309	PF00069	0.440
MOD_CK2_1	34	40	PF00069	0.392
MOD_GlcNHglycan	119	122	PF01048	0.441
MOD_GlcNHglycan	14	17	PF01048	0.685
MOD_GlcNHglycan	210	213	PF01048	0.437
MOD_GlcNHglycan	281	285	PF01048	0.549
MOD_GlcNHglycan	31	34	PF01048	0.570
MOD_GlcNHglycan	7	10	PF01048	0.723
MOD_GSK3_1	117	124	PF00069	0.379
MOD_GSK3_1	129	136	PF00069	0.405
MOD_GSK3_1	196	203	PF00069	0.423
MOD_GSK3_1	29	36	PF00069	0.583
MOD_N-GLC_1	5	10	PF02516	0.629
MOD_NEK2_1	2	7	PF00069	0.504
MOD_PIKK_1	260	266	PF00454	0.473
MOD_PKA_1	85	91	PF00069	0.589
MOD_PKA_2	2	8	PF00069	0.707
MOD_PKA_2	85	91	PF00069	0.592
MOD_Plk_1	294	300	PF00069	0.450
MOD_Plk_2-3	163	169	PF00069	0.446
MOD_Plk_4	108	114	PF00069	0.499
MOD_Plk_4	129	135	PF00069	0.602
MOD_Plk_4	163	169	PF00069	0.392
MOD_Plk_4	200	206	PF00069	0.429
MOD_Plk_4	34	40	PF00069	0.506
MOD_Plk_4	51	57	PF00069	0.514
MOD_ProDKin_1	133	139	PF00069	0.575
MOD_ProDKin_1	14	20	PF00069	0.704
TRG_DiLeu_BaEn_1	310	315	PF01217	0.380
TRG_DiLeu_BaEn_2	162	168	PF01217	0.382
TRG_Pf-PMV_PEXEL_1	69	73	PF00026	0.485

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBF0	Leptomonas seymouri	50%	71%
A0A1X0NPV5	Trypanosomatidae	36%	95%
A0A3R7RGL1	Trypanosoma rangeli	35%	100%
A4HTC9	Leishmania infantum	99%	100%
E9AI29	Leishmania braziliensis	79%	100%
E9ALC2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4QII3	Leishmania major	92%	100%
V5BYB8	Trypanosoma cruzi	37%	100%