RNA binding protein-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

RNA binding protein-like protein

Species:

Leishmania donovani

UniProt:

A0A3S7WQ00_LEIDO

TriTrypDb:

LdBPK_071150.1 , LdCL_070016300 , LDHU3_07.1360

Length:

334

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	1
GO:0043226	organelle	2	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A0A3S7WQ00

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WQ00

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	116	120	PF00656	0.663
CLV_C14_Caspase3-7	164	168	PF00656	0.832
CLV_C14_Caspase3-7	180	184	PF00656	0.556
CLV_C14_Caspase3-7	205	209	PF00656	0.705
CLV_C14_Caspase3-7	235	239	PF00656	0.754
CLV_C14_Caspase3-7	247	251	PF00656	0.622
CLV_NRD_NRD_1	139	141	PF00675	0.781
CLV_NRD_NRD_1	331	333	PF00675	0.513
CLV_PCSK_KEX2_1	139	141	PF00082	0.781
CLV_PCSK_KEX2_1	331	333	PF00082	0.513
CLV_PCSK_PC1ET2_1	139	141	PF00082	0.781
CLV_PCSK_SKI1_1	118	122	PF00082	0.598
DOC_MAPK_gen_1	118	127	PF00069	0.690
DOC_PP2B_LxvP_1	18	21	PF13499	0.352
DOC_PP2B_LxvP_1	64	67	PF13499	0.411
DOC_USP7_MATH_1	108	112	PF00917	0.710
DOC_USP7_MATH_1	148	152	PF00917	0.793
DOC_USP7_MATH_1	53	57	PF00917	0.511
DOC_USP7_MATH_1	82	86	PF00917	0.511
DOC_USP7_UBL2_3	122	126	PF12436	0.756
DOC_WW_Pin1_4	304	309	PF00397	0.781
DOC_WW_Pin1_4	324	329	PF00397	0.733
DOC_WW_Pin1_4	8	13	PF00397	0.407
LIG_FHA_1	147	153	PF00498	0.739
LIG_FHA_1	40	46	PF00498	0.411
LIG_FHA_1	66	72	PF00498	0.399
LIG_FHA_2	131	137	PF00498	0.766
LIG_LIR_Gen_1	4	12	PF02991	0.411
LIG_LIR_Nem_3	4	8	PF02991	0.411
LIG_PTAP_UEV_1	224	229	PF05743	0.714
LIG_REV1ctd_RIR_1	78	87	PF16727	0.411
LIG_SH2_NCK_1	52	56	PF00017	0.511
LIG_SH2_STAT3	74	77	PF00017	0.467
LIG_SH2_STAT5	44	47	PF00017	0.411
LIG_SH3_3	122	128	PF00018	0.633
LIG_SH3_3	222	228	PF00018	0.692
LIG_SH3_3	28	34	PF00018	0.340
LIG_TRAF2_1	168	171	PF00917	0.624
LIG_TRAF2_1	245	248	PF00917	0.789
LIG_TRAF2_1	256	259	PF00917	0.805
MOD_CDC14_SPxK_1	11	14	PF00782	0.399
MOD_CDK_SPxK_1	8	14	PF00069	0.399
MOD_CDK_SPxxK_3	324	331	PF00069	0.718
MOD_CK1_1	29	35	PF00069	0.411
MOD_CK1_1	294	300	PF00069	0.762
MOD_CK1_1	316	322	PF00069	0.676
MOD_CK1_1	56	62	PF00069	0.511
MOD_CK2_1	130	136	PF00069	0.755
MOD_CK2_1	148	154	PF00069	0.797
MOD_CK2_1	165	171	PF00069	0.540
MOD_CK2_1	179	185	PF00069	0.746
MOD_CK2_1	227	233	PF00069	0.726
MOD_CK2_1	242	248	PF00069	0.708
MOD_Cter_Amidation	329	332	PF01082	0.519
MOD_GlcNHglycan	110	113	PF01048	0.714
MOD_GlcNHglycan	167	170	PF01048	0.826
MOD_GlcNHglycan	171	175	PF01048	0.754
MOD_GlcNHglycan	293	296	PF01048	0.831
MOD_GlcNHglycan	302	305	PF01048	0.774
MOD_GlcNHglycan	315	318	PF01048	0.660
MOD_GlcNHglycan	45	48	PF01048	0.427
MOD_GlcNHglycan	84	87	PF01048	0.411
MOD_GSK3_1	110	117	PF00069	0.749
MOD_GSK3_1	130	137	PF00069	0.523
MOD_GSK3_1	146	153	PF00069	0.528
MOD_GSK3_1	175	182	PF00069	0.750
MOD_GSK3_1	223	230	PF00069	0.737
MOD_GSK3_1	300	307	PF00069	0.807
MOD_GSK3_1	34	41	PF00069	0.430
MOD_N-GLC_1	313	318	PF02516	0.683
MOD_NEK2_1	26	31	PF00069	0.515
MOD_NEK2_2	39	44	PF00069	0.411
MOD_NEK2_2	84	89	PF00069	0.411
MOD_PIKK_1	316	322	PF00454	0.639
MOD_PIKK_1	56	62	PF00454	0.380
MOD_PKA_2	291	297	PF00069	0.834
MOD_PKA_2	300	306	PF00069	0.694
MOD_PKA_2	34	40	PF00069	0.467
MOD_Plk_2-3	110	116	PF00069	0.699
MOD_Plk_2-3	130	136	PF00069	0.479
MOD_Plk_2-3	150	156	PF00069	0.798
MOD_Plk_2-3	175	181	PF00069	0.763
MOD_Plk_2-3	242	248	PF00069	0.719
MOD_Plk_4	26	32	PF00069	0.411
MOD_Plk_4	39	45	PF00069	0.411
MOD_ProDKin_1	304	310	PF00069	0.781
MOD_ProDKin_1	324	330	PF00069	0.733
MOD_ProDKin_1	8	14	PF00069	0.383
MOD_SUMO_rev_2	113	123	PF00179	0.596
MOD_SUMO_rev_2	46	51	PF00179	0.411
MOD_SUMO_rev_2	9	18	PF00179	0.394
TRG_NLS_Bipartite_1	121	143	PF00514	0.717

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2Y4	Leptomonas seymouri	48%	100%
A4H548	Leishmania braziliensis	64%	100%
A4HTC4	Leishmania infantum	100%	100%
E9ALB7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	72%	100%
Q4QII7	Leishmania major	82%	98%