UBA domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7WPY2_LEIDO

TriTrypDb:

LdBPK_070900.1 , LdCL_070013800 , LDHU3_07.1070

Length:

290

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WPY2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WPY2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	264	268	PF00656	0.500
CLV_NRD_NRD_1	103	105	PF00675	0.586
CLV_NRD_NRD_1	107	109	PF00675	0.567
CLV_NRD_NRD_1	185	187	PF00675	0.598
CLV_NRD_NRD_1	273	275	PF00675	0.529
CLV_PCSK_KEX2_1	102	104	PF00082	0.604
CLV_PCSK_KEX2_1	109	111	PF00082	0.568
CLV_PCSK_KEX2_1	185	187	PF00082	0.598
CLV_PCSK_KEX2_1	273	275	PF00082	0.529
CLV_PCSK_PC1ET2_1	109	111	PF00082	0.581
CLV_PCSK_SKI1_1	82	86	PF00082	0.557
DEG_Nend_UBRbox_4	1	3	PF02207	0.587
DOC_CKS1_1	157	162	PF01111	0.659
DOC_MAPK_gen_1	236	245	PF00069	0.604
DOC_PP2B_LxvP_1	68	71	PF13499	0.614
DOC_PP2B_LxvP_1	7	10	PF13499	0.621
DOC_PP4_FxxP_1	5	8	PF00568	0.648
DOC_USP7_MATH_1	223	227	PF00917	0.741
DOC_WW_Pin1_4	125	130	PF00397	0.692
DOC_WW_Pin1_4	156	161	PF00397	0.714
DOC_WW_Pin1_4	284	289	PF00397	0.628
LIG_14-3-3_CanoR_1	168	173	PF00244	0.614
LIG_14-3-3_CanoR_1	238	245	PF00244	0.555
LIG_CaM_IQ_9	178	193	PF13499	0.558
LIG_EVH1_1	5	9	PF00568	0.633
LIG_FHA_1	157	163	PF00498	0.654
LIG_FHA_1	179	185	PF00498	0.583
LIG_FHA_1	219	225	PF00498	0.646
LIG_FHA_1	43	49	PF00498	0.593
LIG_FHA_1	58	64	PF00498	0.432
LIG_FHA_2	144	150	PF00498	0.646
LIG_FHA_2	200	206	PF00498	0.587
LIG_GBD_Chelix_1	252	260	PF00786	0.515
LIG_LIR_Apic_2	3	8	PF02991	0.552
LIG_PCNA_yPIPBox_3	33	43	PF02747	0.511
LIG_SH2_SRC	278	281	PF00017	0.513
LIG_SH2_STAT5	278	281	PF00017	0.570
LIG_SH3_3	154	160	PF00018	0.736
LIG_SH3_3	3	9	PF00018	0.700
LIG_SUMO_SIM_anti_2	249	255	PF11976	0.583
LIG_TRFH_1	5	9	PF08558	0.546
MOD_CK1_1	156	162	PF00069	0.681
MOD_CK1_1	164	170	PF00069	0.658
MOD_CK1_1	209	215	PF00069	0.688
MOD_CK1_1	23	29	PF00069	0.543
MOD_CK1_1	269	275	PF00069	0.579
MOD_CK2_1	139	145	PF00069	0.740
MOD_CK2_1	199	205	PF00069	0.672
MOD_CK2_1	213	219	PF00069	0.559
MOD_CK2_1	56	62	PF00069	0.489
MOD_GlcNHglycan	133	136	PF01048	0.726
MOD_GlcNHglycan	141	144	PF01048	0.569
MOD_GlcNHglycan	216	219	PF01048	0.733
MOD_GlcNHglycan	221	224	PF01048	0.673
MOD_GlcNHglycan	245	248	PF01048	0.562
MOD_GlcNHglycan	262	266	PF01048	0.568
MOD_GSK3_1	127	134	PF00069	0.653
MOD_GSK3_1	139	146	PF00069	0.646
MOD_GSK3_1	149	156	PF00069	0.592
MOD_GSK3_1	164	171	PF00069	0.686
MOD_GSK3_1	205	212	PF00069	0.630
MOD_GSK3_1	214	221	PF00069	0.613
MOD_N-GLC_1	18	23	PF02516	0.616
MOD_NEK2_1	153	158	PF00069	0.550
MOD_NEK2_1	243	248	PF00069	0.587
MOD_NEK2_1	42	47	PF00069	0.524
MOD_NEK2_1	56	61	PF00069	0.526
MOD_PIKK_1	178	184	PF00454	0.596
MOD_PK_1	266	272	PF00069	0.497
MOD_PKA_2	272	278	PF00069	0.700
MOD_Plk_1	18	24	PF00069	0.549
MOD_Plk_1	266	272	PF00069	0.585
MOD_ProDKin_1	125	131	PF00069	0.686
MOD_ProDKin_1	156	162	PF00069	0.712
MOD_ProDKin_1	284	290	PF00069	0.637
TRG_ER_diArg_1	102	104	PF00400	0.667
TRG_ER_diArg_1	107	110	PF00400	0.585
TRG_ER_diArg_1	184	186	PF00400	0.597
TRG_ER_diArg_1	273	276	PF00400	0.538
TRG_NLS_MonoExtN_4	107	112	PF00514	0.584
TRG_Pf-PMV_PEXEL_1	195	200	PF00026	0.563
TRG_Pf-PMV_PEXEL_1	20	25	PF00026	0.605

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PDZ9	Leptomonas seymouri	39%	95%
A4H531	Leishmania braziliensis	69%	99%
A4HTA5	Leishmania infantum	99%	100%
E9AL94	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	99%
Q4QIL0	Leishmania major	89%	100%