Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

cysteine peptidase B (CPB)

Species:

Leishmania donovani

UniProt:

A0A3S7WPW5_LEIDO

TriTrypDb:

LdBPK_070600.1 , LdCL_070011000 , LDHU3_07.0750

Length:

1553

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	7
GO:0110165	cellular anatomical entity	1	7

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Expansion

Sequence features

A0A3S7WPW5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

Could not find GO biological_process term for this entry.

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Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	1
GO:0016787	hydrolase activity	2	1

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1029	1033	PF00656	0.600
CLV_C14_Caspase3-7	1085	1089	PF00656	0.753
CLV_C14_Caspase3-7	159	163	PF00656	0.594
CLV_C14_Caspase3-7	503	507	PF00656	0.722
CLV_C14_Caspase3-7	829	833	PF00656	0.605
CLV_C14_Caspase3-7	911	915	PF00656	0.641
CLV_NRD_NRD_1	1004	1006	PF00675	0.503
CLV_NRD_NRD_1	1007	1009	PF00675	0.537
CLV_NRD_NRD_1	1157	1159	PF00675	0.396
CLV_NRD_NRD_1	133	135	PF00675	0.541

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I3P6	Leptomonas seymouri	32%	81%
A4H505	Leishmania braziliensis	60%	100%
A4HT73	Leishmania infantum	99%	100%
E9AL67	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%
Q4QIN7	Leishmania major	88%	100%

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