Molybdopterin guanine dinucleotide synthesis protein B, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Molybdopterin guanine dinucleotide synthesis protein B, putative

Species:

Leishmania donovani

UniProt:

A0A3S7WPV7_LEIDO

TriTrypDb:

LdBPK_070630.1 , LdCL_070011300 , LDHU3_07.0780

Length:

1370

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

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Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	1
GO:0005730	nucleolus	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

A0A3S7WPV7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

No structure information available for this entry

Related structures:

Function

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Biological processes
Term	Name	Level	Count
GO:0000448	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	10	1
GO:0000469	cleavage involved in rRNA processing	7	1
GO:0000478	endonucleolytic cleavage involved in rRNA processing	8	1
GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	9	1
GO:0006139	nucleobase-containing compound metabolic process	3	7
GO:0006396	RNA processing	6	7
GO:0006725	cellular aromatic compound metabolic process	3	7
GO:0006807	nitrogen compound metabolic process	2	7
GO:0008152	metabolic process	1	7
GO:0009987	cellular process	1	7

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Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	7
GO:0016301	kinase activity	4	7
GO:0016740	transferase activity	2	7
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	7
GO:0016773	phosphotransferase activity, alcohol group as acceptor	4	7
GO:0019205	nucleobase-containing compound kinase activity	5	7
GO:0051731	polynucleotide 5'-hydroxyl-kinase activity	5	7

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	16	20	PF00656	0.470
CLV_C14_Caspase3-7	291	295	PF00656	0.621
CLV_C14_Caspase3-7	320	324	PF00656	0.479
CLV_C14_Caspase3-7	662	666	PF00656	0.509
CLV_NRD_NRD_1	1011	1013	PF00675	0.451
CLV_NRD_NRD_1	1223	1225	PF00675	0.522
CLV_NRD_NRD_1	244	246	PF00675	0.482
CLV_NRD_NRD_1	282	284	PF00675	0.639
CLV_NRD_NRD_1	367	369	PF00675	0.522
CLV_NRD_NRD_1	381	383	PF00675	0.635

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IIH1	Leptomonas seymouri	48%	100%
A4H508	Leishmania braziliensis	71%	99%
A4HT70	Leishmania infantum	99%	100%
E9AL70	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	99%
Q4QIN4	Leishmania major	91%	99%

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