Leucine-rich repeat-containing protein 51

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7WPS7_LEIDO

TriTrypDb:

LdBPK_070460.1 , LdCL_070008100 , LDHU3_07.0380

Length:

848

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	6
GO:0005929	cilium	4	6
GO:0005930	axoneme	2	1
GO:0042995	cell projection	2	6
GO:0043226	organelle	2	6
GO:0043227	membrane-bounded organelle	3	6
GO:0110165	cellular anatomical entity	1	7
GO:0120025	plasma membrane bounded cell projection	3	6

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Expansion

Sequence features

A0A3S7WPS7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WPS7

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	156	160	PF00656	0.750
CLV_C14_Caspase3-7	500	504	PF00656	0.719
CLV_C14_Caspase3-7	758	762	PF00656	0.566
CLV_NRD_NRD_1	10	12	PF00675	0.509
CLV_NRD_NRD_1	120	122	PF00675	0.678
CLV_NRD_NRD_1	143	145	PF00675	0.656
CLV_NRD_NRD_1	349	351	PF00675	0.539
CLV_NRD_NRD_1	417	419	PF00675	0.553
CLV_NRD_NRD_1	472	474	PF00675	0.768
CLV_NRD_NRD_1	657	659	PF00675	0.492

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I156	Leptomonas seymouri	48%	100%
A4H4X5	Leishmania braziliensis	70%	99%
A4HT48	Leishmania infantum	97%	100%
E9AL40	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	100%
Q4QIR4	Leishmania major	93%	100%

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