CLASP_N domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7WPQ1_LEIDO

TriTrypDb:

LdBPK_070050.1 , LdCL_070005400 , LDHU3_07.0080

Length:

314

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WPQ1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WPQ1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	170	174	PF00656	0.535
CLV_NRD_NRD_1	224	226	PF00675	0.643
CLV_NRD_NRD_1	241	243	PF00675	0.581
CLV_NRD_NRD_1	299	301	PF00675	0.613
CLV_PCSK_FUR_1	297	301	PF00082	0.689
CLV_PCSK_KEX2_1	239	241	PF00082	0.566
CLV_PCSK_KEX2_1	296	298	PF00082	0.595
CLV_PCSK_KEX2_1	299	301	PF00082	0.609
CLV_PCSK_KEX2_1	53	55	PF00082	0.454
CLV_PCSK_PC1ET2_1	239	241	PF00082	0.566
CLV_PCSK_PC1ET2_1	296	298	PF00082	0.595
CLV_PCSK_PC1ET2_1	53	55	PF00082	0.454
CLV_PCSK_SKI1_1	102	106	PF00082	0.498
CLV_PCSK_SKI1_1	153	157	PF00082	0.432
CLV_PCSK_SKI1_1	212	216	PF00082	0.588
CLV_PCSK_SKI1_1	226	230	PF00082	0.550
CLV_PCSK_SKI1_1	300	304	PF00082	0.697
CLV_PCSK_SKI1_1	77	81	PF00082	0.348
DEG_APCC_DBOX_1	148	156	PF00400	0.428
DEG_APCC_DBOX_1	211	219	PF00400	0.583
DEG_APCC_DBOX_1	76	84	PF00400	0.343
DEG_SPOP_SBC_1	168	172	PF00917	0.463
DOC_CKS1_1	177	182	PF01111	0.635
DOC_CYCLIN_RxL_1	74	84	PF00134	0.353
DOC_MAPK_gen_1	102	112	PF00069	0.477
DOC_MAPK_gen_1	149	157	PF00069	0.400
DOC_MAPK_gen_1	296	306	PF00069	0.607
DOC_MAPK_gen_1	53	62	PF00069	0.576
DOC_MAPK_MEF2A_6	105	114	PF00069	0.391
DOC_MAPK_MEF2A_6	297	306	PF00069	0.587
DOC_PP1_RVXF_1	130	136	PF00149	0.405
DOC_USP7_MATH_1	168	172	PF00917	0.710
DOC_WW_Pin1_4	119	124	PF00397	0.390
DOC_WW_Pin1_4	176	181	PF00397	0.635
DOC_WW_Pin1_4	200	205	PF00397	0.602
DOC_WW_Pin1_4	270	275	PF00397	0.678
DOC_WW_Pin1_4	290	295	PF00397	0.514
DOC_WW_Pin1_4	306	311	PF00397	0.689
DOC_WW_Pin1_4	4	9	PF00397	0.504
LIG_14-3-3_CanoR_1	118	122	PF00244	0.364
LIG_14-3-3_CanoR_1	169	177	PF00244	0.605
LIG_14-3-3_CanoR_1	225	235	PF00244	0.627
LIG_14-3-3_CanoR_1	299	305	PF00244	0.599
LIG_Actin_WH2_2	103	120	PF00022	0.473
LIG_BIR_II_1	1	5	PF00653	0.478
LIG_FHA_1	120	126	PF00498	0.380
LIG_FHA_1	21	27	PF00498	0.499
LIG_FHA_1	227	233	PF00498	0.571
LIG_FHA_1	275	281	PF00498	0.616
LIG_FHA_1	301	307	PF00498	0.696
LIG_FHA_1	56	62	PF00498	0.560
LIG_FHA_1	73	79	PF00498	0.433
LIG_FHA_1	99	105	PF00498	0.360
LIG_FHA_2	142	148	PF00498	0.506
LIG_FHA_2	253	259	PF00498	0.617
LIG_FHA_2	273	279	PF00498	0.640
LIG_FHA_2	83	89	PF00498	0.343
LIG_NRBOX	85	91	PF00104	0.432
LIG_SH2_STAT5	235	238	PF00017	0.532
LIG_SH3_2	307	312	PF14604	0.615
LIG_SH3_3	174	180	PF00018	0.739
LIG_SH3_3	202	208	PF00018	0.612
LIG_SH3_3	268	274	PF00018	0.803
LIG_SH3_3	301	307	PF00018	0.625
LIG_SH3_CIN85_PxpxPR_1	180	185	PF14604	0.555
LIG_SUMO_SIM_par_1	287	293	PF11976	0.610
LIG_SxIP_EBH_1	225	238	PF03271	0.625
LIG_UBA3_1	288	296	PF00899	0.573
MOD_CDC14_SPxK_1	293	296	PF00782	0.577
MOD_CDC14_SPxK_1	309	312	PF00782	0.619
MOD_CDK_SPxK_1	290	296	PF00069	0.574
MOD_CDK_SPxK_1	306	312	PF00069	0.614
MOD_CDK_SPxxK_3	178	185	PF00069	0.552
MOD_CDK_SPxxK_3	290	297	PF00069	0.577
MOD_CK1_1	141	147	PF00069	0.612
MOD_CK1_1	251	257	PF00069	0.766
MOD_CK1_1	68	74	PF00069	0.636
MOD_CK2_1	133	139	PF00069	0.422
MOD_CK2_1	141	147	PF00069	0.444
MOD_CK2_1	190	196	PF00069	0.598
MOD_CK2_1	252	258	PF00069	0.562
MOD_CK2_1	82	88	PF00069	0.343
MOD_GlcNHglycan	139	143	PF01048	0.568
MOD_GlcNHglycan	229	232	PF01048	0.582
MOD_GlcNHglycan	27	30	PF01048	0.395
MOD_GlcNHglycan	65	68	PF01048	0.648
MOD_GlcNHglycan	91	94	PF01048	0.367
MOD_GSK3_1	117	124	PF00069	0.481
MOD_GSK3_1	196	203	PF00069	0.728
MOD_GSK3_1	227	234	PF00069	0.556
MOD_GSK3_1	248	255	PF00069	0.646
MOD_GSK3_1	270	277	PF00069	0.639
MOD_GSK3_1	65	72	PF00069	0.605
MOD_N-GLC_1	300	305	PF02516	0.646
MOD_NEK2_1	116	121	PF00069	0.392
MOD_NEK2_1	138	143	PF00069	0.544
MOD_NEK2_1	167	172	PF00069	0.528
MOD_NEK2_1	89	94	PF00069	0.392
MOD_PIKK_1	55	61	PF00454	0.442
MOD_PKA_1	197	203	PF00069	0.552
MOD_PKA_2	117	123	PF00069	0.478
MOD_PKA_2	168	174	PF00069	0.672
MOD_PKA_2	248	254	PF00069	0.536
MOD_PKA_2	55	61	PF00069	0.468
MOD_PKB_1	240	248	PF00069	0.590
MOD_PKB_1	298	306	PF00069	0.670
MOD_Plk_1	216	222	PF00069	0.544
MOD_Plk_1	243	249	PF00069	0.598
MOD_Plk_1	300	306	PF00069	0.697
MOD_Plk_2-3	22	28	PF00069	0.476
MOD_Plk_4	121	127	PF00069	0.460
MOD_Plk_4	231	237	PF00069	0.529
MOD_ProDKin_1	119	125	PF00069	0.388
MOD_ProDKin_1	176	182	PF00069	0.636
MOD_ProDKin_1	200	206	PF00069	0.602
MOD_ProDKin_1	270	276	PF00069	0.680
MOD_ProDKin_1	290	296	PF00069	0.517
MOD_ProDKin_1	306	312	PF00069	0.693
MOD_ProDKin_1	4	10	PF00069	0.504
MOD_SUMO_rev_2	193	200	PF00179	0.691
TRG_DiLeu_BaEn_1	57	62	PF01217	0.495
TRG_DiLeu_BaLyEn_6	74	79	PF01217	0.372
TRG_ER_diArg_1	240	242	PF00400	0.572
TRG_ER_diArg_1	297	300	PF00400	0.602
TRG_NLS_Bipartite_1	225	243	PF00514	0.633
TRG_NLS_MonoCore_2	238	243	PF00514	0.651
TRG_NLS_MonoCore_2	295	300	PF00514	0.585
TRG_NLS_MonoExtC_3	238	244	PF00514	0.652
TRG_NLS_MonoExtC_3	295	300	PF00514	0.595
TRG_NLS_MonoExtN_4	294	300	PF00514	0.594
TRG_Pf-PMV_PEXEL_1	287	292	PF00026	0.606
TRG_Pf-PMV_PEXEL_1	300	305	PF00026	0.536
TRG_Pf-PMV_PEXEL_1	77	81	PF00026	0.348

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HZD5	Leptomonas seymouri	40%	100%
A4H4U7	Leishmania braziliensis	73%	100%
A4HT26	Leishmania infantum	100%	100%
E9AL14	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%
Q4QIU0	Leishmania major	90%	100%