Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3S7WPP9_LEIDO

TriTrypDb:

LdBPK_061270.1 , LdCL_060017900 , LDHU3_06.1420

Length:

791

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WPP9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WPP9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	15	19	PF00656	0.564
CLV_C14_Caspase3-7	83	87	PF00656	0.467
CLV_MEL_PAP_1	530	536	PF00089	0.625
CLV_NRD_NRD_1	256	258	PF00675	0.498
CLV_NRD_NRD_1	307	309	PF00675	0.708
CLV_NRD_NRD_1	381	383	PF00675	0.739
CLV_NRD_NRD_1	43	45	PF00675	0.659
CLV_NRD_NRD_1	443	445	PF00675	0.720
CLV_NRD_NRD_1	486	488	PF00675	0.551
CLV_NRD_NRD_1	510	512	PF00675	0.624
CLV_NRD_NRD_1	577	579	PF00675	0.704
CLV_NRD_NRD_1	602	604	PF00675	0.677
CLV_NRD_NRD_1	645	647	PF00675	0.737
CLV_NRD_NRD_1	669	671	PF00675	0.658
CLV_NRD_NRD_1	738	740	PF00675	0.655
CLV_NRD_NRD_1	751	753	PF00675	0.677
CLV_NRD_NRD_1	9	11	PF00675	0.607
CLV_PCSK_KEX2_1	142	144	PF00082	0.624
CLV_PCSK_KEX2_1	256	258	PF00082	0.636
CLV_PCSK_KEX2_1	389	391	PF00082	0.636
CLV_PCSK_KEX2_1	43	45	PF00082	0.659
CLV_PCSK_KEX2_1	443	445	PF00082	0.720
CLV_PCSK_KEX2_1	510	512	PF00082	0.624
CLV_PCSK_KEX2_1	579	581	PF00082	0.740
CLV_PCSK_KEX2_1	602	604	PF00082	0.677
CLV_PCSK_KEX2_1	644	646	PF00082	0.737
CLV_PCSK_KEX2_1	669	671	PF00082	0.662
CLV_PCSK_KEX2_1	751	753	PF00082	0.748
CLV_PCSK_KEX2_1	9	11	PF00082	0.607
CLV_PCSK_KEX2_1	92	94	PF00082	0.610
CLV_PCSK_PC1ET2_1	142	144	PF00082	0.624
CLV_PCSK_PC1ET2_1	389	391	PF00082	0.627
CLV_PCSK_PC1ET2_1	579	581	PF00082	0.628
CLV_PCSK_PC1ET2_1	92	94	PF00082	0.610
CLV_PCSK_PC7_1	138	144	PF00082	0.617
CLV_PCSK_SKI1_1	165	169	PF00082	0.613
CLV_PCSK_SKI1_1	2	6	PF00082	0.637
CLV_PCSK_SKI1_1	366	370	PF00082	0.664
CLV_PCSK_SKI1_1	394	398	PF00082	0.766
CLV_PCSK_SKI1_1	476	480	PF00082	0.678
CLV_PCSK_SKI1_1	493	497	PF00082	0.632
CLV_PCSK_SKI1_1	602	606	PF00082	0.726
CLV_PCSK_SKI1_1	66	70	PF00082	0.610
CLV_PCSK_SKI1_1	778	782	PF00082	0.728
CLV_PCSK_SKI1_1	786	790	PF00082	0.652
DEG_APCC_DBOX_1	325	333	PF00400	0.707
DEG_APCC_DBOX_1	365	373	PF00400	0.662
DEG_APCC_DBOX_1	428	436	PF00400	0.631
DEG_Nend_UBRbox_1	1	4	PF02207	0.652
DEG_SCF_FBW7_1	564	571	PF00400	0.706
DEG_SPOP_SBC_1	114	118	PF00917	0.573
DEG_SPOP_SBC_1	403	407	PF00917	0.672
DEG_SPOP_SBC_1	568	572	PF00917	0.804
DOC_ANK_TNKS_1	496	503	PF00023	0.669
DOC_CKS1_1	565	570	PF01111	0.707
DOC_CKS1_1	604	609	PF01111	0.677
DOC_CYCLIN_RxL_1	363	370	PF00134	0.664
DOC_CYCLIN_RxL_1	734	748	PF00134	0.540
DOC_MAPK_DCC_7	778	787	PF00069	0.717
DOC_MAPK_gen_1	256	262	PF00069	0.595
DOC_MAPK_gen_1	280	287	PF00069	0.721
DOC_MAPK_gen_1	470	479	PF00069	0.631
DOC_MAPK_gen_1	602	610	PF00069	0.687
DOC_MAPK_gen_1	736	744	PF00069	0.679
DOC_MAPK_gen_1	778	787	PF00069	0.668
DOC_MAPK_MEF2A_6	237	246	PF00069	0.481
DOC_MAPK_MEF2A_6	781	789	PF00069	0.660
DOC_MAPK_RevD_3	367	383	PF00069	0.553
DOC_PP1_RVXF_1	738	745	PF00149	0.546
DOC_PP1_RVXF_1	784	790	PF00149	0.690
DOC_PP4_FxxP_1	534	537	PF00568	0.783
DOC_PP4_FxxP_1	561	564	PF00568	0.663
DOC_USP7_MATH_1	147	151	PF00917	0.654
DOC_USP7_MATH_1	192	196	PF00917	0.584
DOC_USP7_MATH_1	223	227	PF00917	0.513
DOC_USP7_MATH_1	456	460	PF00917	0.566
DOC_USP7_MATH_1	478	482	PF00917	0.762
DOC_USP7_MATH_1	501	505	PF00917	0.767
DOC_USP7_MATH_1	682	686	PF00917	0.747
DOC_USP7_UBL2_3	736	740	PF12436	0.709
DOC_WW_Pin1_4	115	120	PF00397	0.657
DOC_WW_Pin1_4	133	138	PF00397	0.783
DOC_WW_Pin1_4	17	22	PF00397	0.681
DOC_WW_Pin1_4	297	302	PF00397	0.752
DOC_WW_Pin1_4	409	414	PF00397	0.816
DOC_WW_Pin1_4	532	537	PF00397	0.678
DOC_WW_Pin1_4	560	565	PF00397	0.770
DOC_WW_Pin1_4	569	574	PF00397	0.838
DOC_WW_Pin1_4	586	591	PF00397	0.673
DOC_WW_Pin1_4	594	599	PF00397	0.732
DOC_WW_Pin1_4	603	608	PF00397	0.469
DOC_WW_Pin1_4	612	617	PF00397	0.704
DOC_WW_Pin1_4	656	661	PF00397	0.731
DOC_WW_Pin1_4	691	696	PF00397	0.706
DOC_WW_Pin1_4	771	776	PF00397	0.719
LIG_14-3-3_CanoR_1	209	218	PF00244	0.510
LIG_14-3-3_CanoR_1	229	236	PF00244	0.521
LIG_14-3-3_CanoR_1	256	261	PF00244	0.501
LIG_14-3-3_CanoR_1	326	330	PF00244	0.712
LIG_14-3-3_CanoR_1	35	41	PF00244	0.705
LIG_14-3-3_CanoR_1	43	51	PF00244	0.636
LIG_14-3-3_CanoR_1	457	463	PF00244	0.695
LIG_14-3-3_CanoR_1	550	558	PF00244	0.733
LIG_14-3-3_CanoR_1	580	586	PF00244	0.769
LIG_14-3-3_CanoR_1	602	607	PF00244	0.695
LIG_14-3-3_CanoR_1	624	629	PF00244	0.764
LIG_14-3-3_CanoR_1	635	642	PF00244	0.723
LIG_14-3-3_CanoR_1	669	678	PF00244	0.632
LIG_14-3-3_CanoR_1	681	690	PF00244	0.653
LIG_14-3-3_CanoR_1	739	745	PF00244	0.685
LIG_AP2alpha_2	355	357	PF02296	0.568
LIG_APCC_ABBA_1	180	185	PF00400	0.590
LIG_BIR_III_2	18	22	PF00653	0.641
LIG_BRCT_BRCA1_1	448	452	PF00533	0.688
LIG_BRCT_BRCA1_1	596	600	PF00533	0.682
LIG_BRCT_BRCA1_1	86	90	PF00533	0.557
LIG_BRCT_BRCA1_2	86	92	PF00533	0.556
LIG_Clathr_ClatBox_1	181	185	PF01394	0.503
LIG_FHA_1	176	182	PF00498	0.450
LIG_FHA_1	20	26	PF00498	0.803
LIG_FHA_1	599	605	PF00498	0.762
LIG_FHA_1	674	680	PF00498	0.634
LIG_FHA_2	152	158	PF00498	0.637
LIG_FHA_2	18	24	PF00498	0.653
LIG_FHA_2	185	191	PF00498	0.550
LIG_FHA_2	211	217	PF00498	0.636
LIG_FHA_2	259	265	PF00498	0.473
LIG_FHA_2	35	41	PF00498	0.485
LIG_FHA_2	81	87	PF00498	0.468
LIG_GBD_Chelix_1	160	168	PF00786	0.585
LIG_LIR_Apic_2	559	564	PF02991	0.660
LIG_LIR_Gen_1	154	164	PF02991	0.498
LIG_LIR_Gen_1	259	270	PF02991	0.544
LIG_LIR_Gen_1	312	319	PF02991	0.644
LIG_LIR_Gen_1	355	363	PF02991	0.518
LIG_LIR_Gen_1	556	565	PF02991	0.656
LIG_LIR_Nem_3	154	159	PF02991	0.493
LIG_LIR_Nem_3	259	265	PF02991	0.516
LIG_LIR_Nem_3	312	318	PF02991	0.621
LIG_LIR_Nem_3	342	347	PF02991	0.655
LIG_LIR_Nem_3	355	360	PF02991	0.467
LIG_LIR_Nem_3	449	455	PF02991	0.692
LIG_LIR_Nem_3	556	561	PF02991	0.652
LIG_LIR_Nem_3	701	707	PF02991	0.640
LIG_LYPXL_S_1	703	707	PF13949	0.630
LIG_LYPXL_yS_3	704	707	PF13949	0.629
LIG_MLH1_MIPbox_1	596	600	PF16413	0.682
LIG_NRBOX	163	169	PF00104	0.600
LIG_PCNA_PIPBox_1	697	706	PF02747	0.539
LIG_REV1ctd_RIR_1	607	615	PF16727	0.648
LIG_SH2_CRK	156	160	PF00017	0.581
LIG_SH2_STAP1	156	160	PF00017	0.479
LIG_SH2_STAT3	50	53	PF00017	0.569
LIG_SH2_STAT5	334	337	PF00017	0.732
LIG_SH2_STAT5	434	437	PF00017	0.792
LIG_SH2_STAT5	50	53	PF00017	0.607
LIG_SH2_STAT5	599	602	PF00017	0.588
LIG_SH2_STAT5	665	668	PF00017	0.601
LIG_SH3_1	76	82	PF00018	0.686
LIG_SH3_1	776	782	PF00018	0.690
LIG_SH3_2	410	415	PF14604	0.770
LIG_SH3_3	194	200	PF00018	0.635
LIG_SH3_3	233	239	PF00018	0.573
LIG_SH3_3	393	399	PF00018	0.750
LIG_SH3_3	407	413	PF00018	0.557
LIG_SH3_3	516	522	PF00018	0.776
LIG_SH3_3	584	590	PF00018	0.704
LIG_SH3_3	747	753	PF00018	0.626
LIG_SH3_3	76	82	PF00018	0.593
LIG_SH3_3	766	772	PF00018	0.570
LIG_SH3_3	776	782	PF00018	0.602
LIG_SUMO_SIM_anti_2	358	364	PF11976	0.520
LIG_TRAF2_1	275	278	PF00917	0.652
LIG_TRAF2_2	616	621	PF00917	0.713
LIG_WRC_WIRS_1	85	90	PF05994	0.570
LIG_WW_3	440	444	PF00397	0.728
LIG_WW_3	530	534	PF00397	0.765
MOD_CDC14_SPxK_1	412	415	PF00782	0.772
MOD_CDC14_SPxK_1	563	566	PF00782	0.666
MOD_CDK_SPK_2	133	138	PF00069	0.640
MOD_CDK_SPK_2	691	696	PF00069	0.640
MOD_CDK_SPK_2	771	776	PF00069	0.719
MOD_CDK_SPxK_1	409	415	PF00069	0.821
MOD_CDK_SPxK_1	560	566	PF00069	0.664
MOD_CDK_SPxxK_3	771	778	PF00069	0.714
MOD_CK1_1	123	129	PF00069	0.698
MOD_CK1_1	13	19	PF00069	0.817
MOD_CK1_1	136	142	PF00069	0.517
MOD_CK1_1	325	331	PF00069	0.706
MOD_CK1_1	34	40	PF00069	0.598
MOD_CK1_1	549	555	PF00069	0.717
MOD_CK1_1	559	565	PF00069	0.677
MOD_CK1_1	627	633	PF00069	0.848
MOD_CK1_1	649	655	PF00069	0.724
MOD_CK1_1	659	665	PF00069	0.739
MOD_CK1_1	689	695	PF00069	0.702
MOD_CK1_1	94	100	PF00069	0.606
MOD_CK2_1	149	155	PF00069	0.649
MOD_CK2_1	190	196	PF00069	0.474
MOD_CK2_1	228	234	PF00069	0.643
MOD_CK2_1	34	40	PF00069	0.565
MOD_CK2_1	477	483	PF00069	0.765
MOD_CK2_1	517	523	PF00069	0.752
MOD_CK2_1	669	675	PF00069	0.645
MOD_CK2_1	726	732	PF00069	0.657
MOD_GlcNHglycan	101	104	PF01048	0.665
MOD_GlcNHglycan	149	152	PF01048	0.590
MOD_GlcNHglycan	168	171	PF01048	0.572
MOD_GlcNHglycan	204	207	PF01048	0.573
MOD_GlcNHglycan	230	233	PF01048	0.565
MOD_GlcNHglycan	271	274	PF01048	0.713
MOD_GlcNHglycan	46	49	PF01048	0.655
MOD_GlcNHglycan	480	483	PF01048	0.619
MOD_GlcNHglycan	648	651	PF01048	0.797
MOD_GlcNHglycan	666	669	PF01048	0.664
MOD_GlcNHglycan	671	674	PF01048	0.671
MOD_GSK3_1	10	17	PF00069	0.795
MOD_GSK3_1	115	122	PF00069	0.747
MOD_GSK3_1	124	131	PF00069	0.625
MOD_GSK3_1	132	139	PF00069	0.666
MOD_GSK3_1	147	154	PF00069	0.684
MOD_GSK3_1	171	178	PF00069	0.513
MOD_GSK3_1	224	231	PF00069	0.527
MOD_GSK3_1	31	38	PF00069	0.638
MOD_GSK3_1	314	321	PF00069	0.623
MOD_GSK3_1	397	404	PF00069	0.720
MOD_GSK3_1	546	553	PF00069	0.786
MOD_GSK3_1	556	563	PF00069	0.654
MOD_GSK3_1	564	571	PF00069	0.709
MOD_GSK3_1	581	588	PF00069	0.759
MOD_GSK3_1	594	601	PF00069	0.629
MOD_GSK3_1	659	666	PF00069	0.786
MOD_GSK3_1	669	676	PF00069	0.737
MOD_GSK3_1	682	689	PF00069	0.588
MOD_GSK3_1	756	763	PF00069	0.735
MOD_GSK3_1	80	87	PF00069	0.563
MOD_LATS_1	99	105	PF00433	0.599
MOD_N-GLC_1	11	16	PF02516	0.744
MOD_N-GLC_1	44	49	PF02516	0.732
MOD_N-GLC_2	352	354	PF02516	0.603
MOD_NEK2_1	120	125	PF00069	0.705
MOD_NEK2_1	128	133	PF00069	0.653
MOD_NEK2_1	168	173	PF00069	0.478
MOD_NEK2_1	3	8	PF00069	0.642
MOD_NEK2_1	318	323	PF00069	0.624
MOD_NEK2_1	726	731	PF00069	0.760
MOD_NEK2_2	224	229	PF00069	0.592
MOD_NEK2_2	573	578	PF00069	0.725
MOD_PIKK_1	59	65	PF00454	0.617
MOD_PIKK_1	760	766	PF00454	0.749
MOD_PK_1	624	630	PF00069	0.676
MOD_PK_1	746	752	PF00069	0.646
MOD_PKA_1	142	148	PF00069	0.618
MOD_PKA_1	256	262	PF00069	0.457
MOD_PKA_1	382	388	PF00069	0.714
MOD_PKA_1	602	608	PF00069	0.682
MOD_PKA_1	669	675	PF00069	0.623
MOD_PKA_1	751	757	PF00069	0.721
MOD_PKA_2	142	148	PF00069	0.724
MOD_PKA_2	228	234	PF00069	0.507
MOD_PKA_2	256	262	PF00069	0.457
MOD_PKA_2	325	331	PF00069	0.706
MOD_PKA_2	34	40	PF00069	0.565
MOD_PKA_2	416	422	PF00069	0.796
MOD_PKA_2	436	442	PF00069	0.496
MOD_PKA_2	456	462	PF00069	0.564
MOD_PKA_2	517	523	PF00069	0.668
MOD_PKA_2	549	555	PF00069	0.735
MOD_PKA_2	556	562	PF00069	0.663
MOD_PKA_2	602	608	PF00069	0.674
MOD_PKA_2	669	675	PF00069	0.623
MOD_PKA_2	738	744	PF00069	0.684
MOD_PKA_2	751	757	PF00069	0.557
MOD_PKA_2	94	100	PF00069	0.690
MOD_PKB_1	644	652	PF00069	0.681
MOD_Plk_1	224	230	PF00069	0.608
MOD_Plk_1	446	452	PF00069	0.727
MOD_Plk_4	155	161	PF00069	0.482
MOD_Plk_4	258	264	PF00069	0.523
MOD_Plk_4	3	9	PF00069	0.625
MOD_Plk_4	314	320	PF00069	0.632
MOD_Plk_4	325	331	PF00069	0.706
MOD_Plk_4	358	364	PF00069	0.724
MOD_Plk_4	446	452	PF00069	0.765
MOD_Plk_4	46	52	PF00069	0.574
MOD_Plk_4	581	587	PF00069	0.741
MOD_Plk_4	716	722	PF00069	0.511
MOD_Plk_4	751	757	PF00069	0.721
MOD_Plk_4	84	90	PF00069	0.593
MOD_ProDKin_1	115	121	PF00069	0.657
MOD_ProDKin_1	133	139	PF00069	0.783
MOD_ProDKin_1	17	23	PF00069	0.679
MOD_ProDKin_1	297	303	PF00069	0.754
MOD_ProDKin_1	409	415	PF00069	0.821
MOD_ProDKin_1	532	538	PF00069	0.675
MOD_ProDKin_1	560	566	PF00069	0.772
MOD_ProDKin_1	569	575	PF00069	0.837
MOD_ProDKin_1	586	592	PF00069	0.674
MOD_ProDKin_1	594	600	PF00069	0.731
MOD_ProDKin_1	603	609	PF00069	0.471
MOD_ProDKin_1	612	618	PF00069	0.705
MOD_ProDKin_1	656	662	PF00069	0.731
MOD_ProDKin_1	691	697	PF00069	0.703
MOD_ProDKin_1	771	777	PF00069	0.718
TRG_DiLeu_BaEn_1	155	160	PF01217	0.509
TRG_DiLeu_BaEn_1	716	721	PF01217	0.722
TRG_DiLeu_BaEn_4	276	282	PF01217	0.532
TRG_DiLeu_BaLyEn_6	116	121	PF01217	0.783
TRG_ENDOCYTIC_2	156	159	PF00928	0.482
TRG_ENDOCYTIC_2	704	707	PF00928	0.629
TRG_ER_diArg_1	279	282	PF00400	0.734
TRG_ER_diArg_1	363	366	PF00400	0.621
TRG_ER_diArg_1	422	425	PF00400	0.724
TRG_ER_diArg_1	429	432	PF00400	0.732
TRG_ER_diArg_1	442	444	PF00400	0.723
TRG_ER_diArg_1	509	511	PF00400	0.635
TRG_ER_diArg_1	577	580	PF00400	0.842
TRG_ER_diArg_1	602	604	PF00400	0.677
TRG_ER_diArg_1	644	646	PF00400	0.714
TRG_ER_diArg_1	669	671	PF00400	0.668
TRG_ER_diArg_1	727	730	PF00400	0.683
TRG_ER_diArg_1	750	752	PF00400	0.738
TRG_ER_diArg_1	8	10	PF00400	0.558
TRG_ER_diArg_1	93	96	PF00400	0.649
TRG_ER_FFAT_2	559	567	PF00635	0.663
TRG_NES_CRM1_1	701	716	PF08389	0.724
TRG_Pf-PMV_PEXEL_1	290	295	PF00026	0.750
TRG_Pf-PMV_PEXEL_1	366	370	PF00026	0.618
TRG_Pf-PMV_PEXEL_1	487	491	PF00026	0.626

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HWN9	Leptomonas seymouri	34%	100%
A4H4T4	Leishmania braziliensis	57%	95%
A4HT13	Leishmania infantum	100%	100%
E9AL01	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%
Q4QIV4	Leishmania major	85%	100%