NTF2-related export protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

mRNA transport regulator MTR2, putative

Species:

Leishmania donovani

UniProt:

A0A3S7WPM6_LEIDO

TriTrypDb:

LdBPK_061210.1 , LdCL_060017200 , LDHU3_06.1360

Length:

135

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Show entries

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	1
GO:0032991	protein-containing complex	1	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0044613	nuclear pore central transport channel	3	1
GO:0110165	cellular anatomical entity	1	1
GO:0140513	nuclear protein-containing complex	2	1

Previous1Next

Expansion

Sequence features

A0A3S7WPM6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WPM6

Function

Show entries

Biological processes
Term	Name	Level	Count
GO:0006405	RNA export from nucleus	5	1
GO:0006406	mRNA export from nucleus	6	1
GO:0006810	transport	3	11
GO:0006913	nucleocytoplasmic transport	5	11
GO:0009987	cellular process	1	11
GO:0015931	nucleobase-containing compound transport	5	1
GO:0046907	intracellular transport	3	11
GO:0050657	nucleic acid transport	6	1
GO:0050658	RNA transport	4	1
GO:0051028	mRNA transport	5	1

Previous1 2Next

Could not find GO molecular_function term for this entry.

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	73	77	PF00656	0.247
CLV_C14_Caspase3-7	82	86	PF00656	0.247
CLV_NRD_NRD_1	104	106	PF00675	0.273
CLV_NRD_NRD_1	114	116	PF00675	0.229
CLV_PCSK_KEX2_1	104	106	PF00082	0.247
CLV_PCSK_KEX2_1	114	116	PF00082	0.267
CLV_PCSK_PC7_1	110	116	PF00082	0.379
CLV_PCSK_SKI1_1	11	15	PF00082	0.265
DEG_Nend_UBRbox_2	1	3	PF02207	0.632
DOC_PP1_RVXF_1	10	17	PF00149	0.265

Previous1 2 3 4Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PCC6	Leptomonas seymouri	89%	100%
A0A0S4J9D4	Bodo saltans	52%	97%
A0A1X0NHB6	Trypanosomatidae	61%	100%
A0A3R7KHF2	Trypanosoma rangeli	63%	100%
A4H4S8	Leishmania braziliensis	96%	100%
A4HT08	Leishmania infantum	100%	100%
C9ZTP1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	60%	100%
E9AKZ6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%
Q2KIW0	Bos taurus	28%	96%
Q4QIV9	Leishmania major	99%	100%

Previous1 2Next