Basic immunoglobulin-like variable motif-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania donovani

UniProt:

A0A3S7WPG2_LEIDO

TriTrypDb:

LdCL_060010700 , LDHU3_06.0660

Length:

869

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WPG2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WPG2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	176	180	PF00656	0.672
CLV_C14_Caspase3-7	31	35	PF00656	0.615
CLV_C14_Caspase3-7	620	624	PF00656	0.586
CLV_C14_Caspase3-7	629	633	PF00656	0.582
CLV_C14_Caspase3-7	759	763	PF00656	0.572
CLV_NRD_NRD_1	225	227	PF00675	0.639
CLV_NRD_NRD_1	502	504	PF00675	0.491
CLV_NRD_NRD_1	531	533	PF00675	0.562
CLV_PCSK_KEX2_1	531	533	PF00082	0.601
CLV_PCSK_SKI1_1	226	230	PF00082	0.623
CLV_PCSK_SKI1_1	301	305	PF00082	0.507
CLV_PCSK_SKI1_1	319	323	PF00082	0.348
CLV_PCSK_SKI1_1	439	443	PF00082	0.440
CLV_PCSK_SKI1_1	681	685	PF00082	0.643
DEG_Nend_UBRbox_3	1	3	PF02207	0.584
DEG_SCF_FBW7_1	105	112	PF00400	0.631
DEG_SPOP_SBC_1	635	639	PF00917	0.602
DEG_SPOP_SBC_1	771	775	PF00917	0.726
DOC_CYCLIN_RxL_1	231	245	PF00134	0.473
DOC_CYCLIN_RxL_1	848	859	PF00134	0.633
DOC_CYCLIN_yCln2_LP_2	665	671	PF00134	0.723
DOC_MAPK_HePTP_8	699	711	PF00069	0.561
DOC_MAPK_MEF2A_6	702	711	PF00069	0.559
DOC_PP2B_LxvP_1	322	325	PF13499	0.477
DOC_PP2B_LxvP_1	745	748	PF13499	0.529
DOC_PP2B_LxvP_1	853	856	PF13499	0.573
DOC_PP2B_LxvP_1	86	89	PF13499	0.615
DOC_PP4_FxxP_1	377	380	PF00568	0.506
DOC_PP4_FxxP_1	473	476	PF00568	0.518
DOC_PP4_FxxP_1	688	691	PF00568	0.648
DOC_USP7_MATH_1	109	113	PF00917	0.777
DOC_USP7_MATH_1	120	124	PF00917	0.623
DOC_USP7_MATH_1	157	161	PF00917	0.636
DOC_USP7_MATH_1	175	179	PF00917	0.671
DOC_USP7_MATH_1	23	27	PF00917	0.621
DOC_USP7_MATH_1	283	287	PF00917	0.608
DOC_USP7_MATH_1	418	422	PF00917	0.515
DOC_USP7_MATH_1	598	602	PF00917	0.615
DOC_USP7_MATH_1	634	638	PF00917	0.671
DOC_USP7_MATH_1	652	656	PF00917	0.702
DOC_USP7_MATH_1	676	680	PF00917	0.710
DOC_USP7_MATH_1	689	693	PF00917	0.553
DOC_USP7_MATH_1	733	737	PF00917	0.683
DOC_USP7_MATH_1	753	757	PF00917	0.691
DOC_USP7_MATH_1	760	764	PF00917	0.519
DOC_USP7_MATH_1	771	775	PF00917	0.619
DOC_USP7_MATH_1	797	801	PF00917	0.793
DOC_USP7_MATH_1	806	810	PF00917	0.658
DOC_USP7_MATH_1	849	853	PF00917	0.635
DOC_USP7_UBL2_3	227	231	PF12436	0.621
DOC_USP7_UBL2_3	536	540	PF12436	0.685
DOC_WW_Pin1_4	105	110	PF00397	0.551
DOC_WW_Pin1_4	193	198	PF00397	0.639
DOC_WW_Pin1_4	281	286	PF00397	0.635
DOC_WW_Pin1_4	51	56	PF00397	0.648
DOC_WW_Pin1_4	513	518	PF00397	0.514
DOC_WW_Pin1_4	588	593	PF00397	0.658
DOC_WW_Pin1_4	650	655	PF00397	0.719
DOC_WW_Pin1_4	658	663	PF00397	0.663
DOC_WW_Pin1_4	670	675	PF00397	0.662
DOC_WW_Pin1_4	728	733	PF00397	0.722
DOC_WW_Pin1_4	765	770	PF00397	0.696
DOC_WW_Pin1_4	772	777	PF00397	0.779
DOC_WW_Pin1_4	793	798	PF00397	0.697
DOC_WW_Pin1_4	802	807	PF00397	0.704
DOC_WW_Pin1_4	92	97	PF00397	0.623
LIG_14-3-3_CanoR_1	110	119	PF00244	0.678
LIG_14-3-3_CanoR_1	161	169	PF00244	0.621
LIG_14-3-3_CanoR_1	363	372	PF00244	0.573
LIG_14-3-3_CanoR_1	503	512	PF00244	0.456
LIG_14-3-3_CanoR_1	636	646	PF00244	0.666
LIG_14-3-3_CanoR_1	735	740	PF00244	0.642
LIG_14-3-3_CanoR_1	851	856	PF00244	0.713
LIG_APCC_ABBA_1	827	832	PF00400	0.481
LIG_BIR_III_2	154	158	PF00653	0.648
LIG_BIR_III_4	743	747	PF00653	0.609
LIG_BRCT_BRCA1_1	111	115	PF00533	0.615
LIG_BRCT_BRCA1_1	515	519	PF00533	0.523
LIG_BRCT_BRCA1_1	67	71	PF00533	0.540
LIG_deltaCOP1_diTrp_1	383	389	PF00928	0.514
LIG_FHA_1	100	106	PF00498	0.685
LIG_FHA_1	111	117	PF00498	0.624
LIG_FHA_1	138	144	PF00498	0.587
LIG_FHA_1	273	279	PF00498	0.616
LIG_FHA_1	294	300	PF00498	0.565
LIG_FHA_1	38	44	PF00498	0.606
LIG_FHA_1	422	428	PF00498	0.533
LIG_FHA_1	430	436	PF00498	0.479
LIG_FHA_1	469	475	PF00498	0.603
LIG_FHA_1	484	490	PF00498	0.383
LIG_FHA_1	651	657	PF00498	0.733
LIG_FHA_1	678	684	PF00498	0.668
LIG_FHA_1	756	762	PF00498	0.591
LIG_FHA_2	227	233	PF00498	0.614
LIG_FHA_2	310	316	PF00498	0.516
LIG_FHA_2	4	10	PF00498	0.585
LIG_FHA_2	636	642	PF00498	0.713
LIG_LIR_Apic_2	471	476	PF02991	0.510
LIG_LIR_Apic_2	687	691	PF02991	0.650
LIG_LIR_Gen_1	345	354	PF02991	0.413
LIG_LIR_Nem_3	345	350	PF02991	0.400
LIG_LIR_Nem_3	378	384	PF02991	0.498
LIG_LIR_Nem_3	516	522	PF02991	0.521
LIG_MLH1_MIPbox_1	515	519	PF16413	0.504
LIG_PALB2_WD40_1	394	402	PF16756	0.433
LIG_PCNA_yPIPBox_3	392	404	PF02747	0.439
LIG_PDZ_Class_3	864	869	PF00595	0.655
LIG_Pex14_1	213	217	PF04695	0.642
LIG_Pex14_2	377	381	PF04695	0.472
LIG_PTB_Apo_2	345	352	PF02174	0.403
LIG_PTB_Phospho_1	345	351	PF10480	0.403
LIG_Rb_LxCxE_1	719	738	PF01857	0.541
LIG_REV1ctd_RIR_1	517	524	PF16727	0.479
LIG_SH2_CRK	347	351	PF00017	0.403
LIG_SH2_CRK	457	461	PF00017	0.408
LIG_SH2_GRB2like	428	431	PF00017	0.434
LIG_SH2_NCK_1	834	838	PF00017	0.567
LIG_SH2_SRC	135	138	PF00017	0.635
LIG_SH2_SRC	349	352	PF00017	0.402
LIG_SH2_SRC	428	431	PF00017	0.305
LIG_SH2_SRC	463	466	PF00017	0.442
LIG_SH2_SRC	834	837	PF00017	0.550
LIG_SH2_STAP1	501	505	PF00017	0.475
LIG_SH2_STAP1	596	600	PF00017	0.765
LIG_SH2_STAT5	129	132	PF00017	0.669
LIG_SH2_STAT5	349	352	PF00017	0.402
LIG_SH2_STAT5	413	416	PF00017	0.424
LIG_SH3_3	114	120	PF00018	0.634
LIG_SH3_3	127	133	PF00018	0.573
LIG_SH3_3	216	222	PF00018	0.560
LIG_SH3_3	282	288	PF00018	0.673
LIG_SH3_3	473	479	PF00018	0.438
LIG_SH3_3	569	575	PF00018	0.656
LIG_SH3_3	651	657	PF00018	0.734
LIG_SH3_3	680	686	PF00018	0.707
LIG_SH3_3	761	767	PF00018	0.767
LIG_SH3_3	77	83	PF00018	0.556
LIG_SH3_3	90	96	PF00018	0.587
LIG_Sin3_3	737	744	PF02671	0.542
LIG_SUMO_SIM_anti_2	38	45	PF11976	0.613
LIG_SUMO_SIM_par_1	295	300	PF11976	0.511
LIG_TRAF2_1	367	370	PF00917	0.474
LIG_TRAF2_1	55	58	PF00917	0.766
LIG_TRAF2_1	565	568	PF00917	0.687
LIG_TYR_ITIM	461	466	PF00017	0.431
LIG_WRC_WIRS_1	754	759	PF05994	0.583
MOD_CDC14_SPxK_1	805	808	PF00782	0.671
MOD_CDK_SPK_2	105	110	PF00069	0.571
MOD_CDK_SPK_2	193	198	PF00069	0.639
MOD_CDK_SPK_2	772	777	PF00069	0.674
MOD_CDK_SPxK_1	802	808	PF00069	0.689
MOD_CDK_SPxxK_3	728	735	PF00069	0.606
MOD_CDK_SPxxK_3	772	779	PF00069	0.675
MOD_CK1_1	160	166	PF00069	0.752
MOD_CK1_1	281	287	PF00069	0.612
MOD_CK1_1	3	9	PF00069	0.578
MOD_CK1_1	342	348	PF00069	0.403
MOD_CK1_1	421	427	PF00069	0.524
MOD_CK1_1	613	619	PF00069	0.749
MOD_CK1_1	637	643	PF00069	0.722
MOD_CK1_1	655	661	PF00069	0.662
MOD_CK1_1	670	676	PF00069	0.620
MOD_CK1_1	692	698	PF00069	0.608
MOD_CK1_1	700	706	PF00069	0.622
MOD_CK1_1	796	802	PF00069	0.694
MOD_CK1_1	854	860	PF00069	0.701
MOD_CK1_1	861	867	PF00069	0.635
MOD_CK1_1	99	105	PF00069	0.780
MOD_CK2_1	160	166	PF00069	0.673
MOD_CK2_1	226	232	PF00069	0.620
MOD_CK2_1	23	29	PF00069	0.746
MOD_CK2_1	3	9	PF00069	0.539
MOD_CK2_1	364	370	PF00069	0.450
MOD_CK2_1	535	541	PF00069	0.603
MOD_CK2_1	753	759	PF00069	0.697
MOD_CK2_1	760	766	PF00069	0.519
MOD_GlcNHglycan	122	125	PF01048	0.685
MOD_GlcNHglycan	146	149	PF01048	0.719
MOD_GlcNHglycan	163	166	PF01048	0.670
MOD_GlcNHglycan	247	250	PF01048	0.601
MOD_GlcNHglycan	280	283	PF01048	0.700
MOD_GlcNHglycan	356	359	PF01048	0.515
MOD_GlcNHglycan	420	423	PF01048	0.564
MOD_GlcNHglycan	592	595	PF01048	0.772
MOD_GlcNHglycan	596	599	PF01048	0.731
MOD_GlcNHglycan	612	615	PF01048	0.650
MOD_GlcNHglycan	647	650	PF01048	0.582
MOD_GlcNHglycan	657	660	PF01048	0.610
MOD_GlcNHglycan	690	694	PF01048	0.628
MOD_GlcNHglycan	725	729	PF01048	0.782
MOD_GlcNHglycan	735	738	PF01048	0.688
MOD_GlcNHglycan	98	101	PF01048	0.698
MOD_GSK3_1	105	112	PF00069	0.672
MOD_GSK3_1	157	164	PF00069	0.801
MOD_GSK3_1	222	229	PF00069	0.687
MOD_GSK3_1	23	30	PF00069	0.634
MOD_GSK3_1	245	252	PF00069	0.689
MOD_GSK3_1	265	272	PF00069	0.584
MOD_GSK3_1	277	284	PF00069	0.583
MOD_GSK3_1	304	311	PF00069	0.474
MOD_GSK3_1	387	394	PF00069	0.492
MOD_GSK3_1	478	485	PF00069	0.563
MOD_GSK3_1	552	559	PF00069	0.707
MOD_GSK3_1	590	597	PF00069	0.798
MOD_GSK3_1	635	642	PF00069	0.683
MOD_GSK3_1	724	731	PF00069	0.734
MOD_GSK3_1	735	742	PF00069	0.612
MOD_GSK3_1	793	800	PF00069	0.714
MOD_GSK3_1	802	809	PF00069	0.727
MOD_GSK3_1	851	858	PF00069	0.680
MOD_GSK3_1	92	99	PF00069	0.603
MOD_N-GLC_1	110	115	PF02516	0.687
MOD_N-GLC_1	391	396	PF02516	0.441
MOD_N-GLC_1	429	434	PF02516	0.481
MOD_N-GLC_1	588	593	PF02516	0.626
MOD_N-GLC_1	859	864	PF02516	0.665
MOD_N-GLC_2	785	787	PF02516	0.639
MOD_NEK2_1	1	6	PF00069	0.588
MOD_NEK2_1	328	333	PF00069	0.503
MOD_NEK2_1	354	359	PF00069	0.518
MOD_NEK2_1	603	608	PF00069	0.621
MOD_NEK2_1	669	674	PF00069	0.640
MOD_NEK2_1	98	103	PF00069	0.629
MOD_NEK2_2	483	488	PF00069	0.461
MOD_NEK2_2	697	702	PF00069	0.627
MOD_PIKK_1	177	183	PF00454	0.770
MOD_PIKK_1	207	213	PF00454	0.650
MOD_PIKK_1	240	246	PF00454	0.635
MOD_PIKK_1	364	370	PF00454	0.450
MOD_PIKK_1	503	509	PF00454	0.574
MOD_PIKK_1	778	784	PF00454	0.660
MOD_PIKK_1	797	803	PF00454	0.544
MOD_PKA_1	226	232	PF00069	0.620
MOD_PKA_1	503	509	PF00069	0.463
MOD_PKA_1	535	541	PF00069	0.616
MOD_PKA_2	109	115	PF00069	0.684
MOD_PKA_2	160	166	PF00069	0.667
MOD_PKA_2	167	173	PF00069	0.672
MOD_PKA_2	232	238	PF00069	0.505
MOD_PKA_2	635	641	PF00069	0.663
MOD_PKB_1	240	248	PF00069	0.642
MOD_Plk_1	110	116	PF00069	0.629
MOD_Plk_1	37	43	PF00069	0.560
MOD_Plk_1	391	397	PF00069	0.453
MOD_Plk_1	483	489	PF00069	0.459
MOD_Plk_4	269	275	PF00069	0.609
MOD_Plk_4	342	348	PF00069	0.532
MOD_Plk_4	349	355	PF00069	0.441
MOD_Plk_4	370	376	PF00069	0.491
MOD_Plk_4	391	397	PF00069	0.475
MOD_Plk_4	483	489	PF00069	0.459
MOD_Plk_4	598	604	PF00069	0.811
MOD_Plk_4	735	741	PF00069	0.548
MOD_ProDKin_1	105	111	PF00069	0.550
MOD_ProDKin_1	193	199	PF00069	0.639
MOD_ProDKin_1	281	287	PF00069	0.633
MOD_ProDKin_1	51	57	PF00069	0.651
MOD_ProDKin_1	513	519	PF00069	0.508
MOD_ProDKin_1	588	594	PF00069	0.654
MOD_ProDKin_1	650	656	PF00069	0.719
MOD_ProDKin_1	658	664	PF00069	0.659
MOD_ProDKin_1	670	676	PF00069	0.658
MOD_ProDKin_1	728	734	PF00069	0.723
MOD_ProDKin_1	765	771	PF00069	0.695
MOD_ProDKin_1	772	778	PF00069	0.780
MOD_ProDKin_1	793	799	PF00069	0.699
MOD_ProDKin_1	802	808	PF00069	0.701
MOD_ProDKin_1	92	98	PF00069	0.624
MOD_SUMO_for_1	701	704	PF00179	0.565
MOD_SUMO_rev_2	511	517	PF00179	0.476
MOD_SUMO_rev_2	567	572	PF00179	0.583
TRG_DiLeu_BaEn_3	369	375	PF01217	0.462
TRG_DiLeu_BaLyEn_6	323	328	PF01217	0.467
TRG_ENDOCYTIC_2	347	350	PF00928	0.403
TRG_ENDOCYTIC_2	351	354	PF00928	0.395
TRG_ENDOCYTIC_2	463	466	PF00928	0.442
TRG_ER_diArg_1	239	242	PF00400	0.623
TRG_ER_diArg_1	408	411	PF00400	0.449
TRG_NLS_MonoExtN_4	532	539	PF00514	0.637

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4H4M0	Leishmania braziliensis	61%	100%
E9AG67	Leishmania infantum	99%	100%
E9AKT3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%
Q4QJ24	Leishmania major	88%	100%