Surface_antigen-like_protein/GeneDB:LmjF.05.1215

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

surface antigen-like protein

Species:

Leishmania donovani

UniProt:

A0A3S7WPB2_LEIDO

TriTrypDb:

LdBPK_051210.1 , LdCL_050017500 , LDHU3_05.1390

Length:

284

Annotations

Annotations by Jardim et al.

Plasma membrane, Surface antigen-like

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 55

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 16

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	yes	yes: 24, no: 5
NetGPI	no	yes: 0, no: 29

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Cellular components
Term	Name	Level	Count
GO:0005929	cilium	4	30
GO:0016020	membrane	2	9
GO:0042995	cell projection	2	30
GO:0043226	organelle	2	30
GO:0043227	membrane-bounded organelle	3	30
GO:0110165	cellular anatomical entity	1	30
GO:0120025	plasma membrane bounded cell projection	3	30

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Expansion

Sequence features

A0A3S7WPB2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WPB2

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	96	100	PF00656	0.341
DOC_CDC14_PxL_1	43	51	PF14671	0.334
DOC_MAPK_gen_1	126	135	PF00069	0.397
DOC_MAPK_MEF2A_6	44	51	PF00069	0.324
DOC_PP1_RVXF_1	130	136	PF00149	0.349
DOC_USP7_MATH_1	192	196	PF00917	0.448
DOC_USP7_MATH_1	21	25	PF00917	0.533
DOC_USP7_MATH_1	278	282	PF00917	0.319
DOC_USP7_MATH_1	69	73	PF00917	0.420
DOC_USP7_MATH_2	145	151	PF00917	0.340

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2E6	Leptomonas seymouri	28%	100%
A0A0N0P2L4	Leptomonas seymouri	27%	96%
A0A0N0P4M2	Leptomonas seymouri	32%	100%
A0A0S4IVH1	Bodo saltans	28%	100%
A0A1X0NKN8	Trypanosomatidae	39%	99%
A0A3Q8I9A6	Leishmania donovani	23%	100%
A0A3Q8I9D0	Leishmania donovani	30%	100%
A0A3Q8IIJ9	Leishmania donovani	25%	100%
A0A3S5H6D6	Leishmania donovani	29%	100%
A0A3S7WP69	Leishmania donovani	33%	100%

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