Protein phosphatase type 1 regulator-like protein

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

protein phosphatase type 1 regulator-like protein

Species:

Leishmania donovani

UniProt:

A0A3S7WPA7_LEIDO

TriTrypDb:

LdBPK_051200.1 , LdCL_050017400 , LDHU3_05.1360

Length:

396

Annotations

Annotations by Jardim et al.

Phosphatase, phosphatase type 1 regulator-like

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	yes	yes: 6
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 16

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Show entries

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0005929	cilium	4	11
GO:0031974	membrane-enclosed lumen	2	1
GO:0031981	nuclear lumen	5	1
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	1
GO:0042995	cell projection	2	11
GO:0043226	organelle	2	11
GO:0043227	membrane-bounded organelle	3	11
GO:0043233	organelle lumen	3	1
GO:0070013	intracellular organelle lumen	4	1

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Expansion

Sequence features

A0A3S7WPA7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WPA7

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	168	172	PF00656	0.449
CLV_C14_Caspase3-7	191	195	PF00656	0.559
CLV_C14_Caspase3-7	234	238	PF00656	0.453
CLV_C14_Caspase3-7	35	39	PF00656	0.827
CLV_C14_Caspase3-7	372	376	PF00656	0.455
CLV_NRD_NRD_1	122	124	PF00675	0.441
CLV_NRD_NRD_1	164	166	PF00675	0.570
CLV_NRD_NRD_1	245	247	PF00675	0.485
CLV_NRD_NRD_1	393	395	PF00675	0.651
CLV_NRD_NRD_1	93	95	PF00675	0.432

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2J8	Leptomonas seymouri	76%	99%
A0A0S4IT07	Bodo saltans	57%	100%
A0A1X0NLS5	Trypanosomatidae	60%	99%
A0A3R7JZE2	Trypanosoma rangeli	59%	99%
A4H4G5	Leishmania braziliensis	92%	100%
A4HSP2	Leishmania infantum	100%	100%
C9ZNE6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	57%	98%
E9AKM7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	97%	100%
O35125	Mus musculus	28%	100%
P21793	Bos taurus	27%	100%

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