LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7WP11_LEIDO
TriTrypDb:
LdBPK_050310.1 * , LdCL_050008000 , LDHU3_05.0360
Length:
943

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WP11
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WP11

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 497 501 PF00656 0.625
CLV_C14_Caspase3-7 682 686 PF00656 0.620
CLV_C14_Caspase3-7 799 803 PF00656 0.573
CLV_C14_Caspase3-7 858 862 PF00656 0.507
CLV_NRD_NRD_1 268 270 PF00675 0.630
CLV_NRD_NRD_1 468 470 PF00675 0.687
CLV_NRD_NRD_1 519 521 PF00675 0.611
CLV_NRD_NRD_1 529 531 PF00675 0.631
CLV_NRD_NRD_1 576 578 PF00675 0.619
CLV_NRD_NRD_1 662 664 PF00675 0.697
CLV_NRD_NRD_1 760 762 PF00675 0.607
CLV_NRD_NRD_1 79 81 PF00675 0.489
CLV_NRD_NRD_1 884 886 PF00675 0.510
CLV_PCSK_FUR_1 659 663 PF00082 0.604
CLV_PCSK_KEX2_1 268 270 PF00082 0.759
CLV_PCSK_KEX2_1 468 470 PF00082 0.687
CLV_PCSK_KEX2_1 519 521 PF00082 0.611
CLV_PCSK_KEX2_1 528 530 PF00082 0.628
CLV_PCSK_KEX2_1 576 578 PF00082 0.619
CLV_PCSK_KEX2_1 661 663 PF00082 0.691
CLV_PCSK_KEX2_1 760 762 PF00082 0.608
CLV_PCSK_KEX2_1 79 81 PF00082 0.489
CLV_PCSK_KEX2_1 883 885 PF00082 0.513
CLV_PCSK_PC1ET2_1 661 663 PF00082 0.562
CLV_PCSK_PC1ET2_1 883 885 PF00082 0.513
CLV_PCSK_PC7_1 515 521 PF00082 0.658
CLV_PCSK_PC7_1 75 81 PF00082 0.490
CLV_PCSK_SKI1_1 20 24 PF00082 0.457
CLV_PCSK_SKI1_1 301 305 PF00082 0.562
CLV_PCSK_SKI1_1 834 838 PF00082 0.599
CLV_PCSK_SKI1_1 855 859 PF00082 0.543
DEG_APCC_DBOX_1 19 27 PF00400 0.457
DEG_Nend_UBRbox_1 1 4 PF02207 0.450
DEG_SCF_FBW7_1 12 19 PF00400 0.454
DEG_SPOP_SBC_1 609 613 PF00917 0.549
DEG_SPOP_SBC_1 698 702 PF00917 0.491
DOC_ANK_TNKS_1 277 284 PF00023 0.559
DOC_CKS1_1 13 18 PF01111 0.452
DOC_CYCLIN_RxL_1 17 25 PF00134 0.444
DOC_CYCLIN_RxL_1 831 840 PF00134 0.603
DOC_CYCLIN_RxL_1 850 861 PF00134 0.444
DOC_CYCLIN_yCln2_LP_2 203 209 PF00134 0.632
DOC_CYCLIN_yCln2_LP_2 631 637 PF00134 0.643
DOC_CYCLIN_yCln2_LP_2 907 913 PF00134 0.502
DOC_MAPK_gen_1 468 476 PF00069 0.679
DOC_MAPK_gen_1 850 859 PF00069 0.592
DOC_PP1_RVXF_1 131 137 PF00149 0.505
DOC_PP1_RVXF_1 18 25 PF00149 0.444
DOC_PP1_RVXF_1 853 860 PF00149 0.584
DOC_PP2B_LxvP_1 203 206 PF13499 0.615
DOC_PP2B_LxvP_1 247 250 PF13499 0.601
DOC_PP2B_LxvP_1 489 492 PF13499 0.620
DOC_PP2B_LxvP_1 631 634 PF13499 0.612
DOC_PP2B_LxvP_1 726 729 PF13499 0.670
DOC_PP2B_LxvP_1 830 833 PF13499 0.567
DOC_PP2B_LxvP_1 907 910 PF13499 0.499
DOC_PP4_FxxP_1 593 596 PF00568 0.553
DOC_USP7_MATH_1 101 105 PF00917 0.510
DOC_USP7_MATH_1 111 115 PF00917 0.544
DOC_USP7_MATH_1 166 170 PF00917 0.620
DOC_USP7_MATH_1 191 195 PF00917 0.543
DOC_USP7_MATH_1 212 216 PF00917 0.689
DOC_USP7_MATH_1 256 260 PF00917 0.588
DOC_USP7_MATH_1 282 286 PF00917 0.638
DOC_USP7_MATH_1 323 327 PF00917 0.641
DOC_USP7_MATH_1 37 41 PF00917 0.489
DOC_USP7_MATH_1 434 438 PF00917 0.660
DOC_USP7_MATH_1 507 511 PF00917 0.785
DOC_USP7_MATH_1 609 613 PF00917 0.681
DOC_USP7_MATH_1 638 642 PF00917 0.635
DOC_USP7_MATH_1 671 675 PF00917 0.621
DOC_USP7_MATH_1 698 702 PF00917 0.543
DOC_USP7_MATH_1 772 776 PF00917 0.667
DOC_USP7_MATH_1 921 925 PF00917 0.501
DOC_USP7_MATH_1 929 933 PF00917 0.501
DOC_USP7_UBL2_3 77 81 PF12436 0.488
DOC_USP7_UBL2_3 930 934 PF12436 0.508
DOC_WW_Pin1_4 112 117 PF00397 0.568
DOC_WW_Pin1_4 12 17 PF00397 0.454
DOC_WW_Pin1_4 121 126 PF00397 0.536
DOC_WW_Pin1_4 146 151 PF00397 0.543
DOC_WW_Pin1_4 220 225 PF00397 0.624
DOC_WW_Pin1_4 347 352 PF00397 0.627
DOC_WW_Pin1_4 354 359 PF00397 0.592
DOC_WW_Pin1_4 381 386 PF00397 0.602
DOC_WW_Pin1_4 411 416 PF00397 0.593
DOC_WW_Pin1_4 518 523 PF00397 0.735
DOC_WW_Pin1_4 585 590 PF00397 0.658
DOC_WW_Pin1_4 61 66 PF00397 0.511
DOC_WW_Pin1_4 610 615 PF00397 0.603
DOC_WW_Pin1_4 694 699 PF00397 0.583
DOC_WW_Pin1_4 749 754 PF00397 0.667
DOC_WW_Pin1_4 759 764 PF00397 0.525
DOC_WW_Pin1_4 828 833 PF00397 0.598
DOC_WW_Pin1_4 835 840 PF00397 0.541
DOC_WW_Pin1_4 902 907 PF00397 0.493
LIG_14-3-3_CanoR_1 110 116 PF00244 0.540
LIG_14-3-3_CanoR_1 123 129 PF00244 0.504
LIG_14-3-3_CanoR_1 216 221 PF00244 0.655
LIG_14-3-3_CanoR_1 226 230 PF00244 0.488
LIG_14-3-3_CanoR_1 268 272 PF00244 0.568
LIG_14-3-3_CanoR_1 855 860 PF00244 0.529
LIG_14-3-3_CanoR_1 98 105 PF00244 0.503
LIG_BRCT_BRCA1_1 20 24 PF00533 0.456
LIG_FHA_1 13 19 PF00498 0.451
LIG_FHA_1 367 373 PF00498 0.650
LIG_FHA_1 412 418 PF00498 0.790
LIG_FHA_1 58 64 PF00498 0.502
LIG_FHA_1 586 592 PF00498 0.595
LIG_FHA_1 621 627 PF00498 0.546
LIG_FHA_1 743 749 PF00498 0.591
LIG_FHA_1 858 864 PF00498 0.542
LIG_FHA_2 166 172 PF00498 0.576
LIG_FHA_2 313 319 PF00498 0.659
LIG_FHA_2 772 778 PF00498 0.667
LIG_FHA_2 797 803 PF00498 0.595
LIG_FHA_2 856 862 PF00498 0.585
LIG_FHA_2 98 104 PF00498 0.475
LIG_LIR_Apic_2 482 488 PF02991 0.608
LIG_LIR_Apic_2 590 596 PF02991 0.637
LIG_LIR_Apic_2 693 698 PF02991 0.527
LIG_LIR_Gen_1 21 30 PF02991 0.449
LIG_LIR_Gen_1 215 224 PF02991 0.596
LIG_LIR_Gen_1 646 655 PF02991 0.539
LIG_LIR_Gen_1 92 101 PF02991 0.469
LIG_LIR_Nem_3 21 27 PF02991 0.444
LIG_LIR_Nem_3 215 220 PF02991 0.613
LIG_LIR_Nem_3 590 595 PF02991 0.644
LIG_LIR_Nem_3 646 651 PF02991 0.551
LIG_LIR_Nem_3 704 710 PF02991 0.475
LIG_LIR_Nem_3 767 771 PF02991 0.646
LIG_LIR_Nem_3 821 826 PF02991 0.668
LIG_LIR_Nem_3 92 96 PF02991 0.470
LIG_MYND_1 208 212 PF01753 0.605
LIG_MYND_1 415 419 PF01753 0.545
LIG_Pex14_1 706 710 PF04695 0.497
LIG_Pex14_2 571 575 PF04695 0.640
LIG_SH2_CRK 648 652 PF00017 0.535
LIG_SH2_CRK 695 699 PF00017 0.519
LIG_SH2_NCK_1 582 586 PF00017 0.644
LIG_SH2_PTP2 768 771 PF00017 0.588
LIG_SH2_SRC 432 435 PF00017 0.635
LIG_SH2_STAP1 187 191 PF00017 0.565
LIG_SH2_STAP1 648 652 PF00017 0.535
LIG_SH2_STAT5 432 435 PF00017 0.745
LIG_SH2_STAT5 582 585 PF00017 0.643
LIG_SH2_STAT5 650 653 PF00017 0.527
LIG_SH2_STAT5 695 698 PF00017 0.522
LIG_SH2_STAT5 768 771 PF00017 0.572
LIG_SH3_1 10 16 PF00018 0.458
LIG_SH3_1 413 419 PF00018 0.681
LIG_SH3_3 10 16 PF00018 0.458
LIG_SH3_3 110 116 PF00018 0.577
LIG_SH3_3 119 125 PF00018 0.534
LIG_SH3_3 413 419 PF00018 0.681
LIG_SH3_3 537 543 PF00018 0.708
LIG_SH3_3 62 68 PF00018 0.507
LIG_SH3_3 623 629 PF00018 0.546
LIG_SH3_3 712 718 PF00018 0.515
LIG_SH3_3 819 825 PF00018 0.731
LIG_SH3_3 903 909 PF00018 0.493
LIG_SUMO_SIM_anti_2 342 348 PF11976 0.530
LIG_SUMO_SIM_par_1 238 244 PF11976 0.607
LIG_TRAF2_1 168 171 PF00917 0.626
LIG_TRAF2_1 493 496 PF00917 0.563
LIG_TRAF2_1 867 870 PF00917 0.575
LIG_TRFH_1 828 832 PF08558 0.575
LIG_WRC_WIRS_1 242 247 PF05994 0.634
LIG_WW_3 120 124 PF00397 0.551
LIG_WW_3 831 835 PF00397 0.640
LIG_WW_3 850 854 PF00397 0.453
MOD_CDC14_SPxK_1 223 226 PF00782 0.560
MOD_CDC14_SPxK_1 831 834 PF00782 0.601
MOD_CDK_SPK_2 518 523 PF00069 0.687
MOD_CDK_SPxK_1 220 226 PF00069 0.568
MOD_CDK_SPxK_1 828 834 PF00069 0.605
MOD_CDK_SPxxK_3 347 354 PF00069 0.581
MOD_CDK_SPxxK_3 905 912 PF00069 0.499
MOD_CK1_1 114 120 PF00069 0.557
MOD_CK1_1 124 130 PF00069 0.505
MOD_CK1_1 182 188 PF00069 0.543
MOD_CK1_1 241 247 PF00069 0.517
MOD_CK1_1 342 348 PF00069 0.530
MOD_CK1_1 350 356 PF00069 0.571
MOD_CK1_1 435 441 PF00069 0.666
MOD_CK1_1 51 57 PF00069 0.480
MOD_CK1_1 597 603 PF00069 0.681
MOD_CK1_1 612 618 PF00069 0.539
MOD_CK1_1 646 652 PF00069 0.622
MOD_CK1_1 679 685 PF00069 0.820
MOD_CK1_1 697 703 PF00069 0.438
MOD_CK1_1 752 758 PF00069 0.652
MOD_CK1_1 835 841 PF00069 0.567
MOD_CK1_1 924 930 PF00069 0.503
MOD_CK2_1 165 171 PF00069 0.563
MOD_CK2_1 258 264 PF00069 0.674
MOD_CK2_1 312 318 PF00069 0.605
MOD_CK2_1 507 513 PF00069 0.690
MOD_CK2_1 51 57 PF00069 0.480
MOD_CK2_1 621 627 PF00069 0.577
MOD_CK2_1 771 777 PF00069 0.536
MOD_CK2_1 97 103 PF00069 0.472
MOD_Cter_Amidation 659 662 PF01082 0.552
MOD_Cter_Amidation 881 884 PF01082 0.516
MOD_DYRK1A_RPxSP_1 354 358 PF00069 0.615
MOD_GlcNHglycan 193 196 PF01048 0.578
MOD_GlcNHglycan 279 282 PF01048 0.638
MOD_GlcNHglycan 284 287 PF01048 0.652
MOD_GlcNHglycan 309 312 PF01048 0.662
MOD_GlcNHglycan 437 440 PF01048 0.591
MOD_GlcNHglycan 456 460 PF01048 0.564
MOD_GlcNHglycan 465 468 PF01048 0.735
MOD_GlcNHglycan 471 474 PF01048 0.565
MOD_GlcNHglycan 482 485 PF01048 0.600
MOD_GlcNHglycan 500 503 PF01048 0.677
MOD_GlcNHglycan 53 56 PF01048 0.477
MOD_GlcNHglycan 645 648 PF01048 0.741
MOD_GlcNHglycan 688 691 PF01048 0.600
MOD_GlcNHglycan 701 704 PF01048 0.507
MOD_GlcNHglycan 774 777 PF01048 0.721
MOD_GlcNHglycan 779 782 PF01048 0.596
MOD_GlcNHglycan 785 788 PF01048 0.492
MOD_GlcNHglycan 81 84 PF01048 0.480
MOD_GlcNHglycan 841 844 PF01048 0.544
MOD_GlcNHglycan 926 929 PF01048 0.497
MOD_GlcNHglycan 931 934 PF01048 0.503
MOD_GSK3_1 111 118 PF00069 0.551
MOD_GSK3_1 12 19 PF00069 0.454
MOD_GSK3_1 124 131 PF00069 0.514
MOD_GSK3_1 146 153 PF00069 0.544
MOD_GSK3_1 173 180 PF00069 0.601
MOD_GSK3_1 193 200 PF00069 0.538
MOD_GSK3_1 212 219 PF00069 0.611
MOD_GSK3_1 303 310 PF00069 0.543
MOD_GSK3_1 350 357 PF00069 0.574
MOD_GSK3_1 428 435 PF00069 0.564
MOD_GSK3_1 44 51 PF00069 0.486
MOD_GSK3_1 557 564 PF00069 0.697
MOD_GSK3_1 57 64 PF00069 0.487
MOD_GSK3_1 583 590 PF00069 0.677
MOD_GSK3_1 608 615 PF00069 0.686
MOD_GSK3_1 616 623 PF00069 0.506
MOD_GSK3_1 646 653 PF00069 0.571
MOD_GSK3_1 686 693 PF00069 0.595
MOD_GSK3_1 694 701 PF00069 0.541
MOD_GSK3_1 748 755 PF00069 0.643
MOD_GSK3_1 772 779 PF00069 0.628
MOD_GSK3_1 828 835 PF00069 0.690
MOD_GSK3_1 924 931 PF00069 0.504
MOD_GSK3_1 97 104 PF00069 0.497
MOD_N-GLC_1 686 691 PF02516 0.672
MOD_NEK2_1 128 133 PF00069 0.505
MOD_NEK2_1 18 23 PF00069 0.453
MOD_NEK2_1 181 186 PF00069 0.522
MOD_NEK2_1 240 245 PF00069 0.625
MOD_NEK2_1 303 308 PF00069 0.545
MOD_NEK2_1 366 371 PF00069 0.718
MOD_NEK2_1 50 55 PF00069 0.482
MOD_NEK2_1 699 704 PF00069 0.476
MOD_NEK2_1 748 753 PF00069 0.653
MOD_NEK2_1 771 776 PF00069 0.702
MOD_NEK2_2 258 263 PF00069 0.553
MOD_NEK2_2 690 695 PF00069 0.537
MOD_PIKK_1 154 160 PF00454 0.562
MOD_PIKK_1 166 172 PF00454 0.589
MOD_PIKK_1 179 185 PF00454 0.479
MOD_PIKK_1 612 618 PF00454 0.602
MOD_PIKK_1 63 69 PF00454 0.493
MOD_PK_1 216 222 PF00069 0.671
MOD_PKA_1 661 667 PF00069 0.610
MOD_PKA_1 79 85 PF00069 0.479
MOD_PKA_1 883 889 PF00069 0.509
MOD_PKA_2 212 218 PF00069 0.687
MOD_PKA_2 225 231 PF00069 0.495
MOD_PKA_2 267 273 PF00069 0.624
MOD_PKA_2 277 283 PF00069 0.542
MOD_PKA_2 480 486 PF00069 0.668
MOD_PKA_2 51 57 PF00069 0.480
MOD_PKA_2 557 563 PF00069 0.695
MOD_PKA_2 661 667 PF00069 0.637
MOD_PKA_2 79 85 PF00069 0.480
MOD_PKA_2 883 889 PF00069 0.509
MOD_PKA_2 97 103 PF00069 0.473
MOD_PKB_1 853 861 PF00069 0.539
MOD_Plk_1 676 682 PF00069 0.653
MOD_Plk_4 124 130 PF00069 0.527
MOD_Plk_4 225 231 PF00069 0.541
MOD_Plk_4 339 345 PF00069 0.585
MOD_Plk_4 366 372 PF00069 0.518
MOD_Plk_4 428 434 PF00069 0.577
MOD_Plk_4 587 593 PF00069 0.650
MOD_Plk_4 594 600 PF00069 0.554
MOD_Plk_4 621 627 PF00069 0.546
MOD_Plk_4 646 652 PF00069 0.622
MOD_Plk_4 764 770 PF00069 0.562
MOD_ProDKin_1 112 118 PF00069 0.569
MOD_ProDKin_1 12 18 PF00069 0.454
MOD_ProDKin_1 121 127 PF00069 0.534
MOD_ProDKin_1 146 152 PF00069 0.546
MOD_ProDKin_1 220 226 PF00069 0.629
MOD_ProDKin_1 347 353 PF00069 0.623
MOD_ProDKin_1 354 360 PF00069 0.587
MOD_ProDKin_1 381 387 PF00069 0.602
MOD_ProDKin_1 411 417 PF00069 0.594
MOD_ProDKin_1 518 524 PF00069 0.738
MOD_ProDKin_1 585 591 PF00069 0.655
MOD_ProDKin_1 61 67 PF00069 0.511
MOD_ProDKin_1 610 616 PF00069 0.602
MOD_ProDKin_1 694 700 PF00069 0.577
MOD_ProDKin_1 749 755 PF00069 0.667
MOD_ProDKin_1 759 765 PF00069 0.522
MOD_ProDKin_1 828 834 PF00069 0.598
MOD_ProDKin_1 835 841 PF00069 0.546
MOD_ProDKin_1 902 908 PF00069 0.493
MOD_SUMO_for_1 372 375 PF00179 0.588
TRG_DiLeu_BaEn_1 627 632 PF01217 0.602
TRG_DiLeu_BaLyEn_6 13 18 PF01217 0.440
TRG_DiLeu_BaLyEn_6 147 152 PF01217 0.526
TRG_DiLeu_BaLyEn_6 205 210 PF01217 0.604
TRG_ENDOCYTIC_2 648 651 PF00928 0.540
TRG_ENDOCYTIC_2 768 771 PF00928 0.648
TRG_ER_diArg_1 468 470 PF00400 0.602
TRG_ER_diArg_1 518 520 PF00400 0.685
TRG_ER_diArg_1 527 530 PF00400 0.558
TRG_ER_diArg_1 575 577 PF00400 0.773
TRG_ER_diArg_1 662 665 PF00400 0.693
TRG_ER_diArg_1 759 761 PF00400 0.622
TRG_ER_diArg_1 78 80 PF00400 0.487
TRG_ER_diArg_1 852 855 PF00400 0.642
TRG_ER_diArg_1 884 887 PF00400 0.511
TRG_NLS_MonoExtC_3 660 665 PF00514 0.562
TRG_NLS_MonoExtC_3 882 887 PF00514 0.512
TRG_NLS_MonoExtN_4 659 665 PF00514 0.559
TRG_Pf-PMV_PEXEL_1 509 513 PF00026 0.596

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PCQ8 Leptomonas seymouri 33% 100%
A4H475 Leishmania braziliensis 70% 98%
A4HSF0 Leishmania infantum 100% 100%
E9AKD6 Leishmania mexicana (strain MHOM/GT/2001/U1103) 79% 96%
Q4QJH2 Leishmania major 77% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS