LeishMANIAdb
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Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hypothetical_protein_conserved
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7WP10_LEIDO
TriTrypDb:
LdBPK_050370.1 * , LdCL_050008700 , LDHU3_05.0420
Length:
328

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7WP10
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7WP10

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 160 164 PF00656 0.588
CLV_C14_Caspase3-7 187 191 PF00656 0.761
CLV_C14_Caspase3-7 296 300 PF00656 0.739
CLV_NRD_NRD_1 246 248 PF00675 0.827
CLV_NRD_NRD_1 38 40 PF00675 0.652
CLV_PCSK_KEX2_1 246 248 PF00082 0.827
CLV_PCSK_KEX2_1 37 39 PF00082 0.653
CLV_PCSK_PC1ET2_1 37 39 PF00082 0.653
CLV_PCSK_PC7_1 33 39 PF00082 0.649
CLV_PCSK_SKI1_1 129 133 PF00082 0.601
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P3H3 Leptomonas seymouri 37% 100%
A4H482 Leishmania braziliensis 66% 99%
A4HSF9 Leishmania infantum 100% 100%
E9AKE3 Leishmania mexicana (strain MHOM/GT/2001/U1103) 84% 100%
Q4QJG5 Leishmania major 91% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS